WO2011073995A3 - Liquid vaginal spray of progesterone - Google Patents
Liquid vaginal spray of progesterone Download PDFInfo
- Publication number
- WO2011073995A3 WO2011073995A3 PCT/IN2010/000790 IN2010000790W WO2011073995A3 WO 2011073995 A3 WO2011073995 A3 WO 2011073995A3 IN 2010000790 W IN2010000790 W IN 2010000790W WO 2011073995 A3 WO2011073995 A3 WO 2011073995A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- progesterone
- vaginal spray
- liquid vaginal
- liquid
- solvent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
Abstract
Disclosed herein a liquid vaginal spray composition comprising natural/synthetic progesterone along with unique blend of solvent/co-solvent and anti-oxidants useful for treating secondary amenorrhea, threatened or habitual abortions and infertility.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2879MU2009 | 2009-12-14 | ||
IN2879/MUM/2009 | 2009-12-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2011073995A2 WO2011073995A2 (en) | 2011-06-23 |
WO2011073995A3 true WO2011073995A3 (en) | 2011-08-11 |
Family
ID=43971502
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IN2010/000790 WO2011073995A2 (en) | 2009-12-14 | 2010-12-06 | Liquid vaginal spray of progesterone |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2011073995A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9248136B2 (en) | 2011-11-23 | 2016-02-02 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
KR20170005819A (en) | 2014-05-22 | 2017-01-16 | 쎄러퓨틱스엠디, 인코퍼레이티드 | Natural combination hormone replacement formulations and therapies |
JP2017523138A (en) | 2014-07-29 | 2017-08-17 | セラピューティックスエムディー インコーポレーテッドTherapeuticsmd, Inc. | Transdermal cream |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
AU2017239645A1 (en) | 2016-04-01 | 2018-10-18 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4252787A (en) * | 1976-12-27 | 1981-02-24 | Cambridge Research And Development Group | Anti-fertility composition and method |
US20050181045A1 (en) * | 1998-11-18 | 2005-08-18 | Ferring Pharmaceuticals, Inc. | Vaginally administrable progesterone-containing tablets and method for preparing same |
WO2006060462A1 (en) * | 2004-12-01 | 2006-06-08 | Johnson & Johnson Consumer Companies, Inc. | Compositions and methods of treating irritation and kit therefor |
WO2006131784A1 (en) * | 2004-04-28 | 2006-12-14 | Foamix Ltd. | Body cavity foams |
WO2008154240A1 (en) * | 2007-06-06 | 2008-12-18 | Biohealth Llc | Pharmaceutical composition of a new system for vaginal release of steroids |
WO2009101182A1 (en) * | 2008-02-15 | 2009-08-20 | N.V. Organon | Use of etonogestrel for benign prostate hyperplasia (bph). |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2747042B1 (en) | 1996-04-05 | 1998-06-05 | Besins Iscovesco Lab | PROGESTERONE AND OESTRADIOL-BASED MEDICINE |
US20040198706A1 (en) | 2003-03-11 | 2004-10-07 | Carrara Dario Norberto R. | Methods and formulations for transdermal or transmucosal application of active agents |
-
2010
- 2010-12-06 WO PCT/IN2010/000790 patent/WO2011073995A2/en active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4252787A (en) * | 1976-12-27 | 1981-02-24 | Cambridge Research And Development Group | Anti-fertility composition and method |
US20050181045A1 (en) * | 1998-11-18 | 2005-08-18 | Ferring Pharmaceuticals, Inc. | Vaginally administrable progesterone-containing tablets and method for preparing same |
WO2006131784A1 (en) * | 2004-04-28 | 2006-12-14 | Foamix Ltd. | Body cavity foams |
WO2006060462A1 (en) * | 2004-12-01 | 2006-06-08 | Johnson & Johnson Consumer Companies, Inc. | Compositions and methods of treating irritation and kit therefor |
WO2008154240A1 (en) * | 2007-06-06 | 2008-12-18 | Biohealth Llc | Pharmaceutical composition of a new system for vaginal release of steroids |
WO2009101182A1 (en) * | 2008-02-15 | 2009-08-20 | N.V. Organon | Use of etonogestrel for benign prostate hyperplasia (bph). |
Non-Patent Citations (2)
Title |
---|
SITRUK-WARE ET AL: "Reprint of Pharmacological profile of progestins", MATURITAS, ELSEVIER SCIENCE PUBLISHERS IRELAND LTD, IR, vol. 61, no. 1-2, 1 September 2008 (2008-09-01), pages 151 - 157, XP025742124, ISSN: 0378-5122, [retrieved on 20081117], DOI: DOI:10.1016/J.MATURITAS.2008.11.011 * |
SKOUBY S O ET AL: "Progestins in HRT: Sufferance or desire?", MATURITAS, ELSEVIER SCIENCE PUBLISHERS IRELAND LTD, IR, vol. 62, no. 4, 20 April 2009 (2009-04-20), pages 371 - 375, XP026058465, ISSN: 0378-5122, [retrieved on 20090208], DOI: DOI:10.1016/J.MATURITAS.2008.12.019 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9248136B2 (en) | 2011-11-23 | 2016-02-02 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
Also Published As
Publication number | Publication date |
---|---|
WO2011073995A2 (en) | 2011-06-23 |
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