WO2011108713A1

WO2011108713A1 - Substance discharge device

Info

Publication number: WO2011108713A1
Application number: PCT/JP2011/055098
Authority: WO
Inventors: 洋人立野
Original assignee: 国立大学法人鹿児島大学
Priority date: 2010-03-05
Filing date: 2011-03-04
Publication date: 2011-09-09
Also published as: CN102753232B; JP5305469B2; CN102753232A; JP2011182883A

Abstract

A substance discharge device (100) is provided with an oscillation unit (120) which oscillates an amplitude-modulated ultrasonic wave group obtained by modulating the amplitudes of ultrasonic waves to the surface of a discharger (200) of an excretory substance, and a control unit (130) which controls the amplitudes of the ultrasonic waves of the amplitude-modulated ultrasonic wave group oscillated by the oscillation unit (120) on the basis of the drift speed of the excretory substance with respect to the discharger (200). Consequently, the excretory substance is discharged to the outside of the discharger from the surface of the discharger such as a human body using ultrasonic oscillation, thereby achieving efficient discharge corresponding to the excretory substance.

Description

Substance discharge device

The present invention relates to a substance discharge device for discharging discharged substances from the surface of a discharged body such as a human body to the outside of the discharged body.

Currently, various techniques for achieving various purposes by applying ultrasonic vibrations on the surface of a human body or the like have been devised as cosmetic treatments.
For example, Patent Document 1 discloses a cosmetic treatment method in which skin is irradiated with ultrasonic waves to simultaneously cleanse pores and remove keratin.
Patent Document 2 discloses a cosmetic treatment method for irradiating the skin with ultrasonic waves and removing the hair at the irradiated part.

JP 2007-159950 A JP 2002-527162 A

In so-called skin care in the beauty field, for example, as a cosmetic treatment for excessive sebum (acne) and the like, phototherapy using a device such as a laser or chemical peeling is applied.
However, an ultrasonic device that treats acne using ultrasonic waves has not yet been developed.
Similarly, even when so-called drainage is performed as a surgical operation for discharging body substances such as pus, blood congested blood, and exudate out of the body, an ultrasonic device for that purpose has not been developed yet.

The present invention provides a substance discharge device that discharges discharged substances from the surface of a discharged body such as a human body to the outside of the discharged body using ultrasonic vibration and realizes efficient discharge corresponding to the discharged substance. The purpose is to provide.

The substance discharging apparatus of the present invention discharges discharged substances from the surface of the discharged body to the outside, and the amplitude is modulated so that the amplitude of each ultrasonic wave is gradually reduced with respect to the surface of the discharged body. An ultrasonic oscillator that oscillates the modulated ultrasonic wave group; and a control unit that controls the amplitude of each ultrasonic wave of the amplitude-modulated ultrasonic wave group based on the drift velocity of the discharged substance with respect to the discharged object.

According to the present invention, it is possible to discharge the discharged material from the surface of the discharged body such as a human body to the outside of the discharged body using ultrasonic vibration, and to realize efficient discharge according to the discharged material. it can.

FIG. 1 is a block diagram showing a schematic configuration of a substance discharging apparatus according to an embodiment of the present invention. FIG. 2 is a perspective view schematically showing a configuration example of the ultrasonic oscillation unit of the substance discharging apparatus according to the embodiment of the present invention. FIG. 3 is a characteristic diagram showing an amplitude-modulated ultrasonic wave group oscillated from the ultrasonic oscillator to the skin of the body to be discharged and its harmonic probability function. FIG. 4 is an equivalent circuit diagram of a dynamic model at the positive distortion amplitude of the sin wave. FIG. 5 is a schematic diagram showing the installation state of the sample used in Experiment 1. FIG. 6 is a view showing a photograph of each filter paper in which red No. 102, which is an emission material, was diffused in Example 2 and Comparative Examples 1 and 2 in Experiment 2. FIG. 7 is a characteristic diagram showing the relationship between the experiment time and the density of Red No. 102 for Samples A, B, and C in Experiment 2. FIG. 8A is a characteristic diagram showing the difference between the experimental value and approximate data for Comparative Example 1. FIG. 8B is a characteristic diagram showing the difference between the experimental value and the approximate data for Comparative Example 2. FIG. 8C is a characteristic diagram showing the difference between the experimental value and the approximate data for the example. FIG. 9 is a table showing the flow velocity J for Examples and Comparative Examples 1 and 2. FIG. 10 is a characteristic diagram showing an amplitude-modulated ultrasonic wave group that is oscillated from the vibrating part to the skin of the body to be discharged in the modification of the present embodiment.

