WO2011003623A3 - Method and marker for the individual prognosis and/or the individual detection of neuropathy - Google Patents

Method and marker for the individual prognosis and/or the individual detection of neuropathy Download PDF

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Publication number
WO2011003623A3
WO2011003623A3 PCT/EP2010/004197 EP2010004197W WO2011003623A3 WO 2011003623 A3 WO2011003623 A3 WO 2011003623A3 EP 2010004197 W EP2010004197 W EP 2010004197W WO 2011003623 A3 WO2011003623 A3 WO 2011003623A3
Authority
WO
WIPO (PCT)
Prior art keywords
individual
neuropathy
marker
prognosis
detection
Prior art date
Application number
PCT/EP2010/004197
Other languages
German (de)
French (fr)
Other versions
WO2011003623A2 (en
Inventor
Michael Sereda
Robert Fledrich
Moritz Rossner
Sven Wichert
Klaus Armin Nave
Original Assignee
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE200910032418 external-priority patent/DE102009032418A1/en
Priority claimed from DE200910042090 external-priority patent/DE102009042090A1/en
Application filed by MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. filed Critical MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.
Publication of WO2011003623A2 publication Critical patent/WO2011003623A2/en
Publication of WO2011003623A3 publication Critical patent/WO2011003623A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention relates to a method for the individual prognosis of the occurrence and/or the progression of neuropathy and/or for the individual diagnosis of neuropathy in a mammal, in particular in a human being. It further relates to markers suited for said purpose and to uses of said markers.
PCT/EP2010/004197 2009-07-09 2010-07-09 Method and marker for the individual prognosis and/or the individual detection of neuropathy WO2011003623A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE200910032418 DE102009032418A1 (en) 2009-07-09 2009-07-09 Individual prognosis of occurrence or progression of and/or for individual diagnosis of neuropathy of mammal, comprises detecting expression of mRNA of a gene in a tissue- or fluid sample of mammal, where the gene is e.g. adiponectin
DE102009032418.6 2009-07-09
DE102009042090.8 2009-09-18
DE200910042090 DE102009042090A1 (en) 2009-09-18 2009-09-18 Individual prognosis of occurrence or progression of and/or for individual diagnosis of neuropathy of mammal, comprises detecting expression of mRNA of a gene in a tissue- or fluid sample of mammal, where the gene is e.g. adiponectin

Publications (2)

Publication Number Publication Date
WO2011003623A2 WO2011003623A2 (en) 2011-01-13
WO2011003623A3 true WO2011003623A3 (en) 2011-05-05

Family

ID=42752928

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2010/004197 WO2011003623A2 (en) 2009-07-09 2010-07-09 Method and marker for the individual prognosis and/or the individual detection of neuropathy

Country Status (1)

Country Link
WO (1) WO2011003623A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2540824A1 (en) 2011-06-30 2013-01-02 The Procter & Gamble Company Cleaning compositions comprising amylase variants reference to a sequence listing
EP2551335A1 (en) 2011-07-25 2013-01-30 The Procter & Gamble Company Enzyme stabilized liquid detergent composition
CN105886628B (en) * 2016-04-29 2019-03-26 肖刻 Application of the SPRR1A gene in preparation osteoarthritis diagnostic products
CA3051426C (en) 2017-02-01 2023-10-17 The Procter & Gamble Company Cleaning compositions comprising amylase variants
CN110261619B (en) * 2019-06-14 2021-06-25 上海四核生物科技有限公司 Application of PRKAR2B protein as gastric cancer serum biomarker and kit thereof
EP3986996A1 (en) 2019-06-24 2022-04-27 The Procter & Gamble Company Cleaning compositions comprising amylase variants

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005049866A2 (en) * 2003-11-14 2005-06-02 Duke University Methods of detecting charcot-marie tooth disease type 2a
US20050208544A1 (en) * 2002-07-09 2005-09-22 Broeckhoven Christine V Diagnostic tests for the detection of peripheral neuropathy
US20070059357A1 (en) * 2003-04-28 2007-03-15 Sankyo Company, Limited Adiponectin production enhancer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050208544A1 (en) * 2002-07-09 2005-09-22 Broeckhoven Christine V Diagnostic tests for the detection of peripheral neuropathy
US20070059357A1 (en) * 2003-04-28 2007-03-15 Sankyo Company, Limited Adiponectin production enhancer
WO2005049866A2 (en) * 2003-11-14 2005-06-02 Duke University Methods of detecting charcot-marie tooth disease type 2a

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE ncbi [online] 28 June 2009 (2009-06-28), "Homo sapiens adiponectin and collagen domain containing (ADIPOQ), mRNA", XP002610836, retrieved from ncbi accession no. NCBI:NM_004797.2 Database accession no. NM_004797.2 *
KATO KENICHI ET AL: "Serum total and high molecular weight adiponectin levels are correlated with the severity of diabetic retinopathy and nephropathy.", CLINICAL ENDOCRINOLOGY MAR 2008 LNKD- PUBMED:17970779, vol. 68, no. 3, March 2008 (2008-03-01), pages 442 - 449, XP002610837, ISSN: 1365-2265 *
SANDHU H S ET AL: "Measurement of circulating neuron-specific enolase mRNA in diabetes mellitus.", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES AUG 2008 LNKD- PUBMED:18837957, vol. 1137, August 2008 (2008-08-01), pages 258 - 263, XP002610835, ISSN: 1749-6632 *

Also Published As

Publication number Publication date
WO2011003623A2 (en) 2011-01-13

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