WO2011120203A1 - Système sans fil pour une surveillance en temps réel locale/à distance à paramètres multiples - Google Patents

Système sans fil pour une surveillance en temps réel locale/à distance à paramètres multiples Download PDF

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Publication number
WO2011120203A1
WO2011120203A1 PCT/CN2010/000427 CN2010000427W WO2011120203A1 WO 2011120203 A1 WO2011120203 A1 WO 2011120203A1 CN 2010000427 W CN2010000427 W CN 2010000427W WO 2011120203 A1 WO2011120203 A1 WO 2011120203A1
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WIPO (PCT)
Prior art keywords
node
monitoring
communication
gateway node
ecg
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PCT/CN2010/000427
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English (en)
Chinese (zh)
Inventor
陈浩然
Original Assignee
Chen Haoran
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Priority to PCT/CN2010/000427 priority Critical patent/WO2011120203A1/fr
Publication of WO2011120203A1 publication Critical patent/WO2011120203A1/fr

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Classifications

    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04B—TRANSMISSION
    • H04B13/00—Transmission systems characterised by the medium used for transmission, not provided for in groups H04B3/00 - H04B11/00
    • H04B13/005—Transmission systems in which the medium consists of the human body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • A61B5/0006—ECG or EEG signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A61B5/0024—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system for multiple sensor units attached to the patient, e.g. using a body or personal area network
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04W—WIRELESS COMMUNICATION NETWORKS
    • H04W84/00—Network topologies
    • H04W84/18—Self-organising networks, e.g. ad-hoc networks or sensor networks

Definitions

  • the utility model relates to a wireless multi-parameter near-distance real-time monitoring system based on wireless ECG or other parameter collecting nodes and a body area network, belonging to a wireless sensor, a wireless sensor network, a body area network, an electrocardiogram and other parameters. Remote real-time monitoring area. .
  • the collection of human physiological and pathological information is an important part of the doctor's diagnosis and treatment work in hospitals.
  • the parameters related to vital signs such as ECG, blood pressure, respiration, pulse, body temperature and oxygen saturation, are important monitoring for patients in ICU CCU and other wards. Indicators are also the main monitoring indicators for high-risk groups outside the hospital.
  • the cause of sudden death is the first place in cardiovascular disease, accounting for more than half. At present, due to the lack of effective monitoring, most of the cardiac arrests have died outside the hospital, accounting for 60%-70%, of which 1/2-3/4 died at home, and 8-12% died at work. % died in public places.
  • the occurrence of other non-fatal cardiovascular events is also highly random, ranging from several times a day to several times a year.
  • the frequency, occasion, and time of occurrence cannot be predetermined.
  • the duration of the event is several seconds to several hours.
  • the reason for the occurrence is also unclear because there is no ECG information at the time of the attack. After the event, the hospital will obtain the information, which may not help determine the cause.
  • Cardiovascular patients in the hospital are mostly acute, critical, and critically ill patients, including those in the Department of Cardiology and other departments that need to monitor vital signs. They need real-time monitoring of physiological parameters such as ECG, respiration, pulse, Body temperature, blood oxygen saturation.
  • Special custodial objects special people such as the word Navigator, pilots, athletes, soldiers, etc. or animals that need to be protected or studied.
  • the device with many ECG lead wires such as the remote ECG monitoring system disclosed by the patent CN200977158Y, is used for in-hospital and external communication, and realizes the remote communication between the ECG acquisition module (ECG monitor) and other components of the system, with 12 leads. ECG collection capability, but the ECG acquisition module and the electrode are still wired, resulting in:
  • Patients in the hospital are connected to many pipelines, and more than 70% are connected to the electrode wires or pipelines of the multi-parameter monitor, which affects the basic life activities and comfort of the monitoring object, such as the condition Indoor and outdoor activities in the situation: turning over, sitting up, urinating, bedside activities, affecting the psychological state of the patient, combating the confidence of their recovery, from psychological to physiological affect the recovery of the patient, it is also difficult for patients to receive long-term monitoring The important reason.
  • Portable devices with less ECG lead wires such as CN201005693Y, CN101474068A, “Study on wireless sensor-specific wearing monitoring system” and “Research on remote monitoring system based on wireless sensor network”, the disadvantages are as follows:
  • the integration degree is not high.
  • the ECG acquisition and analysis module is made of integrated circuit board (PCB), which is about 20-40 times larger than the mobile phone T-F card. The device is still large and has room for reduction.
  • PCB integrated circuit board
  • the wearable ECG electrode vest with data recording device disclosed in the patent CN200920089699 miniaturizes the ordinary Holter, has no monitoring function, the data recording device is placed in the pocket, and the 6 electrodes are on the vest by the electrode line and the data.
  • the collection device is connected, the model of the vest and the user
  • the vest is tight, so that the electrode is in close contact with the body; because the electrode and electrode wire are sewn together with the vest, the vest can not be washed and washed normally, only lightly washed, up to 30 times, can not be given For personal use; because it is impossible to predict how many times a patient will use it, there may be a possibility that it will be discarded when it is used less than 30 times; there are 3-6 leads on the chest, and there are no critical 6 limb leads, ECG display It's not a standard ECG, the diagnostic value is greatly reduced; the tight vest is also difficult to comfort because of tightness.
  • Patent CN201005693Y discloses a wireless ECG acquisition and GPS positioning device for use outside the hospital and outdoors. ECG acquisition and patient positioning communication are realized, and remote monitoring can be performed. However, there is still a line between the ECG acquisition module and the electrode. The monitoring is limited to the chest, and there are no critical 6 limb leads.
  • the portable wireless ECG monitoring device disclosed in the patent CN101474068A is used in and out of the hospital to realize portable monitoring.
  • the transmission distance is limited (about 100 m), and is connected to the hospital peripheral monitoring device through the USB module.
  • access the Internet for remote monitoring; but because there is no remote communication module (such as GPRS), it can not be used outside the hospital, ward or home, beyond Zigbee wireless transmission range; its electrodes are wired, Only 3 leads on the chest.