FIG. 1 is a block diagram showing a schematic configuration of a substance discharging apparatus 100 according to an embodiment of the present invention.
As shown in FIG. 1, the substance discharging apparatus 100 includes a vibrating unit 120, a control unit 130, an information input unit 140, and a drift velocity value storage unit 150.
On the surface (skin 201) of a body to be discharged (in this embodiment, for example, a human body) 200, an exhaust material absorber 110 is disposed. The discharged substance absorber 110 absorbs discharged substances discharged from the surface, and for example, filter paper or the like is selected.

The vibration unit 120 includes, for example, a piezoelectric element (not shown) such as PZT, and each ultrasonic wave is applied to the surface (skin 201) of the discharged object 200 via the discharged substance absorber 110. An amplitude-modulated ultrasonic wave group that modulates the amplitude of is oscillated. Due to the oscillation of the amplitude-modulated ultrasonic wave group by the vibration unit 120, the discharged substance in the discharged body 200 is discharged from the skin 201 and absorbed by the discharged substance absorber 110.

As shown in FIG. 2, in the vibration unit 120, an annular vibrator 121 may be provided at a contact portion with the surface of the discharged body 200. The annular vibrator 121 has an annular flat surface at a contact portion with the discharged body 200. By providing the annular vibrator 121, a local stress gradient is generated in the portion of the annular vibrator 121 when the annular vibrator 121 is brought into contact with the surface of the discharged body 200 via the discharged substance absorber 110. In this case, the stress is low at the central portion (the central portion of the region surrounded by the annular vibrator 121) that is a non-contact portion of the vibrating portion 120 with the surface of the discharged body 200, and the discharge of exhausted substances on the surface is performed. The location is localized and the discharge efficiency is increased.

The information input unit 140 inputs, for example, various types of information including information on the type of emission material to be discharged and information on the emission amount of the emission material to the CPU 133 of the control unit 130.

The drift velocity value storage unit 150 stores a plurality of drift velocity values, and the drift velocity value storage unit 150 stores, for example, a drift velocity value for each type of discharged substance.

The control unit 130 controls the amplitude of each ultrasonic wave of the amplitude-modulated ultrasonic wave group oscillated from the vibration unit 120 based on the drift velocity of the discharged substance with respect to the discharged object 200. The control unit 130 includes an oscillation ultrasonic detection unit 131, an ultrasonic amplitude extraction unit 132, a CPU 133, an ultrasonic amplitude adjustment unit 134, a phase detection unit 135, a resonance frequency adjustment unit 136, and an AC voltage transmission unit. 137, a voltage control amplifier 138, and a power amplifier 139.

The oscillation ultrasonic detection unit 131 detects each ultrasonic wave of the amplitude-modulated ultrasonic wave group oscillated from the vibration unit 120 as a voltage value. The ultrasonic amplitude extraction unit 132 extracts the amplitude as a voltage value for each ultrasonic wave detected by the oscillation ultrasonic wave detection unit 131.

The CPU 133 controls the overall operation of the substance discharging apparatus 100. For example, the CPU 133 extracts a corresponding drift speed value from the drift speed value storage unit 150 in accordance with the type of emission material input from the information input unit 140, and based on the extracted drift speed value, the vibration unit A control signal for controlling the amplitude of the amplitude-modulated ultrasonic wave group oscillated from 120 is transmitted to the ultrasonic amplitude adjustment unit 134. Further, for example, the CPU 133 determines the number of each ultrasonic wave oscillated as one amplitude-modulated ultrasonic wave group from the vibration unit 120 based on the information related to the discharge amount of the discharged substance input from the information input unit 140, A control signal based on the determination is transmitted to the ultrasonic amplitude adjustment unit 134.

