WO2011037589A1 - Scented and/or flavoured cotton and products therefrom - Google Patents

Scented and/or flavoured cotton and products therefrom Download PDF

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Publication number
WO2011037589A1
WO2011037589A1 PCT/US2009/058610 US2009058610W WO2011037589A1 WO 2011037589 A1 WO2011037589 A1 WO 2011037589A1 US 2009058610 W US2009058610 W US 2009058610W WO 2011037589 A1 WO2011037589 A1 WO 2011037589A1
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WO
WIPO (PCT)
Prior art keywords
cotton
scented
cotton roll
ethyl
methyl
Prior art date
Application number
PCT/US2009/058610
Other languages
French (fr)
Inventor
John Edward Eichelberger
Hyop Seung Rhee
Original Assignee
John Edward Eichelberger
Hyop Seung Rhee
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by John Edward Eichelberger, Hyop Seung Rhee filed Critical John Edward Eichelberger
Priority to PCT/US2009/058610 priority Critical patent/WO2011037589A1/en
Publication of WO2011037589A1 publication Critical patent/WO2011037589A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208—Tissues; Wipes; Patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin

Definitions

  • the invention relates to a scented and/or flavoured cotton, methods of making the cotton, and methods of using the cotton.
  • the cotton may be used in the field of dentistry.
  • Dental procedures can engender anxiety and /or fear in dental patients.
  • Dental procedures include, without limitation, drilling, cavity / carries removal, tooth filling, tooth crowning, root-canals, tooth removal / extraction, implants, brushing, picking, and flossing. These and other dental procedures can result in bleeding and/or the production of saliva in the oral cavity of the dental patient, who can be a human or an animal.
  • cotton products are often employed. The cotton products are usually dry cotton products.
  • Cotton products are frequently used during dental work by dentists to dry a tooth, to absorb fluid (e.g., saliva, blood, water) in the patient's mouth, to prevent an oral surface from being contacted by water, saliva, blood or other fluid, or to shield a surface from coming into contact with, for example, a dental adhesive, a dental sealant, and /or a dental cement.
  • Cotton rolls are typically placed between the tongue and teeth and/or gum, and between the cheek and teeth and/or gum to allow a surface to remain isolated and dry.
  • dental patients are oftentimes asked to bite down on cotton rolls after a crown is installed to keep it in the proper position. These dental cotton rolls do not have any scents and/or flavours. Representative dry dental cotton rolls are shown in Fig. 1.
  • the dental procedures can be stressful, unpleasant, anxiety producing, fear engendering, and/or painful, it is desirable to find ways to make dental procedures more enjoyable. Decreasing the stress, unpleasantness, anxiety, fear and/or pain associated with a dental visit, a desirable goal in and of itself, can also facilitate better long term oral health by, for example, making patients more likely to visit a dentist on a regular basis, and, by making it more likely that a patient will undergo, when needed, dental procedure(s).
  • Flavour is the sensory impression of a substance, such as a cotton product, and is determined mainly by the chemical senses of taste and smell.
  • a flavourant gives a substance flavour; smell is a main determinant of a substance's flavour.
  • smell and flavour are intimately intertwined; and flavour of a substance easily altered by changing its smell (e.g., by changing its scent).
  • the taste of a substance is believed to be limited to the basic tastes of, for example, sweet, sour, bitter, salty, and savory, and combinations thereof, the number of smells that can be imparted to a substance is significantly greater.
  • a substance's flavour therefore, can be altered by changing its smell / scent.
  • the present inventors determined that one way to decrease the stress, unpleasantness, anxiety, fear and/or pain associated with a dental visit can be, for example, to impart a scent and/or flavour to a cotton or cotton product that can be used, for example, in a dental procedure, thus giving rise to the inventive embodiments described herein.
  • Figure 1 shows standard dry dental cotton rolls.
  • Figure 2 shows a right circular cylinder, a shape which the inventive cotton may adopt.
  • Figure 3 shows a beam, a shape which the inventive cotton may adopt.
  • Figure 4 shows a unscented / unflavoured cotton roll (top) and a scented / flavoured, sweetened and colored cotton roll (bottom).
  • the inventive cotton may be, for example, a dental cotton product that can be dry or can be wet (e.g., can contain a liquid absorbed therein).
  • the cotton employed in the inventive embodiments is preferably cotton that has been removed from a cotton boll (e.g., the rounded seed pod of the cotton plant), and further preferably cleaned, and further, preferably ginned (e.g., the cotton fibers are separated from, for example, the cotton seeds and/or stems).
  • the cotton employed in the inventive embodiments can be cotton where cotton fibers have been carded (e.g., aligned) and spun for form for example, threads.
  • the cotton threads can be woven into a fabric that can be employed in the inventive embodiments, or spun into a yarn that can be employed in the inventive embodiments.
  • the type of cotton is not limited and can be, for example, American, Brazilian, Peruvian, Egyptian, and/or Asiatic cotton.
  • the cotton can be, for example, a natural cotton and/or a genetically modified cotton.
  • the cotton can be, for example, a shiny cotton.
  • the cotton can be, for example, in the form of a fiber and/or a yarn.
  • the cotton fibers can range in width, for example, from 1 to 100 micrometers, preferably, 12-20 micrometers, including all values, ranges, and subranges therebetween.
  • the cotton fibers, without being limiting can range in length, for example, from 1 cm to 20 cm, preferably 1 cm to 6 cm, more preferably 2.2 cm to 3.3 cm in length, including all values, ranges, and subranges therebetween.
  • the luster of the cotton fibers can be for example, low, medium and/or high luster, and is preferably high luster.
  • the tenacity (strength) of the cotton fibers can be, without being limiting, when wet, for example, 1.0 - 10.0 g/d, preferably 3.0-5.0 g/d, including all values, ranges, and subranges therebetween.
  • the tenacity (strength) of the cotton fibers can be, without being limiting, when dry, for example, 1 .0 - 20.0 g/d, preferably 3.3-6.0 g/d, including all values, ranges and subranges therebetween.
  • the mositure absorption of the cotton fibers can be, without being limiting, for example, can range from 1 % to 30% including all values, ranges, and subranges therebetween.
  • the cotton or cotton product is not limited in shape or form, examples of the cotton product include cotton balls, cotton strips, cotton pellets, cotton beams, cotton cubes, and cotton rolls; a cotton roll is a preferred cotton product.
  • a further version of the cotton product includes the cotton tip on an applicator (e.g., a small wad of cotton wrapped around one or both ends of a rod, the rod comprising, for example, wood, plastic, rolled paper, a metal, and/or combinations of these materials).
  • Additional variations of the cotton product include a cotton gauze (e.g., a thin, translucent fabric with a loose open weave), a cotton bandage, a cotton bib, and a cotton face mask.
  • the cotton component is a non-woven cotton.
  • the cotton product is not in the form of a filament (e.g., thread). In another embodiment, the cotton product is in the form of a filament.
  • a face mask includes a mask component and optionally an attachment component (for example, a piece of elastic and/or or an adhesive strip), and that a cotton bib includes a bib component and optionally an attachment component (such as a plastic or metal or elastic strip or wire with fasteners, such as clamps or snaps or buttons, at each end of the strip or wire, that attach to the bib).
  • a face mask includes variations where the mask component of the face mask covers both the nose and the mouth, covers the nose, covers a potion of the nose, or covers all or part of the area between the nose and the mouth.
  • the mask is employed by placing the mask on the face of a person or animal, preferably a person or animal in need thereof, such that it covers the nose, the mouth, a portion of the nose, or all or part of the area between the nose and mouth.
  • the mask may be employed, for example, on a patient, preferably a patient in need thereof, a dentist, preferably a dentist in need thereof, or other dental professional such as a dental hygienist, preferably a dental hygienist in need thereof.
  • the mask may, for example, when employed, mask the breath of the person or animal for to which the mask is employed, and may, for example, mask bad breath or halatosis.
  • a roll is cylindrically shaped.
  • the cylinder can have, for example, without being limited, a cross section that is an ellipse, parabola, or hyperbola, or circle.
  • the roll is a right circular cylinder, with its ends being two circular surfaces.
  • the right circular cylinder has a height, h, and a diameter, d, as shown in Fig. 2.
  • the height, h can range from 1 nm to 50 cm, including all ranges, subranges, and values therebetween.
  • the height, h can be, for example, 1 nm, 10, nm, 100 nm, 200 nm, 300 nm, 400 nm, 500 nm, 600 nm, 700 nm, 800 nm, 900 nm, 1 ⁇ , 2 ⁇ , 3 ⁇ , 4 ⁇ , 5 ⁇ , 6 ⁇ , 7 ⁇ , 8 ⁇ , 9 ⁇ , 10 ⁇ , 50 ⁇ , 100 ⁇ , 200 ⁇ , 300 ⁇ , 400 ⁇ , 500 ⁇ , 600 ⁇ , 700 ⁇ , 800 ⁇ , 900 ⁇ , 1 mm, 2 mm, 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 8 mm, 9 mm, 10, mm, 50 mm, 100 mm, 200 mm, 300 mm, 400 mm, 500 mm, 600 mm, 500 mm, 50
  • the diameter, d for example, without being limiting can range from 1 nm to 50 cm, including all ranges, subranges, and values therebetween.
  • the diameter, d can be, for example, 1 nm, 10, nm, 100 nm, 200 nm, 300 nm, 400 nm, 500 nm, 600 nm, 700 nm, 800 nm, 900 nm, 1 ⁇ , 2 ⁇ , 3 ⁇ , 4 ⁇ , 5 ⁇ , 6 ⁇ , 7 ⁇ , 8 ⁇ , 9 ⁇ , 10 ⁇ , 50 ⁇ , 100 ⁇ , 200 ⁇ , 300 ⁇ , 400 ⁇ , 500 ⁇ , 600 ⁇ , 700 ⁇ , 800 ⁇ , 900 ⁇ , 1 mm, 2 mm, 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 8 mm, 9 mm, 10, mm, 50 mm, 100 mm, 200 mm, 300 mm, 400 mm, 500 mm, 600 mm
  • the cotton product is in the shape of a beam.
  • a beam has a length, 1, height, h, and width, w, as shown in Fig. 3.
  • the height, h for example, without being limiting can range from 1 nm to 50 cm, including all ranges, subranges, and values therebetween.
  • the height, h can be, for example, 1 nm, 10, nm, 100 nm, 200 nm, 300 nm, 400 nm, 500 nm, 600 nm, 700 nm, 800 nm, 900 nm, 1 ⁇ , 2 ⁇ , 3 ⁇ , 4 ⁇ , 5 ⁇ , 6 ⁇ , 7 ⁇ , 8 ⁇ , 9 ⁇ , 10 ⁇ , 50 ⁇ , 100 ⁇ , 200 ⁇ , 300 ⁇ , 400 ⁇ , 500 ⁇ , 600 ⁇ , 700 ⁇ , 800 ⁇ , 900 ⁇ , 1 mm, 2 mm, 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 8 mm, 9 mm, 10, mm, 50 mm, 100 mm, 200 mm, 300 mm, 400 mm, 500 mm, 600 mm
  • the length, 1, for example, without being limiting can range from 1 nm to 50 cm, including all ranges, subranges, and values therebetween.
  • the length, 1, without being limiting can be, for example, 1 nm, 10, nm, 100 nm, 200 nm, 300 nm, 400 nm, 500 nm, 600 nm, 700 nm, 800 nm, 900 nm, 1 ⁇ , 2 ⁇ , 3 ⁇ , 4 ⁇ , 5 ⁇ , 6 ⁇ , 7 ⁇ , 8 ⁇ , 9 ⁇ , 10 ⁇ , 50 ⁇ , 100 ⁇ , 200 ⁇ , 300 ⁇ m, 400 ⁇ , 500 ⁇ , 600 ⁇ , 700 ⁇ m, 800 ⁇ , 900 ⁇ , 1 mm, 2 mm, 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 8 mm, 9 mm, 10, mm, 50 mm, 100 mm, 200 mm, 300 mm, 400 mm, 500 mm
  • the width, w for example, without being limiting can range from 1 nm to 50 cm, including all ranges, subranges, and values therebetween.
  • the width, w can be, for example, 1 nm, 10, nm, 100 nm, 200 nm, 300 nm, 400 nm, 500 nm, 600 nm, 700 nm, 800 nm, 900 nm, 1 ⁇ , 2 ⁇ , 3 ⁇ , 4 ⁇ , 5 ⁇ , 6 ⁇ , 7 ⁇ , 8 ⁇ , 9 ⁇ , 10 ⁇ , 50 ⁇ , 100 ⁇ , 200 ⁇ , 300 ⁇ , 400 ⁇ , 500 ⁇ , 600 ⁇ , 700 ⁇ , 800 ⁇ , 900 ⁇ , 1 mm, 2 mm, 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 8 mm, 9 mm, 10, mm, 50 mm, 100 mm, 200 mm, 300 mm, 400 mm, 500 mm, 600 mm
  • the cotton or cotton product can have a weight, without being limiting, ranging from, for example, 0.1 ng to lOOg, including all ranges, values and subranges therebetween.
