WO2011063195A3 - Purification of modified cytokines - Google Patents

Purification of modified cytokines Download PDF

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Publication number
WO2011063195A3
WO2011063195A3 PCT/US2010/057364 US2010057364W WO2011063195A3 WO 2011063195 A3 WO2011063195 A3 WO 2011063195A3 US 2010057364 W US2010057364 W US 2010057364W WO 2011063195 A3 WO2011063195 A3 WO 2011063195A3
Authority
WO
WIPO (PCT)
Prior art keywords
purification
cytokines
modified cytokines
modified
methods
Prior art date
Application number
PCT/US2010/057364
Other languages
French (fr)
Other versions
WO2011063195A2 (en
Inventor
Darshan Koticha
Aniket B. Chaudhari
Kishore Jahagirdar
Original Assignee
Dr. Reddy's Laboratories Ltd.
Dr. Reddy's Laboratories, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr. Reddy's Laboratories Ltd., Dr. Reddy's Laboratories, Inc. filed Critical Dr. Reddy's Laboratories Ltd.
Publication of WO2011063195A2 publication Critical patent/WO2011063195A2/en
Publication of WO2011063195A3 publication Critical patent/WO2011063195A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Methods for purifying modified cytokines. A process includes the use of a cation exchange chromatographic technique for the purification of a desired cytokine. The purified cytokines can be used in therapeutic compositions.
PCT/US2010/057364 2009-11-20 2010-11-19 Purification of modified cytokines WO2011063195A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2853CH2009 2009-11-20
IN2853/CHE/2009 2009-11-20

Publications (2)

Publication Number Publication Date
WO2011063195A2 WO2011063195A2 (en) 2011-05-26
WO2011063195A3 true WO2011063195A3 (en) 2011-11-24

Family

ID=44060355

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/057364 WO2011063195A2 (en) 2009-11-20 2010-11-19 Purification of modified cytokines

Country Status (1)

Country Link
WO (1) WO2011063195A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8853150B2 (en) 2010-07-29 2014-10-07 Eleven Biotherapeutics, Inc. Chimeric IL-1 receptor type I antagonists
SG10201606218WA (en) * 2011-07-29 2016-09-29 Eleven Biotherapeutics Inc Purified Proteins
BR112015022587A2 (en) 2013-03-13 2017-10-24 Eleven Biotherapeutics Inc chimeric cytokine formulations for ocular delivery
EP3153522A1 (en) 2015-10-09 2017-04-12 Hetero Drugs Limited Process for the purification of erythropoietin and darbepoetin alfa
JP6906497B2 (en) * 2016-03-09 2021-07-21 Ｊｃｒファーマ株式会社 Method for producing mutant human erythropoietin

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856298A (en) * 1989-10-13 1999-01-05 Amgen Inc. Erythropoietin isoforms
US5981716A (en) * 1995-06-07 1999-11-09 Gruppo Lepettit, S.P.A. Process for the purification of proteins
WO2003045996A1 (en) * 2001-11-28 2003-06-05 Sandoz Gmbh Chromatographic purification of recombinant human erythropoietin
EP1428878A1 (en) * 2002-12-13 2004-06-16 Siegfried Ltd. Process for the production and purification of erythropoietin

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856298A (en) * 1989-10-13 1999-01-05 Amgen Inc. Erythropoietin isoforms
US5981716A (en) * 1995-06-07 1999-11-09 Gruppo Lepettit, S.P.A. Process for the purification of proteins
WO2003045996A1 (en) * 2001-11-28 2003-06-05 Sandoz Gmbh Chromatographic purification of recombinant human erythropoietin
EP1428878A1 (en) * 2002-12-13 2004-06-16 Siegfried Ltd. Process for the production and purification of erythropoietin

Also Published As

Publication number Publication date
WO2011063195A2 (en) 2011-05-26

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