WO2011159317A1 - Procédé et appareil pour stimulus vibratoire, tactile et autre localisé pour diminuer la douleur associée à des injections pour des procédures chirurgicales mineures et des traitements cosmétiques au laser - Google Patents

Procédé et appareil pour stimulus vibratoire, tactile et autre localisé pour diminuer la douleur associée à des injections pour des procédures chirurgicales mineures et des traitements cosmétiques au laser Download PDF

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Publication number
WO2011159317A1
WO2011159317A1 PCT/US2010/039234 US2010039234W WO2011159317A1 WO 2011159317 A1 WO2011159317 A1 WO 2011159317A1 US 2010039234 W US2010039234 W US 2010039234W WO 2011159317 A1 WO2011159317 A1 WO 2011159317A1
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Prior art keywords
vibration
handle
vibration head
pain
patient
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PCT/US2010/039234
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English (en)
Inventor
Yehoshua Shachar
Vito Caruso
Winston Wu
Brett Jordan
Kyle Zimmerman
Herwin Chan
Paladin Luboff
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Willow Vibe Llc
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Priority to PCT/US2010/039234 priority Critical patent/WO2011159317A1/fr
Publication of WO2011159317A1 publication Critical patent/WO2011159317A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H7/00—Devices for suction-kneading massage; Devices for massaging the skin by rubbing or brushing not otherwise provided for
    • A61H7/002—Devices for suction-kneading massage; Devices for massaging the skin by rubbing or brushing not otherwise provided for by rubbing or brushing
    • A61H7/004—Devices for suction-kneading massage; Devices for massaging the skin by rubbing or brushing not otherwise provided for by rubbing or brushing power-driven, e.g. electrical
    • A61H7/005—Devices for suction-kneading massage; Devices for massaging the skin by rubbing or brushing not otherwise provided for by rubbing or brushing power-driven, e.g. electrical hand-held
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/203—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser applying laser energy to the outside of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
    • A61H23/02—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
    • A61H23/0254—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive with rotary motor
    • A61H23/0263—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive with rotary motor using rotating unbalanced masses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00452—Skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/02—Characteristics of apparatus not provided for in the preceding codes heated or cooled
    • A61H2201/0207—Characteristics of apparatus not provided for in the preceding codes heated or cooled heated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/02—Characteristics of apparatus not provided for in the preceding codes heated or cooled
    • A61H2201/0214—Characteristics of apparatus not provided for in the preceding codes heated or cooled cooled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/02—Characteristics of apparatus not provided for in the preceding codes heated or cooled
    • A61H2201/0221—Mechanism for heating or cooling
    • A61H2201/0285—Mechanism for heating or cooling with Peltier elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/16—Physical interface with patient
    • A61H2201/1683—Surface of interface
    • A61H2201/1685—Surface of interface interchangeable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/50—Control means thereof
    • A61H2201/5002—Means for controlling a set of similar massage devices acting in sequence at different locations on a patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/50—Control means thereof
    • A61H2201/5023—Interfaces to the user
    • A61H2201/5038—Interfaces to the user freely programmable by the user
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/50—Control means thereof
    • A61H2201/5023—Interfaces to the user
    • A61H2201/5041—Interfaces to the user control is restricted to certain individuals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2230/00—Measuring physical parameters of the user
    • A61H2230/50—Temperature
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36021—External stimulators, e.g. with patch electrodes for treatment of pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662—Visible light
    • A61N2005/0663—Coloured light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0616—Skin treatment other than tanning

Definitions

  • the invention relates to the field of pain abatement systems for injections and minor surgeries and laser treatments, specifically the use of a device employing vibration, tactile, temperature variations, and other stimulus to diminish or abolish patient perception of pain without the use of drugs.
  • the first general category of treatments utilized to relieve injection site pain is that of anesthetic drugs.
  • use of drugs usually limited to local anesthesia.
  • Local anesthetics vary in their pharmacological properties and they are used in various techniques of local anesthesia such as: Topical anesthesia (surface), Plexus block, Infiltration (injection directly into local tissues), Spinal anesthesia (subarachnoid block), and Epidural (extradural) block.
  • Topical anesthetic or analgesic creams applied to the skin represent a widely-used method of local pain perception control.
  • Topical anesthetics are a simple and noninvasive technique involving rubbing a liquid, cream, or gel onto the skin of the patient.
  • Many topical anesthetics including EMLATM, ElamaxTM, liposome-encapsulated lidocaine cream, amethocaine, cetacaine, and benzocaine products, can aid in minimizing the pain of cutaneous procedures including intralesional lidocaine infiltration.
  • This technique can be effective in treating some aspects of injection site pain and the discomfort associated with minor surgeries.
  • the use of these anesthetics can be time consuming and cause occasional complications. This technique provides only limited pain relief and take anywhere from 20 minutes to over an hour to begin to function on the patient.
  • the most common complication of topical anesthesia is contact dermatitis.
  • ElamaxTM which does not contain Patent
  • CAR1.PAU.01 prilocaine may minimize the possibility of contact dermatitis.
  • EMLATM in particular, is associated with extensive corneal deepithelialization, purpura and petechiae and even methemoglobinemia if applied to large areas.
  • Localized pain may be minimized by using cold temperatures applied to the patient's skin.
