WO2010085167A1

WO2010085167A1 - Method for correcting vision disorders

Info

Publication number: WO2010085167A1
Application number: PCT/RU2009/000098
Authority: WO
Inventors: Татьяна Прохоровна ТЕТЕРИНА; Анастасия Сергеевна ГОЛУБЕВА
Original assignee: Teterina Tatyana Prokhorovna; Golubeva Anastasia Sergeevna
Priority date: 2009-01-26
Filing date: 2009-03-02
Publication date: 2010-07-29
Also published as: RU2401672C1; RU2009102293A

Abstract

The invention relates to medicine, more specifically to a method for correcting vision disorders. The basis of the method is that vision disorders are corrected by the action of the visible spectrum on the eye; furthermore, the action is performed on the same eye using a series of pulses of light radiation of different wavelengths in the visible light range. Moreover, the method for correcting vision disorders is carried out by acting on each of the patient's eyes with a series of pulses of light radiation in the visible light range; each eye is exposed to the action of the visible spectrum at different wavelengths; furthermore, when a subsequent series of pulses is supplied, the wavelength of one colour is substituted by the wavelength of the opposite colour.

Description

The method of correction of visual impairment

The technical field The invention relates to the field of medicine, namely to ophthalmology.

BACKGROUND OF THE INVENTION A method is known for correcting visual disturbances in dysbinocular amblyopia by stimulating the retina with a white light of a light bulb using a large reflex-free ophthalmoscope (BWO) (US .Nb 511079, A61F9 / 00, 1976; Avetisov ES, Friendly Eye Conservation, M, " Medicine. "1977, p. 235). However, this method is intended for exposure to light in only one eye, which does not allow its use to affect both eyes simultaneously or alternately with bilateral weak vision, impaired binocular vision, strabismus, refractive errors and other organ pathologies. In addition, this method lengthens the duration of treatment, is not effective enough and unsuitable for the treatment of young children (2-3 years).

Closer in the aggregate of essential features and adopted as a prototype is a method for improving visual functions by exposing both eyes to light in the visible region (RU N "2071301, A61F9 / 00 01/10/97).

However, this method has the following disadvantages. When each of the patient's eyes is exposed to a series of pulses of light radiation in the range of visible light, they are exposed to light of the same wavelength of the spectrum. This method does not provide the simultaneous effect of the opposing wavelengths on the same eye.

Disclosure of invention

The technical result is an increase in efficiency and a reduction in treatment time, including for the treatment of young children.

This result is achieved due to the fact that in the method of correcting visual disturbances by exposing each of the patient's eyes with a series of pulses of light radiation, the effect on each eye produce different wavelengths of the spectrum of visible light. Moreover, when applying the next series of pulses, the wavelength corresponding to the given color radiation is changed by the wavelength corresponding to the opponent color. This stimulation approach provides the response of the on- and ofFF-zones of the receptive fields (RP) of the ganglion cells of the retina, external cranks and the primary visual cortex located in the posterior sections of the cerebral cortex. In this case, mutual antagonism of the central and peripheral zones of the RP occurs: when exposed to the green stimulus, the periphery (off zone) is excited and the center (op zone) of the RP is decelerated, and when the red stimulus is activated, the center (op zone) is excited and inhibition (off -zones) RP.

The specified result is also achieved due to the fact that they change the wavelength in a series of pulses. Pulses are applied in the frequency range 0.06-1 Hz in one series and 0.2-10 Hz in another series. The best embodiment of the invention

According to the present invention, a new method for correcting visual impairment is considered, which consists in alternating pulsed color exposure to each of the patient's eyes with a series of pulses of light radiation in the range of visible light. In this case, an alternating effect on each eye is performed with a different wavelength, and when the next series of pulses is applied, the wavelength corresponding to the given color radiation is changed to the wavelength corresponding to the opponent color. The method is characterized by the fact that corrections change the wavelength in a series of pulses and the pulses are applied in the frequency range from 0.06-1 Hz in one series and up to 0.2-10 Hz in another series.

