WO2010119919A1

WO2010119919A1 - Chemical solution feeder

Info

Publication number: WO2010119919A1
Application number: PCT/JP2010/056747
Authority: WO
Inventors: 茂根本
Original assignee: 株式会社根本杏林堂
Priority date: 2009-04-15
Filing date: 2010-04-15
Publication date: 2010-10-21
Also published as: JPWO2010119919A1; JP5492873B2

Abstract

The leading end portion of a feeder head (110) having a syringe assembly (200) removably attached thereto is provided with: a syringe receiver (120) which has a recessed inner surface so as to support the outer circumferential surface of the syringe assembly (200); and a syringe holder (140) which affixes the syringe assembly (200) on the feeder head (110) by holding a flange (271) formed at the end for the syringe assembly (200). The syringe receiver (120) has transparency to such an extent that whether a chemical solution applied in the syringe assembly (200) includes bubbles or not can be visually checked through the syringe receiver (120).

Description

Chemical injection device

The present invention relates to a chemical solution injection device in which a syringe having a cylinder and a piston is detachably attached, and a chemical solution is injected into a subject by operating the piston of the attached syringe.

Medical diagnostic imaging apparatuses include a CT (Computed Tomography) scanner, an MRI (Magnetic Resonance Imaging) apparatus, a PET (Positron Emission Tomography) apparatus, an angiographic apparatus, and an MRA (MR Angio) apparatus. When taking a CT image of a subject using these devices, a chemical solution such as a contrast medium or physiological saline is often injected into the subject.

It is common to automatically inject a chemical solution into a subject using a chemical solution injection device. The chemical solution injector includes an injection head to which a syringe filled with a chemical solution is detachably mounted, and an injection control unit that controls the operation of the injection head. The syringe has a cylinder and a piston inserted in the cylinder so as to be movable in the axial direction, and the liquid medicine is filled in the cylinder.

The injection head is attached to the injection head, a concave syringe receiver on which the syringe is placed by receiving the outer peripheral surface of the syringe, a flange holder for fixing the syringe to the injection head by holding a flange formed at the end of the cylinder, and A piston drive mechanism for pushing the piston of the syringe into the cylinder is provided. After connecting the injection needle to the tip of the cylinder via the extension tube and puncturing the injection needle into the blood vessel of the subject, the piston drive mechanism pushes the piston into the cylinder, so that the liquid medicine filled in the syringe is removed. Can be injected into a subject.

∙ Air bubbles may be mixed in the syringe. Therefore, in the conventional chemical solution injection device, various devices have been made to prevent the air bubbles mixed in the syringe from being injected into the subject.

For example, Patent Literature 1 and Patent Literature 2 disclose a chemical liquid injector configured to prevent a chemical liquid injection from being performed unless a predetermined operation (bubble elimination operation) for eliminating bubbles from a syringe is completed. ing. Specifically, this bubble elimination operation is an operation including a state in which the injection head equipped with the syringe is in a posture such that the tip of the syringe faces upward, and in this state, the piston of the syringe is pushed into the cylinder by a predetermined amount. It is. According to this chemical solution injection device, it is possible to prevent the chemical solution injection from being erroneously executed with a syringe in which bubble elimination has not been completed.

Patent Document 1: International Publication No. 06/068171 Patent Document 2: International Publication No. 06/1097779

However, in the chemical liquid injectors disclosed in Patent Documents 1 and 2, when the bubble elimination operation is completed, the chemical liquid injection can be executed regardless of whether or not the bubbles are actually eliminated. In most cases, bubbles are eliminated by the bubble elimination operation, but rarely, the bubbles may not be completely eliminated. Therefore, it is necessary for the operator to visually check whether or not the bubbles are completely removed after the bubble removing operation. However, since the conventional chemical solution injector is configured to receive a part of the outer peripheral surface of the syringe in the concave syringe receiver as described above, depending on the posture of the injection head, the syringe receiver may become an obstacle. In some cases, it was difficult to visually confirm the state of the chemical solution inside.

Therefore, an object of the present invention is to provide a chemical liquid injector capable of visually confirming the state of the chemical liquid in the syringe from any circumferential direction of the syringe with the syringe attached.

