WO2012012510A3 - Gene expression profiling for the identification of lung cancer - Google Patents
Gene expression profiling for the identification of lung cancer Download PDFInfo
- Publication number
- WO2012012510A3 WO2012012510A3 PCT/US2011/044648 US2011044648W WO2012012510A3 WO 2012012510 A3 WO2012012510 A3 WO 2012012510A3 US 2011044648 W US2011044648 W US 2011044648W WO 2012012510 A3 WO2012012510 A3 WO 2012012510A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- identification
- gene expression
- lung cancer
- expression profiling
- copd
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Medical Informatics (AREA)
- Pathology (AREA)
- Evolutionary Biology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Wood Science & Technology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
The invention provides gene models useful in the screening of at-risk patients for lung cancers including smokers with and without chronic obstructive pulmonary disease (COPD).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11810327.4A EP2596131A4 (en) | 2010-07-21 | 2011-07-20 | Gene expression profiling for the identification of lung cancer |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36633110P | 2010-07-21 | 2010-07-21 | |
US61/366,331 | 2010-07-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2012012510A2 WO2012012510A2 (en) | 2012-01-26 |
WO2012012510A3 true WO2012012510A3 (en) | 2012-05-24 |
Family
ID=45497433
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2011/044648 WO2012012510A2 (en) | 2010-07-21 | 2011-07-20 | Gene expression profiling for the identification of lung cancer |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP2596131A4 (en) |
WO (1) | WO2012012510A2 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6240804B1 (en) * | 2017-04-13 | 2017-11-29 | 大▲連▼大学 | Filtered feature selection algorithm based on improved information measurement and GA |
CN110699457B (en) * | 2019-10-30 | 2022-11-25 | 深圳瑞科生物科技有限公司 | Primer group and kit for detecting lung cancer |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7871774B2 (en) * | 2005-01-31 | 2011-01-18 | Digital Genomics Inc. | Markers for the diagnosis of lung cancer |
CA2669600A1 (en) * | 2006-11-13 | 2008-05-29 | Source Precision Medicine, Inc. D/B/A Source Mdx | Gene expression profiling for identification, monitoring, and treatment of lung cancer |
-
2011
- 2011-07-20 WO PCT/US2011/044648 patent/WO2012012510A2/en active Application Filing
- 2011-07-20 EP EP11810327.4A patent/EP2596131A4/en not_active Withdrawn
Non-Patent Citations (4)
Title |
---|
GONZALEZ-ARRIAGA, P. ET AL.: "Polymorphism +17C/G in matrix metalloprotease MP8 decreases lung cancer risk.", BMC CANCER, vol. 8, no. 378, 19 December 2008 (2008-12-19) * |
OCAK, S. ET AL.: "High-throughput molecular analysis in lung cancer: insights into biology and potential clinical applications.", EUR. RESPIR. J., vol. 34, no. 2, August 2009 (2009-08-01), pages 489 - 506, XP055072660 * |
OHRI, C. M. ET AL.: "Chemokine receptor expression in tumor islets and stroma in non-small cell lung cancer.", BMC CANCER, vol. 10, no. 172, 29 April 2010 (2010-04-29), XP021075011 * |
YIN, Z. ET AL.: "ERCC2, ERCC1 polymorphisms and haplotypes, cooking oil fume and lung adenocarcinoma risk in Chinese non-smoking females.", J. EXP. CLIN. CANCER RES., vol. 28, no. 153, 14 December 2009 (2009-12-14), XP021070230 * |
Also Published As
Publication number | Publication date |
---|---|
EP2596131A4 (en) | 2013-12-18 |
EP2596131A2 (en) | 2013-05-29 |
WO2012012510A2 (en) | 2012-01-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1252674A1 (en) | Mirna fingerprint in the diagnosis of lung cancer | |
IL261348A (en) | An isolated antibody or fragment thereof that binds cd100, for use in the treatment of an autoimmune disease, an inflammatory disease of cancer | |
IL261313B (en) | Methods of identification and diagnosis of lung disease using classification systems and kits thereof | |
HK1204062A1 (en) | Lung cancer biomarkers and uses thereof | |
IL223295A0 (en) | Lung cancer biomarkers and uses thereof | |
EP3607089A4 (en) | Plasma based protein profiling for early stage lung cancer prognosis | |
HK1208501A1 (en) | Method for the diagnosis, prognosis and treatment of lung cancer metastasis | |
LT2845593T (en) | Pyridine and pyrazine derivative for the treatment of chronic obstructive pulmonary disease | |
HK1133802A1 (en) | Methods of making reconstituted tobacco sheets | |
HK1213976A1 (en) | Prediction of drug sensitivity of lung tumors based on molecular and genetic signatures | |
EP2250287A4 (en) | Detection and prognosis of lung cancer | |
EP2411003A4 (en) | Use of artemisinin derivatives for the treatment of asthma and chronic obstructive pulmonary disease (copd) | |
WO2012125712A3 (en) | Lung tumor classifier for current and former smokers | |
HK1197274A1 (en) | Micro-rna biomarkers for identifying risk of and/or for diagnosing lung tumour and pharmaceutical compositions thereof / rna | |
EP3610260A4 (en) | Biomarker combinations for monitoring chronic obstructive pulmonary disease and/or associated mechanisms | |
EP2744919A4 (en) | Gene signatures for lung cancer prognosis and therapy selection | |
WO2012135841A3 (en) | Emt signatures and predictive markers and method of using the same | |
EP3152560A4 (en) | Non-invasive gene mutation detection in lung cancer patients | |
WO2013049152A3 (en) | Methods for evaluating lung cancer status | |
GB2509682B (en) | Biomarkers useful for detection of types, grades and stages of human breast cancer | |
IL228579A0 (en) | Methods for predicting and improving the survival of gastric cancer patients | |
PL2195645T3 (en) | Method for aiding in the diagnosis and therapy of asthma and lung cancer | |
PL3257953T3 (en) | Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof including gender-based disease identification, assessment, prevention and therapy | |
EP2921858A4 (en) | Method for obtaining data that are useful for the diagnosis, prognosis and classification of patients with chronic obstructive pulmonary disease (copd) and/or lung cancer | |
WO2012012510A3 (en) | Gene expression profiling for the identification of lung cancer |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 11810327 Country of ref document: EP Kind code of ref document: A2 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2011810327 Country of ref document: EP |