In nature, there is a law of color mixing, which consists in the fact that for every color there is such a different color, from mixing with which an achromatic color is formed: white or black. These two colors are called complementary or opposed, or antagonistic (Schiffman X. “Sensation and Perception”, St. Petersburg, 2003, pp. 212-229, Chapter 5. “Color vision”). White light is a mixture of radiation having different wavelengths. A wavelength range of 400 to 700 nm is an integral part of the spectrum produced by prisms and diffraction gratings. The following wavelengths correspond to spectral colors:

In practice, the human eye is able to distinguish between colors of radiation with a wavelength of 396 nm (deep purple) to 760 nm (extreme red). Under normal conditions, radiation with different wavelengths gets into the eye. The color sensation arising in this case depends on the ability to see one resulting color, determined according to the laws of optical color shift. These laws were derived by Grassman, and they were experimentally confirmed in the works of Maxwell et al.

There are receptive fields in the retina of the eye, the region of the external cranked bodies, and the visual cortex of the brain, which are spatially separated by the op-center (+) and off-periphery (-) by antagonistic zones of excitation and inhibition. Under the influence of a color stimulus on the eye, there is an antagonism of their reactions to opponent colors: on red, excitation of the on-center (+) and inhibition of the off-periphery (-) of the receptive field, and when exposed to a green stimulus, excitation of the periphery and inhibition of the center of the receptive field.

Thus, two antagonistic colors in the retina of the eye and the brain interact with each other according to the law of excitation and inhibition, which ensures the normal functional activity of the visual system and the brain.

Violations of the antagonistic interaction of these zones of receptive fields is one of the causes of visual disturbances. The table shows the results of color correction with alternating exposure to the eye of each pair of opponent colors with an interval of 1-2 s for 5-6 s; session - within 5-10 minutes

The combination of antagonistic (opponent) colors modulates and balances interhemispheric relationships, the sympathetic and parasympathetic innervations of the autonomic nervous system, which helps to improve and normalize the visual functions and psychosomatic state of patients (see the table where the color designation is: K - red, Op - orange, F - yellow, 3 - green, G - cyan, C - blue, P - magenta).

Table

Examples of the method.

Example 1. Patient P., 76 years old. Diagnosis: initial cataract of both eyes, condition after thrombosis of the lower temporal branch of the central retinal vein, retinoschisis and central chorioretinal dystrophy of the left eye.

The visual acuity of the right eye is 0.7, optical glasses are not corrected, the left eye is 0.04, corr. - 2.0D = 0.1. A color correction course was carried out in accordance with this method using the apparatus of Teterina T.P. (RU Ns 2230534). In the device Teterina TJI. set the operation mode of the device depending on the pathology. An electronic circuit, for example, allows you to form the following radiation modes:

- alternating effects on the eyes with a given period of soreness;

- periodic exposure to one of the eyes and continuous exposure to the other; - any of the above modes with radiation modulation.

In this case, it is possible to affect both eyes with the same or different wavelengths: 660 nm (red color). 600 nm (orange), 567 nm (green), 470 nm (blue). The timer ensures that the device turns off after a certain time (for example, 8.5 minutes). When the device is operating in a light-diffusing reflector, pulsating light emission from LEDs occurs. Light passes through the openings of the opaque screen, as a result of which the patient observes the pulsation of light stimuli. The patient, in the process of color retinal stimulation through an opaque screen placed on a light-scattering reflector in glasses, observes the pulsation of light stimuli corresponding to the screen openings, which testified to the response of visual neurons of the retina of the eye and brain to color stimuli. After 10 sessions of color correction according to the proposed method, the visual acuity of the right eye is 1.0; left eye 0.1, corr. - 2.5 D = 0.2.

Thus, the patient after color grading normalized visual acuity in the right eye, which indicates the reversibility of the initial stage of cataracts. Visual acuity in the left eye improved only by 10%, which is associated with gross degenerative changes in the retina after a central retinal vein thrombosis.

