Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
  • A61B5/00—Measuring for diagnostic purposes; Identification of persons
  • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
  • A61B5/053—Measuring electrical impedance or conductance of a portion of the body
  • A61B5/0531—Measuring skin impedance
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
  • A61B5/00—Measuring for diagnostic purposes; Identification of persons
  • A61B5/16—Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
  • A61B5/00—Measuring for diagnostic purposes; Identification of persons
  • A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
  • A61B5/00—Measuring for diagnostic purposes; Identification of persons
  • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
  • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
  • A61B5/6813—Specially adapted to be attached to a specific body part
  • A61B5/6825—Hand
  • A61B5/6826—Finger

Definitions

• This invention relates to the field of medicine and medical devices, namely to a method and apparatus for diagnostics of the individual's organism state by measuring skin potential response (SPR).
• SPR skin potential response
• first type transition are characterized by sudden and unintentional flow, when individual unconsciously makes transitions from one psychophysiological state to another in a short term (less than 5 minutes), and second type transitions characterizing by gradual development when the changes of PPS are accumulated in the course of activity in a long term (30 minutes and more).
• second type transitions characterizing by gradual development when the changes of PPS are accumulated in the course of activity in a long term (30 minutes and more).
• 4,088,125 includes electrodes for sensing the skin potential, an amplifier for amplifying the signal and feeding the signal into a pair of variable comparators which provide output when the response exceeds preset upper and lower limits.
• the outputs provide a feedback signal either audio or visual, or to serve as inputs to auxiliary instrumentation. No feedback signal is produced as long as the monitored signal is within the selected limits.
• the magnitude of the responses may be quantified to the extent that they exceed the preset levels.
• the apparatus described in ' 125 requires preliminary measuring of the limits for different individuals in different PFSs. In a method and an apparatus for registration skin potential response described in
• a mobile apparatus for individual state monitoring taught in published U.S. Pat. Application No. 2008/00214903 have means of real-time data collection from one or more sensors placed on the body of individual and means of presenting aforementioned data on mobile device display (phone, notebook, etc.) for self control.
• mobile device display phone, notebook, etc.
• PPS PPS is estimated not by apparatus, but by individual himself based on apparatus measurements the apparatus described in '903 is unsuitable for real-time PPS estimation. This apparatus only informs individual about the sensors measurements.
• An apparatus described in '460 comprising electrodes, having means of fixation, which are connected to input unit, means of pulse interference blanking, means of signal extraction from phase component band of electrodermal activity, means of detecting phase component impulses and registration unit, wherein means of signal extraction from phase component band of electrodermal activity, means of detecting phase component impulses implemented as daisy chain to lower frequencies input filter of the incoming signal to first and second time derivative transformation unit and impulse shape analysis unit, wherein the exit of the latter is connected to the input of the registration unit.
• An apparatus described in '460 can not be utilized by individuals having high skin conductivity, as measuring of electric current with constant voltage requires proportional increase in electric current as skin resistance growths. This may influence to the skin metabolic processes leading to the result distortion.
• This apparatus is also requires an etalon samples of individual reactions to be predetermined.
• the signal processing includes the first and the second derivative calculation of the current value logarithm by using of rather complex arrangement, comprising memory unit and impulse shape analysis unit.
• an apparatus for registration of transitions between psychophysiological states of individual comprising
• a reading unit arranged to be capable of measuring an electromotive force under direct electric current of 0.5 to 5.0 microampere to produce a signal
• a quantization unit arranged to be capable of quantization of signal by level, said quantization unit comprising
• a comparator arranged to be capable of determining of whether the difference between the current and the previous signal value is greater than N, where N is a predefined value from 0.1 to 2.0 centineper;
• a pulse generator arranged to be capable of generating a pulse having an amplitude of N when the difference between the current and the previous signal value is greater than N;
• the apparatus further comprising (g) a compensating unit arranged to be capable of correcting the signal value from logarithmic unit by the pulse value from pulse generator to produce corrected signal, and supplying corrected signal to said comparator;
• step (b) logarithming of signal is taken in step (a);
• step (c) quantizing the logarithm of signal from step (b) by level from 0.1 to 2.0 centineper;
• Technical effect of present invention is the increase in informational content of SPR signal, improved reliability of PPS transition registration and simplification of preliminary definition of allowance for individual skin features.
• FIG. 1 is a block diagram of the particular embodiment according to present invention.
• Fig. 2 is a block diagram of the transition registration method. Beginning (10). Initial values setup (1 1). Measurements (12) by units (1-2). Signal processing (13) in units (3-5). If condition (14): «is there a signal from pulse generator (6)?» is not satisfied, then measurement continue (12), else if condition (15) «does level of signal change with maximal speed 2 seconds?» or condition (16) «does level of signal differ from initial more then 1.5 fold?» satisfied, then the program of reaction to PPS state of subject is used (17), else measurements continue (12).
