WO2010060934A3 - Protéines cnnm et utilisations de celles-ci - Google Patents

Protéines cnnm et utilisations de celles-ci Download PDF

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Publication number
WO2010060934A3
WO2010060934A3 PCT/EP2009/065848 EP2009065848W WO2010060934A3 WO 2010060934 A3 WO2010060934 A3 WO 2010060934A3 EP 2009065848 W EP2009065848 W EP 2009065848W WO 2010060934 A3 WO2010060934 A3 WO 2010060934A3
Authority
WO
WIPO (PCT)
Prior art keywords
cnnm
proteins
cnnm1
cnnm2
cnnm4
Prior art date
Application number
PCT/EP2009/065848
Other languages
English (en)
Other versions
WO2010060934A2 (fr
Inventor
Daniel François SCHORDERET
Pascal André ESCHER
Bozena Karolina Polok
Original Assignee
Ecole Polytechnique Federale De Lausanne (Epfl)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ecole Polytechnique Federale De Lausanne (Epfl) filed Critical Ecole Polytechnique Federale De Lausanne (Epfl)
Publication of WO2010060934A2 publication Critical patent/WO2010060934A2/fr
Publication of WO2010060934A3 publication Critical patent/WO2010060934A3/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4738Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/16Ophthalmology
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/18Dental and oral disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Microbiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne des protéines du groupe constitué de CNNM1, CNNM2, CNNM3 et CNNM4, des dérivés ou des fragments de celles-ci pour utilisation en tant que médicament, pour des applications de traitement et/ou de diagnostic. L’invention concerne en outre une séquence d’ADN génomique humain, ADNc ou ARNm codant pour une protéine fonctionnelle choisie dans le groupe constitué de CNNM1, CNNM2, CNNM3 et CNNM4 et des dérivés ou fragments fonctionnels de celles-ci.
PCT/EP2009/065848 2008-11-25 2009-11-25 Protéines cnnm et utilisations de celles-ci WO2010060934A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11775008P 2008-11-25 2008-11-25
US61/117,750 2008-11-25

Publications (2)

Publication Number Publication Date
WO2010060934A2 WO2010060934A2 (fr) 2010-06-03
WO2010060934A3 true WO2010060934A3 (fr) 2010-07-29

Family

ID=42123173

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/065848 WO2010060934A2 (fr) 2008-11-25 2009-11-25 Protéines cnnm et utilisations de celles-ci

Country Status (1)

Country Link
WO (1) WO2010060934A2 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003008557A2 (fr) * 2001-07-19 2003-01-30 University Of Florida Activateurs de kinases dependant des cyclines
WO2007130423A2 (fr) * 2006-05-01 2007-11-15 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Marqueurs biologiques de tissu de plaie chronique et méthodes d'utilisation pour des critères de débridement chirurgical

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003008557A2 (fr) * 2001-07-19 2003-01-30 University Of Florida Activateurs de kinases dependant des cyclines
WO2007130423A2 (fr) * 2006-05-01 2007-11-15 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Marqueurs biologiques de tissu de plaie chronique et méthodes d'utilisation pour des critères de débridement chirurgical

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DOWNEY L.M. ET AL.: "Identification of a locus on chromosome 2q11 at which recessive amelogenesis imperfecta and cone-rod dystrophy cosegregate.", EUR. J. HUM. GENET., vol. 10, 2002, pages 865 - 869, XP002581334 *
GOYTAIN ANGELA ET AL: "Functional characterization of ACDP2 (ancient conserved domain protein), a divalent metal transporter", PHYSIOLOGICAL GENOMICS, AMERICAN PHYSIOLOGICAL SOCIETY, US LNKD- DOI:10.1152/PHYSIOLGENOMICS.00058.2005, vol. 22, no. 3, 11 August 2005 (2005-08-11), pages 382 - 389, XP002535555, ISSN: 1094-8341 *
GUO D. ET AL.: "Physical interaction and functional coupling between ACDP4 and te intracellular chaperone COXII, an implication of the role of ACDP4 in essentila metal ion transport and homeostasis.", MOLECULAR PAIN, vol. 1, 15, April 2005 (2005-04-01), XP002581333 *
MICHAELIDES M. ET AL.: "Progressive cone and cone-rod dystrophies : phenotypes and underlying molecular genetic basis.", SURVEY OF OPHTHALMOLOGY, vol. 51, no. 3, 2006, pages 232 - 258, XP002581335 *
WANG C-Y ET AL: "Molecular cloning and characterization of a novel gene family of four ancient conserved domain proteins (ACDP)", GENE, ELSEVIER, AMSTERDAM, NL LNKD- DOI:10.1016/S0378-1119(02)01210-6, vol. 306, 13 March 2003 (2003-03-13), pages 37 - 44, XP004416777, ISSN: 0378-1119 *

Also Published As

Publication number Publication date
WO2010060934A2 (fr) 2010-06-03

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