WO2010136819A3 - Dry powder fibrin sealant - Google Patents

Dry powder fibrin sealant Download PDF

Info

Publication number
WO2010136819A3
WO2010136819A3 PCT/GB2010/050910 GB2010050910W WO2010136819A3 WO 2010136819 A3 WO2010136819 A3 WO 2010136819A3 GB 2010050910 W GB2010050910 W GB 2010050910W WO 2010136819 A3 WO2010136819 A3 WO 2010136819A3
Authority
WO
WIPO (PCT)
Prior art keywords
fibrin sealant
dry powder
powder fibrin
microparticles
sealant
Prior art date
Application number
PCT/GB2010/050910
Other languages
French (fr)
Other versions
WO2010136819A2 (en
Inventor
Nicola Whitfield
Original Assignee
Quadrant Drug Delivery Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quadrant Drug Delivery Limited filed Critical Quadrant Drug Delivery Limited
Publication of WO2010136819A2 publication Critical patent/WO2010136819A2/en
Publication of WO2010136819A3 publication Critical patent/WO2010136819A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)

Abstract

A fibrin sealant comprises a mixture of first microparticles that comprise fibrinogen, and second microparticles that comprise thrombin, wherein either or each of the microparticles is solid and has a particle size of at least 50 μm.
PCT/GB2010/050910 2009-05-28 2010-05-28 Dry powder fibrin sealant WO2010136819A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0909129A GB0909129D0 (en) 2009-05-28 2009-05-28 Dry powder fibrin sealant
GB0909129.9 2009-05-28

Publications (2)

Publication Number Publication Date
WO2010136819A2 WO2010136819A2 (en) 2010-12-02
WO2010136819A3 true WO2010136819A3 (en) 2011-01-20

Family

ID=40863062

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2010/050910 WO2010136819A2 (en) 2009-05-28 2010-05-28 Dry powder fibrin sealant

Country Status (2)

Country Link
GB (1) GB0909129D0 (en)
WO (1) WO2010136819A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2556842A1 (en) 2011-08-11 2013-02-13 Bioftalmik, S.L. Composition in the form of film comprising fibrinogen and a fibrinogen activator and the applications thereof
US20160015792A1 (en) * 2013-03-07 2016-01-21 Profibrix Bv Powder formulation comprising thrombin and fibrinogen

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4427651A (en) * 1981-06-25 1984-01-24 Serapharm Michael Stroetmann Enriched plasma derivative for enhancement of wound closure and coverage
WO1997044015A1 (en) * 1996-05-17 1997-11-27 Andaris Limited Microparticles and their use in wound therapy
US20020037323A1 (en) * 1998-10-27 2002-03-28 Glatt Process Technology Gmbh Fibrin tissue adhesive formulation and process for its preparation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4427651A (en) * 1981-06-25 1984-01-24 Serapharm Michael Stroetmann Enriched plasma derivative for enhancement of wound closure and coverage
WO1997044015A1 (en) * 1996-05-17 1997-11-27 Andaris Limited Microparticles and their use in wound therapy
US20020037323A1 (en) * 1998-10-27 2002-03-28 Glatt Process Technology Gmbh Fibrin tissue adhesive formulation and process for its preparation

Also Published As

Publication number Publication date
WO2010136819A2 (en) 2010-12-02
GB0909129D0 (en) 2009-07-01

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