WO2010070637A3 - Procédé permettant de distinguer les tumeurs des surrénales entre elles - Google Patents

Procédé permettant de distinguer les tumeurs des surrénales entre elles Download PDF

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Publication number
WO2010070637A3
WO2010070637A3 PCT/IL2009/001181 IL2009001181W WO2010070637A3 WO 2010070637 A3 WO2010070637 A3 WO 2010070637A3 IL 2009001181 W IL2009001181 W IL 2009001181W WO 2010070637 A3 WO2010070637 A3 WO 2010070637A3
Authority
WO
WIPO (PCT)
Prior art keywords
distinguishing
adrenal tumors
nucleic acid
acid sequences
adrenal
Prior art date
Application number
PCT/IL2009/001181
Other languages
English (en)
Other versions
WO2010070637A2 (fr
Inventor
Yael Spector
Meora Feinmesser
Original Assignee
Rosetta Genomics Ltd.
Mor Research Applications
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rosetta Genomics Ltd., Mor Research Applications filed Critical Rosetta Genomics Ltd.
Publication of WO2010070637A2 publication Critical patent/WO2010070637A2/fr
Publication of WO2010070637A3 publication Critical patent/WO2010070637A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Abstract

Cette invention concerne des séquences d'acides nucléiques qui sont utilisées pour identifier, classer et diagnostiquer des types spécifiques de tumeurs des surrénales. Les séquences d'acides nucléiques selon l'invention peuvent également être utilisées pour évaluer un sujet d'après le profil d'expression d'un échantillon biologique.
PCT/IL2009/001181 2008-12-15 2009-12-13 Procédé permettant de distinguer les tumeurs des surrénales entre elles WO2010070637A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12242208P 2008-12-15 2008-12-15
US61/122,422 2008-12-15

Publications (2)

Publication Number Publication Date
WO2010070637A2 WO2010070637A2 (fr) 2010-06-24
WO2010070637A3 true WO2010070637A3 (fr) 2010-08-12

Family

ID=42269174

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2009/001181 WO2010070637A2 (fr) 2008-12-15 2009-12-13 Procédé permettant de distinguer les tumeurs des surrénales entre elles

Country Status (1)

Country Link
WO (1) WO2010070637A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9150926B2 (en) 2010-12-06 2015-10-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Diagnosis and treatment of adrenocortical tumors using human microRNA-483
US9428813B2 (en) 2012-03-26 2016-08-30 The United States Of America, As Represented By The Secretary, Dept. Of Health & Human Services DNA methylation analysis for the diagnosis, prognosis and treatment of adrenal neoplasms
EP2653558B1 (fr) 2012-04-18 2015-10-07 Roche Diagniostics GmbH Procédé de détection de cibles d'acide nucléique à l'aide d'un classificateur statistique

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070161004A1 (en) * 2004-05-28 2007-07-12 David Brown Methods and compositions involving microRNA
WO2008104985A2 (fr) * 2007-03-01 2008-09-04 Rosetta Genomics Ltd. Procédés pour distinguer un carcinome squameux du poumon d'autres cancers du poumon à non-petites cellules
US20080261908A1 (en) * 2005-08-01 2008-10-23 The Ohio State University MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of breast cancer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070161004A1 (en) * 2004-05-28 2007-07-12 David Brown Methods and compositions involving microRNA
US20080261908A1 (en) * 2005-08-01 2008-10-23 The Ohio State University MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of breast cancer
WO2008104985A2 (fr) * 2007-03-01 2008-09-04 Rosetta Genomics Ltd. Procédés pour distinguer un carcinome squameux du poumon d'autres cancers du poumon à non-petites cellules

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BOTTONI, A. ET AL.: "Identification of Differentially Expressed MicroRNAs by Microarray: A Possible Role for MicroRNA Genes in Pituitary Adenomas.", JOURNAL OF CELLULAR PHSIOLOGY., vol. 210, no. 2, February 2007 (2007-02-01), pages 370 - 377 *
LADEIRO, Y. ET AL.: "MicroRNA Profiling in Hepatocellular Tumors Is Associated with Clinical Features and Oncogene/Tumor Suppressor Gene Mutations.", HEPATOLOGY., vol. 47, no. 6, June 2008 (2008-06-01), pages 1955 - 1963 *
WEBER, F. ET AL.: "A Limited Set of Human MicroRNA Is Deregulated in Follicular Thyroid Carcinoma.", THE JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, vol. 91, no. 9, September 2006 (2006-09-01), pages 3584 - 3591 *

Also Published As

Publication number Publication date
WO2010070637A2 (fr) 2010-06-24

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