  • the present invention provides a wireless multi-parameter near-distance real-time monitoring system based on wireless ECG or other physiological parameter acquisition nodes and body area networks, so that the monitoring object can obtain more activity space when the condition allows. And comfort, while obtaining more accurate and comprehensive pathophysiological parameters.
  • the core components of the system include: acquisition node, wireless body area network, gateway node, wireless ⁇ or wired LAN ⁇ mobile network, RF communication module, human interface module, USB module, main server, monitoring terminal and Internet. among them:
  • the monitoring system includes a short-range real-time monitoring system and a remote real-time monitoring system; the communication includes: the monitoring object wears the same group of collecting nodes and the gateway node wirelessly communicates via the wireless body area network, and the interactive communication of other parts of the system includes:
  • the communication of the gateway node includes:
  • Short-range monitoring The monitoring object is in the same hospital as the monitoring terminal ⁇ main server, a. Short-distance gateway node ⁇ portable short-distance multi-parameter monitor and monitoring terminal ⁇ main server are connected through the same wireless LAN to realize short-range monitoring The node is worn on the monitoring object. b. The short-distance gateway node is inserted into the non-portable computer to form a non-portable multi-parameter monitor, and the latter is connected to the monitoring terminal ⁇ main server through the same cable. The local area network is connected to realize short-range monitoring, and the node is not worn on the monitoring object;
  • Short-distance gateway node ⁇ portable short-distance multi-parameter monitor and monitoring terminal ⁇ main server are not in the same LAN, short-distance gateway node and portable short
  • the multi-parameter monitor is wirelessly connected to the non-portable human-machine interface module with the radio frequency communication module through the local wireless local area network, and the latter is connected to the Internet through the wired local area network, and accesses the remote monitoring terminal ⁇ the local area network where the main server is located, and completes the remote operation.
  • Monitoring b.
  • the short-distance gateway node is inserted into the non-portable human-machine interface module to form a non-portable multi-parameter monitor. The latter is connected to the local wired LAN, connected to the Internet, and then connected to the remote monitoring terminal ⁇ the main server. Or wireless LAN, complete remote monitoring ⁇ ;
  • Long-distance dual-purpose gateway node Long-distance dual-purpose monitor and monitoring terminal ⁇
  • the main remote server communicates with the short-distance gateway node ⁇ portable short-distance multi-parameter monitor when it is in the local wireless LAN communication range;
  • the communication of the monitoring terminal includes:
  • Portable short-distance monitoring terminal short-range: communicates with the gateway node and its own collection node or main server through the wireless LAN in the hospital;
  • Remote accesses the main server via the remote wireless LAN, the main server is connected to the Internet ⁇ wirelessly connected via the remote local area network The Internet, which then enters the local area network where the monitoring object is located, and communicates remotely with the gateway node and the associated collection node;
  • Non-portable short-distance monitoring terminal short-range: Through the hospital's wireless LAN ⁇ wired LAN, communicate with the gateway node and its own collection node ⁇ main server; Remote: Connect to the main server via the remote LAN, the main server is connected to the Internet ⁇ The local area network is connected to the Internet, and then enters the local area network where the monitoring object is located, and communicates with the gateway node and the associated collection node;
  • the long-distance dual-purpose monitoring terminal includes accessing the Internet through the mobile network to communicate with the main server ⁇ gateway node and the associated collection node, and is mainly used for experts located outside the communication range of the wireless local area network; also includes the wireless local area network and the main server ⁇ monitoring terminal ⁇ gateway The node and the associated collection node communicate; when the monitoring object is in the hospital, the proximity monitoring is completed, and when not in the same hospital, the remote monitoring is completed; the wireless body area network includes:
  • the collection node and the gateway node of the same group are configured to communicate within the radio communication distance of the collection node and the gateway node, and comply with the radio frequency communication protocol, including: Zigbee ⁇ Simplici, which can program the communication distance of the node.
  • the LAN includes:
  • Short-range monitoring It consists of a gateway node, a monitoring terminal, and a main server in the same hospital, and complies with the radio frequency communication protocol, including Zigbee, Simplici;
  • the remote end is composed of a gateway node in the same residential area and a non-portable human-machine interface module with a radio frequency communication module inserted therein.
  • the near-end is a remote monitoring terminal ⁇ main server and a non-portable HMI with a radio frequency communication module inserted therein.
  • Interface module composition comply with RF communication protocols, including Zigbee, Simplici;
  • Short-range monitoring consists of non-portable monitors, non-portable monitoring terminals, main servers and local area networks in the same hospital, complying with the aforementioned wired communication protocols;
  • the remote end consists of a non-portable HMI module in the same residential area and a local area network; the near end consists of a non-portable monitoring terminal ⁇ main server in the same hospital and a local area network, obeying the aforementioned wired communication protocol.
  • the communication of the main server includes: The main server is connected to the monitoring terminal and the gateway node and the collecting node via the local area network or the Internet.
  • the collection nodes include:
  • ECG acquisition node wireless blood pressure collection node, wireless respiratory collection node, wireless pulse acquisition node, wireless body temperature acquisition node, Wireless oxygen saturation acquisition node and combination of these collection nodes;
  • ECG acquisition node is a 3-18 lead wireless ECG acquisition node, which can perform 3 to 18 lead ECG monitoring;
  • the ECG acquisition node or other micro-wireless physiological parameter sensor can be fixed in a conventional manner or fixed in any other way.
