WO2010055529A3 - Nontoxic, water-soluble and functionalized transition metal ion doped semiconductor nanocrystals and a process for the preparation thereof - Google Patents

Nontoxic, water-soluble and functionalized transition metal ion doped semiconductor nanocrystals and a process for the preparation thereof Download PDF

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Publication number
WO2010055529A3
WO2010055529A3 PCT/IN2009/000613 IN2009000613W WO2010055529A3 WO 2010055529 A3 WO2010055529 A3 WO 2010055529A3 IN 2009000613 W IN2009000613 W IN 2009000613W WO 2010055529 A3 WO2010055529 A3 WO 2010055529A3
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WO
WIPO (PCT)
Prior art keywords
transition metal
metal ion
ion doped
semiconductor nanocrystals
nontoxic
Prior art date
Application number
PCT/IN2009/000613
Other languages
French (fr)
Other versions
WO2010055529A2 (en
Inventor
Nikhil Ranjan Jana
Narayan Pradhan
Sarma Dipankar Das
Original Assignee
Indian Association For The Cultivation Of Science
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indian Association For The Cultivation Of Science filed Critical Indian Association For The Cultivation Of Science
Publication of WO2010055529A2 publication Critical patent/WO2010055529A2/en
Publication of WO2010055529A3 publication Critical patent/WO2010055529A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/588—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with semiconductor nanocrystal label, e.g. quantum dots
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/08—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials
    • C09K11/88—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing selenium, tellurium or unspecified chalcogen elements
    • C09K11/881—Chalcogenides
    • C09K11/883—Chalcogenides with zinc or cadmium

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Materials Engineering (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Luminescent Compositions (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The present invention deals with nontoxic, water soluble and functionalized transition metal ion doped ZnS semiconductor nanocrystals. These nanocrystals are effective in fluorescent biological labeling and can be used as bioconjugates useful for different biomedical applications. The present invention further includes within its scope a process for preparing these functionalized transition metal ion doped semiconductor nanocrystals comprising the steps of polymer coating, polymerization followed by purification and functionalization, providing long shelf life. The present invention also includes a process of fluorescence biological labeling with the nontoxic, water soluble and functionalized transition metal ion doped semiconductor nanocrystals for long term cell imaging applications.
PCT/IN2009/000613 2008-11-14 2009-10-28 Nontoxic, water-soluble and functionalized transition metal ion doped semiconductor nanocrystals and a process for the preparation thereof WO2010055529A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN200/KOL/2008 2008-11-14
IN200KO2008 2008-11-14

Publications (2)

Publication Number Publication Date
WO2010055529A2 WO2010055529A2 (en) 2010-05-20
WO2010055529A3 true WO2010055529A3 (en) 2013-02-28

Family

ID=42170486

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2009/000613 WO2010055529A2 (en) 2008-11-14 2009-10-28 Nontoxic, water-soluble and functionalized transition metal ion doped semiconductor nanocrystals and a process for the preparation thereof

Country Status (1)

Country Link
WO (1) WO2010055529A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005118702A2 (en) * 2004-06-01 2005-12-15 The Penn State Research Foundation Unagglomerated core/shell nanocomposite particles
US20070194279A1 (en) * 2005-04-25 2007-08-23 Board Of Trustees Of The University Of Arkansas Doped semiconductor nanocrystals and methods of making same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005118702A2 (en) * 2004-06-01 2005-12-15 The Penn State Research Foundation Unagglomerated core/shell nanocomposite particles
US20070194279A1 (en) * 2005-04-25 2007-08-23 Board Of Trustees Of The University Of Arkansas Doped semiconductor nanocrystals and methods of making same

Also Published As

Publication number Publication date
WO2010055529A2 (en) 2010-05-20

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