WO2010097799A1 - Pansement pour plaies obtenu par électrofilage - Google Patents

Pansement pour plaies obtenu par électrofilage Download PDF

Info

Publication number
WO2010097799A1
WO2010097799A1 PCT/IL2010/000165 IL2010000165W WO2010097799A1 WO 2010097799 A1 WO2010097799 A1 WO 2010097799A1 IL 2010000165 W IL2010000165 W IL 2010000165W WO 2010097799 A1 WO2010097799 A1 WO 2010097799A1
Authority
WO
WIPO (PCT)
Prior art keywords
dressing
wound
capillary
exudate
fibers
Prior art date
Application number
PCT/IL2010/000165
Other languages
English (en)
Inventor
Alexander Dobson
Original Assignee
Nicast Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicast Ltd. filed Critical Nicast Ltd.
Publication of WO2010097799A1 publication Critical patent/WO2010097799A1/fr

Links

Classifications

    • A61F13/01042—
    • A61F13/05—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/91—Suction aspects of the dressing
    • A61M1/915—Constructional details of the pressure distribution manifold
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/91—Suction aspects of the dressing
    • A61M1/918—Suction aspects of the dressing for multiple suction locations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00365—Plasters use
    • A61F2013/00536—Plasters use for draining or irrigating wounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00855—Plasters pervious to air or vapours
    • A61F2013/00863—Plasters pervious to air or vapours with pores
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/98—Containers specifically adapted for negative pressure wound therapy
    • A61M1/984—Containers specifically adapted for negative pressure wound therapy portable on the body
    • A61M1/985—Containers specifically adapted for negative pressure wound therapy portable on the body the dressing itself forming the collection container

Definitions

  • US patent 7070584 provides a ceramic foam dressing.
  • the capillaries draw liquid through the dressing from the wound.
  • the length of the capillaric pathway is long, and vulnerable to clogging, thereby limiting removal of suppurating liquid from the wound.
  • ceramic dressings are frangible, making the total fluid removal effect unpredictable and in many cases inadequate and again, vulnerable to clogging.
  • the clogged exudate will eventually become a source of serious bacterial contamination.
  • the aforesaid dressing comprises a plurality of capillary-like pores.
  • the dressing is adapted to be removably adhered to the wound in an air-tight way and remove exudate therefrom.
  • the invention is a core purpose of the invention to provide the capillary dressing provided by means of electrospinning.
  • the dressing is characterized by porosity ranged between about 3 and about 50 microns.
  • Another object of the invention is to disclose the capillary dressing made of polymer fibers.
  • the polymer is selected from the group consisting of polyurethane-silicon copolymer, Polyurethanecarbonate, Polycarbonate and any combination thereof.
  • a further object of the invention is to disclose the capillaries characterized by water suction height ranged between about 50 and about 150 mm.
  • a further object of the invention is to disclose the capillaries characterized by protein suction productivity ranged between about 0.05 g-cm ⁇ -min "1 and 0.3 g-cm ⁇ -min "1 .
  • a further object of the invention is to disclose the capillary which is in a fluid communication with a pump providing air rarefaction in a wound area.
  • a further object of the invention is to disclose the step of removing the exudate from the wound further comprising a step of vacuuming a wound area by means of a pump fluidly connected to the dressing.
  • FIG. 1 is a schematic presentation of the experimental measurement of maximum height provided due to capillary water suction.
  • the term 'wound' hereinafter refers to a type of injury in which the skin is torn, cut or punctured (an open wound), or where blunt force trauma causes a contusion
  • dressing refers to an adjunct used by a person for application to a wound in order to promote healing and/or prevent further harm.
  • a dressing is designed to be in direct contact with the wound.
  • exudate' hereinafter refers to any fluid that filters from the circulatory system into lesions or areas of inflammation. Its composition varies but generally includes water and the dissolved solutes of the blood, some or all plasma proteins, white blood cells, platelets and (in the case of local vascular damage) red blood cells.
  • a biocompatible wound dressing is shaped to conform to a wound site.
  • the aforesaid dressing comprises a plurality of capillary-like pores.
  • the dressing is adapted to be removably adhered to the wound in an air-tight manner and remove fresh exudate continuously with little or no blocking.
  • the dressing or at least the part of the dressing which comes into contact with the wound surface is constructed of special electrospun material characterised by a plurality of capillary pores, which are effectively hollow capillary tubes, extending continuously from the surface of the wound (the lower surface of the dressing) to the upper surface of the dressing.
  • the dressing facilitates the removal of fresh exudate, and the aforesaid dressing is characterized by porosity ranged between about 3 and about 50 microns.
  • the capillaries are characterized by water suction height ranged between about 50 and about 150 mm.
  • the capillaries are characterized by protein suction productivity ranged between about 0.05 g-cm ⁇ -min "1 and
  • the capillary dressing is in a fluid communication with a pump providing air rarefaction (suction) over the wound area.
  • the step of providing the dressing further comprises a step of electrospinning polymer fibers.
  • the fibers are selected from the group consisting of polyurethane-silicon copolymer fibers,