In order to achieve the above object, the chemical injection device of the present invention is a chemical injection device having an injection head to which a syringe assembly is detachably attached.
The injection head secures the syringe assembly to the injection head by holding a syringe receiver configured with a concave inner surface to support the outer peripheral surface of the syringe assembly and a flange formed at the distal end of the syringe assembly. The syringe holder has a syringe holder at the tip, and the syringe receiver can be visually confirmed through the syringe receiver whether or not at least the portion having the concave inner surface contains bubbles in the liquid medicine filled in the syringe assembly. It is characterized by having translucency to the extent.

In the chemical liquid injector of the present invention, the syringe receiver may contain a translucent heater for keeping the chemical liquid in the syringe assembly attached to the injection head and not impeding the translucency of the syringe receiver. preferable. In this case, it is preferable that the translucent heater is flexible and curved in accordance with the concave shape of the syringe receiver.

The injection head is configured to mount the two syringe assemblies in parallel, and the flange holder includes three shafts arranged in parallel at an interval larger than the diameter of the flange, and a flange. A base member formed with two arc-shaped flange receiving recesses that receive the outer peripheral surface of the shaft at a position between the shafts, and two outer shafts are rotatably supported so as to open and close the flange receiving recesses. Then, the engaging structure that engages with the central shaft may have two flange pressing members provided at the respective free ends.

According to the present invention, since the syringe receiver provided at the distal end portion of the injection head has translucency as described above, the syringe assembly is filled regardless of the posture of the injection head. It can be visually confirmed whether or not bubbles are mixed in the chemical solution. In addition, since the holder that holds the syringe assembly on the injection head holds the flange formed at the end of the syringe assembly, the holder does not hinder the visual check of the mixing of bubbles in the chemical solution.

1 is a perspective view of a fluoroscopic imaging system according to an embodiment of the present invention. It is a perspective view of the chemical injection device shown in FIG. It is a perspective view which shows the injection | pouring head shown in FIG. 2 with the syringe with which it is mounted | worn, and a pressure | voltage resistant cover. FIG. 4 is an enlarged perspective view of a flange receiver and a syringe holder of the injection head shown in FIG. 3. It is a perspective view explaining the mounting | wearing procedure of the syringe assembly to the injection | pouring head shown in FIG. 2, and shows the state which has a flange pressing member in an open position. It is a perspective view explaining the mounting | wearing procedure of the syringe assembly to the injection head shown in FIG. 2, and shows the state which has a flange pressing member in a closed position.

Referring to FIG. 1, there is shown a fluoroscopic imaging system 1000 according to an embodiment of the present invention having a chemical injection device 100 and a CT angio device 300 which is a fluoroscopic imaging device. The CT angio apparatus 300 includes an imaging unit 301 that executes an imaging operation and an imaging control unit 302 that controls the operation of the imaging unit 301, which are connected to each other via a communication network.

For example, as shown in FIG. 2, the chemical injection device 100 includes an injection head 110 that is mounted on an upper portion of a stand 111 via an arm 112, and an injection control unit 101 that is connected to the injection head 110 with a cable 102. ing. The injection control unit 101 includes a main operation panel 103, a touch panel 104 serving as a display unit and an input unit, a hand unit 107 serving as an auxiliary input unit connected to the main body of the injection control unit 101 with a cable 108, and the like. ing.

As shown in FIG. 3, the injection head 110 is detachably mounted with two sets of syringe assemblies 200 (in FIG. 3, only one set of syringe assemblies 200 is shown for simplicity). The syringe assembly 200 includes a syringe 220 and a pressure-resistant cover 270 into which the syringe 220 is inserted. The syringe 220 is a syringe 220 generally called a rodless syringe, and includes a cylinder 221 having a flange 221a formed at the end and a nozzle portion 221b formed at the distal end, and a piston 222 inserted into the cylinder 221. ing.

The syringe 220 is filled with a chemical solution, and when the piston 222 is moved toward the tip of the cylinder 221, the filled chemical solution is pushed out from the syringe 220 through the nozzle portion 221b. By connecting an extension tube having an injection needle connected to the tip to the nozzle part 221b, the injection needle can be punctured into the blood vessel of the subject, and the drug solution filled in the syringe 220 can be injected into the subject. Examples of the chemical solution filled in the syringe 220 include a contrast medium and physiological saline. For example, one syringe 220 can be filled with a contrast medium, and the other can be filled with physiological saline.

