WO2010038936A1 - Unité de rétroéclairage avec fonction de soins de santé - Google Patents

Unité de rétroéclairage avec fonction de soins de santé Download PDF

Info

Publication number
WO2010038936A1
WO2010038936A1 PCT/KR2009/003775 KR2009003775W WO2010038936A1 WO 2010038936 A1 WO2010038936 A1 WO 2010038936A1 KR 2009003775 W KR2009003775 W KR 2009003775W WO 2010038936 A1 WO2010038936 A1 WO 2010038936A1
Authority
WO
WIPO (PCT)
Prior art keywords
light
backlight unit
leds
health
lighting
Prior art date
Application number
PCT/KR2009/003775
Other languages
English (en)
Inventor
Tae-Young Kwon
Original Assignee
Qray Inc.
Lim, Jeong-Hoon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020080096877A external-priority patent/KR100900248B1/ko
Application filed by Qray Inc., Lim, Jeong-Hoon filed Critical Qray Inc.
Publication of WO2010038936A1 publication Critical patent/WO2010038936A1/fr

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0642—Irradiating part of the body at a certain distance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/065—Light sources therefor
    • A61N2005/0651—Diodes
    • A61N2005/0652—Arrays of diodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662—Visible light

Definitions

  • the following description relates to a backlight unit, and more particularly, to a light source of a backlight unit.
  • a TFT-LCD can include three units: a panel in which liquid crystal is injected between two substrates; a printed circuit board (PCB) on which a driver LSI (large-scale integration) for driving the panel and various circuit devices are mounted; and a chassis structure including a backlight for providing a light source.
  • the backlight is essential because the TFT-LCD itself cannot radiate light.
  • the light source used in the backlight may be a fluorescent lamp, LED lamp, etc.
  • a Cold Cathode Fluorescent Lamp (CCFL) has commonly been used as a light source for a backlight, but the introduction of LCDs onto the market is revealing many problems in price competitiveness, process improvement, etc. Accordingly, LEDs, which have advantages of good color reproduction, high luminous efficiency, low power consumption, light weight, thinness, etc., are being adopted as a light source for a backlight.
  • Immune function can be classified into two types: one is humoral immunity which antibodies such as immunoglobulin mediate, and the other is cell-mediated immunity managed by T lymphocytes.
  • Visible light can influence both types of immunity. Irradiation by ultraviolet light usually only effects the skin, because short-wavelength ultraviolet light cannot pass through the dermis. Thus, it mainly acts to control cell-mediated immunity in the skin. Since visible light having the wavelength range of 380-780 nm penetrates the outer and inner layers of the skin and reaches superficial blood vessels, visible light can influence the blood as well as the skin.
  • T lymphocytes which manage a central function of cell-mediated immunity, play a central role in acceleration of wound healing using visible light.
  • the following description relates to a backlight unit for improving the immunity of the human body.
  • a backlight unit with a health-care function including: a light source including a plurality of light-emitting diodes (LEDs), at least some of the plurality of LEDs radiating light having a wavelength beneficial to the human body; and an optical output unit outputting the light radiated from the light source to a liquid crystal panel.
  • a light source including a plurality of light-emitting diodes (LEDs), at least some of the plurality of LEDs radiating light having a wavelength beneficial to the human body
  • an optical output unit outputting the light radiated from the light source to a liquid crystal panel.
  • the at least some of the LEDs radiates light having an incoherent wavelength of 610 ⁇ 20 nm or 710 ⁇ 30 nm.
