WO2011003239A1 - 无创膀胱压力测定装置及方法 - Google Patents

无创膀胱压力测定装置及方法 Download PDF

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Publication number
WO2011003239A1
WO2011003239A1 PCT/CN2009/072699 CN2009072699W WO2011003239A1 WO 2011003239 A1 WO2011003239 A1 WO 2011003239A1 CN 2009072699 W CN2009072699 W CN 2009072699W WO 2011003239 A1 WO2011003239 A1 WO 2011003239A1
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Prior art keywords
bladder
signal
unit
processor unit
bladder pressure
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French (fr)
Inventor
郭敏强
董涛
李同
罗笑南
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Sun Yat Sen University
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Sun Yat Sen University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/20—Measuring for diagnostic purposes; Identification of persons for measuring urological functions restricted to the evaluation of the urinary system
    • A61B5/202—Assessing bladder functions, e.g. incontinence assessment
    • A61B5/204—Determining bladder volume
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/20—Measuring for diagnostic purposes; Identification of persons for measuring urological functions restricted to the evaluation of the urinary system
    • A61B5/202—Assessing bladder functions, e.g. incontinence assessment
    • A61B5/205—Determining bladder or urethral pressure

Definitions

  • the present invention relates to a bladder pressure measuring device and method.
  • Bladder pressure measurement can understand the function of bladder detrusor and urethra during storage and urination, and it is important for the diagnosis and treatment of urinary system diseases such as urinary incontinence, benign prostatic hyperplasia, neurogenic bladder and overactive bladder. Clinical significance.
  • the existing pressure measurement method is to measure the bladder pressure by inserting a bladder pressure catheter into the urethra, and then to understand the relationship between bladder pressure and bladder volume during the storage and urination periods, and to determine the contraction of the detrusor and urethral sphincters. And the expansion function and the relationship between the two.
  • this kind of bladder pressure measurement technology has the following disadvantages: 1) Inserting the pressure catheter is an invasive operation, which has certain trauma to the patient; 2) It is difficult to intubate the patient such as elderly prostatic hyperplasia and urethral stricture, and the patient is subjectively abnormal. Pain; 3) Operation is extremely complicated, invasive detection of intercondylar length; 4) It is difficult to implement continuous dynamic bladder pressure detection; 5) It is easy to interfere with pressure measurement results due to human factors.
  • the technical problem to be solved by the present invention is to overcome the deficiencies of the prior art and to provide a bladder pressure measuring device and method which are painless, non-invasive, simple in operation and capable of realizing dynamic detection.
  • a non-invasive bladder pressure measuring device comprising a processor unit and a signal transmitting unit, a signal receiving unit, and a signal transmitting unit
  • the bladder sends a detection signal for detecting the volume of the bladder, and the detection signal is reflected by the bladder to become a reflected signal.
  • the signal receiving unit receives the reflected signal and feeds back to the processor unit, and the processor unit obtains the bladder pressure according to the reflected signal.
  • the processor unit is also connected to the display unit.
  • the processor unit is also connected to an interface unit.
  • the processor unit has a database that stores a correspondence between bladder volume change rate and bladder pressure.
  • a method for measuring non-invasive bladder pressure comprising the following steps:
  • [8] a) a step for detecting a detection signal of the bladder volume to the bladder;
  • Step b) and step c) also have a step e): a step for converting the reflected signal into a corresponding digital signal.
  • the bladder pressure is obtained based on the correspondence between the change rate of the bladder volume and the bladder pressure.
  • the detection signal is an ultrasonic signal.
  • a non-invasive bladder pressure measuring device comprising: a processor unit and a signal transmitting unit and a signal receiving unit connected thereto, the processor unit having a database storing a correspondence between a change rate of a bladder volume and a bladder pressure, the signal transmitting The unit sends an ultrasonic detecting signal for detecting the bladder volume to the bladder, and the detecting signal is reflected by the bladder to become a reflected signal, and the signal receiving unit receives the reflected signal and feeds back to the processor unit, and the processor unit obtains the bladder volume according to the reflected signal.
  • the rate of change which in turn leads to bladder pressure.
  • the beneficial effects of the invention are that the bladder pressure measurement is performed in a non-invasive manner, the pain of detecting sputum can be eliminated, the operation is simple, the dynamic monitoring can be realized, the influence of human factors can be avoided, and the measurement result is improved accurately. degree.
  • FIG. 1 is a block diagram showing the structure of a non-invasive bladder pressure measuring device according to the present embodiment
  • FIG. 2 is a flow chart of a method for measuring a non-invasive bladder pressure according to the present embodiment.
  • the non-invasive bladder pressure measuring device of the present embodiment includes a processor unit and both Connected signal transmitting unit, signal receiving unit, display unit and interface unit.
  • the signal sending unit is configured to send a detection signal for detecting the bladder volume to the bladder, and the detection signal can be used for detecting the liquid level of the urine in the bladder, the volume of the space occupied by the urine in the bladder or the volume of the remaining space in the bladder, the detection signal It can be a signal wave of ultrasound or other bands.
  • the detection signal is reflected by the bladder to form a reflected signal
  • the signal receiving unit receives the reflected signal, and converts the reflected signal of the analog format into a reflected signal in a digital format, and the converted reflected signal is transmitted to the processor unit.
  • the processor unit can receive the reflected signal transmitted by the signal receiving unit, and calculate a change rate of the bladder volume (that is, a change amount of the bladder volume per unit time) according to the reflected signal, and calculate the bladder pressure by the change rate of the bladder volume.
  • the processor unit may have a storage module for storing programs and data, and the storage module may store a database corresponding to the change rate of the bladder volume and the bladder pressure, and after calculating the rate of change of the bladder volume, the bladder may be directly obtained through the database. pressure.
  • the database may also store a correspondence between bladder volume change rate and prostate volume, sphincter muscle tone, and urethral pressure.
  • the processor unit can also have a built-in graphic reduction simulation module that can graphically display bladder pressure changes, prostate volume changes, or sphincter changes based on the rate of change in bladder volume.
  • the display unit is used to display various graphics, calculation parameters and calculation results, such as the existing CRT, LCD LED display.
  • the interface unit is used to realize the signal connection between the entire measuring device and the outside world, such as an existing wired or wireless network and a communication interface.
  • a certain number of patients with lower urinary tract dysfunction and a normal control group can be selected, and the bladder pressure and bladder volume, urine flow rate, and bladder volume change rate measured by the existing invasive bladder pressure measuring device can be separately selected.
  • the two establish the corresponding mathematical formula and model, and store the formula and model in the processor unit.
  • the signal transmitting unit can send a variety of signal waves, such as pulse square wave for distance measurement, continuous wave of urine height, and surface measurement.
  • the shape of the triangular wave or the like, the selection of the signal wave is controlled by the processor unit.
  • the determining device may comprise an input unit for receiving the control command, and the processor unit controls the signal transmitting unit to transmit the corresponding signal according to the input control command. wave.
  • the signal transmitting unit sends a detection signal to the bladder, and reflects the signal after the bladder reflects, and the signal receiving unit receives the reflected signal and converts it into a digital format.
  • the processor unit obtains the bladder based on the reflected signal
  • the volume change rate (the rate of increase in bladder volume during the urine storage period, and the rate of decrease in bladder volume during the urination period) is obtained by which the bladder pressure is obtained.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)