The pressure-resistant cover 270 is a part configured in a substantially cylindrical shape so that the cylinder 221 is inserted therein, and restricts expansion due to an increase in internal pressure of the cylinder 221 during injection of a chemical solution. Therefore, the pressure-resistant cover 270 is formed with a thickness having a strength that can sufficiently withstand the internal pressure acting on the syringe 220 during the injection of the chemical solution. An opening is formed at the tip of the pressure-resistant cover 270, and the cylinder 221 is held by the pressure-resistant cover 270 with the nozzle portion 221b protruding from the opening. Further, a cover flange 271 having a recess for receiving the flange 221a of the cylinder 221 is formed at the end of the pressure-resistant cover 270. The pressure-resistant cover 270 is formed of a transparent member so that it can be visually confirmed through the pressure-resistant cover 270 whether or not bubbles are mixed in the chemical solution in the inserted cylinder 221.

The injection head 110 is provided with two piston drive mechanisms 130 that are driven independently of each other in order to operate the piston 222 of the mounted syringe assembly 200 corresponding to the position where each syringe assembly 200 is mounted. ing. The piston drive mechanism 130 includes a piston holding mechanism that holds a convex portion formed at the end of the piston 222 and a rod member that moves the piston holding mechanism forward and backward. The syringe assembly 200 attached to the injection head 110 can inject the liquid medicine filled in the syringe 220 into the subject separately or simultaneously by operating the piston 222 by the piston drive mechanism 130. As the piston drive mechanism 130, a known mechanism generally used for this type of injection device can be adopted.

A syringe receiver 120 configured to have a concave inner surface so as to support an outer peripheral surface of the syringe assembly 200 at a distal end portion of the injection head 110, and a syringe holder 140 for fixing the syringe assembly 200 to the injection head 110. Is provided.

The syringe receiver 120 has two recesses 121 for receiving a portion corresponding to the cylinder 221 of the syringe assembly 200, and the two syringe assemblies 200 are respectively in the recesses 121 with the nozzle portion 221b facing the distal end side. Placed.

In addition, the syringe receiver 120 is configured to have translucency so that it can be visually confirmed through the syringe receiver 120 whether or not bubbles are mixed in the chemical solution in the syringe assembly 200 placed in the recess 121. Yes. That is, the presence of bubbles in the chemical solution in the cylinder 221 can be visually observed through the pressure-resistant cover 270 and the syringe receiver 120. Such a syringe receiver 120 can be formed using a transparent resin material such as polycarbonate resin.

In general, a chemical solution is injected into a subject while being heated to about body temperature. However, the temperature of the chemical solution decreases with the passage of time from when the syringe assembly 200 is attached to the injection head 110 to when it is injected into the subject. There are things to do. Therefore, in this embodiment, the syringe receiver 120 incorporates two translucent heaters 125 corresponding to the respective recesses 121 in order to keep the drug solution in the syringe assembly 200 attached to the injection head 110 warm.

The translucent heater 125 may be any heater as long as it does not hinder the translucency of the syringe receiver 120. For example, a transparent substrate and wiring formed in an appropriate pattern on the transparent substrate, A pair of electrodes connected to both ends of the wiring; In order for the translucent heater 125 not to impede the translucency of the syringe receiver 120, it is preferable that the light transmittance in the heat generation region, which is the region where the wiring pattern is formed, be 70% or more. The light transmittance referred to in the present invention is the transmittance of white light.

The transparent substrate may or may not have flexibility, but in this embodiment is formed of a flexible resin film. Thereby, as shown in FIG. 3, the translucent heater 125 can be configured to be curved in accordance with the shape of the concave portion 121 of the syringe receiver 120. By curving the translucent heater 125 in this way, the syringe assembly 200 can be kept warm.