  • a display such as a monitor or an LCD for a cellular phone, in which the backlight unit is adopted can improve the immunity of the human body. Particularly, when a user who has to work on a computer for many hours uses a monitor with the backlight unit, he or she may gain the benefit of naturally improved immunity only by spending time in front of the monitor.
  • FIG. 1 is a block diagram of a backlight unit according to an embodiment of the present invention
  • FIG. 2 shows an example of a plurality of light sources having the structure shown in FIG. 1 arranged on a substrate;
  • FIG. 3 shows an example of two light-emitting diodes (LEDs) connected in parallel
  • FIG. 4 shows an example of a lighting package
  • FIG. 5 is a cross-sectional view showing a light guide panel and a lighting package that is to be inserted into the light guide panel;
  • FIG. 6 is a cross-sectional view showing a light guide panel and a lighting package inserted into the light guide panel
  • FIG. 7 is a diagram showing results obtained by measuring CD4+ and CD8+ T-cell population of experimental groups using a flow cytometer before the experimental groups are irradiated by LED light;
  • FIG. 8 is a diagram showing results obtained by measuring CD4+ and CD8+ T-cell population of experimental groups using a flow cytometer after the experimental groups are irradiated by LED light for 28 days;
  • FIG. 9 is a flow cytometry data diagram showing the distributions of CD4+ and CD8+ T-cell population of experimental groups after the experimental groups are irradiated by 610 nm and 710 nm LED light for 4 weeks;
  • FIG. 10 is a diagram showing results obtained by measuring CD4+ and CD8+ T-cell population of experimental groups using a flow cytometer after irradiation of the experimental groups by LED light is stopped for 5 weeks;
  • FIG. 11 is a photograph of Interleukin 1 (IL-1 ⁇ ) Polymerase Chain Reaction (PCR) products
  • FIG. 12 is a photograph of IL-4 PCR products
  • FIG. 13 is a photograph of IL-6 PCR products.
  • FIG. 14 is a photograph of IFN ⁇ PCR products.
  • the present invention is different from other conventional techniques in terms of wavelength band and optical interference. Particularly, while conventional low-density phototherapy using short-wavelength narrowband light affects localized parts of a human body, the present invention uses visible light of a specific wavelength band capable of improving cell-mediated immunity of the entire human body.
  • FIG. 1 is a block diagram of a backlight unit according to an embodiment of the present invention.
  • the backlight unit includes a light source 100 and an optical output unit 200.
  • the light source 100 includes a plurality of light-emitting diodes (LEDs). At least some of the LEDs have a specific visible light wavelength which is beneficial to the human body. According to an aspect of the present invention, some of the LEDs radiate light of a specific incoherent wavelength in the range of 610 ⁇ 20 nm or 710 ⁇ 30 nm, or more restrictively, 610 ⁇ 5 nm or 710 ⁇ 5 nm.
  • the optical output unit 200 is used to output light radiated from the light source 100 to a display panel which cannot emit light by itself.
  • the optical output unit 200 includes a light guide panel, a diffusion sheet, a prism sheet, etc.
  • the light guide panel may or may not be included in the backlight unit depending on the type of the backlight unit.
  • the backlight unit can be classified as a light guide panel type or a direct type according to the position of a light source.
  • a light source is disposed at a side of a light guide panel (LGP), a light beam from the light source is converted into a surface light source when passing through the light guide panel, and the surface light source illuminates a display panel.
  • LGP light guide panel
  • a light source radiates light from the rear side of a display panel toward the front side.
  • the direct type backlight requires no light guide panel since it radiates light from the rear side of a display panel toward the front side.