  • Cold therapy is an effective and non-invasive way to relieve localized pain from injections or minor surgeries. This additionally reduces pain sensation and swelling, and is well known to those familiar with the healing arts.
  • Application of cold reduces nerve sensation by reducing nerve activity through reduction of energy available to the nerve.
  • a simple version of this method involves ice created from frozen water, often wrapped in a thick cloth that is applied to the skin several minutes prior to beginning of the minor procedure.
  • cold therapy may be applied via instant cold packs, or reusable non-toxic gel packs. These are readily available in any pharmacy or supermarket.
  • An additional alternative for minor treatment site pain is the use of 'cold spray', which is the generic name for an aerosol-type spray utilized by clinicians to cool injection sites and therefore minimize pain.
  • the cosmetic laser apparatus can be fitted with a 'cooling head'.
  • a 'cooling head' Several varieties of this type of technology are currently available.
  • One example would be the 'cooling head' on the CoolGlideTM Laser System by Cutera XEO.
  • Another example of this type would be the V Beam® line of cosmetic lasers from Candela Corporation.
  • These technologies are widely used, commercially available, and utilize a fine spray of refrigerant or cryogen onto the skin of the patient at the treatment site.
  • the V Beam ® Perfecta by Candela Corporation uses HFC 34a as a cryogen. This cryogen quickly cools the patient's skin at the treatment area then evaporates.
  • cold therapy must be utilized with some caution. If a cold therapy source is at a low enough temperature, or an excessive amount of cryogen from a cosmetic laser's 'cooling head' is applied, it is possible to cause an ice burn to the area of contact with the patient. Also, some redness on the Patent
  • CAR1.PAU.01 treatment area after treatment with a cold compress is common, but will often vanish shortly.
  • a 'cooling head' is utilized for cosmetic laser treatments, it is of only minor assistance in avoiding dermal burning.
  • many cosmetic laser treatments such as laser dermabrasion, intentionally remove several layers of damaged skin. Such procedures can be highly uncomfortable to patients after treatment, however cold therapy may assist with perceived pain during the treatment, and minimize swelling and discomfort afterwards.
  • Invasive pain management techniques may also be used by the physician. Pain management is invasive when it requires the entry of a needle, catheter, or other instrument into a part of the body. There are a wide range of invasive procedures in order to help minimize the patient's experience of pain, ranging from simple localized infiltration of tissue at a specific site, to general anesthesia techniques. Generally, the wider the analgesic or anesthetic effect, the higher dosage of medication is required, and the greater chance of undesirable side effects. Specifically, the greater amount of anesthetic fluid administered, the lower the border between healthy and distressed tissue becomes. Additionally, for injections into the joints of patients (e.g. a cortisone injection into the spine of a patient to treat chronic back pain), higher quantities of injected fluid are associated with movement of loose or foreign bodies in and around the injection site.
  • a cortisone injection into the spine of a patient to treat chronic back pain higher quantities of injected fluid are associated with movement of loose or foreign bodies in and around the injection site.
  • Infiltration is a mildly invasive administration of anesthesia directly into tissue using a syringe.
  • the tissue becomes anesthetized, however, the anesthetization is extremely localized, and does not help with the pain of deeper injections, such as epidural (extradural) blocks and injections into joint areas.
  • subarachnoid block and epidural (extradural) block
  • epidural block is a general term used to refer to the injection of local anesthetic onto or near nerves for temporary control of pain.
  • Permanent nerve block can be produced by destruction of nerve tissue. It can also be used as a diagnostic tool to identify specific nerves as pain generators. These procedures function under the same basic principle, that of blocking nerve signal transmission at a certain point stops transmission to the Patent
  • CAR1.PAU.01 central nervous system beyond that point. Nerve blocks carry the possibility of side effects and complications from the procedure, needle puncture, and medications used. The most critical factor in the efficacy of a nerve block is the proper location of the target nerve.
  • Complications for a regional nerve block often include infection (often at site of injection, but it can become systemic), allergic reactions to the medication used, and increased pain at the site if the procedure is unsuccessful.
  • nerve blocks are of limited use because of the desire to minimize immediate postoperative disability, and because of the time involved in utilizing the procedure. Postoperative disability is a significant issue, because it limits the ability of a patient to drive home. For example, with the dermatological procedure of administering botulinum type A injection to the hands and feet to reduce normal perspiration, the doctor must commonly limit the procedure to one hand or foot in a single visit. (Kevin C.
  • the clinician could choose to attempt to alter the perception of pain within the patient. This is usually accomplished through talkestheia (talking to the patient, and holding their hand to calm them), or addition of sensory input on or near the area of the minor surgical procedure.
  • the sensory input commonly includes vibration, heat, cold, and tactile input, but may include other types of distractions as well.
  • the current invention functions based upon the gate control theory of pain sensation, which was put forward by Ronald Melzack and Patrick David Wall in 1962 and 1965. This theory holds that the perception of physical pain is not a direct result of activation of nociceptors, but instead is modulated by interaction between different neurons, both pain-transmitting and non-pain- Patent
  • CAR1.PAU.01 transmitting.
