WO2010139959A3 - Alginate oligomers for the inhibition of microbial adherence to surfaces - Google Patents
Alginate oligomers for the inhibition of microbial adherence to surfaces Download PDFInfo
- Publication number
- WO2010139959A3 WO2010139959A3 PCT/GB2010/001099 GB2010001099W WO2010139959A3 WO 2010139959 A3 WO2010139959 A3 WO 2010139959A3 GB 2010001099 W GB2010001099 W GB 2010001099W WO 2010139959 A3 WO2010139959 A3 WO 2010139959A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- inhibition
- alginate oligomers
- microbial adherence
- adherence
- microorganism
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/14—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
- A01N43/16—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
- A61L29/085—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
Abstract
The present invention provides a method for inhibiting the adherence of a microorganism to a surface, said method comprising contacting said microorganism and/or the surface with an alginate oligomer, wherein said alginate oligomer has a number average degree of polymerisation of 8-50 and wherein at least 90% of the monomer residues are guluronate. Both medical and non-medical uses are provided.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0909529A GB0909529D0 (en) | 2009-06-03 | 2009-06-03 | Alginate oligomers for the inhibition of microbial adherence to surfaces |
GB0909529.0 | 2009-06-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2010139959A2 WO2010139959A2 (en) | 2010-12-09 |
WO2010139959A3 true WO2010139959A3 (en) | 2011-07-07 |
Family
ID=40902513
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2010/001099 WO2010139959A2 (en) | 2009-06-03 | 2010-06-03 | Alginate oligomers for the inhibition of microbial adherence to surfaces |
Country Status (2)
Country | Link |
---|---|
GB (1) | GB0909529D0 (en) |
WO (1) | WO2010139959A2 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5639475B2 (en) | 2007-11-27 | 2014-12-10 | アルギファルマ アイピーアール エーエス | Use of alginate oligomers in combating biofilms |
AU2014372566B2 (en) * | 2013-12-23 | 2017-07-20 | Norwegian University Of Science And Technology | Uses of oligouronates in cancer treatment |
US20160361342A1 (en) * | 2014-02-28 | 2016-12-15 | Algipharama As | Use of alginate oligomers in the treatment of cystic fibrosis and other conditions associated with defective cftr ion channel function |
GB201517639D0 (en) * | 2015-10-06 | 2015-11-18 | Algipharma As | Use of alginate oligomers to treat or prevent microbial overgrowth in the intestinal tract |
WO2018127819A1 (en) | 2017-01-03 | 2018-07-12 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing alginates as biodegradable antibacterial scaffolds and methods pertaining thereto |
CA3055474A1 (en) | 2017-03-28 | 2018-10-04 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing polyaminoglycosides as biodegradable antibacterial scaffolds and methods pertaining thereto |
JP2021515083A (en) | 2018-03-06 | 2021-06-17 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒルThe University Of North Carolina At Chapel Hill | Nitric oxide-releasing cyclodextrin as a biodegradable antibacterial scaffold and related methods |
US11421044B2 (en) | 2018-12-28 | 2022-08-23 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing antibacterial polymers and scaffolds fabricated therefrom and methods pertaining thereto |
CN115197881A (en) * | 2022-07-22 | 2022-10-18 | 苏州鑫泷生态环境有限公司 | Compound microbial agent for photovoltaic wastewater treatment and preparation method and application thereof |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0506325A1 (en) * | 1991-03-27 | 1992-09-30 | Pronova Biopolymer As | Guluronic acid polymers and use of same for inhibition of cytokine production |