• the present invention is applicable for registration of said first type and second type transitional states.
• technical effect of present invention is the increase in informational content of SPR signal, improved reliability of PPS transition registration and simplification of preliminary adjusting to individual skin features.
• a reading unit arranged to be capable of measuring an electromotive force under direct electric current of 0.5 to 5.0 microampere to produce a signal
• a quantization unit arranged to be capable of quantization of signal by level, said quantization unit comprising (e) a comparator arranged to be capable of determining of whether the difference between the current and the previous signal value is greater than N, where N is a predefined value from 0.1 to 2.0 centineper; and
• a pulse generator arranged to be capable of generating a pulse having an amplitude of N when the difference between the current and the previous signal value is greater than N;
• the apparatus further comprising
• a compensating unit arranged to be capable of correcting the signal value from logarithmic unit by the pulse value from pulse generator to produce corrected signal, and supplying corrected signal to said comparator;
• the apparatus further comprising (j) a signal transmitting unit, wherein said reading unit have an output and said logarithmic unit have an input connected thereto; said logarithmic unit have an output and said compensating unit have a first input connected thereto; said comparator have an output and said pulse generator have an input connected thereto; said pulse generator have a first output and said signal transmitting unit have an input connected thereto; said pulse generator have a second output and said compensating unit have a second input connected thereto; said transmitting unit have an output and said processing unit have an input connected thereto.
• the apparatus further comprising (k) a control unit having a thermometer, said control unit is capable of controlling a reliability of registration.
• said electrodes is in the form of rings for fingers of one hand, and its body frame is in the form of a crossbar with said rings connected thereto.
• Such an apparatus may be implemented, for instance, as double ring with contacts on the palm sides of the fingers, wherein the crossbar between the rings accommodates power unit, logarithmic amplifier, quantization unit and signal transmission unit (all those implemented as one or several microchips).
• Signal transmission unit may be implemented as galvanic decoupler, which may be implemented as Bluetooth microchip or any other transmitting device, compatible with receiving unit of the processing center. Combination of processing center and detector in one physical unit is also possible.
• the apparatus further comprising glove to put on hand of individual with said electrodes accommodated therein.
• the apparatus further comprising (1) radio transmitter unit and (m) data receiving unit connected to said processing unit, wherein said radio transmitter unit and said receiving unit are connected by wireless communication channel thereby enabling data exchange therebetween.
• the apparatus further comprising (1) radio transmitter unit and (m) data receiving unit connected to said processing unit, wherein said radio transmitter unit and said receiving unit are connected by wireless or wired communication channel thereby enabling data exchange therebetween.
• said processing unit is a mobile communication device, a mobile phone, a cellular phone, a communicator or a smartphone.
• processing unit is an automobile onboard computer.
• processing unit is a computer, a desktop computer, a mobile computer or a pocket computer.
• apparatus further comprising (n) recording means capable of recording the results.
• the apparatus further comprising an (o) executive unit capable of affecting at least one sense organ of individual.
• said executive unit is arranged to be capable of affecting of at least one sense organ of individual by sound, light, vibration and/or odor.
• the apparatus further comprising (o) an executive unit affecting individual's sense organs, accommodated in said processing unit or connected thereto.
• said power supply is connected by a conductor to said processing unit.
• said power supply is accommodated in said processing unit.
• the apparatus further comprising at least one unit arranged to be capable of creating of alternating magnetic field, which is accommodated in said power supply, and at least one unit capable of generating electromotive force induced by said magnetic field.
• the apparatus further comprising at least one unit arranged to be capable of creating of alternating magnetic field and at least two unit capable of generating electromotive force induced by said magnetic field, wherein at least one of those units is accommodated in said transmitting unit and the others is accommodated in said processing unit.
• at least two of said logarithmic unit, said compensating unit, said quantization unit, said transmitting unit, said processing unit, said executive unit and said power supply are accommodated in one body.
• a method for registration of psychophysiological state transition of individual comprising the following steps:
• step (b) logarithming of signal is taken in step (a);
• step (c) quantizing the logarithm of signal from step (b) by level from 0.1 to 2.0 centineper;
• two electrodes are fixed upon individual's body.
• Preferred signal registration zones are skin areas with increased concentration of nerve endings, particularly palm sides of the fingers.
• Minimal flow of direct current is applied to electrodes (1), preferably from 0.5 to 5.0 microampere, especially preferable is 2.0 microampere current.
• Signal (emf) is measured with reading unit (2), with acquisition of continuous analogous signal E.
