WO2012045067A3 - Mammalian genes involved in infection - Google Patents

Mammalian genes involved in infection Download PDF

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Publication number
WO2012045067A3
WO2012045067A3 PCT/US2011/054568 US2011054568W WO2012045067A3 WO 2012045067 A3 WO2012045067 A3 WO 2012045067A3 US 2011054568 W US2011054568 W US 2011054568W WO 2012045067 A3 WO2012045067 A3 WO 2012045067A3
Authority
WO
WIPO (PCT)
Prior art keywords
infection
genes involved
mammalian genes
involved
sequences
Prior art date
Application number
PCT/US2011/054568
Other languages
French (fr)
Other versions
WO2012045067A2 (en
Inventor
Donald Rubin
Thomas Hodge
R. Jeff Hogan
Original Assignee
Zirus, Inc.
Vanderbilt University
University Of Georgia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zirus, Inc., Vanderbilt University, University Of Georgia filed Critical Zirus, Inc.
Publication of WO2012045067A2 publication Critical patent/WO2012045067A2/en
Publication of WO2012045067A3 publication Critical patent/WO2012045067A3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering N.A.
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae

Abstract

The present invention relates to nucleic acid sequences and cellular proteins encoded by these sequences that are involved in infection or are otherwise associated with the life cycle of one or more pathogens.
PCT/US2011/054568 2010-10-01 2011-10-03 Mammalian genes involved in infection WO2012045067A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38865710P 2010-10-01 2010-10-01
US61/388,657 2010-10-01

Publications (2)

Publication Number Publication Date
WO2012045067A2 WO2012045067A2 (en) 2012-04-05
WO2012045067A3 true WO2012045067A3 (en) 2012-11-22

Family

ID=45893794

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/054568 WO2012045067A2 (en) 2010-10-01 2011-10-03 Mammalian genes involved in infection

Country Status (1)

Country Link
WO (1) WO2012045067A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013166264A2 (en) * 2012-05-02 2013-11-07 University Of Georgia Research Foundation, Inc. Methods for altering virus replication
WO2019095064A1 (en) * 2017-11-15 2019-05-23 UNIVERSITé LAVAL Use of srsf3 agents for the treatment and/or prevention of neurological conditions, cancer, bacterial infections or viral infections

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5463078A (en) * 1993-02-15 1995-10-31 Ajinomoto Co., Inc. Anisomycin derivatives and anticancer agents, antifungal agents and antiprotozoan agents containing the same
US20040038201A1 (en) * 2002-01-22 2004-02-26 Whitehead Institute For Biomedical Research Diagnostic and therapeutic applications for biomarkers of infection
US20050226889A1 (en) * 1998-06-04 2005-10-13 Vanderbilt University Inhibition of viral infection and spread with viral and RhoA-derived peptides
WO2006047673A2 (en) * 2004-10-27 2006-05-04 Vanderbilt University Mammalian genes involved in infection
US20060257872A1 (en) * 2002-11-18 2006-11-16 Hodge Thomas W Cell lines and host nucleic acid sequences related to infectious disease

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5463078A (en) * 1993-02-15 1995-10-31 Ajinomoto Co., Inc. Anisomycin derivatives and anticancer agents, antifungal agents and antiprotozoan agents containing the same
US20050226889A1 (en) * 1998-06-04 2005-10-13 Vanderbilt University Inhibition of viral infection and spread with viral and RhoA-derived peptides
US20040038201A1 (en) * 2002-01-22 2004-02-26 Whitehead Institute For Biomedical Research Diagnostic and therapeutic applications for biomarkers of infection
US20060257872A1 (en) * 2002-11-18 2006-11-16 Hodge Thomas W Cell lines and host nucleic acid sequences related to infectious disease
WO2006047673A2 (en) * 2004-10-27 2006-05-04 Vanderbilt University Mammalian genes involved in infection

Also Published As

Publication number Publication date
WO2012045067A2 (en) 2012-04-05

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