Example 2. Patient C, 70 years old. Diagnosis: initial cataract, myopia, retinal vascular angiosclerosis in both eyes. Visual acuity of the right eye - 0.02, with the correspondent - 3.0 D = 01; left eye -

0.02, correspondent - 4.5 D - 0.1. The font on the table for near does not see.

After 10 sessions of color correction according to the proposed method using the apparatus Teterina TP visual acuity into the distance of the right eye - 0.1, corr .. -

3.0 D = 0.8; left eye - 0.08, corr. - 4.5D = 0.8. Visual acuity of the right and left eye near without correction = 0.6 (freely reads the font .Ns 5 according to the table for close).

Thus, according to the proposed method, this patient achieved an increase in visual acuity in the distance by 70%, and near - by 60% and the progression of cataracts was stopped. Example 3. Patient L., 66 years old. At the age of 63, a diagnosis was made of glaucoma in both eyes. A laser antiglaucomatous operation was performed on the right eye.

During the examination, the diagnosis was established: open-angle compensated glaucoma of the far advanced stage of the right eye and the developed stage of the left eye, moderate myopia and initial cataract of both eyes.

Visual acuity without correction of the right eye was equal to the movement of the shadow in the face, the left eye - 0.02, correl.-5.0 D - 0.06 and 0.6, respectively. The right eye without correction did not distinguish the font on the table for near, the left eye read the font JСh 7 (visual acuity = 0.4). The intraocular pressure of both eyes is normal. Clouding of the cortical layers of the lens. Fundus: optic disc of the right eye with a grayish tint, excavation of the disc, on the upper edge of it is a myopic cone. The optic disc of the left eye is pale, with a myopic cone along its upper edge. The retinal veins of both eyes are dilated, the arteries are narrowed. Borders of visual fields: with the right eye, on the nasal side, the object did not distinguish (complete loss of the nasal half of the visual field), on the temporal side, the boundaries of the visual field were within 60 ° (narrowed by 20 °).

After a course of color correction according to the proposed method using the apparatus Teterina T.P. visual acuity in the distance with the correction of the right eye = 0.3; left eye = 0.9. Visual acuity near without correction of the right eye =

0.3 (according to the table near it reads the font JVe 8), left eye = 0.6 (reads the font .N2 5). The clouding of the lens in both eyes decreased.

The boundaries of the field of view of the right eye from the nasal side are 10 °, the upper nasal is 30 °, the lower nasal and lower are 0 °, from the temporal side is 75 °, the boundaries of the field of vision of the left eye have expanded to normal.

Fundus of the eye: the optic disc of the left eye turned pink.

Thus, after color grading, the visual functions in this patient improved significantly in both eyes. According to the state of the boundaries of the visual fields on the left eye, glaucoma from the second stage moved to the first stage. The progression of the glaucomatous process was suspended in the right eye, which could lead to complete loss of vision, i.e. incurable blindness.

Example 4. Patient C, 66 years old. Diagnosis: Terminal glaucoma of the right eye, open-angle glaucoma of the 1st stage, compensated under the myotics, initial cataract of the left eye.

Visual acuity of the right eye - 0 (zero); left eye - 0.03, corr. - 6.0 D = 0.2; the boundaries of the field of view are within normal limits. Intraocular pressure is within normal limits (22 mmHg).

Conducted 7 color grading sessions according to the proposed method using the apparatus Teterina T.P. Visual acuity of the right eye - 0 (zero); left eye - 0.03, corr. - 6.0 D - 0.5.

Thus, in this patient, according to the state of initial visual acuity (0.2), a cataract extraction operation was expected on a single sighted eye and high myopia, in which complications often fraught with loss of vision were often observed. As a result of color correction by the proposed method, the progression of cataracts was stopped and an improvement in visual acuity by 30% was achieved due to the reversibility of cataracts in the initial stage. Example 5. Patient H., 67 years old. Diagnosis: almost terminal subcompensated glaucoma of the right eye and far-reaching subcompensated glaucoma of the left eye, glaucomatous atrophy of the optic nerve in both eyes.

