WO2012024546A3 - Incorporation of health measurments in analysis and interpretation of functional biological response data - Google Patents

Incorporation of health measurments in analysis and interpretation of functional biological response data Download PDF

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Publication number
WO2012024546A3
WO2012024546A3 PCT/US2011/048332 US2011048332W WO2012024546A3 WO 2012024546 A3 WO2012024546 A3 WO 2012024546A3 US 2011048332 W US2011048332 W US 2011048332W WO 2012024546 A3 WO2012024546 A3 WO 2012024546A3
Authority
WO
WIPO (PCT)
Prior art keywords
analysis
health
measurments
interpretation
incorporation
Prior art date
Application number
PCT/US2011/048332
Other languages
French (fr)
Other versions
WO2012024546A2 (en
Inventor
David Rosen
Todd Covey
Santosh Putta
Brent Louie
Original Assignee
Nodality, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nodality, Inc. filed Critical Nodality, Inc.
Publication of WO2012024546A2 publication Critical patent/WO2012024546A2/en
Publication of WO2012024546A3 publication Critical patent/WO2012024546A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways

Abstract

Provided herein are methods for improving the analysis of cell signaling data comprising accounting for the state of health of cells in a sample. In some embodiments, unhealthy cells are eliminated from the analysis of cell signaling data. In other embodiments, cell signaling data are adjusted based on the presence of unhealthy cells a sample.
PCT/US2011/048332 2010-08-18 2011-08-18 Incorporation of health measurments in analysis and interpretation of functional biological response data WO2012024546A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US37461310P 2010-08-18 2010-08-18
US61/374,613 2010-08-18
US201161436534P 2011-01-26 2011-01-26
US61/436,534 2011-01-26

Publications (2)

Publication Number Publication Date
WO2012024546A2 WO2012024546A2 (en) 2012-02-23
WO2012024546A3 true WO2012024546A3 (en) 2012-05-03

Family

ID=45605682

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/048332 WO2012024546A2 (en) 2010-08-18 2011-08-18 Incorporation of health measurments in analysis and interpretation of functional biological response data

Country Status (1)

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WO (1) WO2012024546A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2179037A4 (en) 2007-08-21 2010-12-22 Nodality Inc Methods for diagnosis, prognosis and methods of treatment
EP2304436A1 (en) 2008-07-10 2011-04-06 Nodality, Inc. Methods for diagnosis, prognosis and treatment
US9034257B2 (en) 2008-10-27 2015-05-19 Nodality, Inc. High throughput flow cytometry system and method
US9459246B2 (en) 2009-09-08 2016-10-04 Nodality, Inc. Induced intercellular communication
WO2014036040A2 (en) * 2012-08-27 2014-03-06 Nodality Inc. Methods for diagnosis, prognosis and methods of treatment
US20160230227A1 (en) * 2012-12-21 2016-08-11 The New York Stem Cell Foundation Methods of treating alzheimer's disease
AU2018230686A1 (en) * 2017-03-06 2019-10-17 Talaris Therapeutics, Inc. Methods and compositions for determining the potency of a therapeutic cellular composition
CN107389628B (en) * 2017-06-09 2019-09-24 福建医科大学孟超肝胆医院(福州市传染病医院) A kind of Apoptosis is double-colored to be detected and image probe and its application

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090269773A1 (en) * 2008-04-29 2009-10-29 Nodality, Inc. A Delaware Corporation Methods of determining the health status of an individual

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090269773A1 (en) * 2008-04-29 2009-10-29 Nodality, Inc. A Delaware Corporation Methods of determining the health status of an individual

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SHANKAR ET AL.: "ABT-869, a multitargeted receptor tyrosine kinase inhibitor: inhibition of FLT3 phosphorylation and signaling in acute myeloid leukemia", BLOOD, vol. 109, no. 8, 15 April 2007 (2007-04-15), pages 3400 - 3408 *

Also Published As

Publication number Publication date
WO2012024546A2 (en) 2012-02-23

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