  • the cotton product can, without being limiting, weigh, for example 1 ng, 10 ng, 100 ng, 500 ng, 1 ⁇ 3 ⁇ 4 , 10 ⁇ 3 ⁇ 4 , 100 ⁇ 8 , 500 ⁇ , 1 mg, 10 mg, 100 mg, 500 mg, 1 g, 5 g, 10 g, 25 g, or 50 g.
  • the cotton product in addition to comprising cotton, may comprise other materials, either alone or in combination, including, but not limited to, a rubber, a silicone, a silk, a polysaccharide in addition to the polysaccharide(s) that naturally comprise cotton, a polyester, a polyamide, a polyurethane, a polycarbonate, a polystyrene, a thermoplastic polymer, a nucleic acid polymer, such as DNA or RNA, polyethylene, polypropylene, polybutylene, a copolymer, which may, for example, be a block copolymer or a random copolymer, a cellulose nitrate, a cellulose acetate, a polyvinyl chloride, and combinations of these materials.
  • a rubber a silicone
  • a silk a polysaccharide in addition to the polysaccharide(s) that naturally comprise cotton
  • a polyester a polyamide, a polyurethane, a polycarbonate, a
  • any of these materials can be comprised, for example, in the form of threads.
  • the cotton product does not comprise any of the materials listed in this paragraph.
  • the cotton product does not comprise any polymer other than the polymer(s) naturally found in cotton.
  • flavour and / or scent the cotton or cotton product comprises, when comprising a flavour and/or scent, is not limited to any particular flavour / scent or combinations of flavours / scents.
  • flavours and/or scents include, but are not limited to, lemon, lime, coffee, peach, jasmine, mint, peppermint, honey, root beer, wintergreen, orange, fruity, rum, coffee, chocolate, cocoa, butter, cream, cherry, apricot, grape, pineapple, pear, strawberry, jasmine, cinnamon, vanilla, almond, apple, marshmallow, banana, strawberry, bubble gum, raspberry, pepper, tea, caramel and combinations of these flavours / scents.
  • flavours and / or scents that the cotton or cotton product can comprise:
  • the cotton product can be pineapple scented and/or flavoured by allyl hexanoate, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be pear and/or strawberry and/or jasmine scented and/or flavoured by benzyl acetate, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be banana and/or pineapple and/or strawberry scented and/or flavoured by ethyl butyrate, alone or in
  • the cotton or cotton product can be strawberry scented and/ or flavoured by ethyl hexanoate, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be pineapple scented by butyl butyrate, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be cinnamon scented and/or flavoured by ethyl cinnamate, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be lemon and/or rum and/or raspberry and/or strawberry scented and/or flavoured by ethyl formate, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be apricot and/or cherry and/or raspberry and/or grape scented and/or flavoured by ethyl heptanoate, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be apple scented and/or flavoured by ethyl isovalerate, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be butter and/or cream scented and/or flavoured by ethyl lactate, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be grape scented and/or flavoured by ethyl nonanoate, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be apple scented and/or flavoured by ethyl pentanoate, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be cherry scented and/or flavoured by geranyl butyrate, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be apple scented and/or flavoured by geranyl pentanoate, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be chocolate and/or cocoa and/or coffee scented and/or flavoured by 2,5-dimethylpyrazine, alone or in
  • the cotton or cotton product can be cherry and/or strawberry and/or raspberry scented and/or flavoured by isobutyl acetate, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be honey scented and/or flavoured by methyl phenyl acetate, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be root beer and/or wintergreen scented and/or flavoured by methyl salicylate, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be orange scented and/or flavoured by nonyl caprylate, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be scented by vanillin (e.g.,4-hydroxy-3- methoxy benzaldehyde), alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be scented and/or flavored by benzaldehyde (e.g., almond scented and/or flavored), alone or in combination with other scents and/or flavours.
  • benzaldehyde e.g., almond scented and/or flavored
  • the cotton or cotton product can be popcorn scented and/or flavored by employing methyl-2-pyridyl ketone, alone or in combination with other scents and/or flavors.
  • the cotton or cotton product can be apple scented and /or flavoured by employing ethyl-2-methyl butyrate, alone or in combination with other scents and / or flavors.
  • the cotton or cotton product can be marshmallow scented and/or flavoured by employing ethyl-3-hydroxy butanoate, alone or in combination with other scents and / or flavors.
  • the cotton or cotton product can be banana and/or pear scented and /or flavoured by employing banana oil (e.g., isoamyl acetate), alone or in combination with other scents and /or flavours.
  • banana oil e.g., isoamyl acetate
  • the cotton or cotton product can be strawberry scented and / or flavoured by employing strawberry oil (e.g., ethyl methylphenylglycidate), alone or in combination with other scents and / or flavours.
  • the cotton or cotton product can be bubble gum scented and / or flavoured by employing prenyl acetate (e.g., 3-methyl-2-butenyl acetate), alone or in combination with other scents and / or flavours.
  • scents and/or flavours that can be used alone or in combination with any other scent and /or flavour include, but are not limited to, for example, isobutyl formate, isopropyl acetate, linalyl acetate, linalyl butyrate, linalyl formate, methyl acetate, methyl anthranilate, methyl benzoate methyl benzyl acetate, methyl butyrate, methyl cinnamate, methyl pentanoate, octyl acetate, octyl butyrate, amyl acetate, amyl butyrate, pentyl hexanoate, pentyl pentanoate, propyl ethanoate, propyl isobutyrate, and terpenyl butyrate.
  • the amount of each of these scents and/or flavours, individually, comprised in the cotton or cotton product is not limited and can range, for example, from 0.1 ng to 10 g, including all values, ranges, and subranges therebetween.
  • the amount can be 10 ng, 25 ng, 50 ng, 75 ng, 100 ng, 200 ng, 300 ng, 400 ng, 500 ng, 600 ng, 700 ng, 800 ng, 900 ng, 1 ⁇ g, 2 ⁇ g, 3 ⁇ ⁇ , 4 ⁇ ⁇ , 5 ⁇ ⁇ , 6 ⁇ ⁇ , 7 ⁇ 8 , 8 ⁇ ⁇ , 9 ⁇ ⁇ , 10 ⁇ ⁇ , 25 ⁇ ⁇ , 50 ⁇ ⁇ , 75 ⁇ ⁇ , 100 ⁇ ⁇ , 200 ⁇ ⁇ , 300 ⁇ ⁇ , 400 ⁇ ⁇ , 500 ⁇ ⁇ , 600 ⁇ g, 700 ⁇ g, 800 ⁇ g, 900 ⁇ g, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg, 80 mg, 90 mg,
  • the cotton or cotton product can contain a taste ingredient, alone or in combination, that imparts a taste of at least one of sweet, sour, bitter, salty, and and/or savory (e.g., a sweetener, a souring ingredient, a salt, a bittering ingredient, and /or a savory ingredient).
  • the cotton or cotton product does not comprise an added taste ingredient that imparts a taste of at least one of sweet, sour, bitter, salty, and and/or savory.
  • the cotton or cotton product can comprise one or more sweeteners, either alone or in combination.
  • sweeteners include aspartame, saccharine, acesulfame k (e.g, potassium), sucralose, erythritol, hydrogenated starch hydrolysates, isomalt, lactitol, maltitol, mannitol, sorbitol, xylitol, and stevia.
  • the one or more sweeteners can each, be employed, individually or in combination of two or more.
  • the amount of each sweetener comprised in the cotton or cotton product is not limited and can range, for example, from 0. 1 ng to 1 g, including all values, ranges, and subranges therebetween.
  • the amount can be 1 ng, 10 ng, 25 ng, 50 ng, 75 ng, 100 ng, 200 ng, 300 ng, 400 ng, 500 ng, 600 ng, 700 ng, 800 ng, 900 ng, 1 ⁇ g, 2 ⁇ g, 3 ⁇ g, 4 ⁇ g, 5 ⁇ g, 6 g, 7 ⁇ g, 8 ⁇ g, 9 ⁇ g, 10 ⁇ g, 25 ⁇ , 50 75 ⁇ , 100 ⁇ g, 200 ⁇ ⁇ , 300 ⁇ ⁇ , 400 ⁇ 3 ⁇ 4 , 500 ⁇ ⁇ , 600 ⁇ ⁇ , 700 ⁇ ⁇ , 800 ⁇ ⁇ , 900 ⁇ ⁇ , 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 nig, 7 mg, 8 mg, 9 mg, 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg, 80 mg, 90 mg, 100 mg, 200 mg, 300 mg, 400 mg, 500 mg, 60
  • the cotton or cotton product can comprise one or more salts.
  • Salts include, for example, magnesium chloride, potassium chloride, calcium chloride, monosodium glutamate, sodium fluoride, potassium fluoride, and/or sodium chloride.
  • the salts can be cationic metal salts of an organic anion and /or an inorganic anion.
  • the amount of each salt comprised in the cotton or cotton product is not limited and can range, for example, from 0.1 ng to 1 g, including all values, ranges, and subranges therebetween.
  • the amount can be 1 ng, 10 ng, 25 ng, 50 ng, 75 ng, 100 ng, 200 ng, 300 ng, 400 ng, 500 ng, 600 ng, 700 ng, 800 ng, 900 ng, 1 ⁇ g, 2 ⁇ g, ⁇ g, 4 ⁇ ⁇ , 5 ⁇ ⁇ , 6 ⁇ ⁇ , 7 ⁇ g, 8 ⁇ & 9 ⁇ 3 ⁇ 4 , 10 ⁇ g, 25 ⁇ g, 50 ⁇ ⁇ , 75 ⁇ ⁇ , 100 ⁇ g, 200 ⁇ ⁇ , 300 ⁇ g, 400 ⁇ g, 500 ⁇ ⁇ , 600 ⁇ g, 700 ⁇ ⁇ , 800 ⁇ 3 ⁇ 4 , 900 ⁇ g, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg, 80 mg, 90 mg, 100 mg, 200 mg, 30 mg
  • the cotton or cotton product can comprise one or more souring ingredients.
  • Souring ingredients for example, such as citric acid, a salt thereof (such as sodium, potassium, calcium or magnesium citrate), an ester thereof (such as triethyl citrate), vitamin c (e.g., ascorbic acid, L-ascorbic acid), and /or a salt thereof (such as sodium, potassium, calcium or magnesium ascorbate), and combinations thereof.
  • the amount of each souring ingredient comprised in the cotton or cotton product is not limited and can range, for example, from 0.1 ng to 1 g, including all values, ranges, and subranges therebetween.
  • the amount can be 1 ng, 10 ng, 25 ng, 50 ng, 75 ng, 100 ng, 200 ng, 300 ng, 400 ng, 500 ng, 600 ng, 700 ng, 800 ng, 900 ng, 1 ⁇ g, 2 ⁇ ⁇ , 3 ⁇ g, 4 ⁇ g, 5 ⁇ & 6 ⁇ ⁇ , 7 ⁇ ⁇ , 8 ⁇ ⁇ , 9 ⁇ g, 10 ⁇ ⁇ , 25 ⁇ 3 ⁇ 4 , 50 ⁇ ⁇ , 75 ⁇ 8 , 100 ⁇ & , 200 ⁇ ⁇ , 300 ⁇ 8 , 400 ⁇ ⁇ , 500 ⁇ ⁇ , 600 ⁇ g, 700 ⁇ ⁇ , 800 ⁇ ⁇ , 900 ⁇ g, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg, 80 mg, 90 mg, 50
  • the cotton or cotton product can comprise one or more bittering ingredients, such as quinine, or a salt thereof, such as an HC1 salt, or any pharmacologically acceptable salt of quinine or of the bittering agent.
  • bittering ingredients such as quinine, or a salt thereof, such as an HC1 salt, or any pharmacologically acceptable salt of quinine or of the bittering agent.
  • the amount of each bittering agent comprised in the cotton or cotton product is not limited and can range, for example, from 0.1 ng to 1 g, including all values, ranges, and subranges therebetween.
  • the amount can be 1 ng, 10 ng, 25 ng, 50 ng, 75 ng, 100 ng, 200 ng, 300 ng, 400 ng, 500 ng, 600 ng, 700 ng, 800 ng, 900 ng, 1 ⁇ ⁇ , 2 ⁇ ⁇ , 3 ⁇ , 4 ⁇ , 5 ⁇ ⁇ , 6 ⁇ ⁇ , 7 ⁇ ⁇ , 8 ⁇ g, 9 ⁇ g, 10 ⁇ g, 25 ⁇ g, 50 ⁇ ⁇ , 75 ⁇ ⁇ , 100 ⁇ ⁇ , 200 ⁇ ⁇ , 300 ⁇ g, 400 ⁇ ⁇ , 500 ⁇ ⁇ , 600 ⁇ ⁇ , 700 ⁇ ⁇ , 800 ⁇ ⁇ , 900 ⁇ g, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg, 80 mg, 90 mg, 50
  • the cotton or cotton product can comprise at least one of an antiseptic, an antibiotic, an antifungal, a cleaning agent, a local anesthetic, a preservative, a surfactant, such as a poloxamer, and /or combinations thereof.
