WO2010101485A3 - A pharmaceutical composition containing celecoxib and a process of the manufacture thereof - Google Patents

A pharmaceutical composition containing celecoxib and a process of the manufacture thereof Download PDF

Info

Publication number
WO2010101485A3
WO2010101485A3 PCT/PL2010/000018 PL2010000018W WO2010101485A3 WO 2010101485 A3 WO2010101485 A3 WO 2010101485A3 PL 2010000018 W PL2010000018 W PL 2010000018W WO 2010101485 A3 WO2010101485 A3 WO 2010101485A3
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical composition
composition containing
manufacture
containing celecoxib
celecoxib
Prior art date
Application number
PCT/PL2010/000018
Other languages
French (fr)
Other versions
WO2010101485A2 (en
Inventor
Rafal Lunio
Jaroslaw Mazgalski
Original Assignee
Zaklady Farmaceutyczne Polpharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zaklady Farmaceutyczne Polpharma Sa filed Critical Zaklady Farmaceutyczne Polpharma Sa
Publication of WO2010101485A2 publication Critical patent/WO2010101485A2/en
Publication of WO2010101485A3 publication Critical patent/WO2010101485A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The subject matter of the invention is a pharmaceutical composition containing celecoxib as the active substance and a pharmaceutically acceptable carrier. The pharmaceutical composition contains a cross-linked polymer. The subject matter of the invention also includes the process of manufacturing of the pharmaceutical composition.
PCT/PL2010/000018 2009-03-06 2010-03-03 A pharmaceutical composition containing celecoxib and a process of the manufacture thereof WO2010101485A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PLP.387415 2009-03-06
PL387415A PL387415A1 (en) 2009-03-06 2009-03-06 Pharmaceutical composition containing celecoxib and method of its manufacturing

Publications (2)

Publication Number Publication Date
WO2010101485A2 WO2010101485A2 (en) 2010-09-10
WO2010101485A3 true WO2010101485A3 (en) 2010-11-04

Family

ID=42668876

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/PL2010/000018 WO2010101485A2 (en) 2009-03-06 2010-03-03 A pharmaceutical composition containing celecoxib and a process of the manufacture thereof

Country Status (2)

Country Link
PL (1) PL387415A1 (en)
WO (1) WO2010101485A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2630051T3 (en) * 2012-08-27 2017-08-17 Cadila Healthcare Limited Pharmaceutical composition of Etoricoxib
CN105343030A (en) * 2015-12-16 2016-02-24 钟柏根 Celecoxib capsule and preparation method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000032189A1 (en) * 1998-11-30 2000-06-08 G. D. Searle & Co. Celecoxib compositions
WO2001045706A1 (en) * 1999-12-22 2001-06-28 Pharmacia Corporation Dual-release compositions of a cyclooxygenase-2- inhibitor
WO2002085336A1 (en) * 2001-04-20 2002-10-31 Ethypharm Orodispersible effervescent tablets
WO2007070843A2 (en) * 2005-12-15 2007-06-21 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for oral administration
WO2009063367A1 (en) * 2007-11-15 2009-05-22 Pfizer Products Inc. Dosage forms comprising celecoxib providing both rapid and sustained pain relief

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000032189A1 (en) * 1998-11-30 2000-06-08 G. D. Searle & Co. Celecoxib compositions
WO2001045706A1 (en) * 1999-12-22 2001-06-28 Pharmacia Corporation Dual-release compositions of a cyclooxygenase-2- inhibitor
WO2002085336A1 (en) * 2001-04-20 2002-10-31 Ethypharm Orodispersible effervescent tablets
WO2007070843A2 (en) * 2005-12-15 2007-06-21 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for oral administration
WO2009063367A1 (en) * 2007-11-15 2009-05-22 Pfizer Products Inc. Dosage forms comprising celecoxib providing both rapid and sustained pain relief

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BABU P S ET AL: "Enhancement of dissolution rate of celecoxib by solid dispersions in superdisintegrants", INDIAN DRUGS, vol. 45, no. 7, July 2008 (2008-07-01), pages 547 - 552, XP009138418, ISSN: 0019-462X *
DIXIT R ET AL: "In vitro and in vivo advantage of celecoxib surface solid dispersion and dosage form development", INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 69, no. 3, 1 February 2007 (2007-02-01), pages 370 - 377, XP009138408, ISSN: 0250-474X *
HE ET AL: "Development of a rapidly dispersing tablet of a poorly wettable compound-formulation DOE and mechanistic study of effect of formulation excipients on wetting of celecoxib", INTERNATIONAL JOURNAL OF PHARMACEUTICS, ELSEVIER BV, NL LNKD- DOI:10.1016/J.IJPHARM.2007.11.045, vol. 353, no. 1-2, 22 January 2008 (2008-01-22), pages 176 - 186, XP022513718, ISSN: 0378-5173 *

Also Published As

Publication number Publication date
WO2010101485A2 (en) 2010-09-10
PL387415A1 (en) 2010-09-13

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