WO2010046592A3 - Use of isolated polypeptides having antigenic properties against mycoplasma pneumoniae, and of corresponding polynucleotides and antibodies - Google Patents

Use of isolated polypeptides having antigenic properties against mycoplasma pneumoniae, and of corresponding polynucleotides and antibodies Download PDF

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Publication number
WO2010046592A3
WO2010046592A3 PCT/FR2009/052000 FR2009052000W WO2010046592A3 WO 2010046592 A3 WO2010046592 A3 WO 2010046592A3 FR 2009052000 W FR2009052000 W FR 2009052000W WO 2010046592 A3 WO2010046592 A3 WO 2010046592A3
Authority
WO
WIPO (PCT)
Prior art keywords
antibodies
mycoplasma pneumoniae
isolated polypeptides
properties against
antigenic properties
Prior art date
Application number
PCT/FR2009/052000
Other languages
French (fr)
Other versions
WO2010046592A2 (en
Inventor
Camille Cyncynatus
Hélène NUYTTENS
Julie Roge
Damien Thomas
Original Assignee
Ingen Biosciences
Universite Victor Segalen Bordeaux 2
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ingen Biosciences, Universite Victor Segalen Bordeaux 2 filed Critical Ingen Biosciences
Priority to EP09760179A priority Critical patent/EP2353009A2/en
Publication of WO2010046592A2 publication Critical patent/WO2010046592A2/en
Publication of WO2010046592A3 publication Critical patent/WO2010046592A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56933—Mycoplasma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0241—Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/30—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycoplasmatales, e.g. Pleuropneumonia-like organisms [PPLO]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1253—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Mycoplasmatales, e.g. Pleuropneumonia-like organisms [PPLO]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/30—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycoplasmatales, e.g. Pleuropneumonia-like organisms [PPLO]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms

Abstract

The present invention relates to the use of an isolated polypeptide of the amino acid sequence SEQ ID NO: 2, 4, 6, 8, 10, 12, 14, 16, or 18 for detecting, in vitro and in biological samples, the presence of antibodies generated after a Mycoplasma pneumoniae infection.
PCT/FR2009/052000 2008-10-23 2009-10-20 Use of isolated polypeptides having antigenic properties against mycoplasma pneumoniae, and of corresponding polynucleotides and antibodies WO2010046592A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP09760179A EP2353009A2 (en) 2008-10-23 2009-10-20 Use of isolated polypeptides having antigenic properties against mycoplasma pneumoniae, and of corresponding polynucleotides and antibodies

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0805874 2008-10-23
FR0805874A FR2937738B1 (en) 2008-10-23 2008-10-23 USE OF ISOLATED POLYPEPTIDES HAVING ANTIGENIC PROPERTIES TO MYCOPLASMA PNEUMONIAE, AND CORRESPONDING POLYNUCLEOTIDES AND ANTIBODIES

Publications (2)

Publication Number Publication Date
WO2010046592A2 WO2010046592A2 (en) 2010-04-29
WO2010046592A3 true WO2010046592A3 (en) 2010-06-24

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2009/052000 WO2010046592A2 (en) 2008-10-23 2009-10-20 Use of isolated polypeptides having antigenic properties against mycoplasma pneumoniae, and of corresponding polynucleotides and antibodies

Country Status (3)

Country Link
EP (1) EP2353009A2 (en)
FR (1) FR2937738B1 (en)
WO (1) WO2010046592A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9593150B2 (en) * 2012-07-16 2017-03-14 The Scripps Research Institute Immunoglobulin-binding human mycoplasma antigens and methods of use thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0254384A2 (en) * 1986-03-27 1988-01-27 Cetus Corporation Direct and simultaneous assays for antigens in clinical specimens by monoclonal antibody immunoblot, antibodies for use therein and corresponding hybridomas
US6171589B1 (en) * 1995-12-13 2001-01-09 The University Of Melbourne Mycoplasma recombinant polypeptides and vaccines
US20030170663A1 (en) * 1995-06-07 2003-09-11 Johns Hopkins University Nucleotide sequence of the Mycoplasma genitalium genome, fragments thereof, and uses thereof
US20070212378A1 (en) * 2003-10-03 2007-09-13 Baseman Joel B Methods And Compositions For Mycoplasma Pneumoniae Exotoxins

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0254384A2 (en) * 1986-03-27 1988-01-27 Cetus Corporation Direct and simultaneous assays for antigens in clinical specimens by monoclonal antibody immunoblot, antibodies for use therein and corresponding hybridomas
US20030170663A1 (en) * 1995-06-07 2003-09-11 Johns Hopkins University Nucleotide sequence of the Mycoplasma genitalium genome, fragments thereof, and uses thereof
US6171589B1 (en) * 1995-12-13 2001-01-09 The University Of Melbourne Mycoplasma recombinant polypeptides and vaccines
US20070212378A1 (en) * 2003-10-03 2007-09-13 Baseman Joel B Methods And Compositions For Mycoplasma Pneumoniae Exotoxins

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DANDEKAR T. ET AL.: "Re-annotating the Mycoplasma pneumoniae genome sequence: adding value, function and reading frames", NUCLEIC ACIDS RES., vol. 28, no. 17, 2000, pages 3278 - 3288, XP003008959 *
HIMMELREICH R. ET AL.: "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae", NUCLEIC ACIDS RES., vol. 24, no. 22, 1996, pages 4420 - 4449, XP002172064 *

Also Published As

Publication number Publication date
EP2353009A2 (en) 2011-08-10
WO2010046592A2 (en) 2010-04-29
FR2937738A1 (en) 2010-04-30
FR2937738B1 (en) 2013-02-15

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