WO2011013909A3 - Composition containing oligo-hyaluronic acid for promoting the stemness of skin cells and for stimulating differentiation - Google Patents

Composition containing oligo-hyaluronic acid for promoting the stemness of skin cells and for stimulating differentiation Download PDF

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Publication number
WO2011013909A3
WO2011013909A3 PCT/KR2010/004185 KR2010004185W WO2011013909A3 WO 2011013909 A3 WO2011013909 A3 WO 2011013909A3 KR 2010004185 W KR2010004185 W KR 2010004185W WO 2011013909 A3 WO2011013909 A3 WO 2011013909A3
Authority
WO
WIPO (PCT)
Prior art keywords
hyaluronic acid
stemness
promoting
composition containing
cells
Prior art date
Application number
PCT/KR2010/004185
Other languages
French (fr)
Korean (ko)
Other versions
WO2011013909A9 (en
WO2011013909A2 (en
Inventor
김기호
김기수
김영희
김진국
박선희
최혜령
Original Assignee
주식회사 바이오랜드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 바이오랜드 filed Critical 주식회사 바이오랜드
Publication of WO2011013909A2 publication Critical patent/WO2011013909A2/en
Publication of WO2011013909A9 publication Critical patent/WO2011013909A9/en
Publication of WO2011013909A3 publication Critical patent/WO2011013909A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Abstract

The present invention relates to a composition containing oligo-hyaluronic acid for promoting the stemness of skin cells and for stimulating differentiation, and more specifically, to a composition containing oligo-hyaluronic acid as an active ingredient for promoting the stemness of skin cells and for stimulating differentiation, and to a method for stimulating the differentiation of adult skin stem cells using same. According to the present invention, unlike existing hyaluronic acid, oligo-hyaluronic acid exhibits the effects of stimulating differentiation in epidermal cells and enhancing the function of epidermal cells by increasing the expression of markers of the epidermal stem cells in skin tissue to restore the stemness of the epidermal cells.
PCT/KR2010/004185 2009-07-29 2010-06-28 Composition containing oligo-hyaluronic acid for promoting the stemness of skin cells and for stimulating differentiation WO2011013909A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2009-0069624 2009-07-29
KR1020090069624A KR101145394B1 (en) 2009-07-29 2009-07-29 Compositions for promoting stemness and proliferation of skin cells comprising Oligo-hyaluronic acid

Publications (3)

Publication Number Publication Date
WO2011013909A2 WO2011013909A2 (en) 2011-02-03
WO2011013909A9 WO2011013909A9 (en) 2011-05-12
WO2011013909A3 true WO2011013909A3 (en) 2011-06-30

Family

ID=43529802

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/004185 WO2011013909A2 (en) 2009-07-29 2010-06-28 Composition containing oligo-hyaluronic acid for promoting the stemness of skin cells and for stimulating differentiation

Country Status (2)

Country Link
KR (1) KR101145394B1 (en)
WO (1) WO2011013909A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101699354B1 (en) * 2015-04-29 2017-01-24 (주)에스테위즈 Composition, method and kit for regulating differentiation of skin adult stem cell
KR101917026B1 (en) * 2017-03-24 2019-01-24 박원진 Cosmetic composition for skin wrinkle improvement and prevention
KR102540981B1 (en) * 2017-06-30 2023-06-08 (주)아모레퍼시픽 Producing method of artificial skin and artificial skin
WO2019245074A1 (en) * 2018-06-20 2019-12-26 주식회사 디오스템스 Composition having functions of improving survival rate and differentiation rate of stem cells

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070122315A (en) * 2006-06-26 2007-12-31 (주) 에스바이오메딕스 Soft tissue filler composition comprising autologous dermal cell and hyaluronic acid
KR20080062092A (en) * 2006-12-29 2008-07-03 주식회사 핸슨바이오텍 Hyaluronic acid derivatives for cell delivery carriers and their process for preparing the same
KR20080087941A (en) * 2007-03-28 2008-10-02 주식회사 바이오랜드 A composition containing the low molecular weight hyaluronic acid for improving skin wrinkles and skin peeling
KR20090049898A (en) * 2007-11-14 2009-05-19 (주)아모레퍼시픽 3,4,5-trimethoxybenzamide derivatives for increasing the biosynthesis of hyaluronic acid in skin, the method for preparing thereof and cosmetic composition containing the same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100760989B1 (en) 2006-02-15 2007-10-04 주식회사 엠씨티티 Method for Coculturing Fibroblasts and Keratinocytes in Biocompatible Scaffolds

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070122315A (en) * 2006-06-26 2007-12-31 (주) 에스바이오메딕스 Soft tissue filler composition comprising autologous dermal cell and hyaluronic acid
KR20080062092A (en) * 2006-12-29 2008-07-03 주식회사 핸슨바이오텍 Hyaluronic acid derivatives for cell delivery carriers and their process for preparing the same
KR20080087941A (en) * 2007-03-28 2008-10-02 주식회사 바이오랜드 A composition containing the low molecular weight hyaluronic acid for improving skin wrinkles and skin peeling
KR20090049898A (en) * 2007-11-14 2009-05-19 (주)아모레퍼시픽 3,4,5-trimethoxybenzamide derivatives for increasing the biosynthesis of hyaluronic acid in skin, the method for preparing thereof and cosmetic composition containing the same

Also Published As

Publication number Publication date
KR20110012075A (en) 2011-02-09
KR101145394B1 (en) 2012-05-15
WO2011013909A9 (en) 2011-05-12
WO2011013909A2 (en) 2011-02-03

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