WO2011145108A3 - Purification of capsular polysaccharides - Google Patents

Purification of capsular polysaccharides Download PDF

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Publication number
WO2011145108A3
WO2011145108A3 PCT/IN2011/000332 IN2011000332W WO2011145108A3 WO 2011145108 A3 WO2011145108 A3 WO 2011145108A3 IN 2011000332 W IN2011000332 W IN 2011000332W WO 2011145108 A3 WO2011145108 A3 WO 2011145108A3
Authority
WO
WIPO (PCT)
Prior art keywords
purification
capsular polysaccharides
removal
reduction
capsular polysaccharide
Prior art date
Application number
PCT/IN2011/000332
Other languages
French (fr)
Other versions
WO2011145108A2 (en
Inventor
Subhash Vinayak Kapre
Swapan Kumar Jana
Original Assignee
Serum Institute Of India Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Serum Institute Of India Ltd. filed Critical Serum Institute Of India Ltd.
Publication of WO2011145108A2 publication Critical patent/WO2011145108A2/en
Publication of WO2011145108A3 publication Critical patent/WO2011145108A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

A method for reduction or removal of protein impurities from a complex cellular bacterial lysate and purification of capsular polysaccharide thereof.
PCT/IN2011/000332 2010-05-15 2011-05-12 Purification of capsular polysaccharides WO2011145108A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1572MU2010 2010-05-15
IN1572/MUM/2010 2010-05-15

Publications (2)

Publication Number Publication Date
WO2011145108A2 WO2011145108A2 (en) 2011-11-24
WO2011145108A3 true WO2011145108A3 (en) 2012-02-02

Family

ID=44992151

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2011/000332 WO2011145108A2 (en) 2010-05-15 2011-05-12 Purification of capsular polysaccharides

Country Status (1)

Country Link
WO (1) WO2011145108A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9492559B2 (en) * 2014-01-21 2016-11-15 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
JP7111799B2 (en) * 2017-07-05 2022-08-02 インベントプライズ リミテッド ライアビリティ カンパニー Polysaccharide purification for vaccine production using lytic enzymes, tangential flow filtration, and multimode chromatography
US20210070890A1 (en) 2019-09-06 2021-03-11 Serum Institute Of India Private Limited Method for obtaining purified bacterial polysaccharides
CN114853917A (en) * 2022-04-22 2022-08-05 兰州生物制品研究所有限责任公司 Methods for preparing pneumococcal capsular polysaccharide and pneumococcal vaccine

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060228381A1 (en) * 2005-04-08 2006-10-12 Wyeth Separation of contaminants from Streptococcus pneumoniae polysaccharide by pH manipulation
WO2007047749A1 (en) * 2005-10-18 2007-04-26 Novartis Vaccines And Diagnostics Inc. Mucosal and systemic immunizations with alphavirus replicon particles
US20080286838A1 (en) * 2007-03-23 2008-11-20 Wyeth Shortened purification process for the production of capsular streptococcus pneumoniae polysaccharides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060228381A1 (en) * 2005-04-08 2006-10-12 Wyeth Separation of contaminants from Streptococcus pneumoniae polysaccharide by pH manipulation
WO2007047749A1 (en) * 2005-10-18 2007-04-26 Novartis Vaccines And Diagnostics Inc. Mucosal and systemic immunizations with alphavirus replicon particles
US20080286838A1 (en) * 2007-03-23 2008-11-20 Wyeth Shortened purification process for the production of capsular streptococcus pneumoniae polysaccharides

Also Published As

Publication number Publication date
WO2011145108A2 (en) 2011-11-24

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