WO2011007327A3 - Suspension for therapeutic use and device for delivering said suspension - Google Patents

Suspension for therapeutic use and device for delivering said suspension Download PDF

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Publication number
WO2011007327A3
WO2011007327A3 PCT/IB2010/053229 IB2010053229W WO2011007327A3 WO 2011007327 A3 WO2011007327 A3 WO 2011007327A3 IB 2010053229 W IB2010053229 W IB 2010053229W WO 2011007327 A3 WO2011007327 A3 WO 2011007327A3
Authority
WO
WIPO (PCT)
Prior art keywords
suspension
delivery device
drug delivery
therapeutic use
delivering
Prior art date
Application number
PCT/IB2010/053229
Other languages
French (fr)
Other versions
WO2011007327A2 (en
Inventor
Michel Paul Barbara Van Bruggen
Antonius Wilhelmus Maria De Laat
Original Assignee
Koninklijke Philips Electronics N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips Electronics N.V. filed Critical Koninklijke Philips Electronics N.V.
Publication of WO2011007327A2 publication Critical patent/WO2011007327A2/en
Publication of WO2011007327A3 publication Critical patent/WO2011007327A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention provides a suspension for therapeutic use comprising a fluid dispersion medium, particles that are dispersed in the fluid dispersion medium, and a gelling agent, wherein the particles comprise an amorphous and chemically inert matrix in which a drug is dispersed, and wherein the gelling agent is present in an amount in the range of from 0.01-10 % by weight, based on total suspension. Further, a drug delivery device is provided which comprises a reservoir comprising the suspension and a means for releasing a discrete amount of the suspension from the drug delivery device. In addition, the invention relates to a method for preparing the suspension and the use of the suspension and the drug delivery device for the treatment and/or prevention of a disease.
PCT/IB2010/053229 2009-07-16 2010-07-15 Suspension for therapeutic use and device for delivering said suspension WO2011007327A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09165668 2009-07-16
EP09165668.6 2009-07-16

Publications (2)

Publication Number Publication Date
WO2011007327A2 WO2011007327A2 (en) 2011-01-20
WO2011007327A3 true WO2011007327A3 (en) 2011-12-29

Family

ID=42633336

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2010/053229 WO2011007327A2 (en) 2009-07-16 2010-07-15 Suspension for therapeutic use and device for delivering said suspension

Country Status (1)

Country Link
WO (1) WO2011007327A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9072668B2 (en) 2010-03-09 2015-07-07 Janssen Biotech, Inc. Non-aqueous high concentration reduced viscosity suspension formulations of antibodies

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002032402A1 (en) * 2000-10-13 2002-04-25 Cambridge Biostability Ltd. Composition and method for stable injectable liquids
US6669963B1 (en) * 1997-03-18 2003-12-30 Elan Drug Delivery Limited Stable particle in liquid formulations
WO2006083799A2 (en) * 2005-02-03 2006-08-10 Alza Corporation Suspending vehicles comprising a hydrophilic solvent, a hydrophobic solvent, a polymer and the suitable pump-driven dosage form
US20060251618A1 (en) * 2005-02-03 2006-11-09 Paula Dennis Implantable device for continuous delivery of interferon

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005232441B2 (en) 2004-04-13 2010-11-11 Cambridge Biostability Limited Liquids containing suspended glass particles
US20050266087A1 (en) 2004-05-25 2005-12-01 Gunjan Junnarkar Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6669963B1 (en) * 1997-03-18 2003-12-30 Elan Drug Delivery Limited Stable particle in liquid formulations
WO2002032402A1 (en) * 2000-10-13 2002-04-25 Cambridge Biostability Ltd. Composition and method for stable injectable liquids
WO2006083799A2 (en) * 2005-02-03 2006-08-10 Alza Corporation Suspending vehicles comprising a hydrophilic solvent, a hydrophobic solvent, a polymer and the suitable pump-driven dosage form
US20060251618A1 (en) * 2005-02-03 2006-11-09 Paula Dennis Implantable device for continuous delivery of interferon

Also Published As

Publication number Publication date
WO2011007327A2 (en) 2011-01-20

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