WO2010083294A3 - Diagnostic et traitement de l'ostéoporose - Google Patents

Diagnostic et traitement de l'ostéoporose Download PDF

Info

Publication number
WO2010083294A3
WO2010083294A3 PCT/US2010/021022 US2010021022W WO2010083294A3 WO 2010083294 A3 WO2010083294 A3 WO 2010083294A3 US 2010021022 W US2010021022 W US 2010021022W WO 2010083294 A3 WO2010083294 A3 WO 2010083294A3
Authority
WO
WIPO (PCT)
Prior art keywords
osteoporosis
therapeutics
diagnostics
haplotype
snp
Prior art date
Application number
PCT/US2010/021022
Other languages
English (en)
Other versions
WO2010083294A2 (fr
Inventor
Nazneen Aziz
Venkateswarlu Kondragunta
Xiaodong Wu
Original Assignee
Interleukin Genetics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Interleukin Genetics, Inc. filed Critical Interleukin Genetics, Inc.
Publication of WO2010083294A2 publication Critical patent/WO2010083294A2/fr
Publication of WO2010083294A3 publication Critical patent/WO2010083294A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La présente invention concerne un diagnostic et un traitement de l'ostéoporose mettant en œuvre une identification de l'haplotype d'IL-1 et du modèle de génotype des sujets.
PCT/US2010/021022 2009-01-16 2010-01-14 Diagnostic et traitement de l'ostéoporose WO2010083294A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14540309P 2009-01-16 2009-01-16
US61/145,403 2009-01-16

Publications (2)

Publication Number Publication Date
WO2010083294A2 WO2010083294A2 (fr) 2010-07-22
WO2010083294A3 true WO2010083294A3 (fr) 2011-02-24

Family

ID=42335185

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/021022 WO2010083294A2 (fr) 2009-01-16 2010-01-14 Diagnostic et traitement de l'ostéoporose

Country Status (1)

Country Link
WO (1) WO2010083294A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201314131D0 (en) * 2013-08-07 2013-09-18 Equine Genetics Res Ltd Predictive Method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005013809A2 (fr) * 2003-08-08 2005-02-17 Interleukin Genetics, Inc. Diagnostic et therapeutique pour l'osteoporose
US20070264645A1 (en) * 2002-01-25 2007-11-15 Kenneth Kornman IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes
WO2008010083A2 (fr) * 2006-07-12 2008-01-24 Progenika Biopharma S.A. Procédé diagnostique

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070264645A1 (en) * 2002-01-25 2007-11-15 Kenneth Kornman IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes
WO2005013809A2 (fr) * 2003-08-08 2005-02-17 Interleukin Genetics, Inc. Diagnostic et therapeutique pour l'osteoporose
WO2008010083A2 (fr) * 2006-07-12 2008-01-24 Progenika Biopharma S.A. Procédé diagnostique

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
"Abstracts of Eighth International Symposium on Osteoporosis: Translating Research into Clinical Practice", OSTEOPOROSIS INTERNATIONAL ; WITH OTHER METABOLIC BONE DISEASES, SPRINGER-VERLAG, LO, vol. 20, no. 2, 17 March 2009 (2009-03-17), pages 191 - 229, XP019701491, ISSN: 1433-2965 *
CHEN ET AL: "Tumor necrosis factor alpha, CYP 17, urokinase, and interleukin 10 gene polymorphisms in postmenopausal women: correlation to bone mineral density and susceptibility to osteoporosis", EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVEBIOLOGY, EXCERPTA MEDICA, AMSTERDAM, NL LNKD- DOI:10.1016/J.EJOGRB.2005.02.003, vol. 122, no. 1, 1 September 2005 (2005-09-01), pages 73 - 78, XP005067190, ISSN: 0301-2115 *
GÜR ALI ET AL: "Possible pathogenetic role of new cytokines in postmenopausal osteoporosis and changes during calcitonin plus calcium therapy.", RHEUMATOLOGY INTERNATIONAL SEP 2002 LNKD- PUBMED:12215865, vol. 22, no. 5, September 2002 (2002-09-01), pages 194 - 198, XP002594131, ISSN: 0172-8172 *
PARK BYUNG LAE ET AL: "Association of interleukin 10 haplotype with low bone mineral density in Korean postmenopausal women", JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY, vol. 37, no. 6, 30 November 2004 (2004-11-30), pages 691 - 699, XP002594126, ISSN: 1225-8687 *

Also Published As

Publication number Publication date
WO2010083294A2 (fr) 2010-07-22

Similar Documents

Publication Publication Date Title
EP2498620A4 (fr) Concentrés et isolats de protéines, et procédés de confection de ceux-ci
FR2898073B3 (fr) Jante
NL2003614A (en) Heat-treated flour.
AU317159S (en) Tire (XB02N)
AU317310S (en) Tire (XBDRS)
BRPI0823164A2 (pt) Pneu, e, conjunto.
HK1171082A1 (en) Carcinoma diagnosis and treatments, based on odci genotype odc1
SMT201500064B (it) Trattamento antipsicotico basato su genotipo snp drd2 o ankk1
WO2011044458A8 (fr) Compositions et méthodes de diagnostic de maladies et de troubles associés au génome
EP2187727A4 (fr) Génotypes de blé résistants au glyphosate
EP1990218A4 (fr) Pneu À roulage À plat
EP2246347A4 (fr) Dérivés de dicycloazaalcane, leurs procédés de préparation et utilisations médicales
WO2010083294A3 (fr) Diagnostic et traitement de l'ostéoporose
Johnson Feminist geography
EP2238146A4 (fr) Polypeptides d'hémagglutinine, réactifs, et procédés s'y rapportant
WO2007127309A3 (fr) Procede de synthese d'acide 3-isobutylglutarique
CN301071626S (zh) 客车(eq6750p3g)
Turner Reading Paul. By Michael J. Gorman
AU2009100217A4 (en) Tyre Cover I.D.
WO2011118968A3 (fr) Polymorphisme mononucléotidique pour diagnostiquer la récurrence d'un carcinome hépatocellulaire
GB0803805D0 (en) Assigned seating based on social matching
WO2011049956A3 (fr) Gènes associés à la toxicité, variants génétiques, et leur utilisation
GB0705259D0 (en) Tyre 106A
CN300775451S (zh) 公交车车身(玫瑰红莲花)
AU310191S (en) Rim

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 10700469

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 10700469

Country of ref document: EP

Kind code of ref document: A2