WO2012019268A3 - Composição imunogênica para vacina e kit para teste imunodiagnóstico de leishmaniose visceral - Google Patents

Composição imunogênica para vacina e kit para teste imunodiagnóstico de leishmaniose visceral Download PDF

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Publication number
WO2012019268A3
WO2012019268A3 PCT/BR2011/000294 BR2011000294W WO2012019268A3 WO 2012019268 A3 WO2012019268 A3 WO 2012019268A3 BR 2011000294 W BR2011000294 W BR 2011000294W WO 2012019268 A3 WO2012019268 A3 WO 2012019268A3
Authority
WO
WIPO (PCT)
Prior art keywords
vaccine
immunogenic composition
leishmaniasis
test kit
visceral leishmaniasis
Prior art date
Application number
PCT/BR2011/000294
Other languages
English (en)
French (fr)
Other versions
WO2012019268A2 (pt
Inventor
Ricardo Tostes Gazzinelli
Hélida MONTEIRO DE ANDRADE
Míriam MARIA SILVA COSTA FRANCO
Angélica ROSA FARIA
Original Assignee
Universidade Federal De Minas Gerais - Ufmg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidade Federal De Minas Gerais - Ufmg filed Critical Universidade Federal De Minas Gerais - Ufmg
Publication of WO2012019268A2 publication Critical patent/WO2012019268A2/pt
Publication of WO2012019268A3 publication Critical patent/WO2012019268A3/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/008—Leishmania antigens
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

A presente invenção descreve uma composição imunogênica para vacina e teste imunodiagnóstico de Leishmaniose Visceral. Mais especificamente, a invenção compreende uma vacina e um kit para teste imunodiagnóstico de Leishmaniose, desenvolvidos através da identificação, produção e seleção de novos antígenos por meio de análise proteômica, bioinformática, síntese de peptídeos e imunoensaio. A alta especificidade desses antígenos possibilita a realização de uma vacina eficaz contra Leishmaniose e de um teste imunodiagnóstico mais eficiente para a Leishmaniose Visceral canina ou humana.
PCT/BR2011/000294 2010-08-13 2011-08-12 Composição imunogênica para vacina e kit para teste imunodiagnóstico de leishmaniose visceral WO2012019268A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BRPI1006646-2A BRPI1006646A2 (pt) 2010-08-13 2010-08-13 composição imunogênica para vacina e kit para teste imunodiagnóstico de leishmaniose visceral
BR014100002830 2010-08-13
BR014110002431 2011-08-09

Publications (2)

Publication Number Publication Date
WO2012019268A2 WO2012019268A2 (pt) 2012-02-16
WO2012019268A3 true WO2012019268A3 (pt) 2012-07-26

Family

ID=45936517

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2011/000294 WO2012019268A2 (pt) 2010-08-13 2011-08-12 Composição imunogênica para vacina e kit para teste imunodiagnóstico de leishmaniose visceral

Country Status (2)

Country Link
BR (1) BRPI1006646A2 (pt)
WO (1) WO2012019268A2 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR102013033627B1 (pt) * 2013-12-27 2021-02-09 Universidade Federal De Minas Gerais peptídeos sintéticos, método e kit para imunodiagnóstico da leishmaniose visceral canina e das leishmanioses tegumentar e visceral humana

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965142A (en) * 1995-08-04 1999-10-12 Corixa Corporation Polypeptides and methods for the detection of L. tropica infection
WO2006108720A2 (en) * 2005-04-08 2006-10-19 Institut Pasteur Polypeptides of leishmania major and polynucleotides encoding same and vaccinal, therapeutical and diagnostic applications thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965142A (en) * 1995-08-04 1999-10-12 Corixa Corporation Polypeptides and methods for the detection of L. tropica infection
WO2006108720A2 (en) * 2005-04-08 2006-10-19 Institut Pasteur Polypeptides of leishmania major and polynucleotides encoding same and vaccinal, therapeutical and diagnostic applications thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PEACOCK, CS ET AL.: "Comparative analysis of genomic threre Leishmaria species causing diverse human disease.", NAT GENET., vol. 39, no. 7, 2007, pages 839 - 847 *

Also Published As

Publication number Publication date
WO2012019268A2 (pt) 2012-02-16
BRPI1006646A2 (pt) 2012-04-17

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