Specifically, the CPU 133 generates a control signal for controlling the amplitude of the amplitude-modulated ultrasonic group and a control signal related to the number of ultrasonic waves oscillating as the amplitude-modulated ultrasonic group as shown in FIG. Output as signal voltage. Here, each saw tooth has a linear waveform that decreases monotonously. The absolute value of the slope (inclination) of the monotonously decreasing portion of the sawtooth corresponds to the value of the extracted drift velocity, and each ultrasonic wave oscillated as one amplitude-modulated ultrasonic wave group depending on the on-time of the sawtooth. Control the number of

The ultrasonic amplitude adjustment unit 134 receives as input the voltage value related to the amplitude of each ultrasonic wave extracted by the ultrasonic amplitude extraction unit 132 and the sawtooth signal voltage from the CPU 133, and the amplitude-modulated ultrasonic wave group oscillated from the vibration unit 120. Are adjusted so that the amplitude of each ultrasonic wave is equal to or lower than the drift velocity, and a control voltage for adjusting the number of ultrasonic waves oscillated as the amplitude-modulated ultrasonic wave group is output.

The phase detection unit 135 detects the phase between the waveform of each ultrasonic wave of the amplitude-modulated ultrasonic wave group detected by the oscillation ultrasonic wave detection unit 131 and the waveform of the AC voltage output from the AC voltage transmission unit 137. The resonance frequency adjustment unit 136 controls the phase of the AC voltage output from the AC voltage transmission unit 137 based on the phase detected by the phase detection unit 135 and adjusts the vibration unit 120 to be in a resonance state. That is, the phase detection unit 135 and the resonance frequency adjustment unit 136 are based on each ultrasonic wave of the amplitude modulation ultrasonic wave group detected by the oscillation ultrasonic wave detection unit 131, and the phase difference between the ultrasonic waves of the amplitude modulation ultrasonic wave group. The “setting unit” of the present invention is configured to control the vibration unit 120 and set the vibrating unit 120 in a resonance state.

The alternating voltage transmitter 137 transmits an alternating voltage (for example, a sine wave voltage). The voltage control amplifier 138 performs control such as modulating the AC voltage transmitted from the AC voltage transmission unit 137 based on the control voltage output from the ultrasonic amplitude adjustment unit 134. The power amplification unit 139 amplifies the AC voltage modulated by the voltage control amplifier 138 and outputs the amplified voltage to the vibration unit 120.

In the vibration unit 120, the AC voltage input from the power amplification unit 139 is supplied to the above-described piezoelectric element (not shown), and distortion based on the AC voltage is generated in the piezoelectric element. Thereby, an amplitude-modulated ultrasonic wave group in which the amplitude of each ultrasonic wave is modulated is oscillated from the vibration unit 120.

Next, a substance discharging method according to the present invention in consideration of a drift speed of the discharged substance with respect to the discharge target 200 (hereinafter, this drift speed is referred to as V _d ) will be described.
FIG. 3 is a characteristic diagram showing an amplitude-modulated ultrasonic wave group oscillated from the vibrating section 120 to the skin 201 of the discharged body 200 and its harmonic probability function.

First, the amplitude-modulated ultrasonic wave group shown in FIG.
As shown in FIG. 3 (a), one amplitude-modulated ultrasonic wave group oscillated from the vibration unit 120 to the surface (skin 201) of the discharged body 200 includes a plurality of ultrasonic waves whose amplitudes are modulated. include. The number of ultrasonic waves that oscillate as one amplitude-modulated ultrasonic wave group is determined by the control unit 130 (CPU 133) based on, for example, information related to the discharge amount of the discharged substance input (set) from the information input unit 140. Is done.

