WO2011039757A3 - Compositions and methods for prognosis of renal cancer - Google Patents

Compositions and methods for prognosis of renal cancer Download PDF

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Publication number
WO2011039757A3
WO2011039757A3 PCT/IL2010/000806 IL2010000806W WO2011039757A3 WO 2011039757 A3 WO2011039757 A3 WO 2011039757A3 IL 2010000806 W IL2010000806 W IL 2010000806W WO 2011039757 A3 WO2011039757 A3 WO 2011039757A3
Authority
WO
WIPO (PCT)
Prior art keywords
prognosis
renal cancer
compositions
methods
nucleic acid
Prior art date
Application number
PCT/IL2010/000806
Other languages
French (fr)
Other versions
WO2011039757A2 (en
Inventor
Moshe Hoshen
Zohar Dotan
Original Assignee
Rosetta Genomics Ltd.
Tel Hashomer Medical Infrastructure And Services Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rosetta Genomics Ltd., Tel Hashomer Medical Infrastructure And Services Ltd. filed Critical Rosetta Genomics Ltd.
Publication of WO2011039757A2 publication Critical patent/WO2011039757A2/en
Publication of WO2011039757A3 publication Critical patent/WO2011039757A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Described herein are compositions and methods for the prognosis of renal cancer patients after surgical operation. Specifically the invention relates to microRNA molecules associated with the prognosis of renal cancer, as well as various nucleic acid molecules relating thereto or derived therefrom.
PCT/IL2010/000806 2009-10-04 2010-10-04 Compositions and methods for prognosis of renal cancer WO2011039757A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24845809P 2009-10-04 2009-10-04
US61/248,458 2009-10-04

Publications (2)

Publication Number Publication Date
WO2011039757A2 WO2011039757A2 (en) 2011-04-07
WO2011039757A3 true WO2011039757A3 (en) 2011-12-29

Family

ID=43826732

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2010/000806 WO2011039757A2 (en) 2009-10-04 2010-10-04 Compositions and methods for prognosis of renal cancer

Country Status (1)

Country Link
WO (1) WO2011039757A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2744910B1 (en) * 2011-08-19 2016-09-14 Hummingbird Diagnostics GmbH Complex sets of mirnas as non-invasive biomarkers for kidney cancer
EP2702998A1 (en) * 2012-08-31 2014-03-05 IMBA-Institut für Molekulare Biotechnologie GmbH Therapeutic and diagnostic miRNA regulator in kidney disease
ES2606790B1 (en) * 2015-09-23 2018-01-17 Fundación Para La Investigación Biomédica Del Hospital 12 De Octubre Prognostic method to identify risk of recurrence in patients with kidney cancer type clear cell renal carcinoma stages I and II and kit

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009036236A1 (en) * 2007-09-14 2009-03-19 The Ohio State University Research Foundation Mirna expression in human peripheral blood microvesicles and uses thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009036236A1 (en) * 2007-09-14 2009-03-19 The Ohio State University Research Foundation Mirna expression in human peripheral blood microvesicles and uses thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GOTTARDO ET AL.: "Micro-RNA profiling in kidney and bladder cancers.", UROL ONCOL, vol. 25, no. 5, 2007, pages 387 - 392, XP022262807, DOI: doi:10.1016/j.urolonc.2007.01.019 *
JUAN ET AL.: "Identification of a microRNA panel for clear-cell kidney cancer.", UROLOGY, vol. 75, no. 4, 29 December 2009 (2009-12-29), pages 835 - 841, XP026990724 *
JUNG ET AL.: "MicroRNA profiling of clear cell renal cell cancer identifies a robust signature to define renal malignancy.", J CELL MOL MED., vol. 13, no. 9B, September 2009 (2009-09-01), pages 3918 - 3928, XP008154297, DOI: doi:10.1111/j.1582-4934.2009.00705.x *

Also Published As

Publication number Publication date
WO2011039757A2 (en) 2011-04-07

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