  • the wireless ECG sensor or other wireless physiological parameter sensor collects electrical or other physiological parameters, and is input into the acquisition node for processing, including: , filtering, analog-to-digital conversion, compression, encryption, tag address and time, and wireless communication with the gateway node to form a wireless body area network, the communication distance can be programmed within a certain range; providing a gateway node to generate a 3-18 lead electrocardiogram Data on ECG data or other parameters; '
  • the structure comprises: a wireless electrocardiographic sensor or other physiological parameter microsensor; an amplifying circuit and a filtering circuit for weak parameters; an analog to digital conversion circuit; a memory for storing electrocardiographic data and other physiological parameters; and a central processing unit for transmitting and receiving signals Processing, managing each part of the entire node; a circuit for time synchronization circuit and address allocation with the system; an identification circuit for marking the time and address of collecting ECG data and other physiological parameters; the address of the collection node is included The name of the marker of the same group gateway node, the name of the ECG electrode and other physiological parameter collection nodes; the software for compressing the ECG data and other physiological parameters; the clock circuit for providing the normal operation of the central processor unit;
  • the communication RF communication module includes a control circuit for controlling the interface of the RF communication module; a circuit for controlling the three working modes of the collection node to be turned off, sleeping, and activating; a circuit for controlling the communication distance; and a power supply unit: for providing the node Normal working power supply; the
  • Gateway nodes include:
  • the collection node of the group constitutes a wireless body area network, can be connected to the local area network ⁇ mobile network, identify the address of the ECG data from the collection node, decompress and decrypt the ECG data with the group mark, and extract the same time ECG data, analysis and processing of each collection node, and integration of ECG, forming ECG data of each lead, storing ECG data in the node itself or externally expanding Flash; or forming a monitor with a human-machine interface module, Displaying an electrocardiogram on the human-machine interface module, and printing the electrocardiogram through the human-machine interface module; transmitting real-time or historical electrocardiogram data to the monitoring terminal or the main server, receiving the instruction of the monitoring terminal or the main server, and transmitting the instruction to the relevant collection node; Mode and communication distance can be programmed; time synchronization circuit for timing with system and circuit for accepting assigned address; identification, decompression, decryption of other physiological parameter data from acquisition node, storage in node itself or expansion Flash ⁇ is displayed on the
  • Gateway node types include:
  • 'Structure includes: RF communication module: used to access wireless body area network ⁇ wireless LAN; microprocessor (MCU): used for time synchronization circuit and acceptance assigned to the system Circuit of address; circuit for decompression and decryption; identification circuit for identifying mark collection time and address ECG data; for 3-18 lead ECG signal extraction, amplification, analysis, calculation, completion of each guide Generation of electrocardiogram, microprocessor showing electrocardiographic parameters and other physiological parameters; software for compressing synthesized electrocardiogram data and other physiological parameters; memory for storing synthesized electrocardiogram data and other physiological parameters; electrocardiogram and other physiological parameters Management software; the time used to mark the occurrence of ECG and other physiological parameters and the address of
  • the structure includes: RF communication module: RF communication module for communication with the acquisition node ⁇ and the monitoring terminal ⁇ main server; Remote communication and positioning module: including: GSM ⁇ GPRS ⁇ CDMA ⁇ W-CDMA ⁇ CDMA2000 ⁇ TD-SCDMA and GPS Module; structure other than the short-distance gateway node RF communication module;
  • Multi-parameter monitor It is a human-machine interface module with a short-distance gateway node and a long-distance dual-purpose gateway node. It is also a gateway node: In addition to the function of the corresponding gateway node, it can passively or actively read the monitored object in real time or historically. Electric or other physiological parameters, realize the interaction between the machine and the monitoring terminal ⁇ main server; - Multi-parameter monitor types include:
  • Portable multi-parameter short-range monitor plug-in ⁇ human-machine interface module embedded in short-distance gateway node, including portable dedicated embedded terminal, high-end mobile phone or PDA, can access wireless body area network and wireless local area network;
  • Non-portable multi-parameter short-range monitor The human-machine interface module inserted into the embedded short-distance gateway node, including any form of non-portable computer connected to the Internet, can access the wireless body area network and the wireless local area network ⁇ wired LAN;
  • Long-distance dual-purpose multi-parameter monitor Human-machine interface module plugged into the long-distance distance monitoring dual-use gateway node, including portable dedicated embedded terminal, high-end mobile phone or PDA, can access wireless body area network and mobile network ⁇ wireless local area network ;
  • the monitoring terminal includes - managing the data and communication of the system's ECG and other parameters, and can be used inside and outside the hospital.
  • Monitoring terminal software includes:
  • ECG and other physiological parameter management software actively or passively read real-time or historical data of ECG and other physiological parameters of the monitored object from the ECG and other physiological parameter databases, display and analyze the data;
  • ECG and other physiological parameters The monitoring terminal can simultaneously display data of multiple patients or data of a single patient according to the size of the LCD, and can freely select data to be monitored according to the needs of monitoring; when the abnormality of the electrocardiogram and other physiological parameters of the monitoring object occurs, the Internet actively Initiating a connection to the monitoring terminal, and transmitting the patient's real-time ECG data; the ECG and other physiological parameter monitoring terminals send alarm information and medical treatment opinions to the monitoring personnel through SMS, voice, and video;
  • the communication management software includes: communication control software manages the collection node, the gateway node, the access control of the monitoring terminal and the main server, the authority control, the communication, etc., maintains the database data of the electrocardiogram and other physiological parameters; and controls the collection node and the gateway node to be closed Circuit for sleeping and activating three working modes; circuit for controlling the communication distance of the acquisition and gateway nodes; assigning, grouping, naming, and timing the collection node and the gateway node; and reading the monitoring object through the main server Real-time or historical electrocardiogram and other physiological parameter data, display and perform data analysis and processing; manage the power of the collection node and the gateway node and the circuit for collecting the paste state of the node;
  • the monitoring terminal structure includes:
  • Man-machine interface module liquid crystal display, keyboard, sound, video multimedia component for displaying ECG characteristic parameters and other parameters; sounding alarm circuit for controlling alarm device;
  • Communication module RF communication module ⁇ remote communication module ⁇ wired communication module, including: Ethernet, RJ-485 and ADSL, or remote communication module: including: GSM ⁇ GPRS ⁇ CDMA ⁇ W-CDMA ⁇ CDMA2000 ⁇ TD-SCDMA module;
  • Power supply unit Power circuit plus battery or other power supply, used to provide power for the entire human-machine interface module; monitoring terminal can be used for indoor/outdoor portable dedicated embedded terminal, high-end mobile phone or PDA and more for indoor use.
