WO2011146498A3 - Configurable pulse generator - Google Patents

Configurable pulse generator Download PDF

Info

Publication number
WO2011146498A3
WO2011146498A3 PCT/US2011/036828 US2011036828W WO2011146498A3 WO 2011146498 A3 WO2011146498 A3 WO 2011146498A3 US 2011036828 W US2011036828 W US 2011036828W WO 2011146498 A3 WO2011146498 A3 WO 2011146498A3
Authority
WO
WIPO (PCT)
Prior art keywords
pulse generator
pulses
load
generate
configurable pulse
Prior art date
Application number
PCT/US2011/036828
Other languages
French (fr)
Other versions
WO2011146498A2 (en
Inventor
Alon Deutsch
Jonathan Hares
Shlomo Azar
Avi Livnat
Original Assignee
Rafael Development Corporation, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rafael Development Corporation, Ltd. filed Critical Rafael Development Corporation, Ltd.
Publication of WO2011146498A2 publication Critical patent/WO2011146498A2/en
Publication of WO2011146498A3 publication Critical patent/WO2011146498A3/en

Links

Classifications

    • H—ELECTRICITY
    • H03—ELECTRONIC CIRCUITRY
    • H03K—PULSE TECHNIQUE
    • H03K3/00—Circuits for generating electric pulses; Monostable, bistable or multistable circuits
    • H03K3/02—Generators characterised by the type of circuit or by the means used for producing pulses
    • H03K3/53—Generators characterised by the type of circuit or by the means used for producing pulses by the use of an energy-accumulating element discharged through the load by a switching device controlled by an external signal and not incorporating positive feedback
    • H03K3/57—Generators characterised by the type of circuit or by the means used for producing pulses by the use of an energy-accumulating element discharged through the load by a switching device controlled by an external signal and not incorporating positive feedback the switching device being a semiconductor device
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39—Heart defibrillators
    • A61N1/3975—Power supply
    • A61N1/3981—High voltage charging circuitry
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02M—APPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC, OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWER SUPPLY SYSTEMS; CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUT POWER; CONTROL OR REGULATION THEREOF
    • H02M3/00—Conversion of dc power input into dc power output
    • H02M3/02—Conversion of dc power input into dc power output without intermediate conversion into ac
    • H02M3/04—Conversion of dc power input into dc power output without intermediate conversion into ac by static converters
    • H02M3/06—Conversion of dc power input into dc power output without intermediate conversion into ac by static converters using resistors or capacitors, e.g. potential divider
    • H02M3/07—Conversion of dc power input into dc power output without intermediate conversion into ac by static converters using resistors or capacitors, e.g. potential divider using capacitors charged and discharged alternately by semiconductor devices with control electrode, e.g. charge pumps

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Power Engineering (AREA)
  • Electrotherapy Devices (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

Disclosed are devices, systems, and methods, including a device that includes a dynamically configurable pulse generator to generate one or more electrical pulses with one or more adjustable attributes, the one or more pulses to be applied to a load (e.g., cardiac tissue) through electrodes. The configurable pulse generator is operable to be reconfigured after generating at least one of the one or more pulses. The device also includes a controller to dynamically configure the pulse generator to generate the one or more electrical pulses. The device may further include at least one sensor to measure at least one characteristic (e.g., impedance) associated with the load (e.g., the cardiac tissue of a patient). The pulse generator may be adapted to generate the one or more pulses with the attributes determined based, at least in part, on the measured at least one characteristic associated with the load.
PCT/US2011/036828 2010-05-17 2011-05-17 Configurable pulse generator WO2011146498A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39558810P 2010-05-17 2010-05-17
US61/395,588 2010-05-17

Publications (2)

Publication Number Publication Date
WO2011146498A2 WO2011146498A2 (en) 2011-11-24
WO2011146498A3 true WO2011146498A3 (en) 2012-03-15

Family

ID=44992291

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/036828 WO2011146498A2 (en) 2010-05-17 2011-05-17 Configurable pulse generator

Country Status (1)

Country Link
WO (1) WO2011146498A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102545687A (en) 2011-12-31 2012-07-04 同方威视技术股份有限公司 Device and method for outputting voltage alternative pulses
US10905884B2 (en) 2012-07-20 2021-02-02 Cardialen, Inc. Multi-stage atrial cardioversion therapy leads
US10080891B2 (en) * 2015-12-03 2018-09-25 Medtronic, Inc. Extra-cardiovascular cardiac pacing system
US10548665B2 (en) 2016-02-29 2020-02-04 Pulse Biosciences, Inc. High-voltage analog circuit pulser with feedback control
US10874451B2 (en) 2016-02-29 2020-12-29 Pulse Biosciences, Inc. High-voltage analog circuit pulser and pulse generator discharge circuit
EP3457976A4 (en) 2016-05-16 2019-12-11 Pulse Biosciences, Inc. Pulse applicator
US10543357B2 (en) 2016-09-19 2020-01-28 Pulse Biosciences, Inc. High voltage connectors for pulse generators
RU2636108C1 (en) * 2017-02-14 2017-11-20 Михаил Владимирович Ефанов High-voltage pulse generator
US10946193B2 (en) 2017-02-28 2021-03-16 Pulse Biosciences, Inc. Pulse generator with independent panel triggering
US10855262B2 (en) 2017-06-19 2020-12-01 Stangenes Industries, Inc. Systems and method for paralleled identical marx generators
WO2019036549A1 (en) 2017-08-16 2019-02-21 Old Dominion University Research Foundation Targeted remote electrostimulation by interference of bipolar nanosecond pulses
US10857347B2 (en) 2017-09-19 2020-12-08 Pulse Biosciences, Inc. Treatment instrument and high-voltage connectors for robotic surgical system
KR102556144B1 (en) 2018-11-08 2023-07-14 올드 도미니언 유니버시티 리서치 파운데이션 Megahertz compression of nanosecond pulse bursts
US11571569B2 (en) 2019-02-15 2023-02-07 Pulse Biosciences, Inc. High-voltage catheters for sub-microsecond pulsing
EP4147656A1 (en) * 2021-09-14 2023-03-15 Erbe Elektromedizin GmbH Generator and method for generating a treatment voltage

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050267545A1 (en) * 2004-05-25 2005-12-01 Nervonix, Inc. Nerve stimulator and method
WO2008010220A2 (en) * 2006-07-17 2008-01-24 A. I. Medical Semiconductor Intelligent control system for adaptive cardiac resynchronization therapy device
EP1882493A2 (en) * 2006-07-25 2008-01-30 BIOTRONIK CRM Patent AG Cardiac pacemaker
US20090210025A1 (en) * 2008-02-19 2009-08-20 Masoud Ameri Model reference identification and cancellation of magnetically-induced voltages in a gradient magnetic field

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050267545A1 (en) * 2004-05-25 2005-12-01 Nervonix, Inc. Nerve stimulator and method
WO2008010220A2 (en) * 2006-07-17 2008-01-24 A. I. Medical Semiconductor Intelligent control system for adaptive cardiac resynchronization therapy device
EP1882493A2 (en) * 2006-07-25 2008-01-30 BIOTRONIK CRM Patent AG Cardiac pacemaker
US20090210025A1 (en) * 2008-02-19 2009-08-20 Masoud Ameri Model reference identification and cancellation of magnetically-induced voltages in a gradient magnetic field

Also Published As

Publication number Publication date
WO2011146498A2 (en) 2011-11-24

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