WO2010038182A2 - Drug delivery system - Google Patents

Drug delivery system Download PDF

Info

Publication number
WO2010038182A2
WO2010038182A2 PCT/IB2009/054213 IB2009054213W WO2010038182A2 WO 2010038182 A2 WO2010038182 A2 WO 2010038182A2 IB 2009054213 W IB2009054213 W IB 2009054213W WO 2010038182 A2 WO2010038182 A2 WO 2010038182A2
Authority
WO
WIPO (PCT)
Prior art keywords
drug
drug delivery
delivery device
drug cartridge
unit
Prior art date
Application number
PCT/IB2009/054213
Other languages
French (fr)
Other versions
WO2010038182A3 (en
Inventor
Roelf Kassies
Giovanni Nisato
Wilhelmus H. N. M. Van Mensvoort
Erik A. Pastink
Original Assignee
Koninklijke Philips Electronics N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips Electronics N.V. filed Critical Koninklijke Philips Electronics N.V.
Publication of WO2010038182A2 publication Critical patent/WO2010038182A2/en
Publication of WO2010038182A3 publication Critical patent/WO2010038182A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/002Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M2005/14268Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body with a reusable and a disposable component
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3125Details specific display means, e.g. to indicate dose setting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/12General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/60General characteristics of the apparatus with identification means
    • A61M2205/6045General characteristics of the apparatus with identification means having complementary physical shapes for indexing or registration purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/60General characteristics of the apparatus with identification means
    • A61M2205/6054Magnetic identification systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/82Internal energy supply devices
    • A61M2205/8237Charging means
    • A61M2205/8243Charging means by induction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00Ancillary equipment
    • A61M2209/04Tools for specific apparatus
    • A61M2209/045Tools for specific apparatus for filling, e.g. for filling reservoirs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00Ancillary equipment
    • A61M2209/08Supports for equipment
    • A61M2209/084Supporting bases, stands for equipment
    • A61M2209/086Docking stations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1413Modular systems comprising interconnecting elements

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Warehouses Or Storage Devices (AREA)

Abstract

A drug delivery system (102) comprising a drug delivery device (108) arranged for accommodating a drug cartridge (106) and a drug cartridge loading device (104) for loading the drug cartridge to the drug delivery device. The drug cartridge loading device is provided with a storing unit (110) for storing a drug cartridge, a receiving unit (112) for receiving the drug delivery device, and a transferring unit (114) for transferring the drug cartridge to the drug delivery device during or after receiving the drug delivery device. The drug delivery system reduces the difficulties associated with the handling of relatively small drug cartridges through providing a drug cartridge loading device.

