WO2011022542A3 - Administration of factors normally present in a microbial niche to improve health - Google Patents

Administration of factors normally present in a microbial niche to improve health Download PDF

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Publication number
WO2011022542A3
WO2011022542A3 PCT/US2010/045999 US2010045999W WO2011022542A3 WO 2011022542 A3 WO2011022542 A3 WO 2011022542A3 US 2010045999 W US2010045999 W US 2010045999W WO 2011022542 A3 WO2011022542 A3 WO 2011022542A3
Authority
WO
WIPO (PCT)
Prior art keywords
host
administration
normally present
improve health
factors normally
Prior art date
Application number
PCT/US2010/045999
Other languages
French (fr)
Other versions
WO2011022542A2 (en
Inventor
Jonathan Robert Behr
W. Edward Martucci
Bernat Olle
Original Assignee
Puretech Ventures, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Puretech Ventures, Llc filed Critical Puretech Ventures, Llc
Publication of WO2011022542A2 publication Critical patent/WO2011022542A2/en
Publication of WO2011022542A3 publication Critical patent/WO2011022542A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Methods to modulate the microbiota for the improvement of health using host and host-derived factors have been developed. Compositions for the modulation of the microbiota for the improvement of health comprising host and host-derived factors are also described. In particular, methods for identifying or compositions comprising host and host-derived compositions that are present in the healthy host environment and that normally select for or support the growth of beneficial commensal microbes are described.
PCT/US2010/045999 2009-08-19 2010-08-19 Administration of factors normally present in a microbial niche to improve health WO2011022542A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23520709P 2009-08-19 2009-08-19
US61/235,207 2009-08-19

Publications (2)

Publication Number Publication Date
WO2011022542A2 WO2011022542A2 (en) 2011-02-24
WO2011022542A3 true WO2011022542A3 (en) 2011-04-14

Family

ID=43479420

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/045999 WO2011022542A2 (en) 2009-08-19 2010-08-19 Administration of factors normally present in a microbial niche to improve health

Country Status (1)

Country Link
WO (1) WO2011022542A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011151941A1 (en) 2010-06-04 2011-12-08 国立大学法人東京大学 Composition having activity of inducing proliferation or accumulation of regulatory t cell
JP5969619B2 (en) 2011-11-08 2016-08-17 ザ プロクター アンド ギャンブル カンパニー Prebiotic identification method and composition containing the same
EP2785828B1 (en) 2011-12-01 2020-04-08 The University of Tokyo Human-derived bacteria that induce proliferation or accumulation of regulatory t cells
EP2814454A2 (en) * 2012-02-14 2014-12-24 The Procter and Gamble Company Topical use of a skin-commensal prebiotic agent and compositions containing the same
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
EP3904502A3 (en) 2013-02-04 2022-02-23 Seres Therapeutics, Inc. Compositions and methods
EP2951285A4 (en) 2013-02-04 2016-10-26 Seres Therapeutics Inc Compositions and methods for inhibition of pathogenic bacterial growth
WO2014145958A2 (en) 2013-03-15 2014-09-18 Seres Health, Inc. Network-based microbial compositions and methods
MX367109B (en) 2013-11-25 2019-08-05 Seres Therapeutics Inc Synergistic bacterial compositions and methods of production and use thereof.
EP3082431A4 (en) 2013-12-16 2017-11-15 Seres Therapeutics, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders
MA41020A (en) 2014-11-25 2017-10-03 Evelo Biosciences Inc PROBIOTIC AND PREBIOTIC COMPOSITIONS, AND THEIR METHODS OF USE FOR MODULATION OF THE MICROBIOME
EP3250184A1 (en) 2015-01-27 2017-12-06 The Johns Hopkins University Hypotonic hydrogel formulations for enhanced transport of active agents at mucosal surfaces
EP3294308A4 (en) 2015-05-14 2019-03-06 University of Puerto Rico Methods for restoring microbiota of newborns
US11564667B2 (en) 2015-12-28 2023-01-31 New York University Device and method of restoring microbiota of newborns
JP2018177669A (en) * 2017-04-07 2018-11-15 尾池 哲郎 Prebiotic cosmetic product that improves diversity of epidermal microorganisms
JP2020530840A (en) 2017-08-14 2020-10-29 セレス セラピューティクス インコーポレイテッド Compositions and Methods for Treating Cholestasis Diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6368586B1 (en) 1996-01-26 2002-04-09 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers
US20070196890A1 (en) 2003-10-02 2007-08-23 Jelena Vulevic Prebiotic effect analysis

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DE ALMEIDA PATRICIA DEL VIGNA ET AL: "Saliva composition and functions: a comprehensive review", THE JOURNAL OF CONTEMPORARY DENTAL PRACTICE, vol. 9, no. 3, 1 March 2008 (2008-03-01), pages 1 - 10, XP002619440 *
MACKAY B J ET AL: "Growth-inhibitory and bactericidal effects of human parotid salivary histidine-rich polypeptides on Streptococcus mutans.", INFECTION AND IMMUNITY, vol. 44, no. 3, June 1984 (1984-06-01), pages 695 - 701, XP002619438, ISSN: 0019-9567 *
MACKAY B J ET AL: "Isolation of milligram quantities of a group of histidine-rich polypeptides from human parotid saliva.", INFECTION AND IMMUNITY, vol. 44, no. 3, June 1984 (1984-06-01), pages 688 - 694, XP002619437, ISSN: 0019-9567 *
POLLOCK J J ET AL: "Fungistatic and Fungicidal Activity of Human Parotid Salivary Histidine-Rich Polypeptides on Candida albicans", INFECTION AND IMMUNITY, vol. 44, no. 3, 1 June 1984 (1984-06-01), AMERICAN SOCIETY FOR MICROBIOLOGY, WASHINGTON, US, pages 702 - 707, XP002482895, ISSN: 0019-9567 *
TSAI H ET AL: "Human salivary histatins: promising anti-fungal therapeutic agents.", CRITICAL REVIEWS IN ORAL BIOLOGY AND MEDICINE : AN OFFICIAL PUBLICATION OF THE AMERICAN ASSOCIATION OF ORAL BIOLOGISTS, vol. 9, no. 4, 1998, pages 480 - 497, XP002619439, ISSN: 1045-4411 *
XU T ET AL: "Anticandidal activity of major human salivary histatins", INFECTION AND IMMUNITY, vol. 59, no. 8, 1 August 1991 (1991-08-01), AMERICAN SOCIETY FOR MICROBIOLOGY, WASHINGTON, US, pages 2549 - 2554, XP002532734, ISSN: 0019-9567 *

Also Published As

Publication number Publication date
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