WO2010122474A3 - A medicinal antifungal and steroid cream incorporating a biopolymer and a process to make it - Google Patents
A medicinal antifungal and steroid cream incorporating a biopolymer and a process to make it Download PDFInfo
- Publication number
- WO2010122474A3 WO2010122474A3 PCT/IB2010/051690 IB2010051690W WO2010122474A3 WO 2010122474 A3 WO2010122474 A3 WO 2010122474A3 IB 2010051690 W IB2010051690 W IB 2010051690W WO 2010122474 A3 WO2010122474 A3 WO 2010122474A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- skin
- biopolymer
- treating fungal
- infections
- chitosan
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention is directed to a composition for treating fungal skin infections & skin inflammation, along with skin rejuvenation containing a) a biopolymer in the form of Chitosan, b) a combination of active pharmaceutical ingredients (APIs), namely Miconazole Nitrate & Mometasone Furoate, used in treating fungal skin infections & skin inflammations, c) a cream base containing primary and secondary emulsifiers, waxy materials, co -solvents, acids, preservatives, buffering agents, anti oxidants, chelating agents, and humectants, and d) water. The active ingredients, namely chitosan, a corticosteroid in the form of Mometasone Furoate, and an antifungal agent in the form of Miconazole Nitrate, are incorporated in cream base for use in treating fungal skin infections and skin inflammation due to allergy & itching, & wounds on human skin involving contacting human skin with the above identified composition.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1024MU2009 | 2009-04-20 | ||
IN1024/MUM/2009 | 2009-04-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2010122474A2 WO2010122474A2 (en) | 2010-10-28 |
WO2010122474A3 true WO2010122474A3 (en) | 2010-12-29 |
Family
ID=42830693
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2010/051690 WO2010122474A2 (en) | 2009-04-20 | 2010-04-19 | A medicinal antifungal and steroid cream incorporating a biopolymer and a process to make it |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2010122474A2 (en) |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0368253A2 (en) * | 1988-11-08 | 1990-05-16 | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (a New York corporation) | Delivery system for pharmaceutical or therapeutic actives |
US5461068A (en) * | 1993-09-29 | 1995-10-24 | Corwood Laboratories, Inc. | Imidazole derivative tincture and method of manufacture |
WO2003086348A1 (en) * | 2002-04-08 | 2003-10-23 | Dermcare-Vet Pty Ltd | Allergic dermatitis formulation and method of treatment |
US20060275218A1 (en) * | 2003-08-04 | 2006-12-07 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
US20070196452A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Flux-enabling compositions and methods for dermal delivery of drugs |
US20080206161A1 (en) * | 2002-10-25 | 2008-08-28 | Dov Tamarkin | Quiescent foamable compositions, steroids, kits and uses thereof |
-
2010
- 2010-04-19 WO PCT/IB2010/051690 patent/WO2010122474A2/en active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0368253A2 (en) * | 1988-11-08 | 1990-05-16 | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (a New York corporation) | Delivery system for pharmaceutical or therapeutic actives |
US5461068A (en) * | 1993-09-29 | 1995-10-24 | Corwood Laboratories, Inc. | Imidazole derivative tincture and method of manufacture |
WO2003086348A1 (en) * | 2002-04-08 | 2003-10-23 | Dermcare-Vet Pty Ltd | Allergic dermatitis formulation and method of treatment |
US20080206161A1 (en) * | 2002-10-25 | 2008-08-28 | Dov Tamarkin | Quiescent foamable compositions, steroids, kits and uses thereof |
US20060275218A1 (en) * | 2003-08-04 | 2006-12-07 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
US20070196452A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Flux-enabling compositions and methods for dermal delivery of drugs |
Non-Patent Citations (3)
Title |
---|
MARRAS F: "THERAPEUTIC USEFULNESS OF A CORTICOSTEROID ANTIBACTERIAL AND ANTIFUNGAL COMBINATION IN SKIN DISEASES OF VARIOUS ORIGINS", PHARMATHERAPEUTICA, CLAYTON-WRAY PUBLICATIONS, LONDON, GB, vol. 4, no. 2, 1 January 1985 (1985-01-01), pages 88 - 91, XP009133482, ISSN: 0308-051X * |
PAZZAGLIA A: "THERAPEUTIC EFFECTS AND TOLERANCE OF AN EXTEMPORE COMBINATION OF AN ANTIBACTERIAL ANTI-INFLAMMATORY AND ANTIMYCOTIC CREAM IN SKIN DISEASES OF VARIOUS ORIGINS", PHARMATHERAPEUTICA, CLAYTON-WRAY PUBLICATIONS, LONDON, GB, vol. 4, no. 2, 1 January 1985 (1985-01-01), pages 122 - 125, XP009133483, ISSN: 0308-051X * |
RAVI KUMAR M N V: "A review of chitin and chitosan applications", REACTIVE & FUNCTIONAL POLYMERS, ELSEVIER SCIENCE PUBLISHERS BV, NL LNKD- DOI:10.1016/S1381-5148(00)00038-9, vol. 46, no. 1, 1 November 2000 (2000-11-01), pages 1 - 27, XP004224437, ISSN: 1381-5148 * |
Also Published As
Publication number | Publication date |
---|---|
WO2010122474A2 (en) | 2010-10-28 |
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