Further, as shown in FIG. 3A, the control unit 130 determines the amplitude of each ultrasonic wave of the amplitude-modulated ultrasonic group with respect to the elapsed time (t) from the start of oscillation of one amplitude-modulated ultrasonic group. The amplitude of each ultrasonic wave is controlled so that the absolute value V _e of the gradient −V _e (this gradient can also be said to be the velocity at the amplitude of each ultrasonic wave with respect to the elapsed time (t)) is equal to or lower than the drift velocity V _d. To do. Here, in (a) of FIG. 3, the gradient (inclination) of the dashed line segment connecting the amplitudes of the ultrasonic waves is −V _e .

Further, as shown in FIG. 3A, the control unit 130 discharges the amplitude of each ultrasonic wave of one amplitude-modulated ultrasonic wave group from the first ultrasonic wave at the start of oscillation of the amplitude-modulated ultrasonic wave group. Control is performed to monotonously decrease to the last ultrasonic wave related to the number of ultrasonic waves oscillated determined based on the information related to the discharge amount of the substance. That is, the amplitude of each ultrasonic wave is monotonously decreased with the gradient −V _e .

Here, the ultrasonic wave in the discharge target 200 is determined by the amplitude of the first ultrasonic wave (the ultrasonic wave having the maximum amplitude among the ultrasonic waves of the amplitude-modulated ultrasonic wave group) at the start of oscillation of the amplitude-modulated ultrasonic wave group. The discharge depth is determined.
Assuming that the Young's modulus is E ₁ and E ₂ and the strain amplitudes are ε ₁ and ε ₂ for the vibrating unit 120 and the discharged body 200 that are vibrators, The stress generated by the oscillation of the sound wave is equal to the drag of the discharged object 200.

Therefore, the distortion amplitude ε ₂ of the discharged object 200, which is the discharge depth, is expressed by the following formula (2).

Therefore, the amplitude of the first ultrasonic wave at the start of oscillation of the amplitude-modulated ultrasonic wave group is a value determined according to the required discharge depth.

Further, as shown in FIG. 3A, the control unit 130 performs control on the last ultrasonic wave of one amplitude-modulated ultrasonic wave group, and then controls the next amplitude-modulated ultrasonic wave group from the vibrating unit 120. Control to perform oscillation is performed so that the shape of the amplitude-modulated ultrasonic wave group to be oscillated becomes a sawtooth shape indicated by a dashed line in FIG.

Next, the general principle relating to the harmonic probability function shown in FIG.
The flow velocity J caused in the uniform system (solid) by the external force F is expressed by the following formulas (3) and (4), where the concentration is C.

Further, the drift velocity V _d of the discharged substance with respect to the discharged object 200 is expressed as the following formula (5).

Here, as shown in the following formula (6), if the discharge by vibration stress is effective (the discharge of the discharge substance is not efficient only by the concentration gradient), and the amplitude of the vibration stress is A, the vibration stress of The amplitude A is expressed as the following formula (7).

Here, E in Equation (7) represents Young's modulus, and ε represents strain amplitude. When the velocity v of the strain amplitude ε is assumed, the wavefront x of the strain amplitude ε and the existence time Δt of x + Δx are expressed as in the following formulas (8) and (9).

Then, if the vibration period is τ, the existence probability P (x) of the wave front x of the strain amplitude ε is expressed as the following formula (10).

The existence probability P (x) shown in the equation (10) corresponds to the characteristic of the harmonic probability function shown in FIG.

On the other hand, the jumping frequency ω _j of the diffusing material gives the drift velocity V _d . When the external force frequency ω _F is in the condition shown in the following formula (11), it cannot follow the external force, and the external pressure amplitude P (x) _MAX point acts as the drift velocity acting force point.

Consider the case where PZT is used as the piezoelectric element of the vibration unit 120 and the PZT is used as a driving vibration source for discharging discharged substances. The acoustic impedance of PZT is about 34.8 × 10 ⁶ kg / m ² · s, the acoustic impedance of muscle is about 1.5 × 10 ⁶ kg / m ² · s, and the acoustic impedance of muscle is PZT. Is about 1/20 of the acoustic impedance.