Visual acuity of the right eye = counting fingers in the face is eccentric; left eye - 0.2, not corrected by glass. The boundaries of the visual field on the best (left) eye from the nose are 10 °, from the temporal side - 65 °, above - 15 °, below 10 ° (in total - 100 °, and normal - 530 °); on the worst (right) eye from the temporal side - 40 °, and on the remaining meridians - 0 °. Intraocular pressure was elevated and was within 28-29 mm Hg. The course of color correction by the proposed method using the apparatus Teterina T.P. within 10 days.

Visual acuity in the distance of the right eye = counting fingers in the face eccentrically at a distance of 50 cm; left eye = 0.4, corr. + 1.5D = 0.5.

The boundaries of the field of view expanded on the better seeing (left) eye from the nasal side to 25 °, from above to 30 °, from the temporal side to 75 °, from below to 25 ° from the upper temporal and lower temporal sides to 40 ° . The total boundaries of the field of view were 235 °.

On the worse seeing (right) eye, objective vision appeared within 0.01. The boundaries of the field of view expanded from the temporal side to 65 °, from the upper temporal to 25 °, from the lower temporal to 25 °, and from above the nasal /

9 sides of the border of the field of view - 0 °. The total boundaries of the field of view were 115 °. Intraocular pressure returned to normal in both eyes.

Thus, in this patient, due to the glaucomatous process, the initial visual functions (visual acuity and visual field boundaries) of both eyes were on the verge of complete blindness, especially on the right eye. As a result of the course of color correction by the proposed method, the further progression of glaucoma is suspended. On the better seeing (left) eye, an improvement in visual acuity by 30% and an extension of the boundaries of the visual fields by 140 ° were achieved. On the worse seeing (right) eye, objective vision appeared within 0.01 and the boundaries of the visual field expanded by 75 °.

Example 6. Patient D., 49 years old. Diagnosis: presbyopia of both eyes. Visual acuity into the distance of the right and left eye without correction 1.0; near - 0.3, corr. + 1.5 D = 0.5. Conducted 7 color grading sessions according to the proposed method using the apparatus Teterina T.P.

Visual acuity of the right and left eye near improved by 40% and amounted to 0.7 without correction. On the table for near I read the font Jfe 4, which corresponds to visual acuity near 0.7. Thus, in this patient, after color grading according to the proposed method, visual acuity near was normalized and, therefore, does not need glasses for visual work at close range. Along with this, the process of further aging of vision and the progression of senile hyperopia were suspended, and the general state of health improved.

Example 7. Patient X., 62 years old. Diagnosis: anisometropia, refractive amblyopia and hyperopia of a high degree of the left eye (since childhood), initial cataract of both eyes.

Visual acuity into the distance of the right eye is 0.6, the glasses are not corrected, the left eye = 0.03, corr. + 5.0 D = 0.2. Visual acuity of the right eye near without correction 0.2, corr. + 2.0D = 0.5; left eye corr. + 8.0 D = 0.2. Conducted 1 course (10 sessions) of color correction by the proposed method using Teterina T.P. Visual acuity in the distance of the right eye of 0.7, with corr. + l, 0D = 1.0, left eye 0.2, correl .. + 6.0D = 0.7. Visual acuity near the right eye without correction - 0.5, corr. + 4.5D = 0.7; left eye corr. + 6.5D = 0.5.

Thus, in this patient, despite his advanced age, after color correction according to the proposed method, a significant (35%) improvement in visual acuity (from 0.2 to 0.7 with correction) and a 1.5 diopter reduction in the degree of high farsightedness by to the amblyopic eye. In the best eye, visual acuity normalized with correction, which indicates a reversible process of the initial stage of cataracts.

Example 8. Patient U., 65 years old. Diagnosis: immature cataract of the right eye and left eye artifact. A month ago, an operation was performed on the left eye for cataract extraction with implantation of an artificial lens.