  • Monitoring terminal types include:
  • Portable multi-parameter short-distance monitoring terminal plug-in/embedded RF communication module human-machine port module, including portable dedicated embedded Terminal, high-end mobile phone or PDA, can access wireless LAN;
  • Non-portable multi-parameter short-distance monitoring terminal Insert ⁇ Embedded RF communication module ⁇ Human-machine interface module of wired communication module, including any form of non-portable computer connected to the Internet, can access wireless LAN ⁇ wired LAN;
  • the main server is used in medical institutions, including:
  • the ECG and other physiological parameter servers include: ECG and other physiological parameter databases, communication control software and communication modules.
  • the database of ECG and other physiological parameters includes: stored patient ECG and other physiological information, as well as personal data of patients, nurses and doctors;
  • Communication control software includes: ⁇ Management of acquisition nodes, gateway nodes, monitoring terminals and access to the main server Control, authority control, communication, etc., maintain database data of ECG and other physiological parameters; address allocation, grouping, naming, and timing of collection nodes and gateway nodes; used to control collection node and gateway node shutdown, sleep, activation Circuit of working mode; circuit for controlling the communication distance of the collecting node and the gateway node.
  • Communication module RF communication module
  • ⁇ Wired communication module includes: Ethernet, RJ-485 and ADSL, can be connected with wired ⁇ wireless LAN, and then connected to the Internet and mobile network.
  • the human interface module includes:
  • the RF communication module includes:
  • Used for wireless body area network ⁇ wireless LAN communication integrated in the collection node, gateway node; or embedded or inserted into the human interface module, such as: computer, monitor, monitoring terminal, main server; embed it in the hospital
  • the human interface module can be inserted into the human interface module through the USB module outside the hospital.
  • the USB module includes:
  • the network communication protocols use standard open protocols, including:
  • the communication between the node and the gateway node adopts the Zigbee or simplici protocol;
  • the wireless communication between the gateway node and the monitoring terminal ⁇ main server ⁇ human interface module with the RF communication module adopts the Zigbee or simplici protocol;
  • the gateway node and the monitoring terminal ⁇ Wired communication between the main servers using wired communication modules, including Ethernet, RJ-485 and ADSL, and complying with relevant protocols;
  • Adopt relevant protocols such as: GPRS controlled by MCU adopts IP over PPP and TCP/IP protocol;
  • the monitoring object can carry out near-distance monitoring only with the acquisition node or the portable gateway node, and the node data transmission is wireless, and the constraint of the pipeline to the monitoring object is removed;
  • the hospital monitoring object such as ICUXCCU: can at least reduce the ICU ⁇ CCU patient body. % of the pipeline; reduce the psychological pressure of the patient, can also enable the patient to complete various rehabilitation training if the condition allows, which is conducive to the recovery of the disease;
  • the external monitoring object of the hospital can also be conveniently fixed in the need to collect ECG information and Other physiological parameters of the object - an ordinary patient and other special monitoring objects.
  • the chips used in the acquisition node and gateway node are synthesized based on CMOS technology, which is very small, ranging from 3mm to 7mm. Then the chip chip is packaged in micro-package technology (without PCB, such as the patent CN101474068A portable module has an overall size of 3cm).
  • the interface module is miniaturized and portable, easy to use indoors and outdoors, and is easy to accept for objects that require long-term monitoring. It is also a prerequisite for long-term monitoring. With the miniaturization of CMOS chips and the maturity of MEMS chips, it is expected that the acquisition nodes will be made lxlxlmm in the future. For example, Smart dust used by the US military can be as small as a TF card.
  • the collection node and the portable gateway node are wireless, highly integrated, miniaturized, and portable, the number of leads to be monitored by the monitoring object is easily increased, especially the limb lead, which can be like a conventional electrocardiogram in 3-18.
  • the selection of the collection nodes between the leads makes the collected ECG data more comprehensive and more diagnostic.
  • the chips of the collection node and the gateway node all use ultra-low power consumption, high integration, and programmable chips. These chips have multiple working modes, and the sleep state consumes only a few microamps, and a button battery is
  • the collection node and the indoor gateway node can supply power for one day to several tens of days. The power consumption of a single node is very low.
  • a large capacity battery of a mobile phone can supply the outdoor indoor dual-purpose gateway node for several days, which is one of the keys to long-term monitoring. ;
  • the transmission distance of the programmable acquisition node can be 5m, so that the power consumption of the collection node is the lowest, and the data of the collection node is received by the short-distance gateway node within 5m.
  • the B collection node is on the monitoring object.
  • the gateway node can obtain the power supply of the human-machine interface module through the USB interface, especially when inserting or embedding on the non-portable computer, the power supply can be infinitely long.
  • Time such as: When the monitoring object is in ICU ⁇ CCU ⁇ or at home, wear the collection node with a distance of only 5m, and transmit the data to the indoor multi-parameter monitor (home PC+ indoor gateway node can be composed), which is the lowest power consumption.
  • home PC+ indoor gateway node home PC+ indoor gateway node can be composed
  • Smart dust a MEMS chip with solar self-charging, will be market-oriented and civilized, and will greatly extend its vitality.
  • the acquisition node and the gateway node composed of the CMOS-based chip module are low in cost;
  • the human-machine interface module of this system is widely used at present; the short-distance and long-distance distance gateway nodes are easy to access the USB module, and the human-machine interface module for household or unit can increase its utilization rate;
  • the near and long-distance transmission of the system uses open protocols and networks, such as: Remote: IP over PPP and TCP IP; Proximity: Zigbee ⁇ Simplici; Remote transmission does not need to be re-routed, and wired transmission costs are increasingly low.