• logarithmic unit (3) logarithm of signal is taken and transformed into digital form, thereby acquiring reading of signal logarithm:
• corrections Q are brought in signal logarithm at the output of logarithmic unit (3).
• Corrections Q represent accumulated value of signal logarithm on the previous apparatus cycle:
• Transitional state of the first type is registered in case of the high frequency of the unidirectional impulses during two seconds (positive impulses - transition into more active state, negative - into less active). Otherwise, if the signal level changes 1.5-3 fold comparing to initial value in the course of a longer time period, then the transitional state of the second type is registered.
• Certain level of transition is defined through routine experiments, taking into account the individual's specific speed of the signal alteration during excitation or relaxation. Speed of the signal alteration is defined during the experiment.
• signal level in the range from 150 to 600 centineper is achieved (range for the activation state, defined empirically), to do so individual is proposed to do some actions, directed to stable standing in activation state.
• range for the activation state is due to individual skin characteristics of different subjects. As far as this level might vary for the same individual depending on many factors (season and health) tuning is done every time current method or apparatus is applied.
• Advantage of the present method is that tuning for individual parameters if a subject is reduced to simple operations and takes not more then two minutes.
• Signal level quantization allows reduction of noise, due to specialties of the measurements methods, and disturbances due to subject activities. Therefore utilization of the present invention allows to increase the reliability of the operational esteem of the individual psychophysiological state during his activity and makes it possible to register PPS dangerous for individual.
• the present invention may be used for control or self-control of the
• apparatus has two electrodes (1), electrodes are connected to first and second input of the reading unit (2).
• Output of the reading unit (2) output of the reading unit is connected to input of logarithmic unit (3), output of logarithmic unit is connected to first input of compensating unit (4), output of compensating unit is connected to the input comparator(5), which is a constitutive part of the of the quantization unit together with pulse generator( ⁇ ).
• Output of comparator (5) is connected to input of pulse generator (6).
• First output of pulse generator (6) is connected to second input of compensating unit (4), second output of pulse generator is connected to input of signal transmitting unit (7).
• Output of transmitting unit (7) is connected to input of processing unit (8).
• processing unit (8) is implemented as constructively separated, connected to the rest of the apparatus by communication channel (wired or wireless), or might be implemented in one body with the rest of apparatus.
• output of the processing unit (8) is connected to input of execution unit.
• Apparatus works as follows: reading unit (2) providing the direct current flow in the range from 0.5 to 5 microampere through the electrodes fixed upon the subject skin (1), measures the ems and gives the signal to the input of the logarithmic unit (3).
• Logarithmic unit (3) gives the signal logarithm to the input of compensating unit (4).
• Compensating unit (4) alters the input signal by the current value of the correction Q and gives the signal to the input of comparator (5).
• Comparator (5) compares the current signal to its previous value and if the difference exceeds the preliminary set signal quantization level N (preferably chosen from the range from 0.1 to 2 centineper), then it gives the signal to the input of the pulse generator (6).
• N preferably chosen from the range from 0.1 to 2 centineper
• Transmitting unit (7) transmits the signal to the processing unit (8), preferably by means of radio channel.
• Impulses are transmitted to the processing unit with preferable period from 1 to 1000 msec, especially preferable is the period of 100 msec.
• the transmitting unit (8) gives the signal to execution unit (9). At that execution unit (9) affect the sensual organs of individual.
• the processing unit may contain a program of signal processing and result registration on the storing device, as well as means of synchronization of affect on the subjects and measurements registration.
• apparatus is connected to individual, positive impulses are successively accumulated and averaged to reach the constant average value.
• Time to set the initial signal value according to calculations and experience in signal measurements is preferably from one to two minutes.
• one may use the direct transmission of the first acquired value for the signal logarithm to the processing center, followed by correction by acquired impulses.
• time of initial set up may be shortened to 10 seconds.
• apparatus additionally contains control unit, equipped with temperature meter (body temperature influences the characteristics of skin conduction). Temperature is acquired every two minutes with discretization of 0.1 degree and error +/- 0.2 degrees in the range of temperatures measured (from 10 to 42 degrees).
• Apparatus is characterized by high quality of diagnostics for the transitional states of individual without long time procedure of individual tuning; possibility of subject PPS estimation already after 2 minutes after the measurements started (which provides wide range of possible application for apparatus, from house hold device to operative medical diagnostics); absence of the device influences on the subject distorting the measurements and due to that achievement of high reliability of results; simple scheme of apparatus

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Citations (4)

• 2009
  • 2009-09-29 WO PCT/RU2009/000500 patent/WO2011025404A1/en not_active Ceased
  • 2009-09-29 IN IN2669DEN2012 patent/IN2012DN02669A/en unknown

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