WO2011117289A1 - Dérivés de chromén-2-one et leur utilisation à titre d'inhibiteurs de recaptage des neurotransmetteurs monoaminés - Google Patents

Dérivés de chromén-2-one et leur utilisation à titre d'inhibiteurs de recaptage des neurotransmetteurs monoaminés Download PDF

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Publication number
WO2011117289A1
WO2011117289A1 PCT/EP2011/054431 EP2011054431W WO2011117289A1 WO 2011117289 A1 WO2011117289 A1 WO 2011117289A1 EP 2011054431 W EP2011054431 W EP 2011054431W WO 2011117289 A1 WO2011117289 A1 WO 2011117289A1
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WIPO (PCT)
Prior art keywords
disorder
pharmaceutically acceptable
compound
compound according
methyl
Prior art date
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PCT/EP2011/054431
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English (en)
Inventor
Dan Peters
Gordon Munro
Elsebet Østergaard NIELSEN
Original Assignee
Neurosearch A/S
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Publication date
Application filed by Neurosearch A/S filed Critical Neurosearch A/S
Publication of WO2011117289A1 publication Critical patent/WO2011117289A1/fr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Les présentes demandes de brevet concernent de nouveaux dérivés de 8-aza-bicyclo[3.2.1]oct-3-yloxy)- chromén-2-one et leur utilisation à titre d'inhibiteurs de recaptage des neurotransmetteurs monoaminés. Selon d'autres aspects, les présentes demandes de brevet concernent l'utilisation de ces composés dans une méthode thérapeutique et des compositions pharmaceutiques contenant les composés selon l'invention.
PCT/EP2011/054431 2010-03-25 2011-03-23 Dérivés de chromén-2-one et leur utilisation à titre d'inhibiteurs de recaptage des neurotransmetteurs monoaminés WO2011117289A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA201000247 2010-03-25
DKPA201000247 2010-03-25
US31908110P 2010-03-30 2010-03-30
US61/319,081 2010-03-30

Publications (1)

Publication Number Publication Date
WO2011117289A1 true WO2011117289A1 (fr) 2011-09-29

Family

ID=44072571

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2011/054431 WO2011117289A1 (fr) 2010-03-25 2011-03-23 Dérivés de chromén-2-one et leur utilisation à titre d'inhibiteurs de recaptage des neurotransmetteurs monoaminés

Country Status (1)

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WO (1) WO2011117289A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8697721B2 (en) 2009-05-15 2014-04-15 Aniona Aps Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997016451A1 (fr) 1995-11-02 1997-05-09 Neurosearch A/S Derives tropane condenses en tant qu'inhibiteurs de recaptage des neurotransmetteurs
WO1997030997A1 (fr) 1996-02-22 1997-08-28 Neurosearch A/S Derives du tropane, leur preparation et utilisation
WO2006035034A1 (fr) 2004-09-30 2006-04-06 Neurosearch A/S Nouveaux derives de chromene-2-one et leur utilisation comme inhibiteurs de recapture du neurotransmetteur monoamine
WO2007093604A1 (fr) 2006-02-17 2007-08-23 Neurosearch A/S Nouveaux dérivés de chromen-2-one et leurs utilisation en tant qu'inhibiteurs de recaptage d'un neuro-transmetteur monoamine

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997016451A1 (fr) 1995-11-02 1997-05-09 Neurosearch A/S Derives tropane condenses en tant qu'inhibiteurs de recaptage des neurotransmetteurs
WO1997030997A1 (fr) 1996-02-22 1997-08-28 Neurosearch A/S Derives du tropane, leur preparation et utilisation
WO2006035034A1 (fr) 2004-09-30 2006-04-06 Neurosearch A/S Nouveaux derives de chromene-2-one et leur utilisation comme inhibiteurs de recapture du neurotransmetteur monoamine
WO2007093604A1 (fr) 2006-02-17 2007-08-23 Neurosearch A/S Nouveaux dérivés de chromen-2-one et leurs utilisation en tant qu'inhibiteurs de recaptage d'un neuro-transmetteur monoamine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"Reminqton's Pharmaceutical Sciences", MAACK PUBLISHING CO.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8697721B2 (en) 2009-05-15 2014-04-15 Aniona Aps Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

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