  • the theory asserts that activation of nerves that do not transmit pain signals can interfere with signals from pain fibers and inhibit an individual's perception of pain. Therefore, activation of a nerve with a non-noxious stimulus, such as vibration, lessens the perception of the noxious stimulus, such as injection site pain. This is especially the case when non-noxious stimulus can be applied to the same dermatome as is subject to the noxious stimulus.
  • the effect is that the patient is distracted from the pain on both a conscious and biological level. While differing sensations travel along nerve tissue at differing speeds, any sensation can function to limit localized pain response. In clinical use, the most commonly used stimulus include heat, cold, and vibration.
  • the gate control theory of pain is given additional credence based upon current understanding of the speed of transmission of various sensations along sensory fibers in the human body.
  • the Erlanger-Gasser classification of nerve fibers categorizes nerve cells by their function and form.
  • Various nerve types transmit information at drastically varied speeds. For example, Delta sensory fibers transmit pain sensation at an average speed of 15 meters per second, while vibratory sensation is transmitted along Beta sensory fibers at an average speed of 55 meters per second. Utilizing this information, the gate control theory of pain can be utilized to greater effect by applying a non-noxious sensation to the nerve area that is capable of faster transmission than the noxious pain response.
  • Sensory input can be provided to the patient in a great variety of ways to treat minor surgery pain and injection pain.
  • vibrators to add a vibratory sensation around an injection site.
  • the AccuVibe SofttouchTM is a rechargeable personal massager that can be used for vibratory anesthesia.
  • the Hitachi Magic WandTM and the ConAirTM double-headed massager can also be used.
  • medium to large sized vibration units can be overlaid with a sterile surgical glove at the point of contact with the patient.
  • Other devices such as the Vibrating Fingertip Massager can be worn on a clinician's hand and provide a small point Patent
  • CAR1.PAU.01 of contact with the patient's skin can be covered with disposable finger cots from a provider such as Henry Schein, Inc.
  • Hot pack gel packs are available from any sporting goods supply or the local drug store. Cold compresses can be
  • Vibration anesthesia is taught by Kevin C. Smith, MD, et al. in Vibration anesthesia: A noninvasive method of reducing discomfort prior to dermatologic procedures.
  • Palmesano, et al. in Effect of High-Frequency Vibration on Experimental Pain Threshold in Young Women When Applied to Areas of Different Size (The Clinical Journal of Pain, Vol. 5, pp337-342, 1989).
  • the use of certain vibrations per minute to maximize therapeutic value is taught, and generally falls into the range of 50 Hz to 150Hz.
  • a further study of this is done by E. Nanitsos et al. in The effect of vibration on pain during local anesthesia injections (Australian Dental Journal, Vol. 54, pp 94-100, 2009) regarding Novocain injections before dental work can be performed.
  • Treatment with cold generally includes holding a cold object (such as an ice cube) on the injection site for 30 seconds to a minute before the injection, then holding the cold object in close vicinity to the injection site during the injection. Significant reduction in pain can be accomplished with this technique.
  • a cold object such as an ice cube
  • Buzzy Pain Management www.needle-pain-management.com
  • Buzzy Pain Management utilizes a small vibrating device and either a disposable water-filled cold pack, or a re- freezable cold pack. While this device may be able to provide relief for injection site pain, it does not teach a way to heat the site of the minor surgery, it does not allow vibration in waves near the site of injection, and the cold pack must be kept in a freezer before use. Further, there is no way to adjust or measure the temperature of the cold pack.
  • the limitations of the above noted prior art are surmounted by the illustrated embodiments of the invention presented here.
  • the illustrated embodiments of the invention teach the use of a plurality of sensory inputs to minimize the perception of pain associated with minor invasive procedures and laser treatment therapies.
  • Various sensory inputs may be utilized simultaneously for maximum effect for that individual patient.
  • Previous sensory input techniques include: use of temperature, including heat and cold by way of a Peltier element which allows for temperature fluctuation between hot and cold; tactile input, by way of various surface textures to the 'head' which acts as the point of contact with the patient by way of the various sterile head covers for the device; and vibration by utilizing multiple small vibratory motors, allowing for selection of various 'wave' and 'pulse' sensations for the patient.
  • the illustrated embodiments of the invention include a portable, hand held device that applies a temperature controlled surface, tactile input, and vibration to a patient's skin for the purpose of minimizing pain perception.
  • a form-fitted housing allows for easy grip by the clinician. Controls are simple to understand, and retain the settings from the previous use, so that a clinician may utilize the device with their favorite Patent
  • CAR1.PAU.01 configuration repeatedly with the touch of one button.
  • the clinician can rely upon the built-in direct current rechargeable power source, or plug the unit into a wall outlet for easy continuous use. Finally, the clinician need not worry about the device becoming damaged or overheated when struck by the beam in
  • Heating and cooling at tip of the device is accomplished by the thermoelectric principle using the Peltier effect to create a heat flux between two different types of materials usually constructed with solid-state materials.
  • This solid-state active heat pump has no moving parts and transfers heat from one side of the device to the other side against the temperature gradient (from cold to hot), with consumption of electrical energy.
  • the head contains the Peltier element, which is capable of pumping heat in one direction or another depending on the direction of the current applied to the element.
  • the active side With one side of the element held at room temperature (25-30 °C) by using an integrated heat sink on the head, the active side can be heated or cooled by temperature difference ⁇ . This is done by supplying current across the Peltier element.