Description

说明书 无创膀胱压力测定装置及方法
技术领域
[1] 本发明是关于一种膀胱压力测定装置及方法。
背景技术
[2] 下尿路功能障碍是一种在人群中发病率较高的疾病， 给患者带来了很大的痛苦
。 据统计， 5%的儿童患有遗尿症， 15%的女性和 7%的男性成年人患有控尿功能 障碍性疾病。 在 75岁以上的老年男性中， 80%患有前列腺增生， 其中 50%以上的 前列腺体积明显增大， 前列腺增大则造成膀胱出口梗阻。 这些疾病均存在膀胱 的储尿与排尿功能障。 膀胱的充盈与排空是一个动态的过程， 尿流动力学的测 定可以反映下尿路疾病患者膀胱功能的动态变化。
[3] 膀胱压力测定可以了解膀胱在储尿期与排尿期吋逼尿肌和尿道的功能， 对尿失 禁、 前列腺增生、 神经源性膀胱、 膀胱过度活动症等泌尿系统疾病的诊治有重 大的临床意义。 现有压力测定方法是通过在尿道插入膀胱测压导尿管来测量膀 胱压力， 进而了解在储尿期与排尿期吋膀胱压力与膀胱容积之间的关系， 判断 逼尿肌与尿道括约肌的收缩与扩张功能及二者之间的关系。 但是， 该种膀胱压 力测定技术存在如下缺点： 1)插测压导尿管是有创性操作， 对病人有一定创伤； 2)老年前列腺增生、 尿道狭窄等患者插管困难， 病人主观感觉异常痛苦； 3)操作 异常复杂， 有创检测吋间长； 4)难以实施连续动态膀胱压力检测； 5)容易因人为 因素干扰压力测量结果。
对发明的公开
技术问题
[4] 本发明所要解决的技术问题是， 克服现有技术的不足， 提供一种无痛、 无创、 操作简单且能实现动态检测的膀胱压力测定装置及方法。
技术解决方案
[5] 本发明解决其技术问题所釆用的技术方案是： 一种无创膀胱压力测定装置， 包 括处理器单元及与其均连接的信号发送单元、 信号接收单元， 信号发送单元向 膀胱发送探测膀胱容积的探测信号， 该探测信号经膀胱反射后成为反射信号， 信号接收单元接收该反射信号并反馈到处理器单元， 处理器单元根据该反射信 号得出膀胱压力。
[6] 所述处理器单元还连接有显示单元。 所述处理器单元还连接有接口单元。 所述 处理器单元具有存储有膀胱容积变化率与膀胱压力对应关系的数据库。
[7] 一种无创膀胱压力测定方法， 包括如下步骤：
[8] a)用于向膀胱发射探测膀胱容积的探测信号的步骤；
[9] b)用于接收膀胱反射信号的步骤；
[10] c)用于根据反射信号得出膀胱容积变化率的步骤；
[11] d)用于根据膀胱容积变化率得出膀胱压力的步骤。
[12] 所述步骤 b)和步骤 c)之间还具有步骤 e): 用于将反射信号转换为对应数字信号 的步骤。 所述的步骤 d)中， 根据膀胱容积变化率和膀胱压力的对应关系得出膀胱 压力。 所述步骤 a)中， 探测信号为超声波信号。
[13] 一种无创膀胱压力测定装置， 包括处理器单元及与其均连接的信号发送单元、 信号接收单元， 该处理器单元具有存储有膀胱容积变化率与膀胱压力对应关系 的数据库， 该信号发送单元向膀胱发送探测膀胱容积的超声波探测信号， 该探 测信号经膀胱反射后成为反射信号， 该信号接收单元接收该反射信号并反馈到 处理器单元， 该处理器单元根据该反射信号得出膀胱容积变化率、 进而得出膀 胱压力。
有益效果
