WO2011135581A8 - Pharmaceutical compositions of dronedarone - Google Patents

Pharmaceutical compositions of dronedarone Download PDF

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Publication number
WO2011135581A8
WO2011135581A8 PCT/IN2011/000270 IN2011000270W WO2011135581A8 WO 2011135581 A8 WO2011135581 A8 WO 2011135581A8 IN 2011000270 W IN2011000270 W IN 2011000270W WO 2011135581 A8 WO2011135581 A8 WO 2011135581A8
Authority
WO
WIPO (PCT)
Prior art keywords
dronedarone
pharmaceutical compositions
composition
devoid
surfactant
Prior art date
Application number
PCT/IN2011/000270
Other languages
French (fr)
Other versions
WO2011135581A3 (en
WO2011135581A2 (en
Inventor
Sunilendu Bhushan Roy
Sushrut Krishnaji Kulkarni
Ajay Kumar Handa
Pranav Dhirajbhai Jogani
Original Assignee
Cadila Healthcare Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cadila Healthcare Limited filed Critical Cadila Healthcare Limited
Publication of WO2011135581A2 publication Critical patent/WO2011135581A2/en
Publication of WO2011135581A8 publication Critical patent/WO2011135581A8/en
Publication of WO2011135581A3 publication Critical patent/WO2011135581A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

A pharmaceutical composition is disclosed, said composition comprising dronedarone or pharmaceutically acceptable salts thereof, wherein said composition is devoid of surfactant.
PCT/IN2011/000270 2010-04-28 2011-04-26 Pharmaceutical compositions of dronedarone WO2011135581A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1354MU2010 2010-04-28
IN1354/MUM/2010 2010-04-28

Publications (3)

Publication Number Publication Date
WO2011135581A2 WO2011135581A2 (en) 2011-11-03
WO2011135581A8 true WO2011135581A8 (en) 2011-12-29
WO2011135581A3 WO2011135581A3 (en) 2012-04-12

Family

ID=44629169

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2011/000270 WO2011135581A2 (en) 2010-04-28 2011-04-26 Pharmaceutical compositions of dronedarone

Country Status (1)

Country Link
WO (1) WO2011135581A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012085284A2 (en) * 2010-12-24 2012-06-28 Krka, D.D., Novo Mesto High drug load pharmaceutical formulations comprising dronedarone and its pharmaceutically acceptable salts
FR2977495B1 (en) * 2011-07-07 2014-03-07 Sanofi Sa PHARMACEUTICAL COMPOSITION AND SOLID GALENIC FORM WITH HIGH DRONEDARONE CONTENT AND PROCESS FOR PREPARING THE SAME
WO2013024411A1 (en) 2011-08-12 2013-02-21 Lupin Limited Co-milled formulation of dronedarone
JP2015507003A (en) * 2012-02-20 2015-03-05 ルピン・リミテッドＬｕｐｉｎ Ｌｉｍｉｔｅｄ Dronedaron double-layer tablets
CN103565763B (en) * 2012-07-26 2016-09-07 山东新时代药业有限公司 A kind of Dronedarone hydrochloride tablet and preparation method thereof
WO2016120299A1 (en) * 2015-01-28 2016-08-04 Sanovel Ilac Sanayi Ve Ticaret A.S. Orally disintegrating formulations of dronedarone

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2665444B1 (en) 1990-08-06 1992-11-27 Sanofi Sa AMINO-BENZOFURAN, BENZOTHIOPHENE OR INDOLE DERIVATIVES, THEIR PREPARATION PROCESS AND THE COMPOSITIONS CONTAINING THEM.
FR2746013B1 (en) * 1996-03-18 1998-05-29 Sanofi Sa USE OF ANTIARRHYTHMIC COMPOUNDS IN THE PREVENTION OF POST INFARCT MORTALITY
FR2764800B1 (en) 1997-06-23 1999-09-10 Sanofi Sa SOLID PHARMACEUTICAL COMPOSITION CONTAINING BENZOFURAN DERIVATIVES
FR2875409B1 (en) 2004-09-17 2010-05-07 Sanofi Aventis PHARMACEUTICAL COMPOSITION COMPRISING A SOLID POLYMERIC MATRIX DISPERSION COMPRISING A CONTINUOUS PHASE OF POLYDEXTROSE AND A CONTINUOUS PHASE OF A POLYMER OTHER THAN POLYDEXTROSE
CN100560067C (en) * 2006-09-29 2009-11-18 北京德众万全药物技术开发有限公司 Hydrochloric acid dronedarone medicinal compositions for oral use and preparation method thereof
MX2010011414A (en) 2008-04-17 2011-03-15 Sanofi Aventis Use of dronedarone for the preparation of a medicament for use in the prevention of cardiovascular hospitalization or of mortality.

Also Published As

Publication number Publication date
WO2011135581A3 (en) 2012-04-12
WO2011135581A2 (en) 2011-11-03

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