  • the maximum temperature difference between the faces between the Peltier plates is set by a microcontroller to 30 °C to prevent burns on the skin.
  • ATmax The maximum temperature difference between the faces between the Peltier plates
  • the device can heat or cool by moving about 1.5 Watt (15% efficiency) of heat across its surface, enough to momentarily provide hot/cold sensation.
  • thermoelectric cooling and heating system for example a Peltier thermoelectric device.
  • the device utilizes a variety of vibratory modes, selectable by the clinician, in order to provide the most effective treatment to an individualized patient.
  • the device may utilize a plurality of vibration head attachments. These are designed to come in various shapes and sizes.
  • the shapes and sizes of the device heads allow access to the many contours of the human body, letting the physician to utilize the device at any site where injection or cosmetic laser treatments may be administered.
  • the device including vibration, temperature, and tactile stimulus head
  • attachments and the handle body of the device be constructed from materials that allow for the equipment to maintain a temperature range that is not damaging to the skin while being struck with the laser light beam from cosmetic laser device. Further, the materials selected enable the illustrated embodiments of the invention to be highly tolerant to being exposed to the laser beam of cosmetic laser devices, which allows for longevity of the useful life of the device and its components.
  • these said disposable sterile coverings be made with a variety of surface textures, providing for a variety of tactile input sensations to the patient.
  • the illustrated embodiments include a hand held device for providing pain abatement during medical procedures or non-ocular laser treatments.
  • the device comprises a handle, a removable controllable vibration head coupled to the distal end of the handle to selectively generate
  • thermoelectric pad disposed on the removable vibration head to selectively generate thermal energy
  • LCD display disposed within the handle coupled to the vibration head to display at least one parameter of the vibrational energy generated by the vibration head and coupled to the thermoelectric pad to display at least one parameter of thermal energy generated by the thermoelectric pad
  • power supply coupled to the vibration head, thermoelectric pad, and LCD display and disposed within the proximal end of the handle.
  • the vibration head and thermoelectric pad are controlled in a
  • the removable vibration head includes in one embodiment a U- shaped vibration head including a plurality of eccentric weight motors.
  • the removable vibration head includes in one embodiment a solid vibration head including a plurality of coin-type motors.
  • the device further includes a vibration control switch for selecting one of a plurality of predetermined vibrational frequencies at which the
  • the device includes a vibration control switch for selecting a vibrational frequency at which the removable vibration head operates within a frequency range of 0 Hz to at least 250 Hz.
  • the device further includes in one embodiment a microcontroller disposed within the handle, wherein the microcontroller controls the vibrational frequency of the removable vibration head and the temperature of the
  • thermoelectric pad according to the teachings of the illustrated embodiments of the invention.
  • the microcontroller controls the temperature of the thermoelectric pad between a minimum and a maximum threshold temperature.
  • the microcontroller controls the vibrational frequency at which the removable Patent
  • CAR1 .PAU.01 vibration head operates to create waves of vibration or synchronized vibration among the plurality of vibration motors.
  • the display shows the temperature of a patient's skin at the treatment site in real-time.
  • the power supply includes in one embodiment a charging connector disposed in the proximal end of the handle.
  • the charging connector is inserted or connected into and electrically coupled with the charging dock, or the charging connector disposed in the proximal end of the handle may be
  • the power supply includes in one embodiment a plurality of rechargeable batteries disposed within the handle.
  • the illustrated embodiments of the invention include within their scope a method for abating pain in or on the skin during medical procedures or non-ocular laser treatments using a hand held device comprising the steps of selecting a predetermined vibration setting of a removable vibration head coupled to the distal end of a handle of the device by means disposed on the handle of the device, selecting a corresponding predetermined temperature setting of the removable vibration head by means disposed on the handle of the device, positioning the removable vibration head against the skin of a patient adjacent to a treatment site, and stimulating the skin of the patient with heat and/or vibration at or adjacent to the treatment site while performing the medical procedure or non-ocular laser treatment at the treatment site.
  • the setting of the vibration and temperature to predetermined values is determined experientially depending on the perception of the patient, and the nature and location of the pain which is sought to be abated.
  • the illustrated embodiments of the method further include, prior to positioning the removable vibration head against the skin at the, treatment site, the step of selecting one of a plurality of removable vibration heads according to the specific contour of the patient's skin to undergo treatment and coupling the selected head to the distal end of the handle of the device.
  • the step of selecting the temperature setting of the removable vibration head by means disposed on the handle of the device includes in one embodiment the step of selecting the temperature setting of a Peltier
  • thermoelectric pad disposed on the removable vibration head.
  • the illustrated embodiments of the method further include the step of maintaining the temperature of the removable vibration head between a predetermined minimum and maximum threshold temperature.
  • the illustrated embodiments of the method further include the step of displaying the temperature of the patient's skin adjacent to the treatment site on an LCD display disposed within the handle of the device.
  • the illustrated embodiments of the method further include the step of supplying power to the device from an outside power source via a power cord.
  • the illustrated embodiments of the method further include the step of supplying power to the device from a plurality of rechargeable batteries.
  • the illustrated embodiments of the method further include the step of recharging the plurality of rechargeable batteries by coupling the handle of the device with a charging dock which is electrically coupled to the plurality of rechargeable batteries.