  • Free coverage of mobile network free wireless Internet access in Beijing North Fourth Ring Road and South Second Ring Road, wireless coverage in other parts of the country, 3G and 4G communication also laid the foundation for improving communication efficiency, Zigbe e ⁇ for short-range transmission
  • the Simplici RF communication module which forms a wireless body area network and a wireless LAN, saves the cost of transmission.
  • the chips of the collection node and the gateway node are small, low-power, durable, and can be replaced at any time.
  • the collection node and the gateway node are wireless, the system components and the communication are low-cost, the monitoring object is easy to receive long-time monitoring, and the data can be stored in the portable Dedicated embedded terminal ⁇ Mobile ⁇ PDA expansion card ⁇ or send it to the main server at any time, because the expansion card (expanding card storage capacity is increasingly powerful, some have reached 36G) and the computer's hard disk can be exchanged without limit, in theory
  • the collection of ECG information can be infinitely long, which means that the monitoring time is almost unlimited.
  • the analog-to-digital converter has high sampling accuracy (1000Hz-10000Hz controllable), the signal is digital technology, the microprocessor has high performance (processing speed up to 125ns) and the software has high data processing capability, which can have stable baseline and high Signal noise ratio, EKG quality is more stable and reliable;
  • Both professional and non-professionals are easy to master: Acquisition and display can be done very simply. Users only need to paste the collection nodes according to the instructions. Short-distance gateway nodes ⁇ long-distance dual-purpose gateway nodes can be flexibly embedded or inserted. Human interface module, especially Inserting the USB interface is easy for non-professionals; the human-machine interface modules of the monitor and monitoring terminal are various, portable or non-portable for use in hospitals or outside hospitals, and the monitoring object only wears the collection node or carries the portable gateway node.
  • the one-button OK mode of the mobile phone can be used for ECG collection analysis display transmission; it can be used in a popular manner, and is more useful and convenient than the current similar products.
  • Multi-function, multi-purpose machine 8.
  • the gateway node can store the ECG and other physiological parameter data in the node itself or in the externally-expanded Flash, and print the electrocardiogram through the human-machine interface module, so in addition to the above "cardiac monitoring" function, there is also an electrocardiograph.
  • electrocardiograph 24-hour dynamic electrocardiograph function; professional or non-professionals can collect ECG immediately or later at a certain time for analysis, especially non-professionals can collect ECG data at the time of medical incident, real-time transmission or after-the-fact The analysis of professionals provides a basis for diagnosis and treatment.
  • the chips used are made of mature CMOS production technology. The performance and durability of these products are very good.
  • the human interface module is also commonly used, so no special maintenance experience and technology are required, and it is easy for users. accept.
  • the system can be connected to the Internet to achieve global data sharing
  • Short-range monitoring acquisition node + wireless body network + gateway node (with ⁇ UAD interface module) + LAN (wired ⁇ wireless) ⁇ mobile network + ECG monitoring terminal and main server + Internet; and:
  • Remote monitoring acquisition node + wireless domain network + gateway node (with ⁇ UAD interface module) + LAN (wireless ⁇ wired) ⁇ mobile network + Internet + LAN + ECG monitoring terminal and main server
  • this data transmission method is the most economical, timely, convenient, and globally accessible, and it is suitable for remote and remote data sharing. It is conducive to the consultation of medical experts without time and space obstacles, and provides medical advice to users.
  • the user can make a request by SMS and call.
  • the patient simply presses the button, and the ECG and other physiological parameters are transmitted to the monitoring center or the doctor's computer.
  • the doctor can use the ECG and other physiological parameters. , to provide medical advice for the monitoring object.
  • the collection node worn by the monitoring object or the portable gateway node is wirelessly transmitted, combined with the functions of miniaturization, low power consumption, and real-time long-term monitoring, which maximizes the activity and comfort of the monitoring object, and can satisfy indoor and outdoor.
  • Near-distance monitoring seamlessly connected, all-weather, all-lead ECG and its: & physiological parameters collection, analysis, launch, display, storage system.
  • V 1 is a system frame diagram of the present invention, wherein I, II, III, a V R, avL, AVF, Vl, V2, V3, V4, V5, V6 are the name of the lead formed by the ECG collecting node.
  • the location is the glued node of the collection node, the connection line is the wired or wireless communication line, the arrowless connection is the connection of the short-range communication, and the double arrow is the connection of the remote communication.
  • FIG. 2 is a block diagram of the system remote monitoring
  • FIG. 3 is a block diagram of the system short-range monitoring
  • Figure 4 is a block diagram of the acquisition node.
  • Figure 5 is a block diagram of a short-range gateway node.
  • Figure 6 is a block diagram of a long-and short-distance dual-purpose gateway node.
  • FIG. 7 is a block diagram of the amplifier circuit I NA333
  • FIG. 8 is a block diagram of the analog-to-digital converter ADS 1251
  • Figure 9 is a block diagram of the Zigbee RF communication module CC2531.
  • FIG. 10 is a block diagram of the microprocessor MSP430FG461 X.
  • Figure 1 1 is the block diagram of GPS HX821 1
  • Figure 12 is a block diagram of the GSM/GPRS module.
  • FIG. 13 is a block diagram of the power supply circuit TPS61029DRC.
  • FIG. 1 12-lead ECG monitoring is taken as an example.
  • the embodiment includes: a wireless ECG collection node, a wireless body area network, a gateway node, a wireless/wired LAN, a mobile network, a radio frequency communication module, and a human-machine interface module. , USB module, main server, monitoring terminal, internet.
  • the communication of the monitoring system is shown in Figure 1, Figure 2 and Figure 3:
  • the collecting node collects the signal through the wireless sensor (electrocardiographic patch electrode), after the initial processing by the collecting node, it is transmitted to one of the gateway nodes in the figure through the body area network, and the gateway node only identifies the signal that receives the same group of collecting nodes (ie, The collection node of a monitoring object is integrated to form a standard lead electrocardiogram, which is displayed in real time on the human-machine interface module of the short-distance gateway node/short-range multi-parameter monitor, and simultaneously through the network 1 in FIG. 1 and FIG.