As the wiring, an appropriate wiring used for this type of heater, for example, a wiring made of a transparent conductive film or a wiring made of a metal thin film can be used. Examples of the material constituting the transparent conductive film include ITO (Indium Tin Oxide). Moreover, copper, silver, aluminum, etc. are mentioned as a material which comprises a metal thin film. When the wiring is formed of a metal thin film, the wiring itself does not have optical transparency. Therefore, in order to prevent the translucent heater 125 from hindering the translucency of the syringe receiver 120, a resin film having a light transmittance of 80% or more is used as the transparent substrate, and the wiring width is set to 5 to 100 μm. It is preferable to do. Such a translucent heater 125 can be obtained from U Corporation.

As described above, by configuring the syringe receiver 120 to have translucency, the syringe assembly 200 mounted on the injection head 110 can be changed in the syringe assembly 200 from any direction in the circumferential direction of the syringe assembly 200. It can be visually confirmed without being blocked by the receiver 120. Therefore, regardless of the posture of the injection head 110, it can be visually confirmed whether or not bubbles are mixed in the syringe 220. As a result, the chemical solution is mistakenly detected without noticing the mixing of bubbles. Can be prevented from being injected.

Further, by incorporating the translucent heater 125 in the syringe receiver 120, the syringe receiver 120 is configured to have translucency, but the syringe mounted on the injection head 110 without hindering the translucency. 220 can be kept at a temperature suitable for injection, and the chemical solution can be injected at the kept temperature.

Next, the syringe holder 140 will be described. The syringe holder 140 holds the cover flange 271 of the syringe assembly 200 supported by the syringe receiver 120.

As shown in FIG. 4, the syringe holder 140 has three

shafts

150a, 150b, and 150c, a base member 141, and two flange pressing members 142 that are arranged in parallel at intervals.

The shaft 150 also serves as a part of the frame structure of the injection head 110, and supports the syringe holder 140 and the syringe receiver 120 at the tip. Further, the interval between the shafts 150a to 150c is larger than the diameter of the cover flange 271 which is a portion of the syringe assembly 200 held by the syringe holder 140.

The base member 141 has two flange receiving recesses 141 a that receive the outer peripheral surface of the cover flange 271. The flange receiving recess 141a is a portion formed in an arc shape so that the inner peripheral surface thereof receives the outer peripheral surface of the cover flange 271 and is located between the shafts 150a to 150c.

The two flange pressing members 142 are arc-shaped parts formed so as to surround the cover flange 271 over almost the entire circumference by being combined with the flange receiving recess 141a. Each flange pressing member 142 is pivotable between an open position where the cover flange 271 can be attached and detached and a closed position where the cover flange 271 is held so as to open and close the flange receiving recess 141a. The portion is supported by the two

outer shafts

150a and 150c. An engaging structure that engages with the central shaft 150b is provided at the free end of the flange pressing member 142 in order to hold the flange pressing member 142 in the closed position.

When the syringe assembly 200 is attached to the injection head 110, as shown in FIG. 5, the cover flange 271 is positioned on the flange receiving recess 141a (see FIG. 3) with the flange pressing member 142 in the open position. The syringe assembly 200 is placed on the syringe receiver 120. Thereafter, by rotating the flange pressing member 142, the engaging structure is engaged with the central shaft 150b, and the flange pressing member 142 is held at the closed position as shown in FIG. Thereby, the cover flange 271 is fixed to the syringe holder 140 and the syringe assembly 200 is attached to the injection head 110.

The engagement structure of the flange pressing member 142 can be an arbitrary structure, and in this embodiment, the flange pressing member 142 has a recess 143 and a ball plunger 144 provided on the outer surface of the free end portion of the flange pressing member 142. The recessed portion 143 is formed in a shape that hangs on the outer peripheral surface of the central shaft 150b when the flange pressing member 142 is in the closed position. The ball plunger 144 includes a ball, a casing that holds the ball so that a part of the ball can protrude, and a spring that biases the ball in a direction in which the ball protrudes from the casing, so that the ball protrudes from the recess 143. It is embedded in the flange pressing member 142.

The position of the ball plunger 144 is such that the ball of the ball plunger 144 abuts against the shaft 150b and is pushed into the casing while the flange pressing member 142 rotates from the open position to the closed position. It is preferable that the position be released from. As a result, the flange pressing member 142 can be favorably held at the closed position. Further, a click feeling is obtained when the ball of the ball plunger 144 is released from the shaft 150b, and the operator can easily recognize that the flange pressing member 142 has reached the closed position.