  • Fig. 1 is a depiction of one use of the pain abatement stimulus device where the hand of a clinician is shown holding the device against the patient's shoulder in preparation for an inoculation.
  • FIG. 2 is a magnified view of the left side of the device seen in Fig. 1 showing an LCD screen, a power button, a plurality temperature control buttons, and a vibratory control button.
  • Fig. 3 is a partial cut-away view of the inside of the device seen in Fig. 2 showing the internal components and a U-shaped vibratory temperature control head.
  • Fig. 4 is a magnified view of the controls of the device seen in Fig. 2 with an alternative circular embodiment for the control head. The coupling between the removable control head and the body of the device is shown.
  • Fig. 5a is a magnified view of the circular head sensory input seen in Fig. 4 including the small vibration units disposed within the control head.
  • Fig. 5b is a magnified view of the detached and replaceable U- shaped vibration head seen in Fig. 3 including the soft heating and cooling pad disposed on the head.
  • Fig. 5c is a magnified view of an alternative embodiment of the control head comprising a detachable and replaceable solid vibration head including the soft heating and cooling pad disposed on the head.
  • Fig. 6 is a schematic diagram depicting the LCD screen and temperature control circuitry logic.
  • Fig. 1 depicts a clinician's hand 10 administering treatment utilizing the pain abatement stimulation device 1 , herein after referred to as "device", on the shoulder 11 of a patient.
  • the patient receives stimulus from the device 1 at a region of interaction 12 between the patient and the device 1.
  • the positioning of the device 1 seen in Fig. 1 would be common for intramuscular inoculations administered to children and is meant to be for illustrative purposes only. It is to be expressly understood that the device 1 may be used at other regions of interaction 12 anywhere else on the body of the patient without departing from the original spirit and scope of the invention.
  • the device 1 comprises a handle 300 comprising a housing 302 as seen in Fig. 2 that is comprised of easily gripped, slip resistant material that allows the clinician 10 to use the device 1 while wearing sterile medical gloves.
  • a handle 300 comprising a housing 302 as seen in Fig. 2 that is comprised of easily gripped, slip resistant material that allows the clinician 10 to use the device 1 while wearing sterile medical gloves.
  • An example of this material would be an injection molded plastic with a
  • the device 1 comprises an ergonomic portion 301 which assures a reliable grip and allows the clinician to apply pressure to a point of contact on the patient's skin.
  • An on/off button 203 allows for easy manipulation of the power of the unit with one simple thumb press and is made of a non-slip material such as plastic or rubber as is known in the art.
  • a plurality of temperature control buttons 202 for temperature adjustment are located on the 'neck' of the housing 302, out of the reach of the ergonomic portion 301 , yet still easily reachable by the clinician. This configuration minimizes accidental temperature control changes.
  • a vibration control switch 201 sets the device to output to approximately 50 Hz, 100Hz, or 150Hz, as determined by the clinician and based upon the patient's comfort levels.
  • the specific vibrational intensities listed above are meant to be for illustrative purposes only. Other rates of vibration may be used without falling outside the scope of this invention.
  • a stimulus head connector 101 which couples a head 100 to the distal end of the body 302 is shown in Figs. 2, 4, and 5b.
  • the stimulus head connector 101 comprises multiple pin connections enabling electrical flow and control of the various functions of the replaceable and removable vibration heads 100, 1 10.
  • Fig. 2 depicts a replaceable U-shaped vibration head 100, the handle 300, and a charging dock 400.
  • the combination of the handle 300 and charging dock 400 as seen in Fig. 2 is representative of how the device would stand on a surface in an examining room of a clinician's office.
  • the vibration control switch 201 allows the clinician control over the vibration.
  • the vibration control switch's 201 easy access allows the clinician to adjust this setting to the needs of their patients swiftly and easily.
  • the temperature control buttons 202 are equally accessible to the clinician, facilitating delicate temperature controls when needed.
  • the master on/off button 203 is positioned so that the clinician's thumb can reach it without loosening or changing grip on the ergonomic portion 301 defined within the housing 302.
  • the housing 302 encloses the electronics, controls, and displays in a robust shell.
  • the liquid crystal display 204 displays information critical to the treatment of the patient, such as the current
  • the underside of the housing 302, as best seen in Fig. 3, shows the location of a charging dock connector 401 at the distal end of the handle 300.
  • the charging dock connector 401 is preferably coupled to the charging dock 400 through a magnetic connection, such as MagSafeTM by Apple, Inc., allowing for easy breakaway as an additional safety factor, while providing a secure power connection should the power chord be necessary.
  • Other power connections such as standard physical force-fit plastic connections may be utilized and fall within the original vision and scope of the invention.
  • the device 1 relies upon a battery power supply 402, 403 to provide cordless power. Shown in Fig. 3 are two standard NiMH rechargeable C sized batteries. However, should additional cordless power be needed, a higher weight/size to power ratio battery chemistry, such as Lithium Polymer, can be utilized.
  • CAR1.PAU.01 couples to the charging dock 400 which is in turn coupled to an AC wall outlet which provides the power required to charge the batteries 402, 403.
  • the same charging connector 401 can be coupled to a power chord (not seen) for use extended beyond the life of the batteries 402, 403.
  • Fig. 3 further shows the internal components of the replaceable U- shaped vibration head 100.