  • the amount of each antiseptic, antibiotic, antifungal, cleaning agent, and local anesthetic that can be comprised in the cotton or cotton product is not limited and can be present in an amount ranging, for example from from 0.1 ng to 10 g, including all values, ranges, and subranges therebetween.
  • the amount can be 1 ng, 10 ng, 25 ng, 50 ng, 75 ng, 100 ng, 200 ng, 300 ng, 400 ng, 500 ng, 600 ng, 700 ng, 800 ng, 900 ng, 1 ⁇ g, 2 ⁇ g, 3 ⁇ ⁇ , 4 ⁇ g, 5 ⁇ g, 6 ⁇ & 1 ⁇ ⁇ , 8 ⁇ g, 9 ⁇ ⁇ , 10 ⁇ g, 25 ⁇ 3 ⁇ 4 , 50 ⁇ 3 ⁇ 4 , 75 ⁇ 3 ⁇ 4 , 100 ⁇ g, 200 ⁇ ⁇ , 300 ⁇ g, 400 ⁇ & 500 ⁇ ⁇ , 600 ⁇ ⁇ , 700 ⁇ ⁇ , 800 ⁇ ⁇ , 900 ⁇ g, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg, 80 mg, 90 mg, 100 mg,
  • the cotton or cotton product does not comprise any of an antiseptic, an antibiotic, an antifungal, a cleaning agent, a local anesthetic, a surfactant, a preservative, and /or combinations thereof.
  • these substances include menthol, thymol, methyl silicylate, eucalyptol, and cetylpyridinium chloride.
  • the cotton or cotton product can comprise a fluoride comprising compound.
  • the fluoride comprising compound include, for example, sodium fluoride, hexafluorosilicic acid, (H 2 SiF 6 ), sodium hexafluorosilicate (Na 2 SiF 6 ), and combinations thereof.
  • Each fluoride comprising compound can be, for example,
  • the amount is not limited and can be in an amount ranging, for example, from from 0.1 ng to 1 g, including all values, ranges, and subranges therebetween.
  • the amount can be 1 ng, 10 ng, 25 ng, 50 ng, 75 ng, 100 ng, 200 ng, 300 ng, 400 ng, 500 ng, 600 ng, 700 ng, 800 ng, 900 ng, 1 ⁇ g, 2 ⁇ ⁇ , 3 ⁇ g, 4 ⁇ g, 5 ⁇ ⁇ , 6 ⁇ g, 7 ⁇ g, 8 ⁇ g, 9 ⁇ & 10 ⁇ g, 25 ⁇ g, 50 ⁇ ⁇ , 75 ⁇ ⁇ , 100 ⁇ ⁇ , 200 ⁇ g, 300 ⁇ g, 400 ⁇ g, 500 ⁇ g, 600 ⁇ g, 700 ⁇ g, 800 ⁇ g, 900 ⁇ g, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg.
  • the cotton or cotton product comprises menthol, thymol, methyl silicylate, and eucalyptol.
  • a solution comprising alcohol (such as ethanol) in an amount of 26.1 % by weight, based on the weight of the solution, eucalyptol in an amount of 0.092% by weight, based on the weight of the solution, menthol in an amount of 0.042% by weight, based on the weight of the solution, methyl salicylate, in an amount of 0.060% by weight, based on the weight of the solution, and thymol in an amount of 0.064%o by weight, based on the weight of the solution, with the remainder of the solution being water and /or other ingredients, is employed as a spraying or dipping solution for the cotton or cotton product, which, after spraying or dipping, can optionally be dried to reduce and /or remove the ethanol and / or water.
  • alcohol such as ethanol
  • antibiotics examples include, but are not limited to, Amikacin, Gentamicin, Kanamycin Neomycin, Netilmicin, Streptomycin, Tobramycin, Paromomycin, Ansamycins, Geldanamycin, Herbimycin, Carbacephem, Loracarbef, Carbapenems, Ertapenem,
  • Cefprozil Cefuroxime, Cephalosporins, Cefixime, Cefdinir, Cefditoren, Cefoperazone, Cefotaxime, Cefpodoxime, Ceftazidime, Ceftibuten, Ceftizoxime, Ceftriaxone,
  • Ceftobiprole Glycopeptides, Teicoplanin, Vancomycin, Macrolides, Azithromycin,
  • Clarithromycin Dirithromycin, Erythromycin, Roxithromycin, Troleandomycin
  • Polypeptides Bacitracin, Colistin, Polymyxin B, Quinolones, Ciprofloxacin, Enoxacin, Gatifloxacin, Levofloxacin, Lomefloxacin, Moxifloxacin, Norfloxacin, Ofloxacin,
  • Prontosil Sulfacetamide, Sulfamethizole, Sulfanilimide, Sulfasalazine, Sulfisoxazole, Trimethoprim, Trimethoprim-Sulfamethoxazole (Co-trimoxazole), Tetracyclines
  • Arsphenamine Chloramphenicol, Clindamycin, Lincomycin, Ethambutol, Fosfomycin, Fusidic acid, Furazolidone, Isoniazid, Linezolid, Metronidazole, Mupirocin, Nitrofurantoin, Platensimycin, Pyrazinamide, Quinupristin Dalfopristin, Rifampicin, Thiamphenicol, Tinidazole, and combinations thereof.
  • antifungals include, but are not limited to, Itraconazole, Ketoconazole, Fluconazole, Voriconazole, Nystatin, Flucytosine, Amphotericin B, Griseofulvin,
  • Examples of local anesthetics include, but are not limited to,
  • Lidocaine Articaine, Bupivacaine, Carticaine, Cinchocaine/Dibucaine, Etidocaine,
  • Levobupivacaine Lidocaine/Lignocaine, Mepivacaine, Piperocaine, Prilocaine, Ropivacaine, Trimecaine, Lidocaine/prilocaine, Saxitoxin, Tetrodotoxin and combinations thereof.
  • the cotton or cotton product can be colored.
  • colors include, but are not limited to, red, orange, yellow, green, blue, indigo, violet, white, brown, black, and combinations thereof.
  • colorings that can be used to color the cotton orcotton product include, but are not limited to, FD&C Blue No. 1 - Brilliant Blue FCF, El 33 (Blue shade), FD&C Blue No. 2 - Indigotine, El 32 (Dark Blue shade), FD&C Green No. 3 - Fast Green FCF, E l 43 (Bluish green shade), FD&C Red No. 40 - Allura Red AC, El 29 (Red shade), FD&C Red No. 3 - Erythrosine, E127 (Pink shade), FD&C Yellow No. 5 - Tartrazine, E l 02 (Yellow shade), FD&C Yellow No. 6 - Sunset Yellow FCF, El 10 (Orange shade), and combinations thereof.
  • any flavour / scent, color, taste ingredient, antifungal, antiseptic, local anesthetic, and/or cleaning agent in short, any ingredient comprised in the cotton or cotton product, may, as appropriate, be comprised as a neutral molecule, such as an ester, a zwitterion, such as an amino acid, either D, L, or racemic, an acid, a base, a free base, or a salt, such as an organic or an inorganic salt, as appropriate.
  • any flavour / scent, color, taste ingredient, antifungal, antiseptic, local anesthetic, and/or cleaning agent in short, any ingredient comprised in the cotton or cotton product, may, as appropriate, be chiral non-racemic, racemic, a diastereomer, or a geometric isomer.
  • Any ingredient including but not limited to flavour(s) and/or scent(s), coloring agent(s), taste ingredient(s), antibiotic(s), and antifungal(s), individually, is not limited in the amount comprised in the cotton or cotton product, and can be comprised, on wt% basis relative to the total weight of the cotton or cotton product, in an amount ranging ranging, for example, from 0.00001 wt% to 99.99999 wt%, including all values, ranges, and subranges therebetween.
  • the ingredient can be comprised in the cotton product in 0.0001 wt%, 0.001 wt%, 0.01 wt%, 0.1 wt%, 1.0 wt%, 10 wt%, 20 wt%, 30 wt%, 40 wt%, 50 wt%, 60 wt%, 70 wt%, 80 wt%, or 90 wt%.
  • Any ingredient including but not limited to flavour(s) and/or scent(s), coloring agent(s), taste ingredient(s), antibiotic(s), and antifungal(s), individually, is not limited in the amount comprised in the cotton or cotton product, and may be comprised in the cotton or cotton product, for example, in an amount ranging from 0.1 ng to 100 g, including all values, ranges, and subranges therebetween.
  • any ingredient can be comprised in an amount of 10 ng, 25 ng, 50 ng, 75 ng, 100 ng, 200 ng, 300 ng, 400 ng, 500 ng, 600 ng, 700 ng, 800 ng, 900 ng, 1 ⁇ g, 2 ⁇ g, 3 ⁇ , 4 ⁇ g, 5 ⁇ g, 6 ⁇ g, ⁇ ⁇ g, 8 ⁇ g, 9 Mg, 10 ⁇ g, 25 ⁇ g, 50 ⁇ g, 75 ⁇ g, 100 ⁇ g, 200 ⁇ ⁇ , 300 ⁇ ⁇ , 400 ⁇ g, 500 ⁇ ⁇ , 600 ⁇ g, 700 ⁇ ⁇ , 800 ⁇ & 900 ⁇ g, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg, 80 mg, 90 mg, 100 mg, 200 mg, 300 mg, 400 mg, 500 mg, 600 mg, 300 mg
  • flavour and /or scent and/or color and/or sweetener and/or taste ingredient and/or antiseptic and/or antifungal and/or antibacterial and/or local anesthetic and/or cleaning agent can be applied to a cotton or shaped cotton (e.g., applied to a cotton roll) to form the cotton product, or can be applied to a cotton material before the cotton material is shaped / formed into the cotton product (e.g., applied to a cotton, or a cotton fabric or cotton weave, before the cotton, fabric, or cotton weave is shaped into the cotton product such as a cotton roll).
  • the method of applying the flavour and /or scent and/or color and/or sweetener and/or antiseptic and/or antifungal and/or antibacterial is not limited.
  • the flavour and /or scent and/or color and/or sweetener and/or antiseptic and/or antifungal and/or antibacterial can be directly applied as a solid, for example as a powder, or an oil.
  • the flavour and /or scent and/or color and/or sweetener and/or antiseptic and/or antifungal and/or antibacterial can be applied dissolved or dispersed in a solution.
  • the solution can be a single solvent or a mixture of solvents, for example, a water solution, an ethanol solution, a supercritical carbon dioxide solution, or a mixture of these.
  • Each ingredient in the solution can be contained, without being limiting, for example in a concentration ranging from 0.1 nanomolar to 10 molar, including all ranges, subranges, and values therebetween.
  • each ingredient can be contained in the solution in a concentration of 1 nanomolar, 10 nanomolar, 100 nanomolar, 500 nanomolar, 1 ⁇ ⁇ , 10 ⁇ -nolar, 100 ⁇ -nolar, 500 ⁇ , 1 millmolar, 10 millimolar, 50 millimolar, 100 millimolar, 500 millimolar, 1 molar, 5 molar, and 10 molar.
  • the solution can be applied, for example, by spraying or by dipping.
  • the ingredients can be present in the same solution, or can be applied using separate solutions, at the same time or sequentially.
  • the cotton or cotton product, after application of the solution can be used wet or dried before use.
  • Drying temperatures are not limited and drying can be conducted, for example, at a temperature ranging from -78 °C to 200 °C, including all values, ranges, and subranges therebetween.
  • drying can be conducted at - 10 °C, 0 °C, 10 °C, 20 °C, 30 U C, 40 °C, 50 °C, 60 °C, 70 "C, 80 °C, or 90 °C.
  • the drying without being limited, can be conducted under reduced pressure and/or vacuum, for example, from 0.99 atm to 0.000001 atm, including all values, ranges, and subranges therebetween.
  • the cotton product can be sterile or can be unsterilized.
  • Sterilizing the cotton product can be effected, for example, by heat, including dry heat, high pressure, and/or irradiation.
  • the materials used in and/or to make the cotton or cotton product, including the cotton can be sterilized prior to forming the cotton or cotton product, the formation of which can be done in a sterile environment, such as a clean room.
  • the flavour and /or scent and/or color and/or sweetener and/or antiseptic and/or antifungal and/or antibacterial and/or taste ingredient can be applied, or any ingredient, for example, can be applied to at least a portion of at least one surface of the cotton or cotton product, can be applied to a surface of the cotton or cotton product, can be applied to all surfaces of the cotton or cotton product, can be applied to a portion of the interior of the cotton or cotton product, can be applied to the interior of the cotton or cotton product, can be applied to the surface and the interior of the cotton or cotton product, or combinations of these.
  • the flavour and /or scent and/or color and/or sweetener and/or antiseptic and/or antifungal and/or antibacterial and/or taste ingredient can be further applied with other materials such a lubricant, a glidant, a binder, an emulsifier, a filler, an excipient, and combinations of these materials.