Abstract

L'invention concerne un pansement biocompatible pour plaies, dont la forme est conçue pour épouser le site d'une plaie. Le pansement susmentionné comprend des pores faisant fonction de capillaires. Le pansement est conçu pour adhérer de façon amovible à la plaie en étanchéité à l'air et pour évacuer l'exsudat. Le pansement capillaire est obtenu par électrofilage et caractérisé par une porosité comprise entre environ 3 et environ 50 microns.
PCT/IL2010/000165 2009-02-25 2010-02-25 Pansement pour plaies obtenu par électrofilage WO2010097799A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15518309P 2009-02-25 2009-02-25
US61/155,183 2009-02-25

Publications (1)

Publication Number Publication Date
WO2010097799A1 true WO2010097799A1 (fr) 2010-09-02

Family

ID=42132266

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2010/000165 WO2010097799A1 (fr) 2009-02-25 2010-02-25 Pansement pour plaies obtenu par électrofilage

Country Status (1)

Country Link
WO (1) WO2010097799A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060084340A1 (en) * 2004-04-19 2006-04-20 The Procter & Gamble Company Fibers, nonwovens and articles containing nanofibers produced from high glass transition temperature polymers
US20060094320A1 (en) * 2004-11-02 2006-05-04 Kimberly-Clark Worldwide, Inc. Gradient nanofiber materials and methods for making same
US7070584B2 (en) 2001-02-20 2006-07-04 Kci Licensing, Inc. Biocompatible wound dressing
WO2007060433A1 (fr) * 2005-11-25 2007-05-31 Smith & Nephew, Plc Pansement fibreux
US20070225631A1 (en) * 2002-10-04 2007-09-27 Bowlin Gary L Sealants for Skin and Other Tissues
US20080275409A1 (en) * 2007-05-01 2008-11-06 The Brigham And Women's Hospital, Inc. Wound healing device

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7070584B2 (en) 2001-02-20 2006-07-04 Kci Licensing, Inc. Biocompatible wound dressing
US20070225631A1 (en) * 2002-10-04 2007-09-27 Bowlin Gary L Sealants for Skin and Other Tissues
US20060084340A1 (en) * 2004-04-19 2006-04-20 The Procter & Gamble Company Fibers, nonwovens and articles containing nanofibers produced from high glass transition temperature polymers
US20060094320A1 (en) * 2004-11-02 2006-05-04 Kimberly-Clark Worldwide, Inc. Gradient nanofiber materials and methods for making same
WO2007060433A1 (fr) * 2005-11-25 2007-05-31 Smith & Nephew, Plc Pansement fibreux
US20080275409A1 (en) * 2007-05-01 2008-11-06 The Brigham And Women's Hospital, Inc. Wound healing device

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