  • a plurality of micro-vibration motors 102, 103, 104, 105 with eccentric weights can be seen.
  • the vibration head 100 can offer its own vibration strength and sequence, providing sensations of bursts or waves of vibration to the patient.
  • Fig. 3 also shows an embodiment of the placement of a printed circuit board (PCB) 500 that acts as a controller for the device 1.
  • the control PCB 500 regulates the input and output, and comprises means for recalling previous settings chosen by the clinician to facilitate use of the device 1.
  • Fig. 4 is a representation of an alternative embodiment of device 1 with handle 300 being coupled with a replaceable solid vibration head 110.
  • the solid vibration head 110 is substantially disk shaped and comprises a
  • Fig. 3 also highlights the functioning of the stimulus head connector 101 to the handle 300, showing the curved nestled insert with electrical pin connectors for power and sensor data flow.
  • Fig. 5a shows the embodiment of the replaceable solid vibration head 110.
  • a plurality of at least four micro-vibration coin-type motors 112, 113, 1 14, 115 are shown within the solid vibration head 1 10 which provide vibratory stimulus to the patient.
  • a great variety of stimulus options are made available by using different heads.
  • Fig. 5b shows the replaceable U-shaped vibration head 100 and highlights the stimulus head connector 101 which is coupled to the handle 300 of the device 1.
  • the U-shaped vibration head 100 comprises a correspondingly Patent
  • CAR1.PAU.01 shaped Peltier thermoelectric pad 111 with a soft covering which provides heat and cold sensation to the patient's skin.
  • Fig. 5c is a magnified view of the replaceable solid vibration head 110.
  • the stimulus head connector 101 which is coupled to the handle 300 of the device 1 is shown again.
  • the Peltier thermoelectric pad 1 1 1 with soft covering corresponding with the shape of the solid vibration head 110 is shown, which provides heat and cold sensation to the patient's skin.
  • Fig. 6 depicts a microcontroller 501 and its supporting devices that are disposed upon the control PCB 500.
  • the microcontroller 501 is enabled with a variety of temperature adjustment settings, including the important safety feature of a maximum and minimum allowable threshold temperature of the device 1.
  • the control PCB 500 acts as an intermediary device between all controlling components seen in Fig. 6.
  • a temperature sensor 51 1 coupled to the microcontroller 501 senses the temperature at the point of contact of that particular vibration head for example the U-shaped vibration head 100 seen in Fig. 5b or the solid vibration head 1 10 seen in Fig. 5c.
  • the microcontroller 501 automatically adjusts the temperature of the device 1 based upon the
  • the temperature settings of the vibration head 100, 110 default to standards where there is no cover, thereby assuring that the patient is not injured or burned by the device 1 , as the cover would add thickness and reduce thermal conductivity under normal circumstances.
  • the LCD 204 is capable of displaying the actual temperature at the point of contact of the vibration head 100, 110 with the patient's skin, or the temperature as adjusted to compensate for the sterile cover, or both.
  • a voltage regulator 502 coupled to the microcontroller 501 controls the voltage output to the other aspects of the device and acts as a secondary safety system by limiting the electronic energy shunted to the Peltier thermoelectric element 11 1 and vibration motors 112-1 15, 102-105 to safe levels.
  • the microcontroller 501 provides exact control over the Peltier thermoelectric heating control 521 and cooling control 522.
  • the microcontroller 501 also provides control over the vibration motors Patent
  • a control for vibration intensity 201 and control button for temperature adjustment 202 which will instruct the microcontroller 501 to heat or cool the vibration head 100, 110 according to the clinician's desired settings.
  • the following example represents one embodiment of the temperature control programming contained within the microcontroller 501 of the current device 1.
  • the example presented below in pseudocode provides for the necessary safety parameter by setting a maximum and minimum temperature thresholds. This example is meant for demonstrative purposes only, and should not be construed to encapsulate the complete embodiment of this invention.
  • VibeMode ⁇ Off, Patternl , Pattern2 PatternN ⁇
  • the vibration heads 100, 110 as exemplified in Fig. 5b and 5c, show only two examples of the plurality of types of heads that can be attached to the handle 300 of the device 1.
  • the heads will come in a variety of shapes and sizes to suit the gamut of surfaces of the human body. This will allow the device to be utilized wherever an injection or minor surgical procedure is to occur.
  • the vibration head 100, 110 utilizes a soft heating and cooling pad 111 to provide comfort to the patient, while also applying the local topical temperature needed for pain abatement
  • the device 1 including the handle 300 and vibration heads 100, 110, are protected from damage and undue heat absorption Patent
  • the shielding utilized may include ceramic plating and other shielding compositions such as those well known to those in the art.
  • the device 1 may comprise a plurality of shielding techniques or types in order to protect the device 1 against the wide range of wavelengths, powers, and durations utilized for various laser treatment techniques.
  • the vibration control switch 201 utilizes a fully adjustable setting such as a dial or slidable aperture, allowing any vibration cycle that the clinician chooses ranging between no vibration and a very high vibration, for example 250Hz or more.
  • the neck of the handle 300 comprises a lockable hinge, allowing an adjustable alteration to the orientation of the vibration heads coupled to the device 1.