  • the inventive embodiments include a method of placing the scented and/or flavoured cotton or cotton product into the oral cavity of a human or animal, preferably a human or animal in need thereof, comprising introducing the scented and/or flavoured cotton or cotton product into the oral cavity of the human or animal.
  • the inventive embodiments include a method of inducing experiencing of a scent and/or flavour and/or taste in a human or animal, preferably a human or animal in need thereof, comprising, placing the scented and/or flavoured cotton or cotton product into the oral cavity of the human or animal.
  • the inventive embodiments include a method of inducing experiencing of a scent and/or flavour and/or taste in a human or animal, collectively animals including humans are subjects, preferably a human or animal or subject in need thereof, comprising, placing the scented and/or flavoured cotton or cotton product over the space between the mouth and nose, of the human or animal.
  • the inventive embodiments include a method of inducing recognition of a scent and/or flavour and/or taste in a human or animal, preferably a human or animal in need thereof, comprising, placing the scented and/or flavoured cotton or cotton product over the nose or of the human or animal, preferably a human or animal in need thereof.
  • the inventive embodiments include a method of absorbing a fluid, preferably blood, saliva, or water, from a human or animal, preferably a human or animal in need thereof, comprising, absorbing the fluid with the scented and/or flavoured cotton or cotton product.
  • the scented and/or flavoured cotton or cotton product absorbs the fluid in the mouth or oral cavity of the human or animal, preferably the human or animal in need thereof.
  • the inventive embodiments include a method of protecting a surface of a human or animal, preferably a human or animal in need thereof, from contact with a fluid or other substance, the method comprising contacting the surface to be protected with the scented and/or flavoured cotton or cotton product.
  • the fluid can, for example, be saliva, blood, and /or water
  • the other substance can be, for example, a dental adhesive, a dental sealant, and /or a dental cement
  • the surface to be protected can be, for example, the tongue, a cheek, a tooth, a portion of a tooth, a crown surface, a filling surface, a tooth are that includes a hole, a nose, a torso, a nose and a mouth, and/or a gum.
  • the human, or human in need thereof may be, for example, a dentist or a patient, or a dental assistant, such as a dental hygienist, or x-ray technician; and the scented and/or flavoured cotton product can be, for example, a cotton roll, a cotton beam, a cotton mask, a cotton bib, a cotton cube a cotton strip, and /or a cotton pellet.
  • An animal includes, without limitation, a dog, a cat, a horse, a sheep, a cow, a donkey, an ape, a reptile, a lion, a tiger, a liger, a panda, a bear, a gazelle, a cheetah, a leopard, a hyena, a giraffe, a hippo, a beaver, a deer, a goat, an elk, a lama, and a pig.
  • a dog includes, without limitation, a dog, a cat, a horse, a sheep, a cow, a donkey, an ape, a reptile, a lion, a tiger, a liger, a panda, a bear, a gazelle, a cheetah, a leopard, a hyena, a giraffe, a hippo, a
  • an animal is a warm blooded animal.
  • the animal is a warm blooded animal excluding a human.
  • Scented and/or flavoured cotton or cotton products will give off scents even when they are dry.
  • a scented and/or flavoured cotton or cotton product gets wet in the patient's mouth, it will give off stronger flavour.
  • the strength of the flavour can be controlled by the amount of the scent in the solution during the manufacturing process of the scented and/or flavoured cotton or cotton products.
  • a scented cotton comprising a scent.
  • the sweetener is selected from sorbitol, sodium saccharine, saccharine, acesulfame potassium, sucralose, erythritol, a hydrogenated starch hydrolysate, isomalt, lactitol, maltitol, mannitol, xylitol, stevia, and combinations thereof.
  • the scented cotton roll of embodiment 10 wherein the colour is selected from the group consisting of red, orange, yellow, green, blue, cyan, indigo, violet, white, brown, black, and combinations thereof. 12) The scented cotton roll of embodiment 10, wherein the scented cotton roll comprises a colouring selected from FD&C Blue No. 1 , FD&C Blue No. 2, FD&C Green No. 3, FD&C Red No. 40, FD&C Red No. 3, FD&C Yellow No. 5, FD&C Yellow No. 6, and combinations thereof.
  • a method of protecting a surface in the mouth of a subject in need thereof comprising, contacting the surface with the scented cotton roll of embodiment 2, thereby protecting the surface of the subject in need thereof.
  • a method of absorbing a fluid in the mouth of a subject in need thereof comprising, absorbing the fluid from the mouth of the subject in need thereof with the scented cotton roll of embodiment 2.
  • a method of making the scented cotton roll of embodiment 2 comprising contacting a cotton roll with a scent to form the scented cotton roll. 22) A method of conducting a dental procedure, the method comprising conducting the dental procedure with the scented cotton roll of embodiment 2.
  • a method of masking or partially masking an undesired smell created during a dental procedure for a person or animal in need thereof comprising conducting the dental procedure with the scented cotton roll of embodiment 2, thereby masking or partially masking the undesired smell for the person in need thereof.
  • a method of conducting a dental procedure comprising conducting the dental procedure with the scented cotton of embodiment 1 or the flavoured cotton of embodiment 31 .
  • a method of protecting a surface in the mouth of a subject in need thereof comprising, contacting the surface with the scented cotton of embodiment 1 or the flavoured cotton of embodiment 3 1 , thereby protecting the surface in the mouth of the subject in need thereof.
  • a method of making the scented cotton of embodiment 1 comprising contacting a cotton with a scent to form the scented cotton.
  • a flavoured cotton comprising a taste ingredient.
  • a method of making the flavoured cotton of embodiment 31 comprising contacting a cotton with a taste ingredient to form the flavoured cotton.
  • Example 1 Preparation of a colored, sweetened, and scented / flavoured cotton roll
  • Cylindrical cotton rolls (Manufacturer Pearson Cotton Rolls- Mfg Part # 96-9125) in a standard size of 1 1 /2" x 3/8" were dipped / immersed into a solution comprising: thymol (0.064% by weight, based on the weight of the solution), eucalyptol (0.092% by weight, based on the weight of the solution), methyl salicylate (0.060% by weight, based on the weight of the solution), menthol (0.042% by weight, based on the weight of the solution, alcohol (21 .6%) by weight, based on the weight of the solution), with the remaining ingredients, being water, sorbitol, flavoring, poloxamer 407, benzoic acid, sodium saccharin, sodium benzoate, and FD&C Green 3 (e.g., Listerine Cool Mint).
  • the dipped / immersed cotton rolls were air dried at room temperature, to produce the coloured, sweetened and scented/flavoured
  • Example 1 Three human adults were presented with a coloured, sweetened and scented/flavoured cotton roll from Example 1 , supra. The human adults were previously exposed to a standard white cotton roll. The human adults examined and sniffed the coloured, sweetened and scented/flavoured cotton roll. All three humans indicated a preference for the coloured, scented/flavoured, sweetened cotton roll as compared to the standard white cotton roll.

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Abstract

The invention relates to a scented and/or flavoured and/or colored and/or taste altered cotton and products made therefrom, methods of making the cotton and the cotton products, and methods of using the cotton and cotton products.

Description

SCENTED AND/OR FLAVOURED COTTON AND PRODUCTS THEREFROM
BACKGROUND OF THE INVENTION
FIELD OF THE INVENTION
The invention relates to a scented and/or flavoured cotton, methods of making the cotton, and methods of using the cotton. The cotton may be used in the field of dentistry.
DISCUSSION OF THE BACKGROUND
Dental procedures can engender anxiety and /or fear in dental patients. Dental procedures include, without limitation, drilling, cavity / carries removal, tooth filling, tooth crowning, root-canals, tooth removal / extraction, implants, brushing, picking, and flossing. These and other dental procedures can result in bleeding and/or the production of saliva in the oral cavity of the dental patient, who can be a human or an animal. To control / contain the saliva and / or blood, cotton products are often employed. The cotton products are usually dry cotton products.
Cotton products, for example cotton rolls, are frequently used during dental work by dentists to dry a tooth, to absorb fluid (e.g., saliva, blood, water) in the patient's mouth, to prevent an oral surface from being contacted by water, saliva, blood or other fluid, or to shield a surface from coming into contact with, for example, a dental adhesive, a dental sealant, and /or a dental cement. Cotton rolls are typically placed between the tongue and teeth and/or gum, and between the cheek and teeth and/or gum to allow a surface to remain isolated and dry. In addition, dental patients are oftentimes asked to bite down on cotton rolls after a crown is installed to keep it in the proper position. These dental cotton rolls do not have any scents and/or flavours. Representative dry dental cotton rolls are shown in Fig. 1.
Because the dental procedures can be stressful, unpleasant, anxiety producing, fear engendering, and/or painful, it is desirable to find ways to make dental procedures more enjoyable. Decreasing the stress, unpleasantness, anxiety, fear and/or pain associated with a dental visit, a desirable goal in and of itself, can also facilitate better long term oral health by, for example, making patients more likely to visit a dentist on a regular basis, and, by making it more likely that a patient will undergo, when needed, dental procedure(s).
Flavour is the sensory impression of a substance, such as a cotton product, and is determined mainly by the chemical senses of taste and smell. A flavourant gives a substance flavour; smell is a main determinant of a substance's flavour. Thus, smell and flavour are intimately intertwined; and flavour of a substance easily altered by changing its smell (e.g., by changing its scent). While the taste of a substance is believed to be limited to the basic tastes of, for example, sweet, sour, bitter, salty, and savory, and combinations thereof, the number of smells that can be imparted to a substance is significantly greater. A substance's flavour, therefore, can be altered by changing its smell / scent.
The present inventors determined that one way to decrease the stress, unpleasantness, anxiety, fear and/or pain associated with a dental visit can be, for example, to impart a scent and/or flavour to a cotton or cotton product that can be used, for example, in a dental procedure, thus giving rise to the inventive embodiments described herein. BRIEF DESCRIPTION OF THE DRAWINGS
Figure 1 shows standard dry dental cotton rolls.
Figure 2 shows a right circular cylinder, a shape which the inventive cotton may adopt. Figure 3 shows a beam, a shape which the inventive cotton may adopt.
Figure 4 shows a unscented / unflavoured cotton roll (top) and a scented / flavoured, sweetened and colored cotton roll (bottom).
DETAILED DESCRIPTION OF THE INVENTION
The inventive cotton may be, for example, a dental cotton product that can be dry or can be wet (e.g., can contain a liquid absorbed therein).
The cotton employed in the inventive embodiments is preferably cotton that has been removed from a cotton boll (e.g., the rounded seed pod of the cotton plant), and further preferably cleaned, and further, preferably ginned (e.g., the cotton fibers are separated from, for example, the cotton seeds and/or stems). Further, the cotton employed in the inventive embodiments can be cotton where cotton fibers have been carded (e.g., aligned) and spun for form for example, threads. Additionally, the cotton threads can be woven into a fabric that can be employed in the inventive embodiments, or spun into a yarn that can be employed in the inventive embodiments. The type of cotton is not limited and can be, for example, American, Brazilian, Peruvian, Egyptian, and/or Asiatic cotton. The cotton can be, for example, a natural cotton and/or a genetically modified cotton. The cotton can be, for example, a shiny cotton. The cotton can be, for example, in the form of a fiber and/or a yarn. When the cotton in the form of fibers, without being limiting, the cotton fibers can range in width, for example, from 1 to 100 micrometers, preferably, 12-20 micrometers, including all values, ranges, and subranges therebetween. The cotton fibers, without being limiting, can range in length, for example, from 1 cm to 20 cm, preferably 1 cm to 6 cm, more preferably 2.2 cm to 3.3 cm in length, including all values, ranges, and subranges therebetween. The luster of the cotton fibers can be for example, low, medium and/or high luster, and is preferably high luster. The tenacity (strength) of the cotton fibers can be, without being limiting, when wet, for example, 1.0 - 10.0 g/d, preferably 3.0-5.0 g/d, including all values, ranges, and subranges therebetween. The tenacity (strength) of the cotton fibers can be, without being limiting, when dry, for example, 1 .0 - 20.0 g/d, preferably 3.3-6.0 g/d, including all values, ranges and subranges therebetween. The mositure absorption of the cotton fibers can be, without being limiting, for example, can range from 1 % to 30% including all values, ranges, and subranges therebetween.
