WO2011103182A3 - Imaging methods for assessment and quantification of vaccination and in vivo antigen capture - Google Patents

Imaging methods for assessment and quantification of vaccination and in vivo antigen capture Download PDF

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Publication number
WO2011103182A3
WO2011103182A3 PCT/US2011/025072 US2011025072W WO2011103182A3 WO 2011103182 A3 WO2011103182 A3 WO 2011103182A3 US 2011025072 W US2011025072 W US 2011025072W WO 2011103182 A3 WO2011103182 A3 WO 2011103182A3
Authority
WO
WIPO (PCT)
Prior art keywords
vaccination
quantification
assessment
imaging methods
antigen capture
Prior art date
Application number
PCT/US2011/025072
Other languages
French (fr)
Other versions
WO2011103182A2 (en
Inventor
Jeff Bulte
Christopher Long
Hyam Levitsky
Original Assignee
The Johns Hopkins University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Johns Hopkins University filed Critical The Johns Hopkins University
Publication of WO2011103182A2 publication Critical patent/WO2011103182A2/en
Publication of WO2011103182A3 publication Critical patent/WO2011103182A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/586—Liposomes, microcapsules or cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/12—Measuring magnetic properties of articles or specimens of solids or fluids
    • G01R33/1269—Measuring magnetic properties of articles or specimens of solids or fluids of molecules labeled with magnetic beads

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention provides for labeling, imaging, and quantifying an antigen presenting cell in vivo.
PCT/US2011/025072 2010-02-16 2011-02-16 Imaging methods for assessment and quantification of vaccination and in vivo antigen capture WO2011103182A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30505610P 2010-02-16 2010-02-16
US61/305,056 2010-02-16

Publications (2)

Publication Number Publication Date
WO2011103182A2 WO2011103182A2 (en) 2011-08-25
WO2011103182A3 true WO2011103182A3 (en) 2011-12-29

Family

ID=44483546

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/025072 WO2011103182A2 (en) 2010-02-16 2011-02-16 Imaging methods for assessment and quantification of vaccination and in vivo antigen capture

Country Status (1)

Country Link
WO (1) WO2011103182A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ307995B6 (en) * 2015-05-26 2019-10-09 Mendelova Univerzita V Brně Using superparamagnetic particles modified with samarium, gadolinium or yttrium for detection of the ebola virus

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030232399A1 (en) * 2000-06-14 2003-12-18 Robertson John Forsyth Russell Cancer detection methods and reagents
WO2008144028A1 (en) * 2007-05-14 2008-11-27 The Johns Hopkins University Methods for in vivo imaging of cells
WO2009002529A2 (en) * 2007-06-26 2008-12-31 The Johns Hopkins University Labeled inhibitors of prostate specific membrane antigen (psma), biological evaluation, and use as imaging agents

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030232399A1 (en) * 2000-06-14 2003-12-18 Robertson John Forsyth Russell Cancer detection methods and reagents
WO2008144028A1 (en) * 2007-05-14 2008-11-27 The Johns Hopkins University Methods for in vivo imaging of cells
WO2009002529A2 (en) * 2007-06-26 2008-12-31 The Johns Hopkins University Labeled inhibitors of prostate specific membrane antigen (psma), biological evaluation, and use as imaging agents

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
AHRENS, E. T. ET AL.: "Receptor-mediated endocytosis of iron-oxide particles provides dfficient labeling of dendritic cells for in vivo MR imaging.", MAGN. RESON. MED., vol. 49, June 2003 (2003-06-01), pages 1006 - 1013 *
ROGERS, W. J. ET AL.: "Technology insight: in vivo cell tracking by use of MRI.", NAT. CLIN. PRACT. CARDIOVASC. MED., vol. 3, no. 10, October 2006 (2006-10-01), pages 554 - 562 *
WU, Y. J. ET AL.: "In vivo leukocyte labeling with intravenous ferumoxides/protamine sulfate complex and in vitro characterization for cellular magnetic resonance imaging.", AM. J. PHYSOL. CELL PHYSIOL., vol. 393, 26 September 2007 (2007-09-26), pages C1698 - C1708 *

Also Published As

Publication number Publication date
WO2011103182A2 (en) 2011-08-25

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