WO2011088044A3 - Prime/proxy model enhancement - Google Patents

Prime/proxy model enhancement Download PDF

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Publication number
WO2011088044A3
WO2011088044A3 PCT/US2011/020835 US2011020835W WO2011088044A3 WO 2011088044 A3 WO2011088044 A3 WO 2011088044A3 US 2011020835 W US2011020835 W US 2011020835W WO 2011088044 A3 WO2011088044 A3 WO 2011088044A3
Authority
WO
WIPO (PCT)
Prior art keywords
prime
proxy model
model enhancement
enhancement
proxy
Prior art date
Application number
PCT/US2011/020835
Other languages
French (fr)
Other versions
WO2011088044A2 (en
Inventor
Karl Wassmann
Jay Magidson
Original Assignee
Source Mdx
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Source Mdx filed Critical Source Mdx
Publication of WO2011088044A2 publication Critical patent/WO2011088044A2/en
Publication of WO2011088044A3 publication Critical patent/WO2011088044A3/en

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/30—Unsupervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G16B5/20—Probabilistic models
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Data Mining & Analysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Biophysics (AREA)
  • Evolutionary Computation (AREA)
  • Software Systems (AREA)
  • Public Health (AREA)
  • Artificial Intelligence (AREA)
  • Bioethics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Probability & Statistics with Applications (AREA)
  • Physiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention provides methods for identifying models useful for predicting a biological state of a subject.
PCT/US2011/020835 2010-01-12 2011-01-11 Prime/proxy model enhancement WO2011088044A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29438610P 2010-01-12 2010-01-12
US61/294,386 2010-01-12

Publications (2)

Publication Number Publication Date
WO2011088044A2 WO2011088044A2 (en) 2011-07-21
WO2011088044A3 true WO2011088044A3 (en) 2011-11-17

Family

ID=44304928

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/020835 WO2011088044A2 (en) 2010-01-12 2011-01-11 Prime/proxy model enhancement

Country Status (1)

Country Link
WO (1) WO2011088044A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10319477B1 (en) * 2017-03-08 2019-06-11 Virta Health Corp. Dynamic data-driven biological state analysis

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020019704A1 (en) * 2000-05-04 2002-02-14 Tusher Virginia Goss Significance analysis of microarrays
US20030014232A1 (en) * 2001-05-22 2003-01-16 Paterson Thomas S. Methods for predicting biological activities of cellular constituents
US20040254736A1 (en) * 2003-06-13 2004-12-16 Michelson Seth Gary Predictive toxicology for biological systems
US20050130192A1 (en) * 2003-09-11 2005-06-16 Paterson Thomas S. Apparatus and method for identifying therapeutic targets using a computer model

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020019704A1 (en) * 2000-05-04 2002-02-14 Tusher Virginia Goss Significance analysis of microarrays
US20030014232A1 (en) * 2001-05-22 2003-01-16 Paterson Thomas S. Methods for predicting biological activities of cellular constituents
US20040254736A1 (en) * 2003-06-13 2004-12-16 Michelson Seth Gary Predictive toxicology for biological systems
US20050130192A1 (en) * 2003-09-11 2005-06-16 Paterson Thomas S. Apparatus and method for identifying therapeutic targets using a computer model

Also Published As

Publication number Publication date
WO2011088044A2 (en) 2011-07-21

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