While the cotton or cotton product is not limited in shape or form, examples of the cotton product include cotton balls, cotton strips, cotton pellets, cotton beams, cotton cubes, and cotton rolls; a cotton roll is a preferred cotton product. A further version of the cotton product includes the cotton tip on an applicator (e.g., a small wad of cotton wrapped around one or both ends of a rod, the rod comprising, for example, wood, plastic, rolled paper, a metal, and/or combinations of these materials). Additional variations of the cotton product include a cotton gauze (e.g., a thin, translucent fabric with a loose open weave), a cotton bandage, a cotton bib, and a cotton face mask. In one embodiment, the cotton component is a non-woven cotton. In another embodiment, the cotton product is not in the form of a filament (e.g., thread). In another embodiment, the cotton product is in the form of a filament. It is understood that a face mask includes a mask component and optionally an attachment component (for example, a piece of elastic and/or or an adhesive strip), and that a cotton bib includes a bib component and optionally an attachment component (such as a plastic or metal or elastic strip or wire with fasteners, such as clamps or snaps or buttons, at each end of the strip or wire, that attach to the bib). A face mask includes variations where the mask component of the face mask covers both the nose and the mouth, covers the nose, covers a potion of the nose, or covers all or part of the area between the nose and the mouth. The mask is employed by placing the mask on the face of a person or animal, preferably a person or animal in need thereof, such that it covers the nose, the mouth, a portion of the nose, or all or part of the area between the nose and mouth. The mask may be employed, for example, on a patient, preferably a patient in need thereof, a dentist, preferably a dentist in need thereof, or other dental professional such as a dental hygienist, preferably a dental hygienist in need thereof. The mask may, for example, when employed, mask the breath of the person or animal for to which the mask is employed, and may, for example, mask bad breath or halatosis.
A roll is cylindrically shaped. The cylinder can have, for example, without being limited, a cross section that is an ellipse, parabola, or hyperbola, or circle. In a preferred embodiment, the roll is a right circular cylinder, with its ends being two circular surfaces. The right circular cylinder has a height, h, and a diameter, d, as shown in Fig. 2.
The height, h, without being limiting, for example, can range from 1 nm to 50 cm, including all ranges, subranges, and values therebetween. Thus, the height, h, can be, for example, 1 nm, 10, nm, 100 nm, 200 nm, 300 nm, 400 nm, 500 nm, 600 nm, 700 nm, 800 nm, 900 nm, 1 μιη, 2 μηι, 3 μιτι, 4 μπι, 5 μηι, 6 μιτι, 7 μιη, 8 μηι, 9 μηι, 10 μηι, 50 μπι, 100 μιη, 200 μηι, 300 μηι, 400 μιη, 500 μηι, 600 μηι, 700 μιη, 800 μηι, 900 μηι, 1 mm, 2 mm, 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 8 mm, 9 mm, 10, mm, 50 mm, 100 mm, 200 mm, 300 mm, 400 mm, 500 mm, 600 mm, 700 mm, 800 mm, 900 mm, 1 cm, 2 cm, 3 cm, 4 cm, 5 cm, 6 cm, 7 cm, 8 cm, 9 cm, 10 cm, 1 1 cm, 12 cm, 13 cm, 14 cm, 15 cm, 16 cm, 17 cm, 18 cm, 19 cm, 20, cm, 25 cm, 30 cm, 35 cm, 40 cm, 45 cm, or 50 cm. The diameter, d, for example, without being limiting can range from 1 nm to 50 cm, including all ranges, subranges, and values therebetween. Thus, the diameter, d, can be, for example, 1 nm, 10, nm, 100 nm, 200 nm, 300 nm, 400 nm, 500 nm, 600 nm, 700 nm, 800 nm, 900 nm, 1 μηι, 2 μηι, 3 μιη, 4 μηι, 5 μηι, 6 μηι, 7 μιτι, 8 μηι, 9 μιη, 10 μιη, 50 μηι, 100 μηι, 200 μπι, 300 μπι, 400 μηι, 500 μιη, 600 μηι, 700 μηι, 800 μηι, 900 μηι, 1 mm, 2 mm, 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 8 mm, 9 mm, 10, mm, 50 mm, 100 mm, 200 mm, 300 mm, 400 mm, 500 mm, 600 mm, 700 mm, 800 mm, 900 mm, 1 cm, 2 cm, 3 cm, 4 cm, 5 cm, 6 cm, 7 cm, 8 cm, 9 cm, 10 cm, 1 1 cm, 12 cm, 13 cm, 14 cm, 15 cm, 16 cm, 17 cm, 18 cm, 19 cm, 20, cm, 25 cm, 30 cm, 35 cm, 40 cm, 45 cm, or 50 cm.
In another embodiment, the cotton product is in the shape of a beam. A beam has a length, 1, height, h, and width, w, as shown in Fig. 3.
The height, h, for example, without being limiting can range from 1 nm to 50 cm, including all ranges, subranges, and values therebetween. Thus, the height, h, can be, for example, 1 nm, 10, nm, 100 nm, 200 nm, 300 nm, 400 nm, 500 nm, 600 nm, 700 nm, 800 nm, 900 nm, 1 μιη, 2 μηι, 3 μιτι, 4 μηι, 5 μιη, 6 μηι, 7 μιη, 8 μιη, 9 μηι, 10 μηι, 50 μηι, 100 μηι, 200 μηι, 300 μηι, 400 μηι, 500 μηι, 600 μπι, 700 μηι, 800 μηι, 900 μπι, 1 mm, 2 mm, 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 8 mm, 9 mm, 10, mm, 50 mm, 100 mm, 200 mm, 300 mm, 400 mm, 500 mm, 600 mm, 700 mm, 800 mm, 900 mm, 1 cm, 2 cm, 3 cm, 4 cm, 5 cm, 6 cm, 7 cm, 8 cm, 9 cm, 10 cm, 1 1 cm, 12 cm, 13 cm, 14 cm, 15 cm, 16 cm, 17 cm, 18 cm, 19 cm, 20, cm, 25 cm, 30 cm, 35 cm, 40 cm, 45 cm, or 50 cm. The length, 1, for example, without being limiting can range from 1 nm to 50 cm, including all ranges, subranges, and values therebetween. Thus, the length, 1, without being limiting can be, for example, 1 nm, 10, nm, 100 nm, 200 nm, 300 nm, 400 nm, 500 nm, 600 nm, 700 nm, 800 nm, 900 nm, 1 μιη, 2 μηι, 3 μιη, 4 μιη, 5 μιη, 6 μπι, 7 μπι, 8 μηι, 9 μιη, 10 μηι, 50 μηι, 100 μηι, 200 μηι, 300 μm, 400 μηι, 500 μηι, 600 μηι, 700 μm, 800 μιη, 900 μιτι, 1 mm, 2 mm, 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 8 mm, 9 mm, 10, mm, 50 mm, 100 mm, 200 mm, 300 mm, 400 mm, 500 mm, 600 mm, 700 mm, 800 mm, 900 mm, 1 cm, 2 cm, 3 cm, 4 cm, 5 cm, 6 cm, 7 cm, 8 cm, 9 cm, 10 cm, 1 1 cm, 12 cm, 13 cm, 14 cm, 15 cm, 16 cm, 17 cm, 18 cm, 19 cm, 20, cm, 25 cm, 30 cm, 35 cm, 40 cm, 45 cm, or 50 cm. The width, w, for example, without being limiting can range from 1 nm to 50 cm, including all ranges, subranges, and values therebetween. Thus, the width, w, can be, for example, 1 nm, 10, nm, 100 nm, 200 nm, 300 nm, 400 nm, 500 nm, 600 nm, 700 nm, 800 nm, 900 nm, 1 μηι, 2 μιη, 3 μπι, 4 μηα, 5 μηι, 6 μηι, 7 μηι, 8 μηι, 9 μπι, 10 μιτι, 50 μηι, 100 μηι, 200 μηι, 300 μιη, 400 μηι, 500 μηι, 600 μηι, 700 μηι, 800 μηι, 900 μηι, 1 mm, 2 mm, 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 8 mm, 9 mm, 10, mm, 50 mm, 100 mm, 200 mm, 300 mm, 400 mm, 500 mm, 600 mm, 700 mm, 800 mm, 900 mm, 1 cm, 2 cm, 3 cm, 4 cm, 5 cm, 6 cm, 7 cm, 8 cm, 9 cm, 10 cm, 1 1 cm, 12 cm, 13 cm, 14 cm, 15 cm, 16 cm, 17 cm, 18 cm, 19 cm, 20, cm, 25 cm, 30 cm, 35 cm, 40 cm, 45 cm, or 50 cm.
The cotton or cotton product can have a weight, without being limiting, ranging from, for example, 0.1 ng to lOOg, including all ranges, values and subranges therebetween. The cotton product can, without being limiting, weigh, for example 1 ng, 10 ng, 100 ng, 500 ng, 1 μ¾, 10 μ¾, 100 μ8, 500 μ , 1 mg, 10 mg, 100 mg, 500 mg, 1 g, 5 g, 10 g, 25 g, or 50 g.
It is understood that the cotton product, in addition to comprising cotton, may comprise other materials, either alone or in combination, including, but not limited to, a rubber, a silicone, a silk, a polysaccharide in addition to the polysaccharide(s) that naturally comprise cotton, a polyester, a polyamide, a polyurethane, a polycarbonate, a polystyrene, a thermoplastic polymer, a nucleic acid polymer, such as DNA or RNA, polyethylene, polypropylene, polybutylene, a copolymer, which may, for example, be a block copolymer or a random copolymer, a cellulose nitrate, a cellulose acetate, a polyvinyl chloride, and combinations of these materials. Any of these materials, alone or in combination, can be comprised, for example, in the form of threads. In one embodiment, the cotton product does not comprise any of the materials listed in this paragraph. In another embodiment, the cotton product does not comprise any polymer other than the polymer(s) naturally found in cotton.
The flavour and / or scent the cotton or cotton product comprises, when comprising a flavour and/or scent, is not limited to any particular flavour / scent or combinations of flavours / scents. Examples of flavours and/or scents include, but are not limited to, lemon, lime, coffee, peach, jasmine, mint, peppermint, honey, root beer, wintergreen, orange, fruity, rum, coffee, chocolate, cocoa, butter, cream, cherry, apricot, grape, pineapple, pear, strawberry, jasmine, cinnamon, vanilla, almond, apple, marshmallow, banana, strawberry, bubble gum, raspberry, pepper, tea, caramel and combinations of these flavours / scents.
The following inventive embodiments, without being limiting, are examples of flavours and / or scents that the cotton or cotton product can comprise:
In one inventive embodiment, the cotton product can be pineapple scented and/or flavoured by allyl hexanoate, alone or in combination with other scents and/or flavors.
In one inventive embodiment, the cotton or cotton product can be pear and/or strawberry and/or jasmine scented and/or flavoured by benzyl acetate, alone or in combination with other scents and/or flavors. In one inventive embodiment, the cotton or cotton product can be banana and/or pineapple and/or strawberry scented and/or flavoured by ethyl butyrate, alone or in
combination with other scents and/of flavors.
In one inventive embodiment, the cotton or cotton product can be strawberry scented and/ or flavoured by ethyl hexanoate, alone or in combination with other scents and/or flavors.
In one inventive embodiment, the cotton or cotton product can be pineapple scented by butyl butyrate, alone or in combination with other scents and/or flavors.
In one inventive embodiment, the cotton or cotton product can be cinnamon scented and/or flavoured by ethyl cinnamate, alone or in combination with other scents and/or flavors.
In one inventive embodiment, the cotton or cotton product can be lemon and/or rum and/or raspberry and/or strawberry scented and/or flavoured by ethyl formate, alone or in combination with other scents and/or flavors.
In one inventive embodiment, the cotton or cotton product can be apricot and/or cherry and/or raspberry and/or grape scented and/or flavoured by ethyl heptanoate, alone or in combination with other scents and/or flavors.
In one inventive embodiment, the cotton or cotton product can be apple scented and/or flavoured by ethyl isovalerate, alone or in combination with other scents and/or flavors.
In one inventive embodiment, the cotton or cotton product can be butter and/or cream scented and/or flavoured by ethyl lactate, alone or in combination with other scents and/or flavors.
In one inventive embodiment, the cotton or cotton product can be grape scented and/or flavoured by ethyl nonanoate, alone or in combination with other scents and/or flavors. In one inventive embodiment, the cotton or cotton product can be apple scented and/or flavoured by ethyl pentanoate, alone or in combination with other scents and/or flavors.
In one inventive embodiment, the cotton or cotton product can be cherry scented and/or flavoured by geranyl butyrate, alone or in combination with other scents and/or flavors.
In one inventive embodiment, the cotton or cotton product can be apple scented and/or flavoured by geranyl pentanoate, alone or in combination with other scents and/or flavors.
In one inventive embodiment, the cotton or cotton product can be chocolate and/or cocoa and/or coffee scented and/or flavoured by 2,5-dimethylpyrazine, alone or in
combination with other scents and/or flavors.
In one inventive embodiment, the cotton or cotton product can be cherry and/or strawberry and/or raspberry scented and/or flavoured by isobutyl acetate, alone or in combination with other scents and/or flavors.
In one inventive embodiment, the cotton or cotton product can be honey scented and/or flavoured by methyl phenyl acetate, alone or in combination with other scents and/or flavors.
In one inventive embodiment, the cotton or cotton product can be root beer and/or wintergreen scented and/or flavoured by methyl salicylate, alone or in combination with other scents and/or flavors.
In one inventive embodiment, the cotton or cotton product can be orange scented and/or flavoured by nonyl caprylate, alone or in combination with other scents and/or flavors. In one inventive embodiment, the cotton or cotton product can be scented by vanillin (e.g.,4-hydroxy-3- methoxy benzaldehyde), alone or in combination with other scents and/or flavors.
