WO2012036884A3 - Bioproduction of aromatic chemicals from lignin-derived compounds - Google Patents

Bioproduction of aromatic chemicals from lignin-derived compounds Download PDF

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Publication number
WO2012036884A3
WO2012036884A3 PCT/US2011/049619 US2011049619W WO2012036884A3 WO 2012036884 A3 WO2012036884 A3 WO 2012036884A3 US 2011049619 W US2011049619 W US 2011049619W WO 2012036884 A3 WO2012036884 A3 WO 2012036884A3
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WO
WIPO (PCT)
Prior art keywords
lignin
enzymes
derived compounds
bioproduction
bioconversion
Prior art date
Application number
PCT/US2011/049619
Other languages
French (fr)
Other versions
WO2012036884A2 (en
Inventor
Ranjini Chatterjee
Kenneth Zahn
Kenneth Mitchell
Gary Y. Liu
Original Assignee
Aligna Technologies, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aligna Technologies, Inc. filed Critical Aligna Technologies, Inc.
Priority to JP2013529175A priority Critical patent/JP2014506115A/en
Priority to CA2811403A priority patent/CA2811403A1/en
Priority to AU2011302522A priority patent/AU2011302522A1/en
Priority to CN201180044555.0A priority patent/CN103797026A/en
Priority to EP11825655.1A priority patent/EP2616481A4/en
Publication of WO2012036884A2 publication Critical patent/WO2012036884A2/en
Publication of WO2012036884A3 publication Critical patent/WO2012036884A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C12N9/1088—Glutathione transferase (2.5.1.18)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C12P7/28—Acetone-containing products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01018—Glutathione transferase (2.5.1.18)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

The teachings provided herein are generally directed to a method of converting lignin-derived compounds to valuable aromatic chemicals using an enzymatic, bioconversion process. The teachings provide a selection of (i) host cells that are tolerant to the toxic compounds present in lignin fractions; (ii) polypeptides that can be used as enzymes in the bioconversion of the lignin fractions to the aromatic chemical products; (iii) polynucleotides that can be used to transform the host cells to express the selection of polypeptides as enzymes in the bioconversion of the lignin fractions; and (iv) the transformants that express the enzymes.
PCT/US2011/049619 2010-09-15 2011-08-29 Bioproduction of aromatic chemicals from lignin-derived compounds WO2012036884A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2013529175A JP2014506115A (en) 2010-09-15 2011-08-29 Bioproduction of aromatic chemicals from lignin-derived compounds
CA2811403A CA2811403A1 (en) 2010-09-15 2011-08-29 Bioproduction of aromatic chemicals from lignin-derived compounds
AU2011302522A AU2011302522A1 (en) 2010-09-15 2011-08-29 Bioproduction of aromatic chemicals from lignin-derived compounds
CN201180044555.0A CN103797026A (en) 2010-09-15 2011-08-29 Bioproduction of aromatic chemicals from lignin-derived compounds
EP11825655.1A EP2616481A4 (en) 2010-09-15 2011-08-29 Bioproduction of aromatic chemicals from lignin-derived compounds

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US40340010P 2010-09-15 2010-09-15
US61/403,400 2010-09-15
US45570910P 2010-10-25 2010-10-25
US61/455,709 2010-10-25

Publications (2)

Publication Number Publication Date
WO2012036884A2 WO2012036884A2 (en) 2012-03-22
WO2012036884A3 true WO2012036884A3 (en) 2012-08-02

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/049619 WO2012036884A2 (en) 2010-09-15 2011-08-29 Bioproduction of aromatic chemicals from lignin-derived compounds

Country Status (6)

Country Link
EP (1) EP2616481A4 (en)
JP (1) JP2014506115A (en)
CN (1) CN103797026A (en)
AU (1) AU2011302522A1 (en)
CA (1) CA2811403A1 (en)
WO (1) WO2012036884A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014200509A1 (en) * 2013-06-14 2014-12-18 Washington State University Research Foundation Conversion of lignin to phenolic and carboxylate compounds
AU2014288309B9 (en) 2013-07-09 2018-04-26 Toray Industries, Inc. Method for producing saccharide solution
US11267838B2 (en) 2017-04-17 2022-03-08 Board Of Trustees Of Michigan State University Methods for lignin depolymerization using thiols
WO2018204424A1 (en) * 2017-05-01 2018-11-08 National Technology & Engineering Solutions Of Sandia, Llc Novel compositions and methods for synthesizing deep eutectic solvents from lignin derived phenolic compounds
CN109423456B (en) * 2017-08-30 2022-08-19 中国石油化工股份有限公司 Azotobacter chroococcum as well as identification method and application thereof
KR101831966B1 (en) 2017-10-27 2018-02-23 경상대학교산학협력단 Method for producing humified lignin conversion product
CN117285663A (en) * 2023-10-17 2023-12-26 中国石油大学(华东) Method for mildly and stepwise separating lignocellulose biomass components

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ZA811368B (en) 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
NZ201705A (en) 1981-08-31 1986-03-14 Genentech Inc Recombinant dna method for production of hepatitis b surface antigen in yeast
US4943529A (en) 1982-05-19 1990-07-24 Gist-Brocades Nv Kluyveromyces as a host strain
AU2353384A (en) 1983-01-19 1984-07-26 Genentech Inc. Amplification in eukaryotic host cells
US4713339A (en) 1983-01-19 1987-12-15 Genentech, Inc. Polycistronic expression vector construction
DD266710A3 (en) 1983-06-06 1989-04-12 Ve Forschungszentrum Biotechnologie Process for the biotechnical production of alkaline phosphatase
AU3145184A (en) 1983-08-16 1985-02-21 Zymogenetics Inc. High expression of foreign genes in schizosaccharomyces pombe
US4879231A (en) 1984-10-30 1989-11-07 Phillips Petroleum Company Transformation of yeasts of the genus pichia
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US5010182A (en) 1987-07-28 1991-04-23 Chiron Corporation DNA constructs containing a Kluyveromyces alpha factor leader sequence for directing secretion of heterologous polypeptides
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See also references of EP2616481A4 *

Also Published As

Publication number Publication date
EP2616481A2 (en) 2013-07-24
CA2811403A1 (en) 2012-03-22
CN103797026A (en) 2014-05-14
JP2014506115A (en) 2014-03-13
WO2012036884A2 (en) 2012-03-22
EP2616481A4 (en) 2014-04-02
AU2011302522A1 (en) 2013-05-02

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