Furthermore, since the acoustic vibration attenuation coefficient of the human body is about 0.15 / cm at an ultrasonic vibration frequency of 80 kHz according to experiments, the human body is regarded as a relaxation system. On the other hand, the vibration amplitude given to the human body (subject 200) by the piezoelectric element of the vibration unit 120 is limited to the positive side of the amplitude pressure function of a sine wave (sin wave). That is, only the positive side amplitude of the sin wave is given to the human body (subject 200) as a striking force. An equivalent circuit diagram of this dynamic model is shown in FIG.

The distortion positive amplitude A (t) of the sine wave shown in FIG. 4 is expressed as the following formula (12).

When this is expanded into a Fourier series, the distortion positive amplitude A (t) is expressed by the following equation (13).

Here, ε ₀ in the equation (13) is expressed as the following equation (14), and ε _{n in the} equation (13) is expressed as the following equation (15).

When the amplitude ε _n shown in Equation (15) is input to the relaxation system shown in FIG. 4, it becomes a product with the relaxation function, and ε _{n (out)} is expressed as in Equation (16) below.

Equation (16) shows that the contribution to the drift velocity V _d as a vibration term is more efficient as the drive frequency is lower. Here, Equation (14) indicates the static pressure amplitude that does not depend on the ultrasonic driving frequency ω. Then, when amplitude modulation is applied so as to have a sawtooth shape as in the amplitude-modulated ultrasonic wave group shown in FIG. 3A, Equation (14) is expressed as Equation (17) below.

Here, as described above, −V _e is the velocity at the amplitude of each ultrasonic wave of the amplitude-modulated ultrasonic wave group with respect to the elapsed time (t) from the start of oscillation of one amplitude-modulated ultrasonic wave group, that is, The inclination (gradient) of the sawtooth shape shown by the one-dot broken line in 3 (a) is shown, and the discharge condition of the discharged material must satisfy the following formula (18) as described above.

It is assumed that the diffusion activation potential of the discharged substance in the discharged object 200 is U and the diffusion coefficient of the discharged substance is D. The diffusion coefficient D is proportional to the movement probability when moving to the adjacent site (distance under external force Δx) in the discharged object 200 by changing the diffusion activation potential U.
Further, when the force per distance Δx under the external force is F, the decrease potential ΔU and the diffusion coefficient _DF are expressed by equations (19) and (20).

Therefore, the diffusion coefficient D _F of solute concentration C along the rod-shaped sample is increased due to an external force than the diffusion coefficient D ₀ of the external force is zero. When C ₀ is a diffusion concentration with an infinite time, C under an external force is expressed by Equation (21).

Based on Equation (21), the time dependence of the concentration at a fixed point is as shown in Equations (22) and (23) below.

Next, various experimental results using the substance discharging apparatus according to the embodiment of the present invention will be described.

(Experiment 1)
In Experiment 1, the relationship between the discharged material and the drift velocity with respect to the discharged object 200 was examined.
In the experiment, as shown in FIG. 5, agar 111 was used as the discharge target 200, and three types having different molecular weights were prepared as equivalent to the discharged substances. Specifically, sample 1 was used in which agar 111 was impregnated with red No. 102 (molecular weight 631.51), which is a coloring agent, as an emission material. Sample 2 was prepared by impregnating Agar 111 with Blue No. 1 (molecular weight 792.86), which is a coloring agent, as an emission material. Sample 2 was prepared by impregnating agar 111 with a drug insulin (molecular weight 5807) as an excretion substance.

The vibration unit 120 is arranged under the agar 111 via the filter paper which is the emission material absorber 110 of FIG. 1, and the weight 112 is placed on the agar 111 so that the ultrasonic vibration can be easily transmitted to the agar 111. In this state, ultrasonic waves were sequentially oscillated in the agar 111 by the vibration unit 120. By changing the oscillation frequency of the ultrasonic wave, the relationship between the oscillation frequency and the concentration of the discharged substance absorbed by the filter paper from each sample was examined. As a result, it was found that each sample draws different curves in relation to the oscillation frequency of ultrasonic amplitude modulation and the concentration of the discharged substance. From the above, it was confirmed that each emission material has a unique drift velocity corresponding to its molecular weight in relation to the non-emission material.