Further, by using the ball plunger 144 in the engagement structure, when the engagement of the flange pressing member 142 in the closed position with the shaft 150b is released, the flange pressing member 142 is simply rotated toward the release position. It's okay. A knob 145 is provided at the free end of the flange pressing member 142 so that the flange pressing member 142 can be easily rotated.

By configuring the syringe holder 140 as described above, the central shaft 150b can be commonly used to hold the two flange pressing members 142 in the closed position. As a result, the structure for holding the two flange pressing members 142 in the closed position can be configured with a small space and a simple mechanism. Further, since the syringe holder 140 holds only the cover flange 271 of the syringe assembly 200, it does not affect the visibility of the state of the chemical solution filled in the syringe 220 at all.

In this embodiment, the syringe assembly 200 including the syringe 220 and the pressure-resistant cover 270 has been described as an example. However, when the syringe 220 has a sufficient pressure resistance, the syringe assembly 200 does not include the pressure cover 270, and the syringe 220 may be directly attached to the injection head 110. In this case, the flange 221 a of the syringe 220 has a shape that can be held by the syringe holder 140. Alternatively, an adapter (not shown) that adapts the flange 221a to the syringe holder 140 may be prepared separately so that the syringe 220 can be attached to the injection head 110 via this adapter. Furthermore, the syringe is not limited to a rodless syringe and can be configured to be compatible with various syringes.

Further, in this embodiment, an example in which the entire syringe receiver 120 is configured to be translucent is shown. However, it is possible to visually check whether or not bubbles are mixed in the chemical solution in the syringe assembly 200. For this purpose, the entire syringe receiver 120 does not need to have translucency, and the syringe receiver 120 only needs to have at least the recess 121 having translucency.

Further, in this embodiment, the CT angio device 300 is used as the fluoroscopic imaging device, and the chemical solution injection device is exemplified as having a configuration suitable for injecting a contrast medium for CT. However, the chemical solution injection device of the present invention is A configuration suitable for injecting a contrast medium for an MRI apparatus or a PET apparatus, which are other types of fluoroscopic imaging apparatuses, may be used.

110 Injection head 120 Syringe receiver 121 Concave 125 Translucent heater 130 Piston drive mechanism 140 Syringe holder 141 Base member 142 Flange pressing member 143 Concave 144 Ball plunger 145

Knob

150a, 150b, 150c Shaft 200 Syringe assembly 220 Syringe 221a Cylinder 221a Flange 221b Nozzle part 222 Piston 270 Pressure-resistant cover 271 Cover flange

Claims

In a chemical liquid injector having an injection head to which a syringe assembly is detachably mounted,
The injection head holds the syringe assembly by holding a syringe receiver having a concave inner surface so as to support an outer peripheral surface of the syringe assembly and a flange formed at a distal end of the syringe assembly. A syringe holder that is fixed to the injection head;
The syringe receiver is translucent to such an extent that at least a portion having the concave inner surface can be visually confirmed through the syringe receiver whether or not bubbles are mixed in the liquid medicine filled in the syringe assembly. A chemical injection device characterized by comprising:
The chemical solution according to claim 1, wherein the syringe receiver includes a translucent heater that keeps the chemical solution in the syringe assembly attached to the injection head and does not impair the translucency of the syringe receiver. Injection device.
The chemical injection device according to claim 2, wherein the translucent heater has flexibility and is curved in accordance with the concave shape of the syringe receiver.
The injection head is configured to mount the two syringe assemblies in parallel;
The flange holder is
Three shafts arranged in parallel with an interval larger than the diameter of the flange;
A base member formed by two arc-shaped flange receiving recesses for receiving the outer peripheral surface of the flange at a position between the shafts;
An engagement structure that is rotatably supported by two outer shafts of the shafts so as to open and close with respect to the flange receiving recesses, and engages with a central shaft of the shafts. Two flange pressing members provided in the section,
The chemical | medical solution injection device of any one of Claim 1 to 3 which has these.
The syringe assembly includes
A syringe having a cylinder and a piston for filling the chemical solution;
A cover member in which a cover flange is formed at the end as the flange into which the syringe is inserted;
The chemical injection device according to any one of claims 1 to 4, comprising: