WO2010141690A3 - Indane analogs and use as pharmaceutical agents and process of making - Google Patents
Indane analogs and use as pharmaceutical agents and process of making Download PDFInfo
- Publication number
- WO2010141690A3 WO2010141690A3 PCT/US2010/037216 US2010037216W WO2010141690A3 WO 2010141690 A3 WO2010141690 A3 WO 2010141690A3 US 2010037216 W US2010037216 W US 2010037216W WO 2010141690 A3 WO2010141690 A3 WO 2010141690A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- indane
- disease
- analogs
- making
- pharmaceutical agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Abstract
This invention relates to novel indane analogues that are useful in the treatment of diseases and disorders such as treating and/or preventing diabetes and related disorders such as Syndrome X, impaired glucose tolerance, impaired fasting glucose, and hyperinsulinemia obesity, atherosclerotic disease, dyslipidemia, and related disorders such as hypertriglyceridemia, low HDL cholesterol, and hypercholesteremia, cardiovascular disease, cerebrovascular disease, psoriasis, or Alzheimer's disease. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18414909P | 2009-06-04 | 2009-06-04 | |
US61/184,149 | 2009-06-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2010141690A2 WO2010141690A2 (en) | 2010-12-09 |
WO2010141690A3 true WO2010141690A3 (en) | 2011-01-27 |
Family
ID=43298504
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2010/037216 WO2010141690A2 (en) | 2009-06-04 | 2010-06-03 | Indane analogs and use as pharmaceutical agents and process of making |
Country Status (2)
Country | Link |
---|---|
TW (1) | TW201102372A (en) |
WO (1) | WO2010141690A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9555012B2 (en) * | 2012-08-09 | 2017-01-31 | Dynamis Therapeutics, Inc. | Methods for maintaining or improving health, well-being and/or a physiological function in a subject |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002080935A1 (en) * | 2001-04-04 | 2002-10-17 | Ortho Mcneil Pharmaceutical, Inc. | Combination therapy comprising glucose reabsorption inhibitors and retinoid-x receptor modulators |
WO2003011842A1 (en) * | 2001-07-27 | 2003-02-13 | Bayer Pharmaceuticals Corporation | Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation |
EP1644320B1 (en) * | 2003-07-03 | 2008-01-16 | Eli Lilly And Company | Indane derivates as muscarinic receptor agonists |
-
2010
- 2010-06-03 WO PCT/US2010/037216 patent/WO2010141690A2/en active Application Filing
- 2010-06-04 TW TW099118309A patent/TW201102372A/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002080935A1 (en) * | 2001-04-04 | 2002-10-17 | Ortho Mcneil Pharmaceutical, Inc. | Combination therapy comprising glucose reabsorption inhibitors and retinoid-x receptor modulators |
WO2003011842A1 (en) * | 2001-07-27 | 2003-02-13 | Bayer Pharmaceuticals Corporation | Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation |
EP1644320B1 (en) * | 2003-07-03 | 2008-01-16 | Eli Lilly And Company | Indane derivates as muscarinic receptor agonists |
Also Published As
Publication number | Publication date |
---|---|
WO2010141690A2 (en) | 2010-12-09 |
TW201102372A (en) | 2011-01-16 |
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