(Experiment 2)
In Experiment 2, based on the comparison with the comparative example, the superiority of the discharge of discharged substances by the discharge apparatus according to the present embodiment was examined.
In the experiment, as in FIG. 5, the discharged object 200 was made by soaking agar No. 102, which is a coloring agent, into the agar 111. Under the agar 111, the vibrating unit 120 was disposed via the filter paper which is the exhaust material absorber 110 of FIG. 1, and the weight 112 was placed on the agar 111. In this state, as an example, an amplitude-modulated ultrasonic wave having a sawtooth shape with a negative gradient was oscillated on the agar 111 by the vibration unit 120. Further, for comparison with the example, the filter paper was placed under the agar 111, and the weight 112 was placed on the agar 111, and the comparative example 1 in which red No. 102 was naturally diffused to the filter paper only by the concentration gradient. 5 and Comparative Example 2 in which ultrasonic waves having a fixed amplitude were oscillated in the agar 111 in the same state as in FIG.

FIG. 6 is a view showing a photograph of each filter paper in which red No. 102, which is an emission material, was diffused in Example 2 and Comparative Examples 1 and 2 in Experiment 2.
In FIG. 6, sample A is a filter paper left by natural diffusion of Comparative Example 1 for 3 minutes, sample B is a filter paper that oscillates a fixed-amplitude ultrasonic wave of Comparative Example 2 for 3 minutes, and sample C is a negative-gradient sawtooth according to the example. This is a filter paper in which amplitude-modulated ultrasonic waves having a shape are oscillated for 3 minutes with a vibration period of 0.1 seconds.
As is apparent from the photograph in FIG. 6, the density difference of red No. 102 is small between sample A and sample B, but the density of red No. 102 is very high in sample C compared to samples A and B.

Subsequently, for samples A, B, and C, the relationship between the experiment time and the density of Red No. 102 was examined. The experimental results are shown in FIG.
In FIG. 7, the test time (sample A, the standing time, and samples B and C, the ultrasonic oscillation time) is 60 seconds, 120 seconds, 180 seconds, 300 seconds, 600 seconds, and sample A, Each filter paper of B and C was dissolved in distilled water, and the absorbance (Abs) was measured with a spectroscope. The approximate data in FIG. 7 is the absorbance calculated based on the mathematical formulas (22) and (23).
From the experimental results of FIG. 7, it was confirmed that the sample C of the example showed higher absorbance than the samples A and B of the comparative examples 1 and 2.

The differences between the experimental values and the approximate data for the examples and comparative examples 1 and 2 are shown in FIGS. 8A to 8C. FIG. 8A is Comparative Example 1, and the approximate data is absorbance obtained from consideration of natural diffusion. FIG. 8B is Comparative Example 2, and the approximate data is the absorbance obtained from consideration when the ultrasonic wave is set to a fixed amplitude. FIG. 8C is an example, and the approximate data is the absorbance calculated based on Equations (22) and (23).
The probability error in each example is 1 ± 0.141 in Comparative Example 1 in FIG. 8A, 1 ± 0.017 in Comparative Example 2 in FIG. 8B, and 1 ± 0.004 in the Example in FIG. 8C. From this result, it was confirmed that the probability error was extremely small in the example as compared with Comparative Examples 1 and 2.

Using Equation (21), the result of Experiment 2 can be analyzed by the method of least squares.
Based on the result of the experiment 1 described above, the value of the coefficient a can be calculated by using the nonlinear least square method.
From the calculated coefficient a, Comparative Example 1 using only a concentration gradient, Comparative Example 2 using a fixed-amplitude ultrasonic wave, and using a negative-gradient sawtooth-shaped amplitude-modulated ultrasonic wave according to this embodiment For each example, the value of flow velocity J was calculated. The result is shown in FIG. In FIG. 9, the flow velocity J in the case of only the concentration gradient is set as the reference value 1, and the flow velocity J in the comparative example 2 and the example is set as the relative value. In the examples, a flow rate about twice that of Comparative Examples 1 and 2 was obtained. From this, the effectiveness of the discharge of the discharged substance using the amplitude-modulated ultrasonic wave of the sawtooth shape having a negative gradient according to the present embodiment was confirmed.
That is, it is more efficient to supply the amplitude-modulated ultrasonic group in consideration of the drift velocity (−V _d ) than the natural diffusion due to the concentration gradient or the continuous supply of the fixed-amplitude ultrasonic wave. It was proved that emission can be realized.