  • Long-distance dual-purpose gateway node and long-distance dual-purpose monitor and monitoring terminal ⁇ main server exceed the short-range RF wireless communication range, need to connect to the Internet via mobile network, complete short-range monitoring in the same hospital; not in the same hospital Internal monitoring, complete remote monitoring;
  • the wireless body area network includes:
  • the communication distance of the body area network in this case can be adjusted within 5-100m.
  • the LAN includes:
  • Short-range monitoring It consists of a gateway node, a monitoring terminal, and a main server in the same hospital, and complies with the radio frequency communication protocol, including Zigbee, Simplici;
  • the remote end consists of a gateway node in the same residential area and a non-portable human-machine interface module with a radio frequency communication module.
  • the near-end is a remote monitoring terminal ⁇ main server and a non-portable HMI with a radio communication module.
  • Interface module composition comply with RF communication protocols, including Zigbee, Simplici;
  • Wired LAN as shown in Figure 1, Figure 2, Figure 3
  • Short-range monitoring consists of non-portable monitors, non-portable monitoring terminals, main servers and local area networks in the same hospital, complying with the aforementioned wired communication protocols;
  • the remote end consists of a non-portable computer in the same residential area and a local area network; the near-end is composed of a non-portable monitoring terminal ⁇ main server and a local area network, and complies with the aforementioned wired communication protocol.
  • the wireless ECG node is attached to the limb and chest as shown in Figure 1, Figure 2, Figure 3. It is located in I, II, III, avR, avL, avF, VI, V2, V3, V4, V5, V6.
  • I and avR, II and avL, III and avF each share an ECG acquisition node, VI, V2 V3, V4, V5, V6 each have an acquisition node, 9 acquisition nodes complete 12 leads Collection of ECG signals;
  • connection between the collection node and the body area network is the wireless communication virtual line; the connection between the other components in Figure 1, Figure 2, and Figure 3 is the communication line between the two,
  • the part connecting the arrow of the arrow is the short-range communication part, and the part connected by the double-arrow line is the remote communication part.
  • the node is electrically connected to the preamplifier circuit module by the wireless chip microelectrode
  • the preamplifier circuit module is electrically connected with the ADC module
  • the ADC module is electrically connected with the Zigbee transceiver module
  • the power supply unit is provided to the acquisition node.
  • Each module is powered. among them:
  • the ECG signal preamplifier module uses a negative feedback differential amplifier circuit to amplify the ECG signal collected by the SMD microelectrode, and then amplifies the signal to the ADC module; the ADC module performs data acquisition, filtering, and analog to digital conversion. , storage and control; data encryption, compression; add the acquisition time and the address identifier of the group and the electrode name; the ADC module also accepts the instructions from the gateway node, including: the system program initialization time, the allocation ID, The ID includes the group and electrode name information of the collection node, such as Vl. l; VI represents the electrode VI, ".1" represents the group, and the other collection nodes of the same group are all ".1", and the gateway node is the same; Instructions for working mode (can be in shutdown, hibernate, active state);
  • Zigbee communication module Receives the data processed by the ADC, transmits/stores the processed data of the ADC, and receives the instructions of the gateway node. Including: Communication distance control command (data emission distance control, such as 5-100m can be adjusted); Work mode instructions (can be in shutdown, sleep, active state); Data real-time transmission ⁇ stored in Zigbee communication module instructions ;
  • the power supply unit supplies power to each module of the collection node.
  • the Panasonic button battery PR675H, 1.4V, 606maH is used, which can supply power to the node for 1 to several days, and the size is small, only the diameter l l.6mmX5.4mm.
  • Short-distance gateway node as shown in Figure 5: The Zigbee communication module is connected to the microprocessor, and the power supply unit supplies power to each module of the gateway node; the long-distance dual-purpose gateway node, as shown in Figure 6: Zigbee communication module and remote communication positioning module and micro The processor is connected, and the power supply unit supplies power to each module of the gateway node;
  • the multi-parameter monitor is composed of a human-machine interface module and a short-distance gateway node and a long-distance distance gateway node, and is also a gateway node, wherein: a human-machine interface module: includes a liquid crystal display for displaying electrocardiographic characteristic parameters (and other parameters), Keyboard, sound, video multimedia components; power supply unit: power circuit plus AC or DC power supply, used to provide power for the entire human interface module; the human interface module can be a portable dedicated embedded terminal with the above components, high-end mobile phone or PDAs and non-portable tablets, desktops or laptops, non-portable line-containing communication modules, including: Ethernet, RJ-485 and ADSL;
  • Multi-parameter monitor types include:
  • Portable multi-parameter short-range monitor Insert the human-machine interface module embedded in the short-distance gateway node, such as: portable dedicated embedded terminal, high-end mobile phone or PDA, can access wireless body area network and wireless local area network;
  • the short-distance gateway node such as: portable dedicated embedded terminal, high-end mobile phone or PDA, can access wireless body area network and wireless local area network;
  • Non-portable multi-parameter short-range monitor A human-machine interface module plugged into the short-distance gateway node.
  • the human-machine interface module is any form of non-portable computer (home PC or other PC) connected to the Internet, and can access the wireless body. Domain network and wireless LAN ⁇ wired LAN;
  • Long-distance dual-purpose multi-parameter monitor Insert/embed the human-machine interface module of the long-distance distance monitoring dual-use gateway node, such as: portable dedicated embedded terminal, high-end mobile phone or PDA, can access wireless body area network and mobile network ⁇ none 'Line LAN;
  • the Zigbee communication module of FIG. 5 receives the ECG data processed by the acquisition node and inputs the microprocessor; and also transmits the lead electrocardiogram generated by the microprocessor and the wireless local area network to the monitoring terminal or the main server to implement monitoring;
  • the commands of the monitoring terminal and the main server include: control of the working mode and the communication distance, and three working modes of closing, sleeping, and activating, and the communication distance can be adjusted within 5-100 m.