  • a light guide type backlight can be classified as a wedge type LGP in which a light source is disposed at a side of a slanting light guide panel, or a flat type LGP in which light sources are disposed at both sides of a light guide panel. Since the wedge type LGP uses a linear light source in which LEDs are connected in a line and accordingly a small number of LEDs is used, the wedge type LGP is mainly used in an LCD for a notebook computer requiring low power consumption.
  • the flat type LGP which is aimed at high brightness, since light sources are disposed at both sides of a light guide panel and accordingly the flat type LGP is thick, the flat type LGP is mainly used in a monitor. Also, the direct type is mainly used in applications such as LCD TVs requiring a large size and high brightness.
  • the backlight unit can further include a filter, which is not shown in the drawings.
  • the filter is used to sharply limit the wavelength band characteristics of visible light radiated from LEDs. By sharply limiting the wavelength band of light emitted from LEDs using the filter, the effects of 610 or 710 nm light on immunity can be maximized.
  • a plurality of LEDs are constructed as a plurality of lighting packages which appear like a single lighting.
  • the lighting packages may be general lighting packages functioning as backlights in the backlight unit, or health-care lighting packages.
  • LEDs included in the health-care lighting packages radiate visible light of a specific incoherent wavelength in the wavelength range of 610 ⁇ 20 nm (610 ⁇ 5 nm) or 710 ⁇ 30 nm (710 ⁇ 5 nm).
  • the general lighting packages are RGB LEDs radiating light with red (R), green (G) and blue (B) colors.
  • FIG. 2 shows an example of the lighting packages of the backlight unit arranged on a substrate 300.
  • general lighting packages 110 functioning as backlights are represented by white and health-care lighting packages 120 are represented by black.
  • the general lighting packages 110 and the health-care lighting packages 120 are arranged in alternating fashion. This arrangement is aimed to uniformly radiate light having a wavelength beneficial to the human body throughout the entire display panel.
  • LEDs 121 and 123 constructing each health-care lighting package 120 are connected to each other in parallel, as illustrated in FIG. 3. Accordingly, only two electrodes 125 (see FIG. 4) of each health-care lighting package 120 are exposed to the outside. By electrically connecting only two electrodes of each lighting package 120 to neighboring LEDs, a process of configuring electrodes can be simplified compared to a serial connection method.
  • the general lighting packages can further include one or more LEDs for radiating visible light of a specific incoherent wavelength in the wavelength range of 610 ⁇ 20 nm (610 ⁇ 5 nm) or 710 ⁇ 30 nm (710 ⁇ 5 nm).
  • the backlight unit according to the present invention can be implemented by installing one or more LEDs for radiating visible light of a specific incoherent wavelength in the wavelength range of 610 ⁇ 20 nm (610 ⁇ 5 nm) or 710 ⁇ 30 nm (710 ⁇ 5 nm) in general lighting packages which are RGB LEDs, without installing separate health-care lighting packages. That is, it is possible to install one or more LEDs for radiating light having a wavelength which is beneficial to the human body in general lighting packages which have been conventionally used in a backlight, without having to install separate health-care lighting packages.
  • the lighting packages are inserted respectively into holes formed in a light guide panel.
  • a health-care lighting package 120 (or a general lighting package) is inserted into a hole 213 formed in a light guide panel 210.
  • This structure is suitable for a mobile communication terminal such as a mobile phone requiring a small size.