  • the plurality of vibration heads may utilize synchronized and fully controllable vibration functions for each of the plurality of micro vibration motors such as eccentric weight motors 102-105, exemplified in Fig. 3, or micro vibration coin-type motors 1 12-115, exemplified in Fig. 5b.
  • Independently controlled vibration motors allow for a greater range of vibratory sensations to the patient, including a 'wave' like vibration of the treatment site, allowing the patient's sensory input to vary over the course of the treatment to maximize noxious sensory block via the gate control theory of pain.
  • the plurality of vibration heads 100, 110 comprise a separate heating and cooling element, both of which are of solid state construction.
  • a standard metal resistance heating element may be used as is known in the art. This configuration allows for novel non-invasive treatment options. For example, by quickly switching between hot and cold, the patient is Patent
  • CAR1.PAU.01 able to experience sensatory anesthesia. It further allows for a use of a plurality of sensory outputs to a patient to alleviate the pain of minor surgical procedures, injections, and non-ocular laser treatments. This would be applicable to any minor surgical procedure or injection. Examples of this would be, but are not limited to: dermatological procedures involving injection (i.e. BotoxTM,
  • the device 1 is designed for use in minor surgical procedures, injections, non-ocular laser treatments, and cosmetic laser treatments. During certain procedures where vibration of the patient is not optimal (e.g. ocular laser surgery), the vibration settings of this device 1 are not to be used, or a negative outcome of the procedure will likely result.
  • the charging dock 400 will remain plugged into an AC wall outlet power source at all times.
  • the handle 300 of the device 1 is nested into the charging dock 400 in order to maintain full charge for the rechargeable batteries 402, 403 of the device 1. This maximizes the cordless use of the device 1 when it is desired.
  • the clinician will lift the handle 300 out of the charging dock 400, select the proper vibration head, for example the replaceable U-shaped vibration head 100, and fit it with a sterile barrier device (not shown) to protect the patient from infection.
  • the clinician will choose the vibration and temperature settings as deemed appropriate for the patient receiving treatment utilizing the corresponding switches 201 , 202 disposed on the handle 300.
  • the clinician will then manually position the vibration head 100 at the appropriate location on the patient, which will usually be adjacent to the treatment site.
  • Stimulus may also be applied to other locations, such as on the same nerve where discomfort will be experienced by the patient, but with a shorter distance to the spinal column than from the operation site.
  • CAR1.PAU.01 placement of the stimulus will be determined by the clinician, who will be able to utilize feedback from the patient for proper placement and settings choice.
  • the handle 300 may be directly plugged into an AC wall power outlet via a chord connected to the charging connector 401 disposed in the proximal end of the handle 300.
  • the batteries 402, 403 may be replaced with a new fully charged set of batteries.
  • CAR1 .PAU.01 defined meanings. Thus if an element can be understood in the context of this specification as including more than one meaning, then its use in a claim must be understood as being generic to all possible meanings supported by the specification and by the word itself.
  • combination may be directed to a subcombination or variation of a

Abstract

La présente invention concerne un dispositif de diminution de la douleur faisant appel à des entrées sensorielles telles qu'un mouvement vibratoire, une sensation tactile, de la chaleur, et du froid pour affronter le signal de douleur nocif et pour diminuer une douleur au site d'injection, une douleur associée à des chirurgies mineures, et une douleur associée à des traitements au laser non oculaires. Le dispositif est conçu pour résister à la chaleur transférée par des faisceaux laser de traitement chirurgical, et pour empêcher le dispositif d'être endommagé par ledit laser. Plusieurs accessoires de tête vibrante permettent d'utiliser le dispositif sur n'importe quel contour du corps humain. Les accessoires de tête vibrante comprennent un dispositif thermoélectrique Peltier pour transmettre la chaleur ou le froid sur la peau du patient, en fonction du réglage de température choisi par le clinicien. Chaque accessoire parmi la pluralité d'accessoires de tête profite d'un couvercle jetable stérile en silicone ou en plastique correspondant doté de diverses textures superficielles, ce qui fournit un point de contact stérile avec le patient et une stimulation additionnelle du système nerveux.