  • the Zigbee communication module ⁇ remote communication positioning module of Fig. 6 not only has the function of the communication module of Fig. 5Zigbee, but also transmits the position of the monitoring object to the monitoring terminal or the main server via the wireless local area network ⁇ mobile network, thereby realizing monitoring and positioning;
  • the microprocessor in Figure 5 and Figure 6 includes: a CPU, a peripheral interface, a Flash module, and a USB interface, wherein:
  • the CPU receives the instruction of the monitoring terminal ⁇ server to complete the initialization of the program, including: accepting the system pair, and the address (ID) allocation including the group and the electrode name; accepting the system instruction to make the microprocessor in one of three working modes (off, Sleep, activate); identify the ECG data marked with the address of the collection node, only connect the ECG data of the same group of acquisition nodes, decompress and decrypt the data, and extract 3 of the same group at the same time (accurate to 100 microseconds) 18-lead ECG signal, amplify, analyze, calculate, integrate, and complete the generation of each lead electrocardiogram; mark the ECG generation time and the address of the gateway node according to the ECG acquisition time to mark the occurrence time and object of the ECG; Compressed generated ECG data of each lead, stores ECG data; displays ECG characteristic parameters and other physiological parameters in real time; Flash module is responsible for storage; Peripheral interface is extended to SPI (Serial Peripheral Interface) and Zigbee transcei
  • Power supply unit Power circuit plus button battery ⁇ Mobile phone 3 ⁇ 4 ⁇ USB interface power supply, used to provide power for the node to work normally; For example: Short-distance gateway node + button battery (Panasonic PR675H, 1.4V, 606maH, diameter l l.6mmX5 .4mm); or long-distance dual-purpose gateway node + large-capacity mobile phone battery (greater than 1500maH); or gateway node embedded or inserted into the human interface module USB interface, by human-machine interface module Powered by the USB interface, the power includes: cell phone battery, mains or other.
  • Short-distance gateway node + button battery Pulsonic PR675H, 1.4V, 606maH, diameter l l.6mmX5 .4mm
  • long-distance dual-purpose gateway node + large-capacity mobile phone battery greater than 1500maH
  • gateway node embedded or inserted into the human interface module USB interface by human-machine interface module Powered
  • Monitoring terminal through the Zigbee communication module ⁇ wired communication module ⁇ remote communication module embedded into the human-machine interface module, access wireless/wired LAN ⁇ mobile network (network 1 ⁇ network 2), and communicate with the rest of the system;
  • the communication and ECG management software manages various nodes that enter the jurisdiction, including: assigning an address containing the group and the electrode name to the collection node, and assigning the address of the group of the gateway node; and the acquisition node and the gateway node; Working mode and communication distance of various nodes; active or passive receiving gateway nodes generate real-time or historical electrocardiogram or other physiological numbers, and gateway node nodes connected with man-machines exchange information by means of text, voice, video, etc., such as issuing Consultation opinions and suggestions, accept the request of the node.
  • the main server includes: ECG database, communication control software and communication module.
  • the ECG database includes: stored physiological information such as patient ECG, and personal data of patients, nurses, and doctors, and maintains ECG database data;
  • communication control software includes: management collection node, gateway node, monitoring terminal, and ECG server Access control, authority control, communication, etc., address allocation, grouping, naming, and time-sharing of the collection node and the gateway node; circuit for controlling the three working modes of the collection node and the gateway node to be turned off, dormant, and activated; A circuit for collecting the communication distance between a node and a gateway node.
  • Communication module RF communication module
  • ⁇ Wired communication module includes: Ethernet, RJ-485 and ADSL, which can be connected with wired/wireless LAN, and then connected with the Internet and mobile network to undertake interactive communication with the rest of the system.
  • the human interface module includes:
  • the module can be a portable dedicated terminal, a high-end mobile phone or PDA, and a non-portable tablet, desktop or notebook computer with the above components, including line communication modules, including: Ethernet, RJ-485 and ADSL.
  • the RF communication module includes:
  • the human-machine interface module can be inserted into the human-machine interface module through the USB module outside the hospital.
  • the USB module includes:
  • the ECG signal preamplifier module uses the micro-power meter amplification chip of the company, the model is INA333, the magnification is 1000 times, because the bioelectric signal is very weak, the requirements for the amplifier circuit Very high, INA321A chip is an integrated operation op amp for low power consumption, its characteristics are: small quiescent current; internal gain can be changed by different connections of the pin; high gain precision, and small drift; common mode rejection ratio; The voltage is small; the nonlinear distortion is small; the drift of the offset voltage is small; and the input resistance is high.
  • the ADC mode is selected from the Texas Instruments ADS1251, as shown in Figure 8, for filtering the ECG signal input from the amplifier circuit, analog-to-digital conversion, and sampling time and address of the tag data. With a sampling rate of up to 10,000, the module can not only collect general ECG signals, but also collect pacemaker signals, as well as filtering functions, so there is no need to configure the filter circuit.
  • the RF communication module adopts Chipcon series RF chip of Texas Instruments, model CC2531, as shown in FIG. 9.
  • the RF communication module has a long communication distance, low power consumption, flexible interface of the Zigbee module, and a USB interface. Therefore, the human interface module can be embedded or inserted (included in: acquisition node, gateway node, monitor, monitoring terminal and or main server, computer).
  • the Zigbee protocol has many advantages such as low network usage fee, low equipment investment, reliable communication, good anti-interference, flexible working frequency band, etc., and can achieve good transmission results. It is controlled by software in the power saving mode when it is not working.
  • the microprocessor uses the MSP430FG4619 chip from Texas Instruments, as shown in Figure 10. It integrates CPU, 4KB RAM, 120KBFlash, DAC, LCD driver, peripheral interface and other functional modules. Has a strong data processing capability, execution speed of up to 125ns, wide voltage (1.8 - 3.6V) work. 15.
  • the GSM/GPRS module selects the GSM/GPRS module M22 of BENQ Company as the tri-band module, as shown in FIG.
  • the module integrates a baseband processor, FLASH flash memory, RF interface, normal I/O port, universal asynchronous transceiver, SIM card interface, battery and LED interface.