Visual acuity in the distance of the right eye = 0.02, the glasses are not corrected; left eye - 0.2, not corrected by glass. Near the right eye does not see, the visual acuity of the left eye is 0.1, the glasses are not corrected.

Conducted 2 courses of 10 color grading sessions according to the proposed method using the apparatus Teterina TJl.

Visual acuity in the distance of the right eye is 0.05, the glasses are not corrected; left eye - 0.2, with corr. - 3.0D = 0.5. Visual acuity near the right eye 0; left eye without correction = 0.5.

Thus, in this patient on the operated eye for cataracts after color correction according to the proposed method, visual acuity in the distance improved by 0.3 (from 0.2 to 0.5), and close by 0.4 (from 0, 1 to 0 ,5).

Example 9 .. Patient C, 66 years old. Diagnosis: artifact, macular degeneration and atrophy of the optic nerve of the right eye; cataract of the initial stage and weak myopia of the left eye. At the age of 60, a cataract extraction with implantation of an artificial lens and laser coagulation for macular degeneration were performed for cataracts of the right eye ..

Visual acuity of the right eye = 0.02, the glasses are not corrected; left eye = 0.2, corr. - 1.5D = 1.0. On the table near the right eye the font does not see, and the left eye reads the font JVs 9 without correction, which corresponds to a visual acuity of 0.2. Ophthalmoscopically in the macular region of the right eye, foci of lasercoagulation and optic atrophy are determined. On the left eye, opacities in the anterior cortical layers of the lens are determined. The reflex is pink. With a narrow pupil, details of the fundus under the fleur are visible.

After the course (10 sessions), color grading according to the proposed method using the apparatus Teterina TP visual acuity in the distance of the right eye = 0.2, the glasses are not corrected. Visual acuity of the left eye without correction = 1.0. On the table for near the left eye reads the font .NЬ 4, which corresponds to a visual acuity of 0.7. The environments of the left eye are transparent, the clouding of the lens has disappeared. With a narrow pupil, details of the fundus are clearly visible. No pathological changes were detected.

Thus, in this patient, despite gross changes in the retina and optic nerve in the operated (right) eye, after a course of color correction by the proposed method, it was possible to improve vision from 0.02 to 0.2. On the best (left eye) visual acuity was restored to normal values (1.0 without correction), which indicates a reversible cataract process in the initial stage due to color correction. Example 10. Patient O., 54 years old. Diagnosis: postcontusional retinal macular degeneration (edematous form) of the left eye. Three months ago there was a bruise of the left eye with a stone. I was in hospital treatment, where medication was carried out (injections under the conjunctiva and retrobulbar). The visual acuity of the right eye is 1.0, the left eye is 0.3, the glasses are not corrected. Conducted 1 course (10 sessions) of color correction by the proposed method using the apparatus Teterina TP

Visual acuity into the distance of the right eye is 1.0, the left eye is 0.7 _” corr .. + 0.5D = 0.8. Visual acuity near the right eye without correction = 0.5, corr. + 4.5 D = 0.7; left eye corr. + 6.5 D = 0.5.

Thus, in this patient, a positive result on an eye with macular degeneration that is not amenable to medical treatment indicates a high efficiency of color correction according to the proposed method. Example 11. Patient T., 13 years old. Diagnosis: Mild myopia, progressive, in both eyes.

Visual acuity of the right and left eye - 0.6, corr. - 1.5D = 1.0. Refraction - myopia at 1.5 D.

After the course (10 sessions) of color correction according to the proposed method using the apparatus of Teterina T. P. the visual acuity of both eyes returned to normal and was 1.0 without correction. The degree of myopia decreased by l, 0D and amounted to 0.5 D.

Thus, a positive result in this patient with initial myopia indicates that the proposed method can be a prevention of school myopia and its progression.

Example 12. Patient K., 67 years old. Diagnosis: initial cataract of both eyes. Visual acuity into the distance of the right and left eye = 0.6, and near without correction = 0.1.