As described above, according to the present embodiment, the amplitude of each ultrasonic wave of the amplitude-modulated ultrasonic wave group oscillated from the vibration unit 120 is controlled based on the drift velocity −V _d of the discharged substance with respect to the discharged object 200. Since it did in this way, when discharging | emitting waste material from the surface of to-be-discharged bodies, such as a human body, using an ultrasonic wave, the efficient discharge | emission according to the said discharge | release material is implement | achieved.
The substance discharge device of the present invention can be applied, for example, to the treatment of efficiently removing sebum, which is the content of acne, as a discharge substance, or discharges bodily substances such as pus, congested blood, and exudate out of the body. As a surgical operation, it can be applied to so-called drainage.

In the present embodiment, the control unit 130 controls the amplitude of each ultrasonic wave of the amplitude-modulated ultrasonic wave group oscillated from the vibration unit 120 based on the information related to the discharged substance input from the information input unit 140 and one The number of ultrasonic waves oscillated as an amplitude-modulated ultrasonic wave group is controlled. However, the present invention is not limited to this. For example, the information related to the discharged substances shown in this embodiment is used. In addition, the information related to the measured acoustic impedance of the discharged object 200 is input from the information input unit 140, and the amplitude oscillated from the vibration unit 120 in addition to the information related to the discharged substance in addition to the information related to the acoustic impedance. It may be configured to control the amplitude of each ultrasonic wave in the modulated ultrasonic wave group and the number of ultrasonic waves oscillated as one amplitude modulated ultrasonic wave group.

(Modification)
Hereinafter, modifications of the present embodiment will be described. In this modification, a substance discharging apparatus having the same apparatus configuration as that of FIG. 1 of the present embodiment is disclosed, but is different from the present embodiment in that the oscillation state of the amplitude-modulated ultrasonic wave group is slightly different.

FIG. 10 is a characteristic diagram showing an amplitude-modulated ultrasonic wave group that is oscillated from the ultrasonic oscillator to the skin of the body to be discharged. The diffusion of the discharged substance (diffusion of the discharged body from the skin to the outside) is a linear combination of the natural diffusion and the external force diffusion by the ultrasonic wave oscillated as the amplitude-modulated ultrasonic wave group from the vibration unit 120. The diffusion depth based only on the concentration gradient due to natural diffusion is expressed by the following formula (24).

In this modification, the control unit 130 adds the contribution of the above natural diffusion to the external force diffusion by the ultrasonic waves oscillated from the vibration unit 120 as the amplitude-modulated ultrasonic wave group, and the oscillation order of each amplitude-modulated ultrasonic wave group having a negative gradient. Oscillation is controlled so that the amplitude increases every time.
In this way, by controlling the oscillation of each amplitude-modulated ultrasonic group, the amplitude of the amplitude-modulated ultrasonic group is small at the beginning of oscillation, so the number of discharged substances transferred due to the drift speed per unit time increases, Increases the number of sweeps of emissions to the surface. As a result, the discharge efficiency of the discharged substances is further improved.

In addition, in this embodiment and the modification, although demonstrated supposing the human body as the to-be-discharged body 200, in this invention, it is not necessarily limited to this and can apply also to another animal.
Furthermore, it is also possible to apply the substance discharging apparatus of the present invention to stain removal of clothes and the like by using a body to be discharged other than a living body, for example, clothes and the like, and using stains on clothes and the like as discharge substances.

