WO2011093819A3 - Nouvelle composition pharmaceutique combinée comprenant du tiotropium - Google Patents

Nouvelle composition pharmaceutique combinée comprenant du tiotropium Download PDF

Info

Publication number
WO2011093819A3
WO2011093819A3 PCT/TR2011/000021 TR2011000021W WO2011093819A3 WO 2011093819 A3 WO2011093819 A3 WO 2011093819A3 TR 2011000021 W TR2011000021 W TR 2011000021W WO 2011093819 A3 WO2011093819 A3 WO 2011093819A3
Authority
WO
WIPO (PCT)
Prior art keywords
tiotropium
pharmaceutical combination
new pharmaceutical
ciclesonide
copd
Prior art date
Application number
PCT/TR2011/000021
Other languages
English (en)
Other versions
WO2011093819A2 (fr
Inventor
Mahmut Bilgic
Original Assignee
Mahmut Bilgic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mahmut Bilgic filed Critical Mahmut Bilgic
Publication of WO2011093819A2 publication Critical patent/WO2011093819A2/fr
Publication of WO2011093819A3 publication Critical patent/WO2011093819A3/fr
Priority to US13/531,972 priority Critical patent/US8834931B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention concerne une composition pharmaceutique comprenant du bromure de tiotropium, du fumarate de formotérol et du ciclésonide, et son utilisation dans le traitement symptomatique et/ou prophylactique de maladies respiratoires, notamment l'asthme, la rhinite allergique, la bronchopneumopathie chronique obstructive (BPCO).
PCT/TR2011/000021 2009-12-25 2011-01-28 Nouvelle composition pharmaceutique combinée comprenant du tiotropium WO2011093819A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US13/531,972 US8834931B2 (en) 2009-12-25 2012-06-25 Dry powder formulation containing tiotropium for inhalation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2010/00623A TR201000623A2 (tr) 2010-01-28 2010-01-28 Yeni tiotropyum kombinasyonu.
TR2010/00623 2010-01-28

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2011/000022 Continuation-In-Part WO2011093820A2 (fr) 2009-12-25 2011-01-28 Composition pharmaceutique combinée comprenant du tiotropium

Related Child Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2011/000019 Continuation-In-Part WO2011093817A1 (fr) 2009-12-25 2011-01-28 Compositions pharmaceutiques comprenant du tiotropium, du formotérol et du budésonide

Publications (2)

Publication Number Publication Date
WO2011093819A2 WO2011093819A2 (fr) 2011-08-04
WO2011093819A3 true WO2011093819A3 (fr) 2012-02-23

Family

ID=43898675

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2011/000021 WO2011093819A2 (fr) 2009-12-25 2011-01-28 Nouvelle composition pharmaceutique combinée comprenant du tiotropium

Country Status (2)

Country Link
TR (1) TR201000623A2 (fr)
WO (1) WO2011093819A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013109216A2 (fr) * 2012-01-16 2013-07-25 Mahmut Bilgic Préparation de formulations en poudre sèche comprenant du tiotropium
WO2013109212A1 (fr) * 2012-01-16 2013-07-25 Mahmut Bilgic Formulations en poudre sèche comprenant de la ciclésonide
EP2804590A1 (fr) * 2012-01-16 2014-11-26 Mahmut Bilgic Formulations en poudre sèche comprenant du tiotropium et du carmotérol
WO2014007773A1 (fr) * 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Compositions comprenant un antagoniste du récepteur muscarinique et du sorbitol
EA036153B1 (ru) * 2012-07-05 2020-10-06 Арвен Айлак Санайи Ве Тиджарет А.С. Фармацевтическая композиция для ингаляции, упакованная дозированная форма, капсула, способ лечения обструктивных заболеваний дыхательных путей и фармацевтический набор
WO2014007769A1 (fr) * 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Compositions comprenant un antagoniste du récepteur muscarinique et du glucose anhydre
US10105316B2 (en) * 2012-07-05 2018-10-23 Arven llac Sanayi Ve Ticaret A.S. Inhalation compositions comprising muscarinic receptor antagonist
US10111957B2 (en) 2012-07-05 2018-10-30 Arven Ilac Snayi ve Ticaret A.S. Inhalation compositions comprising glucose anhydrous
TR201712424A2 (tr) * 2017-08-21 2019-03-21 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Kuru toz i̇nhalasyon bi̇leşi̇mleri̇

