WO2011027311A3 - Novel tumor markers - Google Patents

Novel tumor markers Download PDF

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Publication number
WO2011027311A3
WO2011027311A3 PCT/IB2010/053943 IB2010053943W WO2011027311A3 WO 2011027311 A3 WO2011027311 A3 WO 2011027311A3 IB 2010053943 W IB2010053943 W IB 2010053943W WO 2011027311 A3 WO2011027311 A3 WO 2011027311A3
Authority
WO
WIPO (PCT)
Prior art keywords
stage
progressed
tumor markers
cancer
expression
Prior art date
Application number
PCT/IB2010/053943
Other languages
French (fr)
Other versions
WO2011027311A2 (en
Inventor
Ralf Hoffmann
Edwin P. Romijn
Hugo M. Visser
Tim Hulsen
Original Assignee
Koninklijke Philips Electronics N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips Electronics N.V. filed Critical Koninklijke Philips Electronics N.V.
Publication of WO2011027311A2 publication Critical patent/WO2011027311A2/en
Publication of WO2011027311A3 publication Critical patent/WO2011027311A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57434—Specifically defined cancers of prostate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention relates to a tumor marker or group of tumor markers associated with the progression of a cancer disease from a less progressed stage to a more progressed stage, wherein the expression of the tumor markers is modified when comparing the expression in the less progressed stage and in the more progressed stage. The present invention further relates to a composition for diagnosing, detecting, graduating, monitoring or prognosticating a cancer disease associated with a progression from a less progressed cancer stage to a more progressed cancer stage comprising affinity ligands for the expression products of the tumor markers, to corresponding methods, and to the use of said tumor markers for detecting, diagnosing, graduating, monitoring or prognosticating a cancer disease associated with a progression from a less progressed cancer stage to a more progressed cancer stage. The present invention further relates to a corresponding immunoassay, to a method of identifying an individual for eligibility for a cancer disease therapy, as well as to a pharmaceutical composition based on the inhibition and/or activation of the expression of said tumor markers.
PCT/IB2010/053943 2009-09-03 2010-09-02 Novel tumor markers WO2011027311A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP09169423 2009-09-03
EP09169427 2009-09-03
EP09169423.2 2009-09-03
EP09169427.3 2009-09-03

Publications (2)

Publication Number Publication Date
WO2011027311A2 WO2011027311A2 (en) 2011-03-10
WO2011027311A3 true WO2011027311A3 (en) 2011-05-12

Family

ID=43383461

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2010/053943 WO2011027311A2 (en) 2009-09-03 2010-09-02 Novel tumor markers

Country Status (1)

Country Link
WO (1) WO2011027311A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201110938D0 (en) * 2011-06-27 2011-08-10 Iti Scotland Ltd Compounds
JP2014526682A (en) 2011-09-12 2014-10-06 クリエイティクス エルエルシー Non-invasive method for detecting target molecules
WO2014160499A2 (en) * 2013-03-13 2014-10-02 Creatics Llc Methods and compositions for detecting pancreatic cancer
GB201521746D0 (en) * 2015-12-10 2016-01-27 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against CLL and other cancers
CN110885805B (en) * 2018-09-07 2021-09-07 广东凯安生命技术有限公司 Polypeptide with immune cell targeting recognition function and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002090580A1 (en) * 2001-05-03 2002-11-14 National Cancer Centre Of Singapore Pte Ltd Identifying liver cancer by detecting aberrant expression of insulin like growth factor binding protein
WO2007034221A2 (en) * 2005-09-23 2007-03-29 University Court Of The University Of Aberdeen Non small cell lung cancer therapy prognosis and target
WO2009055823A2 (en) * 2007-10-26 2009-04-30 Progen Pharmaceuticals Limited Method to predict responsiveness of breast cancer to polyaminetype chemotherapy

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002090580A1 (en) * 2001-05-03 2002-11-14 National Cancer Centre Of Singapore Pte Ltd Identifying liver cancer by detecting aberrant expression of insulin like growth factor binding protein
WO2007034221A2 (en) * 2005-09-23 2007-03-29 University Court Of The University Of Aberdeen Non small cell lung cancer therapy prognosis and target
WO2009055823A2 (en) * 2007-10-26 2009-04-30 Progen Pharmaceuticals Limited Method to predict responsiveness of breast cancer to polyaminetype chemotherapy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TOBIAS SJ¦BLOM ET AL: "The Consensus Coding Sequences of Human Breast and Colorectal Cancers", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, WASHINGTON, DC; US, vol. 314, 13 October 2006 (2006-10-13), pages 268 - 274, XP007901261, ISSN: 0036-8075, DOI: DOI:10.1126/SCIENCE.1133427 *

Also Published As

Publication number Publication date
WO2011027311A2 (en) 2011-03-10

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