In another inventive embodiment, the cotton or cotton product can be scented and/or flavored by benzaldehyde (e.g., almond scented and/or flavored), alone or in combination with other scents and/or flavours.
In a further inventive embodiment, the cotton or cotton product can be popcorn scented and/or flavored by employing methyl-2-pyridyl ketone, alone or in combination with other scents and/or flavors.
In another inventive embodiment, the cotton or cotton product can be apple scented and /or flavoured by employing ethyl-2-methyl butyrate, alone or in combination with other scents and / or flavors.
In one inventive embodiment, the cotton or cotton product can be marshmallow scented and/or flavoured by employing ethyl-3-hydroxy butanoate, alone or in combination with other scents and / or flavors.
In one inventive embodiment, the cotton or cotton product can be banana and/or pear scented and /or flavoured by employing banana oil (e.g., isoamyl acetate), alone or in combination with other scents and /or flavours.
In one inventive embodiment, the cotton or cotton product can be strawberry scented and / or flavoured by employing strawberry oil (e.g., ethyl methylphenylglycidate), alone or in combination with other scents and / or flavours. In one inventive embodiment, the cotton or cotton product can be bubble gum scented and / or flavoured by employing prenyl acetate (e.g., 3-methyl-2-butenyl acetate), alone or in combination with other scents and / or flavours.
Additional scents and/or flavours, that can be used alone or in combination with any other scent and /or flavour include, but are not limited to, for example, isobutyl formate, isopropyl acetate, linalyl acetate, linalyl butyrate, linalyl formate, methyl acetate, methyl anthranilate, methyl benzoate methyl benzyl acetate, methyl butyrate, methyl cinnamate, methyl pentanoate, octyl acetate, octyl butyrate, amyl acetate, amyl butyrate, pentyl hexanoate, pentyl pentanoate, propyl ethanoate, propyl isobutyrate, and terpenyl butyrate.
The amount of each of these scents and/or flavours, individually, comprised in the cotton or cotton product (e.g., into or onto the surface of the cotton or cotton product, or a portion thereof, or the interior of the cotton or cotton product, or a portion thereof, or a portion of the cotton or cotton product, or the cotton or cotton product as a whole) is not limited and can range, for example, from 0.1 ng to 10 g, including all values, ranges, and subranges therebetween. For example, the amount can be 10 ng, 25 ng, 50 ng, 75 ng, 100 ng, 200 ng, 300 ng, 400 ng, 500 ng, 600 ng, 700 ng, 800 ng, 900 ng, 1 μg, 2 μg, 3μ§, 4 μ§, 5 μδ, 6 μδ, 7 μ8, 8 μβ, 9 μ§, 10 μ§, 25 μ§, 50 μδ, 75 μ§, 100 μ§, 200 μ§, 300 μ§, 400 μ§, 500 μ§, 600 μg, 700 μg, 800 μg, 900 μg, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg, 80 mg, 90 mg, 100 mg, 200 mg, 300 mg, 400 mg, 500 mg, 600 mg, 700 mg, 800 mg, 900 mg, 1 g, 2 g, 3 g, 4 g, 5 g, 6 g, 7g, 8g, 9 g or 10 g.
The amount of any scent and /or flavour preferably can be detected by human taste and/or smell. In a further inventive embodiment, the cotton or cotton product can contain a taste ingredient, alone or in combination, that imparts a taste of at least one of sweet, sour, bitter, salty, and and/or savory (e.g., a sweetener, a souring ingredient, a salt, a bittering ingredient, and /or a savory ingredient). In one embodiment, the cotton or cotton product does not comprise an added taste ingredient that imparts a taste of at least one of sweet, sour, bitter, salty, and and/or savory.
For example, the cotton or cotton product can comprise one or more sweeteners, either alone or in combination. Non-limiting examples of sweeteners include aspartame, saccharine, acesulfame k (e.g, potassium), sucralose, erythritol, hydrogenated starch hydrolysates, isomalt, lactitol, maltitol, mannitol, sorbitol, xylitol, and stevia. The one or more sweeteners can each, be employed, individually or in combination of two or more. The amount of each sweetener comprised in the cotton or cotton product is not limited and can range, for example, from 0. 1 ng to 1 g, including all values, ranges, and subranges therebetween. For example, the amount can be 1 ng, 10 ng, 25 ng, 50 ng, 75 ng, 100 ng, 200 ng, 300 ng, 400 ng, 500 ng, 600 ng, 700 ng, 800 ng, 900 ng, 1 μg, 2 μg, 3μg, 4 μg, 5 μg, 6 g, 7 μg, 8 μg, 9 μg, 10 μg, 25 μ , 50 75 μ , 100 μg, 200 μδ, 300 μδ, 400 μ¾, 500 μδ, 600 μ§, 700 μ§, 800 μ§, 900 μ§, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 nig, 7 mg, 8 mg, 9 mg, 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg, 80 mg, 90 mg, 100 mg, 200 mg, 300 mg, 400 mg, 500 mg, 600 mg, 700 mg, 800 mg, 900 mg, or 1 g.
In an additional embodiment, the cotton or cotton product can comprise one or more salts. Salts include, for example, magnesium chloride, potassium chloride, calcium chloride, monosodium glutamate, sodium fluoride, potassium fluoride, and/or sodium chloride. The salts can be cationic metal salts of an organic anion and /or an inorganic anion. The amount of each salt comprised in the cotton or cotton product is not limited and can range, for example, from 0.1 ng to 1 g, including all values, ranges, and subranges therebetween. For example, the amount can be 1 ng, 10 ng, 25 ng, 50 ng, 75 ng, 100 ng, 200 ng, 300 ng, 400 ng, 500 ng, 600 ng, 700 ng, 800 ng, 900 ng, 1 μg, 2 μg, ^g, 4 μδ, 5 μβ, 6 μδ, 7 μg, 8 μ& 9 μ¾, 10 μg, 25 μg, 50 μδ, 75 μ§, 100 μg, 200 μ§, 300 μg, 400 μg, 500 μ§, 600 μg, 700 μ§, 800 μ¾, 900 μg, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg, 80 mg, 90 mg, 100 mg, 200 mg, 300 mg, 400 mg, 500 mg, 600 mg, 700 mg, 800 mg, 900 mg, or 1 g.
In a further embodiment, the cotton or cotton product can comprise one or more souring ingredients. Souring ingredients, for example, such as citric acid, a salt thereof (such as sodium, potassium, calcium or magnesium citrate), an ester thereof (such as triethyl citrate), vitamin c (e.g., ascorbic acid, L-ascorbic acid), and /or a salt thereof (such as sodium, potassium, calcium or magnesium ascorbate), and combinations thereof. The amount of each souring ingredient comprised in the cotton or cotton product is not limited and can range, for example, from 0.1 ng to 1 g, including all values, ranges, and subranges therebetween. For example, the amount can be 1 ng, 10 ng, 25 ng, 50 ng, 75 ng, 100 ng, 200 ng, 300 ng, 400 ng, 500 ng, 600 ng, 700 ng, 800 ng, 900 ng, 1 μg, 2 μ§, 3μg, 4 μg, 5 μ& 6 μ§, 7 μ§, 8 μ§, 9 μg, 10 μδ, 25 μ¾, 50 μ§, 75 μ8, 100 μ&, 200 μ§, 300 μ8, 400 μδ, 500 μ§, 600 μg, 700 μ§, 800 μδ, 900 μg, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg, 80 mg, 90 mg, 100 mg, 200 mg, 300 mg, 400 mg, 500 mg, 600 mg, 700 mg, 800 mg, 900 mg, or 1 g.
In a further embodiment, the cotton or cotton product can comprise one or more bittering ingredients, such as quinine, or a salt thereof, such as an HC1 salt, or any pharmacologically acceptable salt of quinine or of the bittering agent. The amount of each bittering agent comprised in the cotton or cotton product is not limited and can range, for example, from 0.1 ng to 1 g, including all values, ranges, and subranges therebetween. For example, the amount can be 1 ng, 10 ng, 25 ng, 50 ng, 75 ng, 100 ng, 200 ng, 300 ng, 400 ng, 500 ng, 600 ng, 700 ng, 800 ng, 900 ng, 1 μβ, 2 μβ, 3μ , 4 μ , 5 μβ, 6 μβ, 7 μβ, 8 μg, 9 μg, 10 μg, 25 μg, 50 μδ, 75 μ§, 100 μ§, 200 μ§, 300 μg, 400 μ§, 500 μβ, 600 μδ, 700 μ§, 800 μ§, 900 μg, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg, 80 mg, 90 mg, 100 mg, 200 mg, 300 mg, 400 mg, 500 mg, 600 mg, 700 mg, 800 mg, 900 mg, or 1 g.
In a further embodiment, the cotton or cotton product can comprise at least one of an antiseptic, an antibiotic, an antifungal, a cleaning agent, a local anesthetic, a preservative, a surfactant, such as a poloxamer, and /or combinations thereof. The amount of each antiseptic, antibiotic, antifungal, cleaning agent, and local anesthetic that can be comprised in the cotton or cotton product is not limited and can be present in an amount ranging, for example from from 0.1 ng to 10 g, including all values, ranges, and subranges therebetween. For example, the amount can be 1 ng, 10 ng, 25 ng, 50 ng, 75 ng, 100 ng, 200 ng, 300 ng, 400 ng, 500 ng, 600 ng, 700 ng, 800 ng, 900 ng, 1 μg, 2 μg, 3μ§, 4 μg, 5 μg, 6 μ& 1 μ§, 8 μg, 9 μ§, 10 μg, 25 μ¾, 50 μ¾, 75 μ¾, 100 μg, 200 μ§, 300 μg, 400 μ& 500 μβ, 600 μ§, 700 μ§, 800 μ§, 900 μg, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg, 80 mg, 90 mg, 100 mg, 200 mg, 300 mg, 400 mg, 500 mg, 600 mg, 700 mg, 800 mg, 900 mg, 1 g, or l O g.
In one embodiment, the cotton or cotton product does not comprise any of an antiseptic, an antibiotic, an antifungal, a cleaning agent, a local anesthetic, a surfactant, a preservative, and /or combinations thereof. Examples of these substances include menthol, thymol, methyl silicylate, eucalyptol, and cetylpyridinium chloride.
In one embodiment, the cotton or cotton product can comprise a fluoride comprising compound. Examples of the fluoride comprising compound include, for example, sodium fluoride, hexafluorosilicic acid, (H2SiF6), sodium hexafluorosilicate (Na2SiF6), and combinations thereof. Each fluoride comprising compound, can be, for example,
individually comprised in the cotton or cotton product and the amount is not limited and can be in an amount ranging, for example, from from 0.1 ng to 1 g, including all values, ranges, and subranges therebetween. For example, the amount can be 1 ng, 10 ng, 25 ng, 50 ng, 75 ng, 100 ng, 200 ng, 300 ng, 400 ng, 500 ng, 600 ng, 700 ng, 800 ng, 900 ng, 1 μg, 2 μβ, 3μg, 4 μg, 5 μδ, 6 μg, 7 μg, 8 μg, 9 μ& 10 μg, 25 μg, 50 μ§, 75 μδ, 100 μ§, 200 μg, 300 μg, 400 μg, 500 μg, 600 μg, 700 μg, 800 μg, 900 μg, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg, 80 mg, 90 mg, 100 mg, 200 mg, 300 mg, 400 mg, 500 mg, 600 mg, 700 mg, 800 mg, 900 mg, or 1 g.
In one embodiment, the cotton or cotton product comprises menthol, thymol, methyl silicylate, and eucalyptol. In one embodiment, a solution comprising alcohol (such as ethanol) in an amount of 26.1 % by weight, based on the weight of the solution, eucalyptol in an amount of 0.092% by weight, based on the weight of the solution, menthol in an amount of 0.042% by weight, based on the weight of the solution, methyl salicylate, in an amount of 0.060% by weight, based on the weight of the solution, and thymol in an amount of 0.064%o by weight, based on the weight of the solution, with the remainder of the solution being water and /or other ingredients, is employed as a spraying or dipping solution for the cotton or cotton product, which, after spraying or dipping, can optionally be dried to reduce and /or remove the ethanol and / or water.