  • the present applicant adopted, as a light source for a backlight unit, LEDs for radiating light in wavelength bands centered on 610 nm and 710 nm in the visible light region to effectively interact with T lymphocytes. Then, the present applicant performed a test of applying LED light to the in vivo rat model. The aim of the test was to investigate the effects of LED irradiation at 610 nm and 710 nm on T lymphocyte subset population using Flow cytometric assay and reverse transcriptase-polymerase chain reaction (RT-PCR) when the LED light is applied to the in vivo rat model. The test was performed as follows.
  • the devices were equipped with filters to block unneeded light beyond the target wavelength range and were pointed towards the animals in direct contact with the outer surface of the cage.
  • Each subject in the experimental group of 610nm or 710nm was irradiated by an LED device for 12 hours per day in accordance with the light cycle, while the control subjects were not exposed to LED light at all.
  • the LED devices were provided by Qray Corporation (Seongnam, Korea) and the photometric features were measured by spectrometric instruments (CAS 140CT, Instrument systems GmbH, Kunststoff, Germany). The treatment was continued for 28 consecutive days.
  • PBMC Peripheral blood mononuclear cells
  • QiaAmp RNA blood mini Qiagen, Hilden, Germany
  • PCR polymerase chain reaction
  • the sequence of PCR primers for IL-1 ⁇ IL-4, IL-6, and IFN ⁇ were listed in Table 1. After samples had been denatured at 94°C for 2 minutes, the PCR amplification was performed for 30 cycles. Each PCR cycle consisted of a melting at 94°C for 20 seconds, an annealing at 58°C for 40 seconds, and an elongation at 72°C for 1 minute. The PCR products were visualized on 1% agarose gel.
  • IL-1 Sense 5'-CTGTCCTGATGAGAGCATCC-3' 330 Reverse 5'-TGTCCATTGAGGTGGAGAGC-3' IFN ⁇ Sense 5'-GCTGTTACTGCCAAGGCACA-3' 400 Reverse 5'-CGACTCCTTTTCCGCTTCCT-3' IL-4 Sense 5'-GAGCTATTGATGGGTCTCAGC-3' 400 Reverse 5'-GGCTTTCCAGGAAGTCTTTCA-3' IL-6 Sense 5'-ACAAGTCCGGAGAGGAGACT-3' 490 Reverse 5'-GGATGGTCTTGGTCCTTAGC-3'
  • FIG. 7 is a diagram showing results obtained by measuring CD4+ and CD8+ T-cell population using a flow cytometer before LED light irradiation
  • FIG. 8 is a diagram showing results obtained by measuring CD4+ and CD8+ T-cell population using a flow cytometer after LED light irradiation for 28 days.
  • CD4+ T-cell subset population of 710nm LED-irradiated rats increased significantly (p ⁇ 0.05), but the same result was not found in the 610nm group and control group.
  • the percentile population of CD8+ T-cells decreased apparently in LED-irradiated groups, but the decrease was statistically insignificant.
  • FIG. 9 is a flow cytometry data diagram showing the distributions of CD4+ and CD8+ T-cell subset population of experimental groups after LED irradiation of the experimental groups for 4 weeks.
  • PBMC peripheral blood sample
  • the PBMC was stained by PE-conjugated anti-rat-CD4 antibody or by PE-conjugated anti-rat-CD8a antibody, and then flow cytometry was applied to the control rat group (A), the 610 nm LED-irradiated rat group (B), and the 710 nm LED-irradiated rat group (C).
  • FIG. 10 is a diagram showing results obtained by measuring CD4+ and CD8+ T-cell population of experimental groups using a flow cytometer after the experimental groups were deprived of LED light for 5 weeks. After 4 weeks of LED phototherapy, the rats in the 710 nm group were deprived of LED light for 5 weeks in order to check if the increased CD4+ T-cell subset population could be reversed. Without the 710 nm LED irradiation, the CD4+ T-cell subset population returned to the control level.
  • the transcript level of IL-1 slightly increased in the 710nm group (FIG. 11) and the transcript level of IL-6 increased weakly in both the 610nm and 710nm LED groups compared to the control group (FIG. 13). IFN ⁇ transcripts were not detected in any group (FIG. 14).
  • LED visible light having a 710nm or 610 nm wavelength on the proliferation and activation of CD4+ T lymphocytes which play a central role in cell-mediated immunity indicate that 710 nm and 610 nm visible light can be useful tools in immunotherapy.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