[14] 本发明的有益效果是， 釆用无创的方式进行膀胱压力测定， 能消除检测吋的痛 苦， 操作简单， 能够实现动态的监测， 并且能避免人为因素的影响， 提高了测 定结果的准确度。
附图说明
[15] 图 1是本实施方式无创膀胱压力测定装置的结构框图；
[16] 图 2是本实施方式无创膀胱压力测定方法的流程框图。
本发明的实施方式
[17] 如图 1及图 2所示， 本实施方式无创膀胱压力测定装置包括处理器单元及与其均 连接的信号发送单元、 信号接收单元、 显示单元及接口单元。 信号发送单元用 于向膀胱发送探测膀胱容积的探测信号， 该探测信号可以用来探测膀胱内尿液 的液面、 膀胱内尿液所占空间的容积或膀胱内剩余空间的容积， 该探测信号可 以为超声波或其它波段的信号波。 探测信号经膀胱反射后形成反射信号， 信号 接收单元接收该反射信号， 并将该模拟格式的反射信号转换为数字格式的反射 信号， 转换后的反射信号传送至处理器单元。 处理器单元可以接收信号接收单 元传送来的反射信号， 根据该反射信号计算得出膀胱容积变化率 (即单位吋间内 膀胱容积的变化量)， 通过该膀胱容积变化率计算得出膀胱压力。 处理器单元可 以具有用于存储程序和数据的存储模块， 该存储模块可以存储有膀胱容积变化 率与膀胱压力对应关系的数据库， 计算得出膀胱容积变化率后， 可通过该数据 库直接得出膀胱压力。 该数据库还可以存储有膀胱容积变化率与前列腺体积、 括约肌肌张力、 尿道压力之间的对应关系。 处理器单元还可以内置有图形还原 仿真模块， 根据膀胱容积变化率， 可以用图形的方式直观显示出膀胱压力变化 、 前列腺体积变化或括约肌变化。 显示单元用于显示各种图形、 计算参数及计 算结果， 显示单元如现有的 CRT、 LCD LED显示屏。 接口单元用于实现整个测 定装置与外界的信号连接， 该接口单元如现有的有线或无线网络、 通信接口。 对于数据库的获得， 可以分别选取一定样本数量的下尿路功能障碍患者及正常 人对照组， 利用现有有创膀胱压力测定装置测定的膀胱压力与膀胱容积、 尿流 率、 膀胱容积变化率之间的对应关系， 建立相对应的数学公式及模型， 并将该 公式及模型存储在处理器单元中。
[18] 另外， 由于待测对象的特殊性质， 如不同性别、 体质、 年龄， 信号发送单元可 以发送多种信号波， 如测距用的脉冲方波、 测尿液高度的连续波、 测表面形状 的三角波等， 信号波的选取由处理器单元进行控制， 对应的， 该测定装置可以 包括用于接收控制指令的输入单元， 根据输入的控制指令， 处理器单元控制信 号发送单元发送对应的信号波。
[19] 进行膀胱压力测定吋， 将测定装置置于待测对象膀胱附近， 信号发送单元发送 探测信号到膀胱， 经膀胱反射后形成反射信号， 信号接收单元接收反射信号并 将其转换成数字格式后传送到处理器单元， 处理器单元根据反射信号得到膀胱 容积变化率 (在储尿期计算膀胱容积增大速率， 在排尿期计算膀胱容积减小速率) ， 通过该容积变化率得到膀胱压力。
以上内容是结合具体的优选实施方式对本发明所作的进一步详细说明， 不能认 定本发明的具体实施只局限于这些说明。 对于本发明所属技术领域的普通技术 人员来说， 在不脱离本发明构思的前提下， 还可以做出若干简单推演或替换， 都应当视为属于本发明的保护范围。