1 can be realized by operating a program stored in a RAM, a ROM, or the like of a computer. This program and a computer-readable storage medium storing the program are included in the present invention.

Specifically, the program is recorded on a storage medium such as a CD-ROM, or provided to a computer via various transmission media. As a storage medium for recording the program, a flexible disk, a hard disk, a magnetic tape, a magneto-optical disk, a nonvolatile memory card, or the like can be used in addition to the CD-ROM. On the other hand, as the transmission medium of the program, a communication medium in a computer network (LAN, WAN such as the Internet, wireless communication network, etc.) system for propagating and supplying program information as a carrier wave can be used. In addition, examples of the communication medium at this time include a wired line such as an optical fiber, a wireless line, and the like.

Moreover, not only the function of the substance discharging apparatus 100 according to the present embodiment is realized by executing a program supplied by the computer, but also an OS (Operating System) or other application in which the program is running on the computer. When the function of the substance discharging apparatus 100 according to the present embodiment is realized in cooperation with software or the like, or all or part of the processing of the supplied program is performed by a function expansion board or a function expansion unit of the computer. Such a program is also included in the present invention when the function of the substance discharging apparatus 100 according to the present embodiment is realized.

Claims

A substance discharge device for discharging discharged substances from the surface of the discharged body to the outside,
An ultrasonic oscillator that oscillates an amplitude-modulated ultrasonic wave group that is modulated so as to gradually reduce the amplitude of each ultrasonic wave with respect to the surface of the discharged object;
And a control unit that controls the amplitude of each ultrasonic wave of the amplitude-modulated ultrasonic wave group based on a drift velocity of the discharged substance with respect to the discharged object.
The control unit is configured so that an absolute value of an amplitude gradient in each ultrasonic wave of the amplitude-modulated ultrasonic wave group with respect to an elapsed time from the start of oscillation of the amplitude-modulated ultrasonic wave group is equal to or less than the drift velocity. 2. The substance discharging apparatus according to claim 1, wherein the amplitude of the ultrasonic wave is controlled.
2. The substance discharging apparatus according to claim 1, wherein the control unit determines the number of the respective ultrasonic waves that oscillate as the amplitude-modulated ultrasonic wave group according to a set discharge amount of the discharged substance. .
The control unit determines the amplitude of each ultrasonic wave of the amplitude-modulated ultrasonic wave group from the first ultrasonic wave at the start of oscillation of the amplitude-modulated ultrasonic wave group according to the determined number of ultrasonic waves to be oscillated. The substance discharging apparatus according to claim 3, wherein control is performed so as to monotonously decrease.
The control unit performs control for oscillating the next amplitude-modulated ultrasonic wave group from the ultrasonic wave oscillating unit after performing control on the last ultrasonic wave of the amplitude-modulated ultrasonic wave group. 5. The substance discharging apparatus according to claim 4, wherein the sound wave group is controlled so as to have a sawtooth shape having a negative gradient.
6. The substance discharging apparatus according to claim 5, wherein the control unit controls the amplitude to increase for each oscillation order of the amplitude-modulated ultrasonic groups.
2. The substance discharging apparatus according to claim 1, wherein the ultrasonic wave oscillating portion has an annular vibrator at a contact portion with the surface of the discharged body.
A storage unit for storing a value of the drift velocity for each type of the emission substance;
And at least an information input unit for inputting information relating to the type of the substance to be actually discharged,
The control unit extracts a corresponding drift velocity value from the storage unit according to the type of the emission material input from the information input unit, and the amplitude-modulated ultrasonic wave based on the extracted drift velocity value The substance discharging apparatus according to claim 1, wherein the group amplitude is controlled.
The control unit detects a respective ultrasonic wave of the amplitude-modulated ultrasonic wave group oscillated from the ultrasonic wave oscillating unit, and the amplitude-modulated ultrasonic wave based on the ultrasonic wave detected by the detection unit. The substance discharging apparatus according to claim 1, further comprising: a setting unit that controls a phase difference of each ultrasonic wave of the sound wave group to set the ultrasonic wave oscillation unit in a resonance state.