L'invention porte sur une unité de rétroéclairage qui présente une fonction de soins de santé. L'unité de rétroéclairage comprend : une source de lumière qui comprend une pluralité de diodes électroluminescentes (DEL), dont au moins certaines de la pluralité de DEL irradient de la lumière ayant une longueur d'onde favorable au corps humain, et une unité de sortie optique émettant la lumière irradiée à partir de la source de lumière vers un panneau à cristaux liquides. A l'aide d'un moniteur ou d'un téléphone mobile adoptant l'unité de rétroéclairage, l'immunité est améliorée.
PCT/KR2009/003775 2008-10-02 2009-07-09 Unité de rétroéclairage avec fonction de soins de santé WO2010038936A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2008-0096877 2008-10-02
KR1020080096877A KR100900248B1 (ko) 2008-03-17 2008-10-02 헬스 케어 역할을 갖는 백라이트 유닛

Publications (1)

Publication Number Publication Date
WO2010038936A1 true WO2010038936A1 (fr) 2010-04-08

Family

ID=42074443

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/003775 WO2010038936A1 (fr) 2008-10-02 2009-07-09 Unité de rétroéclairage avec fonction de soins de santé

Country Status (1)

Country Link
WO (1) WO2010038936A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1619648A1 (fr) * 2003-03-28 2006-01-25 Sharp Kabushiki Kaisha Dispositif d'affichage
US20060217787A1 (en) * 2005-03-23 2006-09-28 Eastman Kodak Company Light therapy device
US20070208395A1 (en) * 2005-10-05 2007-09-06 Leclerc Norbert H Phototherapy Device and Method of Providing Phototherapy to a Body Surface
WO2008017975A1 (fr) * 2006-08-07 2008-02-14 Koninklijke Philips Electronics N.V. Système de plâtre et dispositif de rayonnement
WO2008146220A2 (fr) * 2007-05-25 2008-12-04 Koninklijke Philips Electronics N.V. Système d'éclairage
WO2008152558A1 (fr) * 2007-06-15 2008-12-18 Koninklijke Philips Electronics N.V. Dispositif d'éclairage amélioré

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1619648A1 (fr) * 2003-03-28 2006-01-25 Sharp Kabushiki Kaisha Dispositif d'affichage
US20060217787A1 (en) * 2005-03-23 2006-09-28 Eastman Kodak Company Light therapy device
US20070208395A1 (en) * 2005-10-05 2007-09-06 Leclerc Norbert H Phototherapy Device and Method of Providing Phototherapy to a Body Surface
WO2008017975A1 (fr) * 2006-08-07 2008-02-14 Koninklijke Philips Electronics N.V. Système de plâtre et dispositif de rayonnement
WO2008146220A2 (fr) * 2007-05-25 2008-12-04 Koninklijke Philips Electronics N.V. Système d'éclairage
WO2008152558A1 (fr) * 2007-06-15 2008-12-18 Koninklijke Philips Electronics N.V. Dispositif d'éclairage amélioré

Similar Documents

Publication Publication Date Title
Bacellar et al. Up-regulation of Th1-type responses in mucosal leishmaniasis patients
Shin et al. Human periodontal ligament stem cells suppress T‐cell proliferation via down‐regulation of non‐classical major histocompatibility complex‐like glycoprotein CD 1b on dendritic cells
WO2013185368A1 (fr) Module de rétroéclairage et écran à cristaux liquides
EP1503139A3 (fr) Dispositif d'éclairage à DEL
EP1918770A3 (fr) Rétro-éclairage à LED avec une diode électroluminescente sur puce nue
IL165350A0 (en) Light emitting microorganisms and cells for diagnosis and therapy of diseases associated with wounded or inflamed tissue
WO2020067742A1 (fr) Dispositif de détection de fluorescence d'amplification en chaîne par polymérase, en temps réel
CN101015724A (zh) 用于产生光电子的促进细胞活性的方法
Díaz-Zúñiga et al. Differential human Th22-lymphocyte response triggered by Aggregatibacter actinomycetemcomitans serotypes
WO2010038936A1 (fr) Unité de rétroéclairage avec fonction de soins de santé
Karadag et al. A chromosomal-effect study of intensive phototherapy versus conventional phototherapy in newborns with jaundice
US20090231880A1 (en) Backlight unit with health-care function
TW201122662A (en) A backlight module with localized light source control
US20030071934A1 (en) Liquid crystal backlight utilizing side emitting
WO2020105998A1 (fr) Dispositif d'éclairage à del ayant une fonction de stérilisation
CN101449390A (zh) 发光装置、包括该发光装置的照明装置和液晶显示装置
Jittimanee et al. Opisthorchis viverrini antigens up-regulates the expression of CD80 and MHC class II in JAWSII mouse dendritic cells and promotes IL-10 and TGF-β secretions
CN216984856U (zh) 一种改进的荧光内窥镜冷光源装置
CN113594145B (zh) 一种光源的制备方法
CN102329871B (zh) 低甲基化基因prdm16的应用方法
García-Arévalo et al. Modulation of myeloid-derived suppressor cell functions by oral inflammatory diseases and important oral pathogens
TW201200859A (en) Fluoroscopy light source device
Krutmann et al. UVB radiation and human monocyte accessory function: differential effects on pre-mitotic events in T-cell activation
Chakraborty et al. Dysregulated CC receptor/ligand in monocytes/macrophages from tongue squamous cell carcinoma patients is partially rectified by interferon α-2b
US20240017086A1 (en) Illumination devices, systems and methods

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09817946

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 09817946

Country of ref document: EP

Kind code of ref document: A1