Claims

权利要求书
[1] 一种无创膀胱压力测定装置， 其特征在于： 包括处理器单元及与其均连接 的信号发送单元、 信号接收单元， 信号发送单元向膀胱发送探测膀胱容积 的探测信号， 该探测信号经膀胱反射后成为反射信号， 信号接收单元接收 该反射信号并反馈到处理器单元， 处理器单元根据该反射信号得出膀胱压 力。
[2] 根据权利要求 1所述的无创膀胱压力测定装置， 其特征在于： 所述处理器单 元还连接有显示单元。
[3] 根据权利要求 2所述的无创膀胱压力测定装置， 其特征在于： 所述处理器单 元还连接有接口单元。
[4] 根据权利要求 1-3中任意一项所述的无创膀胱压力测定装置， 其特征在于： 所述处理器单元具有存储有膀胱容积变化率与膀胱压力对应关系的数据库
[5] 一种无创膀胱压力测定方法， 其特征在于： 包括如下步骤：
a)用于向膀胱发射探测膀胱容积的探测信号的步骤；
b)用于接收膀胱反射信号的步骤；
c)用于根据反射信号得出膀胱容积变化率的步骤；
d)用于根据膀胱容积变化率得出膀胱压力的步骤。
[6] 根据权利要求 5所述的无创膀胱压力测定方法， 其特征在于： 所述步骤 b)和 步骤 c)之间还具有步骤 e): 用于将反射信号转换为对应数字信号的步骤。
[7] 根据权利要求 5所述的无创膀胱压力测定方法， 其特征在于： 所述的步骤 d) 中， 根据膀胱容积变化率和膀胱压力的对应关系得出膀胱压力。
[8] 根据权利要求 5-7中任意一项所述的无创膀胱压力测定方法， 其特征在于： 所述步骤 a)中， 探测信号为超声波信号。
[9] 一种无创膀胱压力测定装置， 其特征在于： 包括处理器单元及与其均连接 的信号发送单元、 信号接收单元， 该处理器单元具有存储有膀胱容积变化 率与膀胱压力对应关系的数据库， 该信号发送单元向膀胱发送探测膀胱容 积的超声波探测信号， 该探测信号经膀胱反射后成为反射信号， 该信号接 收单元接收该反射信号并反馈到处理器单元， 该处理器单元根据该反射信 号得出膀胱容积变化率、 进而得出膀胱压力。
[10] 根据权利要求 9所述的无创膀胱压力测定装置， 其特征在于： 所述处理器单 元还连接有显示单元。
[11] 根据权利要求 9或 10所述的无创膀胱压力测定装置， 其特征在于： 所述处理 器单元还连接有接口单元。
PCT/CN2009/072699 2009-07-09 2009-07-09 无创膀胱压力测定装置及方法 Ceased WO2011003239A1 (zh)

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CN103908706A (zh) * 2014-04-11 2014-07-09 李博 一种自动导尿系统

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