Examples of antibiotics include, but are not limited to, Amikacin, Gentamicin, Kanamycin Neomycin, Netilmicin, Streptomycin, Tobramycin, Paromomycin, Ansamycins, Geldanamycin, Herbimycin, Carbacephem, Loracarbef, Carbapenems, Ertapenem,
Doripenem, Imipenem/Cilastatin, Meropenem, Cephalosporins, Cefadroxil, Cefazolin, Cefalotin, Cefalothin, Cefalexin, Cephalosporins, Cefaclor, Cefamandole, Cefoxitin,
Cefprozil, Cefuroxime, Cephalosporins, Cefixime, Cefdinir, Cefditoren, Cefoperazone, Cefotaxime, Cefpodoxime, Ceftazidime, Ceftibuten, Ceftizoxime, Ceftriaxone,
Ceftobiprole, Glycopeptides, Teicoplanin, Vancomycin, Macrolides, Azithromycin,
Clarithromycin, Dirithromycin, Erythromycin, Roxithromycin, Troleandomycin,
Telithromycin, Spectinomycin, Monobactams, Aztreonam, Penicillins, Amoxicillin,
Ampicillin, Azlocillin, Carbenicillin, Cloxacillin, Dicloxacillin, Flucloxacillin,
Mezlocillin, Meticillin, Nafcillin, Oxacillin, Penicillin, Piperacillin, Ticarcillin,
Polypeptides, Bacitracin, Colistin, Polymyxin B, Quinolones, Ciprofloxacin, Enoxacin, Gatifloxacin, Levofloxacin, Lomefloxacin, Moxifloxacin, Norfloxacin, Ofloxacin,
Trovafloxacin, Grepafloxacin, Sparfloxacin, Sulfonamides, Mafenide,
Prontosil, Sulfacetamide, Sulfamethizole, Sulfanilimide, Sulfasalazine, Sulfisoxazole, Trimethoprim, Trimethoprim-Sulfamethoxazole (Co-trimoxazole), Tetracyclines
Demeclocycline, Doxycycline, Minocycline, Oxytetracycline, Tetracycline,
Arsphenamine, Chloramphenicol, Clindamycin, Lincomycin, Ethambutol, Fosfomycin, Fusidic acid, Furazolidone, Isoniazid, Linezolid, Metronidazole, Mupirocin, Nitrofurantoin, Platensimycin, Pyrazinamide, Quinupristin Dalfopristin, Rifampicin, Thiamphenicol, Tinidazole, and combinations thereof.
Examples of antifungals include, but are not limited to, Itraconazole, Ketoconazole, Fluconazole, Voriconazole, Nystatin, Flucytosine, Amphotericin B, Griseofulvin,
Terbinafine and combinations thereof.
Examples of local anesthetics include, but are not limited to,
Benzocaine, Chloroprocaine, Cocaine, Cyclomethycaine, Dimethocaine/Larocaine,
Propoxycaine, Procaine/Novocaine, Proparacaine, Tetracaine/Amethocaine,
Lidocaine, Articaine, Bupivacaine, Carticaine, Cinchocaine/Dibucaine, Etidocaine,
Levobupivacaine, Lidocaine/Lignocaine, Mepivacaine, Piperocaine, Prilocaine, Ropivacaine, Trimecaine, Lidocaine/prilocaine, Saxitoxin, Tetrodotoxin and combinations thereof.
The cotton or cotton product can be colored. Examples of colors include, but are not limited to, red, orange, yellow, green, blue, indigo, violet, white, brown, black, and combinations thereof. Examples of colorings that can be used to color the cotton orcotton product include, but are not limited to, FD&C Blue No. 1 - Brilliant Blue FCF, El 33 (Blue shade), FD&C Blue No. 2 - Indigotine, El 32 (Dark Blue shade), FD&C Green No. 3 - Fast Green FCF, E l 43 (Bluish green shade), FD&C Red No. 40 - Allura Red AC, El 29 (Red shade), FD&C Red No. 3 - Erythrosine, E127 (Pink shade), FD&C Yellow No. 5 - Tartrazine, E l 02 (Yellow shade), FD&C Yellow No. 6 - Sunset Yellow FCF, El 10 (Orange shade), and combinations thereof.
Any flavour / scent, color, taste ingredient, antifungal, antiseptic, local anesthetic, and/or cleaning agent, in short, any ingredient comprised in the cotton or cotton product, may, as appropriate, be comprised as a neutral molecule, such as an ester, a zwitterion, such as an amino acid, either D, L, or racemic, an acid, a base, a free base, or a salt, such as an organic or an inorganic salt, as appropriate. Any flavour / scent, color, taste ingredient, antifungal, antiseptic, local anesthetic, and/or cleaning agent, in short, any ingredient comprised in the cotton or cotton product, may, as appropriate, be chiral non-racemic, racemic, a diastereomer, or a geometric isomer.
Any ingredient, including but not limited to flavour(s) and/or scent(s), coloring agent(s), taste ingredient(s), antibiotic(s), and antifungal(s), individually, is not limited in the amount comprised in the cotton or cotton product, and can be comprised, on wt% basis relative to the total weight of the cotton or cotton product, in an amount ranging ranging, for example, from 0.00001 wt% to 99.99999 wt%, including all values, ranges, and subranges therebetween. For example, the ingredient can be comprised in the cotton product in 0.0001 wt%, 0.001 wt%, 0.01 wt%, 0.1 wt%, 1.0 wt%, 10 wt%, 20 wt%, 30 wt%, 40 wt%, 50 wt%, 60 wt%, 70 wt%, 80 wt%, or 90 wt%.
Any ingredient, including but not limited to flavour(s) and/or scent(s), coloring agent(s), taste ingredient(s), antibiotic(s), and antifungal(s), individually, is not limited in the amount comprised in the cotton or cotton product, and may be comprised in the cotton or cotton product, for example, in an amount ranging from 0.1 ng to 100 g, including all values, ranges, and subranges therebetween. For example, any ingredient can be comprised in an amount of 10 ng, 25 ng, 50 ng, 75 ng, 100 ng, 200 ng, 300 ng, 400 ng, 500 ng, 600 ng, 700 ng, 800 ng, 900 ng, 1 μg, 2 μg, 3μ , 4 μg, 5 μg, 6 μg, Ί μg, 8 μg, 9 Mg, 10 μg, 25 μg, 50 μg, 75 μg, 100 μg, 200 μ§, 300 μ§, 400 μg, 500 μδ, 600 μg, 700 μ§, 800 μ& 900 μg, 1 mg, 2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7 mg, 8 mg, 9 mg, 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg, 80 mg, 90 mg, 100 mg, 200 mg, 300 mg, 400 mg, 500 mg, 600 mg, 700 mg, 800 mg, 900 mg, 1 g, 2 g, 3 g, 4 g, 5 g, 6 g, 7g, 8g, 9 g, 10 g or l OOg. All of the above, including the flavour and /or scent and/or color and/or sweetener and/or taste ingredient and/or antiseptic and/or antifungal and/or antibacterial and/or local anesthetic and/or cleaning agent can be applied to a cotton or shaped cotton (e.g., applied to a cotton roll) to form the cotton product, or can be applied to a cotton material before the cotton material is shaped / formed into the cotton product (e.g., applied to a cotton, or a cotton fabric or cotton weave, before the cotton, fabric, or cotton weave is shaped into the cotton product such as a cotton roll). The method of applying the flavour and /or scent and/or color and/or sweetener and/or antiseptic and/or antifungal and/or antibacterial is not limited. The flavour and /or scent and/or color and/or sweetener and/or antiseptic and/or antifungal and/or antibacterial can be directly applied as a solid, for example as a powder, or an oil.
Alternatively, the flavour and /or scent and/or color and/or sweetener and/or antiseptic and/or antifungal and/or antibacterial can be applied dissolved or dispersed in a solution. The solution, without limits, can be a single solvent or a mixture of solvents, for example, a water solution, an ethanol solution, a supercritical carbon dioxide solution, or a mixture of these. Each ingredient in the solution can be contained, without being limiting, for example in a concentration ranging from 0.1 nanomolar to 10 molar, including all ranges, subranges, and values therebetween. For example, each ingredient can be contained in the solution in a concentration of 1 nanomolar, 10 nanomolar, 100 nanomolar, 500 nanomolar, 1 μι ο^Γ, 10 μι-nolar, 100 μι-nolar, 500 μηιο^Γ, 1 millmolar, 10 millimolar, 50 millimolar, 100 millimolar, 500 millimolar, 1 molar, 5 molar, and 10 molar. If applied as a solution, the solution can be applied, for example, by spraying or by dipping. If more than one ingredient is applied, the ingredients can be present in the same solution, or can be applied using separate solutions, at the same time or sequentially. The cotton or cotton product, after application of the solution, can be used wet or dried before use. Drying temperatures are not limited and drying can be conducted, for example, at a temperature ranging from -78 °C to 200 °C, including all values, ranges, and subranges therebetween. For example, drying can be conducted at - 10 °C, 0 °C, 10 °C, 20 °C, 30 UC, 40 °C, 50 °C, 60 °C, 70 "C, 80 °C, or 90 °C. The drying, without being limited, can be conducted under reduced pressure and/or vacuum, for example, from 0.99 atm to 0.000001 atm, including all values, ranges, and subranges therebetween. The cotton product can be sterile or can be unsterilized. Sterilizing the cotton product can be effected, for example, by heat, including dry heat, high pressure, and/or irradiation. In the alternative, the materials used in and/or to make the cotton or cotton product, including the cotton, can be sterilized prior to forming the cotton or cotton product, the formation of which can be done in a sterile environment, such as a clean room. The flavour and /or scent and/or color and/or sweetener and/or antiseptic and/or antifungal and/or antibacterial and/or taste ingredient can be applied, or any ingredient, for example, can be applied to at least a portion of at least one surface of the cotton or cotton product, can be applied to a surface of the cotton or cotton product, can be applied to all surfaces of the cotton or cotton product, can be applied to a portion of the interior of the cotton or cotton product, can be applied to the interior of the cotton or cotton product, can be applied to the surface and the interior of the cotton or cotton product, or combinations of these.
The flavour and /or scent and/or color and/or sweetener and/or antiseptic and/or antifungal and/or antibacterial and/or taste ingredient can be further applied with other materials such a lubricant, a glidant, a binder, an emulsifier, a filler, an excipient, and combinations of these materials. The inventive embodiments include a method of placing the scented and/or flavoured cotton or cotton product into the oral cavity of a human or animal, preferably a human or animal in need thereof, comprising introducing the scented and/or flavoured cotton or cotton product into the oral cavity of the human or animal.
The inventive embodiments include a method of inducing experiencing of a scent and/or flavour and/or taste in a human or animal, preferably a human or animal in need thereof, comprising, placing the scented and/or flavoured cotton or cotton product into the oral cavity of the human or animal.
The inventive embodiments include a method of inducing experiencing of a scent and/or flavour and/or taste in a human or animal, collectively animals including humans are subjects, preferably a human or animal or subject in need thereof, comprising, placing the scented and/or flavoured cotton or cotton product over the space between the mouth and nose, of the human or animal.
The inventive embodiments include a method of inducing recognition of a scent and/or flavour and/or taste in a human or animal, preferably a human or animal in need thereof, comprising, placing the scented and/or flavoured cotton or cotton product over the nose or of the human or animal, preferably a human or animal in need thereof.
The inventive embodiments include a method of absorbing a fluid, preferably blood, saliva, or water, from a human or animal, preferably a human or animal in need thereof, comprising, absorbing the fluid with the scented and/or flavoured cotton or cotton product. In additional inventive embodiments, the scented and/or flavoured cotton or cotton product absorbs the fluid in the mouth or oral cavity of the human or animal, preferably the human or animal in need thereof. The inventive embodiments include a method of protecting a surface of a human or animal, preferably a human or animal in need thereof, from contact with a fluid or other substance, the method comprising contacting the surface to be protected with the scented and/or flavoured cotton or cotton product. In different embodiments, the fluid can, for example, be saliva, blood, and /or water, the other substance can be, for example, a dental adhesive, a dental sealant, and /or a dental cement, and the surface to be protected can be, for example, the tongue, a cheek, a tooth, a portion of a tooth, a crown surface, a filling surface, a tooth are that includes a hole, a nose, a torso, a nose and a mouth, and/or a gum.
Without limitations, the above methods may be combined; the human, or human in need thereof, may be, for example, a dentist or a patient, or a dental assistant, such as a dental hygienist, or x-ray technician; and the scented and/or flavoured cotton product can be, for example, a cotton roll, a cotton beam, a cotton mask, a cotton bib, a cotton cube a cotton strip, and /or a cotton pellet.
An animal includes, without limitation, a dog, a cat, a horse, a sheep, a cow, a donkey, an ape, a reptile, a lion, a tiger, a liger, a panda, a bear, a gazelle, a cheetah, a leopard, a hyena, a giraffe, a hippo, a beaver, a deer, a goat, an elk, a lama, and a pig. In one
embodiment, an animal is a warm blooded animal. In another embodiment, the animal is a warm blooded animal excluding a human.
Scented and/or flavoured cotton or cotton products will give off scents even when they are dry. When a scented and/or flavoured cotton or cotton product gets wet in the patient's mouth, it will give off stronger flavour. The strength of the flavour can be controlled by the amount of the scent in the solution during the manufacturing process of the scented and/or flavoured cotton or cotton products. Surprisingly, it was found that when unscented cotton rolls are scented by dipping a scented solution or by spraying of the scented solution, the shape of the roll is sometimes changed, sometimes slightly. Without being bound by theory, it is believed that the shape change occurs because of a swelling of the roll when it gets wet. When cotton rolls are made of pre-scented cotton, the cylindrical shape of the roll can be well maintained, just like the conventional unscented cotton roll.
PREFERRED EMBODIMENTS
Without being limiting, the following are preferred inventive embodiments:
1 ) A scented cotton comprising a scent.