US5683991A (en) * | 1993-09-10 | 1997-11-04 | Laevosan-Gesellschaft | Blocking the attachment of germs to human cells |
WO2006112714A2 (en) * | 2005-04-21 | 2006-10-26 | N.V. Nutricia | Uronic acid and probiotics |
WO2008125828A2 (en) * | 2007-04-12 | 2008-10-23 | Ntnu Technology Transfer As | Oligo-guluronate and galacturonate compositions |
WO2009068841A2 (en) * | 2007-11-27 | 2009-06-04 | Algipharma Ipr As | Use of alginate oligomers in combating biofilms |
WO2010139958A1 (en) * | 2009-06-03 | 2010-12-09 | Algipharma Ipr As | Anti-microbial alginate oligomers |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU7221691A (en) | 1990-01-23 | 1991-08-21 | Terje Espevik | Mannuronic acid containing alginate wound healing composition and method |
US5169840A (en) | 1991-03-27 | 1992-12-08 | Nobipols Forskningsstiftelse | Diequatorially bound β-1, 4 polyuronates and use of same for cytokine stimulation |
CA2106609A1 (en) | 1992-09-28 | 1994-03-29 | Irene Yeatman Aldridge | Proteases to inhibit and remove biofilm |
GB9221163D0 (en) | 1992-10-08 | 1992-11-25 | Nobipol And Protan Biopolymer | Dna compounds |
NO305033B1 (en) | 1997-05-09 | 1999-03-22 | Algipharma As | Process for the preparation of uric acid blocks from alginate |
US7494669B2 (en) | 2001-02-28 | 2009-02-24 | Carrington Laboratories, Inc. | Delivery of physiological agents with in-situ gels comprising anionic polysaccharides |
NO326145B1 (en) | 2001-11-30 | 2008-10-06 | Fmc Biopolymer As | Method of stimulating weight gain in mammals, birds and reptiles. |
NO20023581D0 (en) | 2002-07-26 | 2002-07-26 | Fmc Biopolymer As | New mutant strains of Pseudomonas fluorescence and variants thereof, methods of production and use thereof for the production of alginate |
GB2430881B (en) | 2005-10-06 | 2010-10-13 | Ntnu Technology Transfer As | Oligoelectrolyte polyols for the treatment of mucosal hyperviscosity |
-
2009
- 2009-06-03 GB GB0909529A patent/GB0909529D0/en not_active Ceased
-
2010
- 2010-06-03 WO PCT/GB2010/001099 patent/WO2010139959A2/en active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0506325A1 (en) * | 1991-03-27 | 1992-09-30 | Pronova Biopolymer As | Guluronic acid polymers and use of same for inhibition of cytokine production |
US5683991A (en) * | 1993-09-10 | 1997-11-04 | Laevosan-Gesellschaft | Blocking the attachment of germs to human cells |
WO2006112714A2 (en) * | 2005-04-21 | 2006-10-26 | N.V. Nutricia | Uronic acid and probiotics |
WO2008125828A2 (en) * | 2007-04-12 | 2008-10-23 | Ntnu Technology Transfer As | Oligo-guluronate and galacturonate compositions |
WO2009068841A2 (en) * | 2007-11-27 | 2009-06-04 | Algipharma Ipr As | Use of alginate oligomers in combating biofilms |
WO2010139958A1 (en) * | 2009-06-03 | 2010-12-09 | Algipharma Ipr As | Anti-microbial alginate oligomers |
Non-Patent Citations (2)
Title |
---|
KITAMIKADO M ET AL: "Bacteriostatic Action of Oligosaccharides Prepared from Alginate by Enzymatic Degradation", NIPPON SUISAN GAKKAISHI - BULLETIN OF THE JAPANESE SOCIETY OFSCIENTIFIC FISHERIES, NIPPON SUISAN GAKKAI, TOKYO, JP, vol. 59, no. 2, 28 February 1993 (1993-02-28), pages 315 - 320, XP002575207, ISSN: 0021-5392 * |
XIAOKE HU ET AL: "Antibacterial activity of lyase-depolymerized products of alginate", JOURNAL OF APPLIED PHYCOLOGY, KLUWER ACADEMIC PUBLISHERS, DO, vol. 17, no. 1, 1 January 2005 (2005-01-01), pages 57 - 60, XP019247779, ISSN: 1573-5176 * |
Also Published As
Publication number | Publication date |
---|---|
GB0909529D0 (en) | 2009-07-15 |
WO2010139959A2 (en) | 2010-12-09 |
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