WO2011055156A3 - Pharmaceutical compositions comprising an estrogen, a gestagen and various copolymers - Google Patents

Pharmaceutical compositions comprising an estrogen, a gestagen and various copolymers Download PDF

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Publication number
WO2011055156A3
WO2011055156A3 PCT/HU2010/000119 HU2010000119W WO2011055156A3 WO 2011055156 A3 WO2011055156 A3 WO 2011055156A3 HU 2010000119 W HU2010000119 W HU 2010000119W WO 2011055156 A3 WO2011055156 A3 WO 2011055156A3
Authority
WO
WIPO (PCT)
Prior art keywords
gestagen
estrogen
pharmaceutical compositions
various copolymers
copolymers
Prior art date
Application number
PCT/HU2010/000119
Other languages
French (fr)
Other versions
WO2011055156A2 (en
Inventor
Jonathan Mihály NAGY KASZA
László BODAI
Attila Bódis
Ramóna RAJSZKINÉ LABOS
Original Assignee
Richter Gedeon Nyrt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt. filed Critical Richter Gedeon Nyrt.
Publication of WO2011055156A2 publication Critical patent/WO2011055156A2/en
Publication of WO2011055156A3 publication Critical patent/WO2011055156A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Abstract

The present invention relates to ovulation inhibiting pharmaceutical compositions with enhanced stability containing an estrogen and a gestagen type component, and the manufacturing process thereof.
PCT/HU2010/000119 2009-11-06 2010-11-05 Pharmaceutical compositions with enhanced stability WO2011055156A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU0900698A HUP0900698A2 (en) 2009-11-06 2009-11-06 Pharmaceutical compositions of enhanced stability containing drospirenone and ethynyl estradiol and process for their preparation
HUP0900698 2009-11-06

Publications (2)

Publication Number Publication Date
WO2011055156A2 WO2011055156A2 (en) 2011-05-12
WO2011055156A3 true WO2011055156A3 (en) 2011-07-07

Family

ID=89989361

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/HU2010/000119 WO2011055156A2 (en) 2009-11-06 2010-11-05 Pharmaceutical compositions with enhanced stability

Country Status (2)

Country Link
HU (1) HUP0900698A2 (en)
WO (1) WO2011055156A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19728516A1 (en) * 1997-07-04 1999-01-07 Sanol Arznei Schwarz Gmbh TTS for administration of levonorgestrel
WO2009100871A2 (en) * 2008-02-13 2009-08-20 Bayer Schering Pharma Aktiengesellschaft Drug delivery system with stabilising effect
WO2010015713A1 (en) * 2008-08-08 2010-02-11 Bayer Schering Pharma Aktiengesellschaft Progestin-containing drug delivery system

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8001593A (en) 1980-03-18 1981-10-16 Akzo Nv MULTI-PHASIC COMBINATION PREPARATION FOR ORAL ANTI-CONCEPTION.
US4727064A (en) 1984-04-25 1988-02-23 The United States Of America As Represented By The Department Of Health And Human Services Pharmaceutical preparations containing cyclodextrin derivatives
IE67345B1 (en) 1991-03-12 1996-03-20 Akzo Nv Low dose dry pharmaceutical preparations
US5324718A (en) 1992-07-14 1994-06-28 Thorsteinn Loftsson Cyclodextrin/drug complexation
ES2151075T3 (en) 1994-07-04 2000-12-16 Schering Ag LOW DOSE STEROID TABLETS, CONTAINING GALIC ACID ESTERS AS AN ANTIOXIDANT, PROCESS FOR ITS MANUFACTURE AND USE.
CA2159419C (en) 1994-10-17 2006-07-04 Pieter De Haan Solid pharmaceutical composition comprising an excipient capable of binding water

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19728516A1 (en) * 1997-07-04 1999-01-07 Sanol Arznei Schwarz Gmbh TTS for administration of levonorgestrel
WO2009100871A2 (en) * 2008-02-13 2009-08-20 Bayer Schering Pharma Aktiengesellschaft Drug delivery system with stabilising effect
WO2010015713A1 (en) * 2008-08-08 2010-02-11 Bayer Schering Pharma Aktiengesellschaft Progestin-containing drug delivery system

Also Published As

Publication number Publication date
HU0900698D0 (en) 2009-12-28
WO2011055156A2 (en) 2011-05-12
HUP0900698A2 (en) 2011-06-28

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