WO2011115447A3 - Ｃ 말단이 절단된 퍼옥시레독신 ⅱ 및 이를 함유한 세포 사멸 예방 및 치료용 조성물 - Google Patents

Ｃ 말단이 절단된 퍼옥시레독신 ⅱ 및 이를 함유한 세포 사멸 예방 및 치료용 조성물 Download PDF

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Publication number
WO2011115447A3
WO2011115447A3 PCT/KR2011/001882 KR2011001882W WO2011115447A3 WO 2011115447 A3 WO2011115447 A3 WO 2011115447A3 KR 2011001882 W KR2011001882 W KR 2011001882W WO 2011115447 A3 WO2011115447 A3 WO 2011115447A3
Authority
WO
WIPO (PCT)
Prior art keywords
peroxiredoxin
preventing
composition
terminal truncated
containing same
Prior art date
Application number
PCT/KR2011/001882
Other languages
English (en)
French (fr)
Other versions
WO2011115447A9 (ko
WO2011115447A2 (ko
Inventor
채호준
최훈인
이상필
서재호
Original Assignee
(주)글로바이오텍
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by (주)글로바이오텍 filed Critical (주)글로바이오텍
Publication of WO2011115447A2 publication Critical patent/WO2011115447A2/ko
Publication of WO2011115447A3 publication Critical patent/WO2011115447A3/ko
Publication of WO2011115447A9 publication Critical patent/WO2011115447A9/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
    • C12Y111/01—Peroxidases (1.11.1)
    • C12Y111/01015—Peroxiredoxin (1.11.1.15)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Wood Science & Technology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

C 말단 아미노산이 절단된 퍼옥시레독신 Ⅱ는 전장 퍼옥시레독신 Ⅱ보다 강력한 퍼옥시다제 활성을 나타내어 산화 스트레스로 인한 세포사멸 관련 질병의 예방 및 치료용 조성물로 유용하다.
PCT/KR2011/001882 2010-03-18 2011-03-18 Ｃ 말단이 절단된 퍼옥시레독신 ⅱ 및 이를 함유한 세포 사멸 예방 및 치료용 조성물 WO2011115447A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020100024131A KR101147006B1 (ko) 2010-03-18 2010-03-18 Ｃ 말단이 절단된 퍼옥시레독신 ⅱ 및 이를 함유한 세포 사멸 예방 및 치료용 조성물
KR10-2010-0024131 2010-03-18

Publications (3)

Publication Number Publication Date
WO2011115447A2 WO2011115447A2 (ko) 2011-09-22
WO2011115447A3 true WO2011115447A3 (ko) 2012-02-23
WO2011115447A9 WO2011115447A9 (ko) 2012-03-22

Family

ID=44649735

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2011/001882 WO2011115447A2 (ko) 2010-03-18 2011-03-18 Ｃ 말단이 절단된 퍼옥시레독신 ⅱ 및 이를 함유한 세포 사멸 예방 및 치료용 조성물

Country Status (2)

Country Link
KR (1) KR101147006B1 (ko)
WO (1) WO2011115447A2 (ko)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060045902A (ko) * 2004-05-27 2006-05-17 경상대학교산학협력단 샤페론 활성을 갖는 2-시스테인 페록시레독신 고분자성결합체와 이의 용도
KR20090033749A (ko) * 2007-10-01 2009-04-06 동아대학교 산학협력단 녹두로부터 분리한 2-CYS PEROXIREDOXIN 유전자(Vrmlt63)의 염기서열, 아미노산 서열 및 유전자 기능
WO2009103312A1 (en) * 2008-02-19 2009-08-27 Ludwig-Maximilians-Universität Ezrin, serpin b5, peroxiredoxin-2 and heat shock protein beta-1 as autoantigens for psoriasis and poststreptococcal diseases

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060045902A (ko) * 2004-05-27 2006-05-17 경상대학교산학협력단 샤페론 활성을 갖는 2-시스테인 페록시레독신 고분자성결합체와 이의 용도
KR20090033749A (ko) * 2007-10-01 2009-04-06 동아대학교 산학협력단 녹두로부터 분리한 2-CYS PEROXIREDOXIN 유전자(Vrmlt63)의 염기서열, 아미노산 서열 및 유전자 기능
WO2009103312A1 (en) * 2008-02-19 2009-08-27 Ludwig-Maximilians-Universität Ezrin, serpin b5, peroxiredoxin-2 and heat shock protein beta-1 as autoantigens for psoriasis and poststreptococcal diseases

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J. C. MOON ET AL.: "Oxidative stress-dependent structural and functional switching of a human 2-Cys peroxiredoxin isotype II that enhances HeLa cell resistance to H202-induced cell death", J BIOL CHEM., vol. 280, no. 31, 2005, pages 28775 - 28784 *

Also Published As

Publication number Publication date
WO2011115447A9 (ko) 2012-03-22
WO2011115447A2 (ko) 2011-09-22
KR20110105083A (ko) 2011-09-26
KR101147006B1 (ko) 2012-05-22

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