PCT/US2010/039234 2010-06-18 2010-06-18 Procédé et appareil pour stimulus vibratoire, tactile et autre localisé pour diminuer la douleur associée à des injections pour des procédures chirurgicales mineures et des traitements cosmétiques au laser WO2011159317A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/US2010/039234 WO2011159317A1 (fr) 2010-06-18 2010-06-18 Procédé et appareil pour stimulus vibratoire, tactile et autre localisé pour diminuer la douleur associée à des injections pour des procédures chirurgicales mineures et des traitements cosmétiques au laser

Applications Claiming Priority (1)

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PCT/US2010/039234 WO2011159317A1 (fr) 2010-06-18 2010-06-18 Procédé et appareil pour stimulus vibratoire, tactile et autre localisé pour diminuer la douleur associée à des injections pour des procédures chirurgicales mineures et des traitements cosmétiques au laser

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Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103279156A (zh) * 2013-05-20 2013-09-04 东南大学 可持续感知的温度复现方法及装置
CN109260005A (zh) * 2018-10-11 2019-01-25 北京航空航天大学 多功能复合治疗装置
WO2019165433A1 (fr) 2018-02-26 2019-08-29 Olympic Ophthalmics, Inc. Dispositif portatif doté d'un élément vibratoire pour le traitement de troubles
WO2020032980A1 (fr) * 2018-08-10 2020-02-13 Rezzimax, LLC Dispositif de prise en charge de la douleur
WO2020245466A1 (fr) 2019-06-07 2020-12-10 Syndermix Ag Dispositif mécanique de thérapie énergétique
WO2020245467A1 (fr) 2019-06-07 2020-12-10 Syndermix Ag Générateur de vibrations
WO2021222346A1 (fr) * 2020-04-30 2021-11-04 L'oreal Système permettant l'administration d'une luminothérapie en même temps que l'augmentation du seuil de douleur avec un stimulus de distraction
FR3111564A1 (fr) * 2020-06-23 2021-12-24 L'oreal Systemes et procedes d’administration de luminotherapie tout en augmentant le seuil de douleur avec un stimulus de distraction
US11235167B2 (en) 2020-04-30 2022-02-01 L'oreal Systems and methods for administering light therapy while increasing pain threshold with distraction stimulus
US11357697B2 (en) 2018-12-26 2022-06-14 Therabody, Inc. Percussive therapy device
EP4248898A1 (fr) * 2022-03-25 2023-09-27 Cutera Inc. Systèmes de commande de traitement laser thérapeutique sur la base d'un rapport de refroidissement sur chauffage
US11813221B2 (en) 2019-05-07 2023-11-14 Therabody, Inc. Portable percussive massage device
US11857481B2 (en) 2022-02-28 2024-01-02 Therabody, Inc. System for electrical connection of massage attachment to percussive therapy device
US11890253B2 (en) 2018-12-26 2024-02-06 Therabody, Inc. Percussive therapy device with interchangeable modules
US11957635B2 (en) 2015-06-20 2024-04-16 Therabody, Inc. Percussive therapy device with variable amplitude

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WO2006034324A2 (fr) * 2004-09-20 2006-03-30 Goldberg Steven G Dispositif et procede permettant de reduire la douleur durant les operations de percement de la peau
US20060211961A1 (en) * 2005-03-18 2006-09-21 Meyer Elizabeth H Massager with shock absorption, multiple contact surfaces and visual therapy effects
WO2008113139A1 (fr) * 2007-03-21 2008-09-25 Cypro-Ssage Pty Ltd Dispositif de massage

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Publication number Priority date Publication date Assignee Title
US20040171970A1 (en) * 2001-03-29 2004-09-02 Kurt Schleuniger Hand-held device for pain relief
WO2006034324A2 (fr) * 2004-09-20 2006-03-30 Goldberg Steven G Dispositif et procede permettant de reduire la douleur durant les operations de percement de la peau
US20060211961A1 (en) * 2005-03-18 2006-09-21 Meyer Elizabeth H Massager with shock absorption, multiple contact surfaces and visual therapy effects
WO2008113139A1 (fr) * 2007-03-21 2008-09-25 Cypro-Ssage Pty Ltd Dispositif de massage

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103279156A (zh) * 2013-05-20 2013-09-04 东南大学 可持续感知的温度复现方法及装置
US11957635B2 (en) 2015-06-20 2024-04-16 Therabody, Inc. Percussive therapy device with variable amplitude
EP3758664A4 (fr) * 2018-02-26 2022-04-06 Olympic Ophthalmics, Inc. Dispositif portatif doté d'un élément vibratoire pour le traitement de troubles
WO2019165433A1 (fr) 2018-02-26 2019-08-29 Olympic Ophthalmics, Inc. Dispositif portatif doté d'un élément vibratoire pour le traitement de troubles
WO2020032980A1 (fr) * 2018-08-10 2020-02-13 Rezzimax, LLC Dispositif de prise en charge de la douleur
CN109260005A (zh) * 2018-10-11 2019-01-25 北京航空航天大学 多功能复合治疗装置
US11890253B2 (en) 2018-12-26 2024-02-06 Therabody, Inc. Percussive therapy device with interchangeable modules
US11357697B2 (en) 2018-12-26 2022-06-14 Therabody, Inc. Percussive therapy device
US11813221B2 (en) 2019-05-07 2023-11-14 Therabody, Inc. Portable percussive massage device
WO2020245466A1 (fr) 2019-06-07 2020-12-10 Syndermix Ag Dispositif mécanique de thérapie énergétique
WO2020245467A1 (fr) 2019-06-07 2020-12-10 Syndermix Ag Générateur de vibrations
US11235167B2 (en) 2020-04-30 2022-02-01 L'oreal Systems and methods for administering light therapy while increasing pain threshold with distraction stimulus
WO2021222346A1 (fr) * 2020-04-30 2021-11-04 L'oreal Système permettant l'administration d'une luminothérapie en même temps que l'augmentation du seuil de douleur avec un stimulus de distraction
FR3111564A1 (fr) * 2020-06-23 2021-12-24 L'oreal Systemes et procedes d’administration de luminotherapie tout en augmentant le seuil de douleur avec un stimulus de distraction
US11857481B2 (en) 2022-02-28 2024-01-02 Therabody, Inc. System for electrical connection of massage attachment to percussive therapy device
EP4248898A1 (fr) * 2022-03-25 2023-09-27 Cutera Inc. Systèmes de commande de traitement laser thérapeutique sur la base d'un rapport de refroidissement sur chauffage

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