  • the GPS module uses Xi'an Huaxun Microelectronics Cable Co., Ltd. HX8211, as shown in Figure 11.
  • the power supply circuit uses TPS61029DRC from Texas Instruments RICHTEK, as shown in Figure 13. Used to power other modules in the system.
  • the module has a wide input voltage (0.9-6.5V) and output voltage (1.8-5.5).
  • the power module is required to provide two voltages: 4V, 3V.
  • the GPRS module needs 4V voltage, the current required when transmitting and receiving data is relatively large, and needs about 2A current at the peak time; the front end ECG signal acquisition and processing circuit needs 3V voltage, and the maximum current during operation does not exceed 1A current. . This power supply can be satisfied.
  • the ECG electrode collects the ECG signal through the INA+ VIN+ ⁇ TviN-pin input, the weak ECG signal is amplified in the INA321A, and the amplified ECG signal is passed through INA333.
  • the ECG signal output from the VOUT of the INA333 is filtered, sampled, and analog-digital converted by the ADC module (here ADS1251), compressed, encrypted, plus time and address (group and electrode name), and sent to the acquisition node.
  • the Zigbee RF communication module (CC2531) is transmitted to the gateway node in real time and stored in the acquisition node (communication is shown in Figure 1). '
  • the short-distance gateway node Zigbee radio communication module recognizes the same group of ECG data after receiving the data of the collection node, and sends it to the microprocessor for decompression and decryption, and uses different address sources (different electrodes).
  • the ECG data is extracted; after analysis and synthesis processing, each lead ECG is generated, which can be displayed in real time ⁇ stored in the gateway node Vf exclusively to the monitoring terminal, the main server displays in real time ⁇ storage; the monitoring terminal ⁇ main server also passes The human-machine interface and the monitoring object complete the information interaction (communication as shown in Figure 1, Figure 2, Figure 3).
  • the long-distance dual-purpose gateway node Zigbee RF communication module after receiving the data of the collection node, identifies the same group of ECG data, sends it to the microprocessor for decompression and decryption, and uses different address sources (different electrodes).
  • the ECG data is extracted; after the analysis and synthesis processing, each lead electrocardiogram is generated, which can be displayed in real time ⁇ stored in the gateway node ⁇ The ECG data and location information are transmitted to the Internet via the mobile network through the GPRS ⁇ GPS module.
  • ⁇ «The Zigbee communication module transmits data to the wireless LAN, and finally reaches the monitoring terminal and the main server.
  • the monitoring terminal and the main server display and store the ECG data in real time.
  • the monitoring terminal and the main server also complete the information interaction with the monitoring object through the human machine interface ( The communication is shown in Figure 1, Figure 2 and Figure 3. .
  • the ADS, Zigbee communication chip, MCU, remote communication positioning module, and microprocessor are controlled by the monitoring software of the monitoring terminal ⁇ main server in a power saving mode when not working.
  • the gateway node can be supplied by the mains interface module.
  • Control ADC Zigbee RF communication module
  • MCU working mode off, hibernate, active
  • power consumption is only a few microamps during sleep. Node power consumption can be minimized, which is beneficial for long-term monitoring.
  • the device of this embodiment can be selected in various combinations, especially gateway nodes, wherein: 1. acquisition node + non-portable monitor (non-portable human interface module + indoor gateway node) mode is the most convenient and practical, the lowest power consumption One type, that is, "acquisition node + body area network + non-portable monitor + wired LAN + Internet", in this mode, the power supply duration of the gateway node is unlimited, the collection node can be conveniently attached to the body, and the communication distance is controlled at 5m. The wireless signal (without lead wire) is sent to the non-portable monitor, which is very suitable for indoor monitoring; or 2.
  • “Acquisition node + portable short-distance gateway node + wireless LAN” mode the acquisition node communication distance is 5m, Gateway node 100m, power consumption is not high, the monitoring object has a large range of motion, suitable for indoor and outdoor monitoring within 100m range; or 3.
  • " ⁇ node + long and short distance gateway node + wireless LAN ⁇ mobile network” can use free mobile network Realizing near-remote monitoring, the monitoring object can be in the indoor/outside wireless LAN communication range, and there is no global Gap care, even for indoor and outdoor field monitoring. In the above manner, the body of the monitoring object has sufficient activity and almost no constraint, for more than 24 hours, 3-18 lead real-time near-remote monitoring, and the monitoring object and the monitoring terminal can exchange information.

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Abstract

L'invention porte sur un système pour une surveillance locale/à distance à paramètres multiples basée sur des nœuds d'acquisition sans fil (V1-V6, I, II, III, avR, avL, avF) et un réseau de surface corporelle, lequel système comprend des nœuds d'acquisition (V1-V6, I, II, III, avR, avL, avF), un réseau de surface corporelle sans fil, un nœud passerelle, un réseau local sans fil et/ou câblé ou un réseau mobile, un module de communication à fréquence radio, un module d'interface homme-machine, un serveur principal, un terminal de dispositif de surveillance et l'Internet. Les nœuds d'acquisition (V1-V6, I, II, III, avR, avL, avF) acquièrent un signal électrocardiographique ou d'autres paramètres physiologiques d'un objet surveillé, qui sont transmis de manière sans fil au nœud passerelle par l'intermédiaire d'un réseau de surface corporelle, et un électrocardiogramme (ECG) est généré. Le nœud passerelle stocke ou affiche l'électrocardiogramme (ECG) ou d'autres paramètres physiologiques, ou transmet l'électrocardiogramme (ECG) ou d'autres paramètres physiologiques au serveur principal ou au terminal de dispositif de surveillance par l'intermédiaire du réseau local ou de l'Internet ou du réseau mobile, afin qu'une surveillance locale/à distance soit réalisée.
PCT/CN2010/000427 2010-04-01 2010-04-01 Système sans fil pour une surveillance en temps réel locale/à distance à paramètres multiples WO2011120203A1 (fr)

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