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004019985A1 (fr) * 2002-08-29 2004-03-11 Cipla Ltd Produits et compositions pharmaceutiques comprenant des agents anticholinergiques specifiques, des agonistes beta-2 et des corticosteroides
WO2008102128A2 (fr) * 2007-02-19 2008-08-28 Cipla Limited Combinaisons pharmaceutiques
US20090188497A1 (en) * 2003-12-03 2009-07-30 Boehringer Ingelheim International Gmbh Medical product containing tiotropium

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004019985A1 (fr) * 2002-08-29 2004-03-11 Cipla Ltd Produits et compositions pharmaceutiques comprenant des agents anticholinergiques specifiques, des agonistes beta-2 et des corticosteroides
US20090188497A1 (en) * 2003-12-03 2009-07-30 Boehringer Ingelheim International Gmbh Medical product containing tiotropium
WO2008102128A2 (fr) * 2007-02-19 2008-08-28 Cipla Limited Combinaisons pharmaceutiques

Also Published As

Publication number Publication date
TR201000623A2 (tr) 2011-08-22
WO2011093819A2 (fr) 2011-08-04

Similar Documents

Publication Publication Date Title
WO2011093819A3 (fr) Nouvelle composition pharmaceutique combinée comprenant du tiotropium
WO2011093820A3 (fr) Composition pharmaceutique combinée comprenant du tiotropium
WO2006117300A3 (fr) Formes cristallines de bromure de tiotropium
EP2749280A3 (fr) Composition pharmaceutique de glycopyrronium et formotérol
WO2006117299A3 (fr) Formes cristallines de bromure de tiotropium
TR201000680A2 (tr) Tiotropyum, formoterol ve budesonid içeren farmasötik bileşimler
CA2897464C (fr) Procedes de traitement de troubles auto-immuns, respiratoires et inflammatoires par inhalation de n-oxyde de roflumilast
WO2014016548A3 (fr) Composition pharmaceutique
WO2012016889A3 (fr) Formulation de poudre sèche comprenant un inhibiteur de phosphodiestérase
WO2010094731A3 (fr) Composition pharmaceutique a inhaler
IL213959A (en) Inhaled corticosteroid gas fog spray for use in the treatment of patients with severe and uncontrolled asthma
NZ629920A (en) A method for making an inhalable pharmaceutical composition using a resonant acoustic blender
WO2009134524A3 (fr) Procédé et système permettant de traiter la bronchopneumopathie chronique obstructive au moyen d'administrations d'anticholinergiques par nébulisation
EP2411003A4 (fr) Utilisation de dérivés de l'artémisinine dans le traitement de l'asthme et de la broncho-pneumopathie obstructive chronique (bpco)
TR201000681A2 (tr) İnhalasyon yoluyla alınan kuru toz formülasyonları.
MY146628A (en) Novel crystalline anhydride with anticholinergic effect
IL199022A0 (en) A combination of compounds, which can be used in the treatment of respiratory diseases, especially chronic obstructive pulmonary disease (copd) and asthma
WO2007099329A3 (fr) Formulation pour pulvérisateur
EP2120935A4 (fr) Nouvelle combinaison de composés utilisés dans le traitement des maladies des voies aériennes, en particulier la bronchopneumopathie chronique obstructive (copd) et l'asthme
EA201201397A1 (ru) Ингалятор, содержащий расслаиваемую блистерную упаковку
EA201201392A1 (ru) Кнопочное устройство мундштука ингалятора сухого порошка
WO2012014165A8 (fr) Procédé de traitement d'une affection broncho-constrictrice
WO2015049519A3 (fr) Procédé et appareil
UA115989C2 (uk) Фармацевтична композиція для інгалятора сухого порошку, що містить антагоністи мускаринових рецепторів тривалої дії
MX368036B (es) Particulas inhalables que comprenden tiotropio e indacaterol.

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 11706046

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 11706046

Country of ref document: EP

Kind code of ref document: A2