2) The scented cotton of embodiment 1 , wherein the scented cotton is in the form of a roll.
3) The scented cotton roll of embodiment 2, wherein the scent is selected from the group consisting of lemon, lime, coffee, peach, jasmine, mint, peppermint, honey, root beer, wintergreen, orange, fruity, rum, coffee, chocolate, cocoa, butter, cream, cherry, apricot, grape, pineapple, pear, strawberry, jasmine, cinnamon, vanilla, almond, apple, marshmallow, banana, strawberry, bubble gum, raspberry, pepper, tea, caramel, and combinations of these scents.
4) The scented cotton roll of embodiment 2, wherein the scent is imparted by a molecule selected from the group consisting of allyl hexanoate, benzyl acetate, ethyl butyrate, ethyl hexanoate, butyl butyrate, ethyl cinnamate, ethyl formate, ethyl heptanoate, ethyl isovalerate, ethyl lactate, ethyl nonanoate, ethyl pentanoate, geranyl butyrate, geranyl pentanoate, 2,5-dimethylpyrazine, isobutyl acetate, methyl phenyl acetate, methyl salicylate, nonyl caprylate, 4-hydroxy-3- methoxy benzaldehyde, benzaldehyde, methyl-2-pyridyl ketone, ethyl-2-methyl butyrate, ethyl-3-hydroxy butanoate, isoamyl acetate, ethyl methylphenylglycidate, prenyl acetate, isobutyl formate, isopropyl acetate, linalyl acetate, linalyl butyrate, linalyl formate, methyl acetate, methyl anthranilate, methyl benzoate methyl benzyl acetate, methyl butyrate, methyl cinnamate, methyl pentanoate, octyl acetate, octyl butyrate, amyl acetate, amyl butyrate, pentyl hexanoate, pentyl pentanoate, propyl ethanoate, propyl isobutyrate, terpenyl butyrate and combinations thereof.
5) The scented cotton roll of embodiment 4, wherein the amount of each molecule comprised therein ranges from 100 μg to 100 mg.
6) The scented cotton roll of embodiment 2, wherein the scented cotton roll comprises thymol, eucalyptol, methyl salicylate, and menthol.
7) The scented cotton roll of embodiment 6, further comprising a sweetner.
8) The scented cotton roll of embodiment 7, wherein the sweetener is selected from sorbitol, sodium saccharine, saccharine, acesulfame potassium, sucralose, erythritol, a hydrogenated starch hydrolysate, isomalt, lactitol, maltitol, mannitol, xylitol, stevia, and combinations thereof.
9) The scented cotton roll of embodiment 8, wherein the sweetener is a combination of sodium saccharine and sorbitol.
10) The scented / flavoured cotton roll of embodiment 2, wherein the scented cotton roll is coloured.
1 1 ) The scented cotton roll of embodiment 10, wherein the colour is selected from the group consisting of red, orange, yellow, green, blue, cyan, indigo, violet, white, brown, black, and combinations thereof. 12) The scented cotton roll of embodiment 10, wherein the scented cotton roll comprises a colouring selected from FD&C Blue No. 1 , FD&C Blue No. 2, FD&C Green No. 3, FD&C Red No. 40, FD&C Red No. 3, FD&C Yellow No. 5, FD&C Yellow No. 6, and combinations thereof.
1 3) The scented cotton roll of embodiment 12, wherein the scented cotton roll comprises FD&C Green No. 3.
14) The scented cotton roll of embodiment 13, further comprising a surfactant.
15) The scented cotton roll of embodiment 14, where in the surfactant is a
polyoxamer.
16) The scented cotton roll of embodiment 15, wherein the polyoxamer is poloxamer
407.
1 7) The scented cotton roll of embodiment 16, further comprising a preservative.
1 8) The scented cotton roll of embodiment 17, wherein the preservative comprises sodium benzoate.
19) A method of protecting a surface in the mouth of a subject in need thereof, the method comprising, contacting the surface with the scented cotton roll of embodiment 2, thereby protecting the surface of the subject in need thereof.
20) A method of absorbing a fluid in the mouth of a subject in need thereof, the method comprising, absorbing the fluid from the mouth of the subject in need thereof with the scented cotton roll of embodiment 2.
21 ) A method of making the scented cotton roll of embodiment 2, the method comprising contacting a cotton roll with a scent to form the scented cotton roll. 22) A method of conducting a dental procedure, the method comprising conducting the dental procedure with the scented cotton roll of embodiment 2.
23) The scented cotton of embodiment 1 , further comprising a taste.
24) The scented cotton of embodiment 23, wherein the taste is selected from sweet, sour, bitter, salty, savory, and combinations thereof.
25) A method of attenuating and/or partially attenuating and/or masking and/or partially masking an undesired smell created during a dental procedure, for a person or animal in need thereof, the method comprising conducting the dental procedure with the scented cotton roll of embodiment 2, thereby attenuating and/or partially attenuating and/or masking and/or partially masking the undesired smell in the person or animal in need thereof.
26) The method of embodiment 25, wherein the undesired smell is created by the operation of a dental drill on a tooth.
27) A method of masking or partially masking an undesired smell created during a dental procedure for a person or animal in need thereof, the method comprising conducting the dental procedure with the scented cotton roll of embodiment 2, thereby masking or partially masking the undesired smell for the person in need thereof.
28) A method of conducting a dental procedure, the method comprising conducting the dental procedure with the scented cotton of embodiment 1 or the flavoured cotton of embodiment 31 .
29) A method of protecting a surface in the mouth of a subject in need thereof, the method comprising, contacting the surface with the scented cotton of embodiment 1 or the flavoured cotton of embodiment 3 1 , thereby protecting the surface in the mouth of the subject in need thereof. 30) A method of making the scented cotton of embodiment 1 , the method comprising contacting a cotton with a scent to form the scented cotton.
31 ) A flavoured cotton comprising a taste ingredient.
32) A method of making the flavoured cotton of embodiment 31 , the method comprising contacting a cotton with a taste ingredient to form the flavoured cotton.
EXAMPLES
The present invention is described by way of example in the examples hereinafter. Obviously, numerous modifications and variations of the present invention are possible in light of the above teachings. It is therefore to be understood that, within the scope of the appended claims, the invention may be practiced otherwise than as specifically described herein.
Example 1 : Preparation of a colored, sweetened, and scented / flavoured cotton roll
Cylindrical cotton rolls (Manufacturer Pearson Cotton Rolls- Mfg Part # 96-9125) in a standard size of 1 1 /2" x 3/8" were dipped / immersed into a solution comprising: thymol (0.064% by weight, based on the weight of the solution), eucalyptol (0.092% by weight, based on the weight of the solution), methyl salicylate (0.060% by weight, based on the weight of the solution), menthol (0.042% by weight, based on the weight of the solution, alcohol (21 .6%) by weight, based on the weight of the solution), with the remaining ingredients, being water, sorbitol, flavoring, poloxamer 407, benzoic acid, sodium saccharin, sodium benzoate, and FD&C Green 3 (e.g., Listerine Cool Mint). The dipped / immersed cotton rolls were air dried at room temperature, to produce the coloured, sweetened and scented/flavoured cotton rolls.
Example 2: Human Preference Test
Three human adults were presented with a coloured, sweetened and scented/flavoured cotton roll from Example 1 , supra. The human adults were previously exposed to a standard white cotton roll. The human adults examined and sniffed the coloured, sweetened and scented/flavoured cotton roll. All three humans indicated a preference for the coloured, scented/flavoured, sweetened cotton roll as compared to the standard white cotton roll.
The above written description of the invention provides a manner and process of making and using it such that any person skilled in this art is enabled to make and use the same, this enablement being provided in particular for the subject matter of the appended claims, which make up a part of the original description of the invention.
As used above, the phrases "selected from the group consisting of," "chosen from," and the like include mixtures of specified materials.
All references, patents, applications, tests, standards, documents, publications, brochures, texts, labels, articles, etc. mentioned herein are incorporated herein by reference. Where a numerical range or limit is stated, the endpoints are included. Also, all values and subranges within a numerical limit or range are specifically included as if explicitly written out. Terms such as "contain(s)" and the like as used herein are open terms meaning
'including at least' unless otherwise specifically noted. The terms "a" and "an" mean one or more, unless otherwise specifically noted. The above description is presented to enable a person skilled in the art to make and use the invention, and is provided in the context of a particular application and its
requirements. Various modifications to the preferred embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments and applications without departing from the spirit and scope of the invention. Thus, this invention is not intended to be limited to the embodiments shown, but is to be accorded the widest scope consistent with the principles and features disclosed herein.

Claims

1 ) A scented cotton comprising a scent.
2) The scented cotton of claim 1 , wherein the scented cotton is in the form of a roll.
3) The scented cotton roll of claim 2, wherein the scent is selected from the group consisting of lemon, lime, coffee, peach, jasmine, mint, peppermint, honey, root beer, wintergreen, orange, fruity, rum, coffee, chocolate, cocoa, butter, cream, cherry, apricot, grape, pineapple, pear, strawberry, jasmine, cinnamon, vanilla, almond, apple, marshmallow, banana, strawberry, bubble gum, raspberry, pepper, tea, caramel, and combinations of these scents.
4) The scented cotton roll of claim 2, wherein the scent is imparted by a molecule selected from the group consisting of allyl hexanoate, benzyl acetate, ethyl butyrate, ethyl hexanoate, butyl butyrate, ethyl cinnamate, ethyl formate, ethyl heptanoate, ethyl isovalerate, ethyl lactate, ethyl nonanoate, ethyl pentanoate, geranyl butyrate, geranyl pentanoate, 2,5- dimethylpyrazine, isobutyl acetate, methyl phenyl acetate, methyl salicylate, nonyl caprylate, 4-hydroxy-3- methoxy benzaldehyde, benzaldehyde, methyl-2-pyridyl ketone, ethyl -2-methyl butyrate, ethyl-3-hydroxy butanoate, isoamyl acetate, ethyl methylphenylglycidate, prenyl acetate, isobutyl formate, isopropyl acetate, linalyl acetate, linalyl butyrate, linalyl formate, methyl acetate, methyl anthranilate, methyl benzoate methyl benzyl acetate, methyl butyrate, methyl cinnamate, methyl pentanoate, octyl acetate, octyl butyrate, amyl acetate, amyl butyrate, pentyl hexanoate, pentyl pentanoate, propyl ethanoate, propyl isobutyrate, terpenyl butyrate and combinations thereof.
5) The scented cotton roll of claim 4, wherein the amount of each molecule comprised therein ranges from 100 μg to 100 mg.
6) The scented cotton roll of claim 2, wherein the scented cotton roll comprises thymol, eucalyptol, methyl salicylate, and menthol.
7) The scented cotton roll of claim 6, further comprising a sweetner.
8) The scented cotton roll of claim 7, wherein the sweetener is selected from sorbitol, sodium saccharine, saccharine, acesulfame potassium, sucralose, erythritol, a hydrogenated starch hydrolysate, isomalt, lactitol, maltitol, mannitol, xylitol, stevia, and combinations thereof.
9) The scented cotton roll of claim 8, wherein the sweetener is a combination of sodium saccharine and sorbitol.
1 0) The scented / flavoured cotton roll of claim 2, wherein the scented cotton roll is coloured. 1 1 ) The scented cotton roll of claim 10, wherein the colour is selected from the group consisting of red, orange, yellow, green, blue, cyan, indigo, violet, white, brown, black, and combinations thereof.
12) The scented cotton roll of claim 10, wherein the scented cotton roll comprises a colouring selected from FD&C Blue No. 1 , FD&C Blue No. 2, FD&C Green No. 3, FD&C Red No. 40, FD&C Red No. 3, FD&C Yellow No. 5, FD&C Yellow No. 6, and combinations thereof.
13) The scented cotton roll of claim 12, wherein the scented cotton roll comprises FD&C Green No. 3.
14) The scented cotton roll of claim 13, further comprising a surfactant.
15) The scented cotton roll of claim 14, where in the surfactant is a polyoxamer.
16) The scented cotton roll of claim 15, wherein the polyoxamer is poloxamer 407.
1 7) The scented cotton roll of claim 16, further comprising a preservative.
18) The scented cotton roll of claim 17, wherein the preservative comprises sodium benzoate. 19) A method of protecting a surface in the mouth of a subject in need thereof, the method comprising, contacting the surface with the scented cotton roll of claim 2, thereby protecting the surface of the subject in need thereof.
20) A method of absorbing a fluid in the mouth of a subject in need thereof, the method comprising, absorbing the fluid from the mouth of the subject in need thereof with the scented cotton roll of claim 2.
21 ) A flavoured cotton comprising a taste ingredient.
PCT/US2009/058610 2009-09-28 2009-09-28 Scented and/or flavoured cotton and products therefrom WO2011037589A1 (en)

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EP3988536A1 (en) * 2020-10-26 2022-04-27 Zhejiang Enmat Biological Technology Co., Ltd. Efficient anti-bacterial hydroxy acid ester oligomer

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