After a course (10 sessions) of color correction according to the proposed method using the Teterina T. P apparatus, visual acuity in the distance of both eyes returned to normal and equaled 1.0 without correction, and near it improved from 0.1 to 0.6.

Thus, a positive result obtained from this patient indicates that the proposed method can be a prevention of cataract development and its progression. Example 13. Patient P., 48 years old. Diagnosis: presbyopia of both eyes. Visual acuity of the right and left eyes into the distance = 1.0, and on the table for near the font does not distinguish. Has glasses for near + 2.0D.

. After a course (10 sessions) of color correction according to the proposed method using the Teterina T. P apparatus, the visual acuity of both eyes in the distance was 1.0 without correction, and near it improved from 0 to 0.6 without correction.

Therefore, a positive result in this patient indicates that color correction according to the proposed method can be a prevention of vision aging and its progression.

Example 14. Patient P., 26 years old. Diagnosis: atrophy of the optic nerve in both eyes.

From the anamnesis it was found that after severe neuropsychic stress the patient developed pain in the right orbit, aggravated by the movement of the eyeballs. After a week, the vision of the right eye sharply decreased to the level of shadow movement in the face and color perception was impaired. After inpatient drug treatment for 7 days, visual acuity and color perception returned to normal. A month later, vision on the same eye decreased again to the level of shadow movement in the face. After repeated inpatient drug treatment for 7 days, vision was normal. A month later, for the third time, the vision of the right eye again decreased to the level of shadow movement in the face. However, the next inpatient drug treatment did not improve vision.

A month later, pain in the orbit and a decrease in the vision of the left eye to the level of 0.02 appeared. The peripheral boundaries of the visual fields of both eyes were within normal limits, but absolute central scotomas were revealed: on the right and left eye, within 35-40 °. On the fundus was diagnosed with atrophy of the optic nerve in both eyes.

After the first course (7 sessions), the visual acuity of the right eye improved to 0.01, the left eye - to 0.05, vision correction with glasses did not improve. The size of the absolute central cattle decreased by 10-15 °. After a second course (7 sessions), the visual acuity of the right eye improved to 0.02, and the left eye - up to 0.2 with correction. On the right eye, the absolute central scotoma decreased in size by another 10 °, and on the left eye a relative paracentral scotoma was formed in the upper temporal zone from the center.

After the third course (7 sessions), the visual acuity of the right eye improved to 0.04, with corr. - 2.0D = 0.1; left eye = 0.4, corr. - 2.0D = 0.9. There is no color sensation in the right eye; it has improved significantly in the left eye. The peripheral boundaries of the visual fields are normal. In the right eye, the absolute scotoma turned into relative scotoma, its size decreased, and in the left eye, the relative scotoma disappeared. Fundus: optic nerve discs of both eyes are white, arteries are narrowed.

The above example indicates that the proposed method is highly effective in the treatment of unsuitable drug therapy of optic atrophy due to transferred recurrent retrobulbar neuritis.

Thus, the proposed method provides an increase in the effectiveness of visual functions in patients with ophthalmopathology: amblyopia of various origins (dysbinocular and refractive), presbyopia, refractive errors (myopia of hyperopia, astigmatism), cataracts of the initial stage, glaucoma, pathology of the retina and optic nerve.

Industrial applicability

The present invention is industrially applicable, used in the practice of the Center of color therapy of Dr. Teterina "TETTA", Moscow.

Claims

Claim

1. The method of correction of visual disturbances, which consists in a pulsed color alternating effect on each of the patient's eyes with a series of pulses of light radiation in the visible light range, characterized in that the alternating effect on each eye is produced with a different wavelength, and when the next series of pulses is applied, the length is changed waves corresponding to a given color radiation, at a wavelength corresponding to a random color.

2. A method for correcting visual impairment according to claim 1, characterized in that the wavelength is changed in a series of pulses.

3. A method for correcting visual impairment according to claim 1, characterized in that the pulses are applied in the frequency range from 0.06-1 Hz in one series to 0.2 ÷ 10 Hz in another series.