WO2010048264A3 - Procédés et compositions pour le traitement de troubles immuno-inflammatoires - Google Patents

Procédés et compositions pour le traitement de troubles immuno-inflammatoires Download PDF

Info

Publication number
WO2010048264A3
WO2010048264A3 PCT/US2009/061446 US2009061446W WO2010048264A3 WO 2010048264 A3 WO2010048264 A3 WO 2010048264A3 US 2009061446 W US2009061446 W US 2009061446W WO 2010048264 A3 WO2010048264 A3 WO 2010048264A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
treatment
methods
immunoinflammatory disorders
nortriptyline
Prior art date
Application number
PCT/US2009/061446
Other languages
English (en)
Other versions
WO2010048264A2 (fr
Inventor
Mahesh V. Padval
Todd W. Chappell
Original Assignee
Combinatorx, Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Combinatorx, Incorporated filed Critical Combinatorx, Incorporated
Publication of WO2010048264A2 publication Critical patent/WO2010048264A2/fr
Publication of WO2010048264A3 publication Critical patent/WO2010048264A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Abstract

L'invention porte sur un procédé de traitement d'un patient diagnostiqué avec, ou à risque de développer, un trouble immuno-inflammatoire dermique par administration topique au patient de loratadine et de nortriptyline. L'invention porte également sur des formes posologiques topiques contenant de la loratadine et de la nortriptyline.
PCT/US2009/061446 2008-10-23 2009-10-21 Procédés et compositions pour le traitement de troubles immuno-inflammatoires WO2010048264A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10788508P 2008-10-23 2008-10-23
US61/107,885 2008-10-23

Publications (2)

Publication Number Publication Date
WO2010048264A2 WO2010048264A2 (fr) 2010-04-29
WO2010048264A3 true WO2010048264A3 (fr) 2010-08-19

Family

ID=42119950

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/061446 WO2010048264A2 (fr) 2008-10-23 2009-10-21 Procédés et compositions pour le traitement de troubles immuno-inflammatoires

Country Status (1)

Country Link
WO (1) WO2010048264A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2549987C1 (ru) * 2014-06-17 2015-05-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Башкирский государственный медицинский университет" Министерства здравоохранения Российской Федерации Средство для ускорения заживления ран и регенерации тканей
GB2540764A (en) * 2015-07-24 2017-02-01 Fontus Health Ltd Topical composition
DE102017215154A1 (de) * 2017-08-30 2019-02-28 Markus Bläss Zusammensetzung zur topischen Behandlung von nicht-Mikroorganismus-verursachten entzündlichen Haut- und Schleimhauterkrankungen

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003006026A1 (fr) * 2001-07-09 2003-01-23 Combinatorx, Incorporated Combinaisons pour le traitement de troubles inflammatoires
US20050192261A1 (en) * 2003-09-15 2005-09-01 Jost-Price Edward R. Methods and reagents for the treatment of immunoinflammatory disorders
WO2007056457A2 (fr) * 2005-11-09 2007-05-18 Combinatorx, Incorporated Procedes, compositions et kits pour le traitement de pathologies

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003006026A1 (fr) * 2001-07-09 2003-01-23 Combinatorx, Incorporated Combinaisons pour le traitement de troubles inflammatoires
US20050192261A1 (en) * 2003-09-15 2005-09-01 Jost-Price Edward R. Methods and reagents for the treatment of immunoinflammatory disorders
WO2007056457A2 (fr) * 2005-11-09 2007-05-18 Combinatorx, Incorporated Procedes, compositions et kits pour le traitement de pathologies

Also Published As

Publication number Publication date
WO2010048264A2 (fr) 2010-04-29

Similar Documents

Publication Publication Date Title
WO2012062925A3 (fr) Composés et procédés de traitement de la douleur
EA201590655A8 (ru) Комбинация лахинимода и придопидина для лечения нейродегенеративных нарушений
WO2007103373A3 (fr) Compositions et procédés pour le traitement de troubles immunoinflammatoires
WO2011008931A3 (fr) Composés arylpyrimidines et thérapie de combinaison comprenant ceux-ci pour traiter une mucoviscidose et des troubles apparentés
WO2011014255A8 (fr) Traitement de la maladie de crohn au moyen de laquinimod
WO2013061161A3 (fr) Nouvelles polythérapies destinées au traitement de troubles neurologiques
EA201001771A1 (ru) Лечение релаксином одышки, ассоциированной с острой сердечной недостаточностью
WO2007085019A3 (fr) Procédés pour traiter ou prévenir la sinusite au moyen d'une solution aqueuse à potentiel d'oxydo-réduction
EA201290041A1 (ru) Лечение расстройств, связанных с макрофагами
EP2581092A4 (fr) Agent améliorant le métabolisme des lipides
MX2010006823A (es) Metodos para el tratamiento de la gota.
WO2012050831A3 (fr) Traitement combiné d'affections dermatologiques
MY153062A (en) Methods of treating gastrointestinal disorders independent of the intake of food
WO2012015758A3 (fr) Méthodes de traitement de la douleur
WO2008095086A3 (fr) Topiramate plus naltrexone pour le traitement de troubles addictifs
EA201590654A1 (ru) Комбинация разагилина и придопидина для лечения нейродегенеративных нарушений, в частности болезни хантингтона
WO2009140657A3 (fr) Méthode de traitement de l'insuffisance cardiaque chronique
WO2011090270A3 (fr) Composition contenant de l'osmotine pour prévenir et traiter des troubles neurologiques
WO2011112867A8 (fr) Utilisation du fénotérol et de ses analogues dans le traitement de glioblastomes et d'astrocytomes
WO2012170918A3 (fr) Procédés de traitement pour des maladies rétiniennes
WO2008097924A3 (fr) Compositions pharmaceutiques comprenant des analogues du dextrométhorphane pour le traitement de troubles neurologiques
WO2012142300A3 (fr) Procédé de détermination d'un protocole de traitement et/ou d'un pronostic de rétablissement d'un patient à la suite d'un traumatisme cérébral provenant d'un événement hypoxique
WO2006138372A3 (fr) Procedes et reactifs pour le traitement de troubles inflammatoires
WO2007087457A3 (fr) Polytherapie destinee au traitement de troubles neovasculaires
WO2011019963A3 (fr) Traitement de prg4 pour cystite interstitielle

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09822610

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 09822610

Country of ref document: EP

Kind code of ref document: A2