WO2011031999A3 - Multi-component nanoparticle structure having detectable magnetic resonance properties - Google Patents
Multi-component nanoparticle structure having detectable magnetic resonance properties Download PDFInfo
- Publication number
- WO2011031999A3 WO2011031999A3 PCT/US2010/048468 US2010048468W WO2011031999A3 WO 2011031999 A3 WO2011031999 A3 WO 2011031999A3 US 2010048468 W US2010048468 W US 2010048468W WO 2011031999 A3 WO2011031999 A3 WO 2011031999A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- magnetic resonance
- nanoparticle structure
- segments
- resonance properties
- detectable magnetic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
- A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
- A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
- A61K49/1827—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/12—Macromolecular compounds
- A61K49/126—Linear polymers, e.g. dextran, inulin, PEG
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Nanotechnology (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Radiology & Medical Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
A nanoparticle structure includes a sequence of segments. In particular, the structure includes a first plurality of segments comprising gold-coated DNA, and a second plurality of segments comprising DNA coated with a paramagnetic material. The first plurality of segments are interleaved with the second plurality of segments. The mass ratio of the combined mass of gold and paramagnetic material to a mass of DNA material is less than 5: 1.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24121609P | 2009-09-10 | 2009-09-10 | |
US61/241,216 | 2009-09-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2011031999A2 WO2011031999A2 (en) | 2011-03-17 |
WO2011031999A3 true WO2011031999A3 (en) | 2011-08-04 |
Family
ID=43733112
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2010/048468 WO2011031999A2 (en) | 2009-09-10 | 2010-09-10 | Multi-component nanoparticle structure having detectable magnetic resonance properties |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2011031999A2 (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020098135A1 (en) * | 1997-03-07 | 2002-07-25 | William Marsh Rice University | Array of single-wall carbon nanotubes |
US20020177143A1 (en) * | 2001-05-25 | 2002-11-28 | Mirkin Chad A. | Non-alloying core shell nanoparticles |
US20060079455A1 (en) * | 2003-01-07 | 2006-04-13 | Ramot At Tel Aviv University Ltd. | Peptide nanostructures encapsulating a foreign material and method of manufacturing same |
-
2010
- 2010-09-10 WO PCT/US2010/048468 patent/WO2011031999A2/en active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020098135A1 (en) * | 1997-03-07 | 2002-07-25 | William Marsh Rice University | Array of single-wall carbon nanotubes |
US20020177143A1 (en) * | 2001-05-25 | 2002-11-28 | Mirkin Chad A. | Non-alloying core shell nanoparticles |
US20060079455A1 (en) * | 2003-01-07 | 2006-04-13 | Ramot At Tel Aviv University Ltd. | Peptide nanostructures encapsulating a foreign material and method of manufacturing same |
Also Published As
Publication number | Publication date |
---|---|
WO2011031999A2 (en) | 2011-03-17 |
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