Description

Drug delivery system
FIELD OF THE INVENTION
The invention relates to a drug cartridge loading device for loading a drug cartridge to a drug delivery device, a drug delivery device, a drug cartridge, a drug delivery system and a method for installing a drug cartridge into a drug delivery device.
BACKGROUND OF THE INVENTION
In International Patent Application published under WO 2007/143323 Al, a medication module for an injection device is disclosed. The medication module comprises a supply portion and a loadable portion, which portions are detachably connected together. Once the loadable portion is filled with medication, the supply portion may be moved away from the loadable portion and be disposed of. The loadable portion can then be inserted into the injection device. The loadable portion has a periphery complementarily shaped with a cavity in the injection device to be loadable therein. The loadable portion is enclosed in such a way that it is not moveable except for movement associated with tolerances. The loading of said loadable portion into the medication module disclosed in
WO 2007/143323 Al is difficult, particularly for patients having impaired motor function. In particular, the loading of the loadable portion into the close-fitting cavity of the injection device is cumbersome.
SUMMARY OF THE INVENTION
It is an object of the invention to mitigate the difficulties associated with the handling of drug cartridges, particularly relatively small drug cartridges, for use in transdermal drug delivery devices, both by patients, particularly patients having a motor disfunction, and medical professionals. This object is achieved by the drug cartridge loading device according to the invention, which drug cartridge loading device is arranged for loading a drug cartridge to a drug delivery device arranged for accommodating a drug cartridge, and which cartridge loading device comprises a storing unit for storing a drug cartridge, a receiving unit for receiving the drug delivery device and a transferring unit for transferring the drug cartridge to the drug delivery device during or after receiving the drug delivery device.
The drug cartridge loading device according to the invention reduces the difficulties associated with the handling of relatively small drug cartridges. That is, rather than handling the relatively small drug cartridge, the drug cartridge loading device itself is to be handled. The drug cartridge loading device comprises a receiving unit for receiving the drug delivery unit. That is, the receiving unit is arranged for at least temporarily receiving the drug delivery device in such a way that the transferring unit comprised in the drug cartridge loading device, is enabled to transfer the drug cartridge from the drug loading device to the drug delivery device. As a result, the handling of the drug cartridge itself is effectively circumvented. That is, the difficult handling of the relatively small drug cartridge is replaced by the easy and convenient handling of the relatively large drug cartridge loading device and the relatively large drug delivery device. The latter is especially beneficial for patients having impaired motor function, e.g. patients suffering from Parkinson's disease. Hence, the drug cartridge loading device according to the invention enables patients, particularly patients having impaired motor function, to autonomously medicate their diseases
In a preferred embodiment of the drug cartridge loading device according to the invention, the drug cartridge loading device comprises a display for providing information, for instance information regarding the number of cartridges left in the storage or information giving an overview of drug delivery data. This feature assists the patient in employing the drug delivery system independent from a medical professional.
In a practical embodiment of the drug cartridge loading device according to the invention, the drug cartridge loading device comprises a displacing unit for displacing the at least one drug cartridge from the storing unit to the receiving unit. In a further practical embodiment of the drug cartridge loading device according to the invention, the drug cartridge loading device comprises a battery charger for charging a rechargeable battery of the drug delivery device. As a result, in case the drug delivery device comprises a rechargeable battery, the loading of a drug cartridge in the drug delivery device may be efficiently combined with charging the rechargeable battery. In a preferred embodiment of the drug cartridge loading device according to the invention, the transferring unit comprises an electromagnet for cooperation with a first permanent magnet provided in the drug cartridge. Hence, the drug cartridge and the drug cartridge loading device are attachable to one another via an electromagnetic coupling. An electromagnetic coupling is reliable, that is it contains no moving parts which may be subject to wear and tear.
It is a further object of the invention to provide a drug delivery device arranged for cooperation with the drug cartridge loading device. This object is achieved by the drug delivery device according to the invention, which is characterized by a locking mechanism configured for locking the drug cartridge.
In an embodiment of the drug delivery device according to the invention, the locking mechanism comprised in the drug delivery device is also configured for unlocking the drug cartridge. Hence, the patient is not only assisted in loading the drug cartridge into the drug delivery device; the removal of a drug cartridge from the delivery device is facilitated as well.
In a preferred embodiment of the drug delivery device according to the invention, the locking mechanism comprises a further permanent magnet for cooperation with a second permanent magnet provided in the drug cartridge. Hence, the drug cartridge and the drug delivery device are connectable to one another via electromagnetic coupling. Said electromagnetic coupling enables a quick and easy transfer for the drug cartridge from the drug cartridge loading unit to the drug delivery device. Namely, upon receiving the drug delivery device by the receiving unit, the current supplied to the electromagnet comprised in the drug cartridge loading unit is switched off as to nullify the electromagnetic field imposed by the electromagnet. Subsequently, the further permanent magnet will cause the drug cartridge to displace from the drug cartridge loading unit to the drug delivery device.
In a further preferred embodiment of the drug delivery device according to the invention, the locking device comprises a further electromagnet for cooperation with the second permanent magnet provided in the drug cartridge. For the purpose of unlocking the drug cartridge from the drug delivery device, the further electromagnet is actuated momentary in such a way that its magnetic field cancels the magnetic field imposed by the further permanent magnet. It is noted that the further permanent magnet and the further electromagnet may be constituted by one and the same unit.
In a further embodiment of the drug delivery according to the invention, an informed consent mechanism is comprised in the drug delivery device. The informed consent mechanism may be embodied by a consent display and a consent button. The consent display notifies the patient that therapy related data, such as the usage of drugs and the utilization of the drug delivery device, is transferred to e.g. a medical professional once the drug delivery device is received by the receiving unit and the patient activates the consent button. The drug delivery device according to the invention may be a transdermal drug delivery device. Said transdermal drug delivery device may introduce a medication passively through the skin, e.g. through diffusion. Alternatively, said transdermal drug delivery device forcibly introduces the medication through the skin. For this purpose, the transdermal drug delivery device may employ micro jetting by way of a piezo-electric actuator.
It is a further object of the invention to provide a drug cartridge for cooperation with the drug cartridge loading unit and the drug delivery unit. This object is achieved by the drug cartridge according to the invention, which is characterized by comprising a permanent magnet configured for cooperation with the electromagnet provided in the drug cartridge loading unit and, a further permanent magnet configured for cooperation with the further electromagnet provided in the drug delivery unit.
It is a further object of the invention to provide a way of working circumventing the problems associated with the handling of drug cartridges for use in transdermal drug delivery devices, particularly in case of relatively small drug cartridges, both by patients, particularly patients having impaired motor function, and medical professionals.
This object is achieved by the method according to the invention, which is characterized by the steps of storing a drug cartridge in the storing unit comprised in the drug cartridge loading unit, receiving the drug delivery unit by the receiving unit comprised in the drug cartridge loading unit and transferring the drug cartridge from the drug cartridge loading unit to the drug delivery device by the transferring unit.
Application of the invention is in drug delivery, particularly transdermal drug delivery, including delivery of e.g. insulin for the treatment of diabetes, dopamine receptor agonists employed within the scope of therapies for neurodegenerative diseases, interferone β for the treatment of multiple sclerosis and therapeutic agents based on monoclonal antibodies in treating oncology. Furthermore, the invention may find application as a patient controlled analgesia device for the purpose of pain management.
These and other aspects of the invention are apparent from and will be elucidated with reference to the examples described hereinafter.
BRIEF DESCRIPTION OF THE DRAWINGS
Figure 1 schematically depicts a longitudinal section of an embodiment of the system according to the invention, wherein a drug cartridge loading device comprises a storing unit for storing a plurality of drug cartridges.
Figure 2 schematically displays an embodiment of the method according to the invention. Figure 3 provides a three dimensional view of a schematically depicted embodiment of the drug delivery device according to the invention and the drug cartridge according to the invention.
Figure 4 provides a three dimensional view of a schematically depicted embodiment of the drug cartridge loading device according to the invention.
DETAILED DESCRIPTION OF THE EMBODIMENTS
Figure 1 schematically shows a system 102 comprising a drug cartridge loading device 104, a drug cartridge 106 and a drug delivery device 108. The drug cartridge 106 comprises a medication 107. The drug cartridge loading device 104 comprises a storing unit 110, a receiving unit 112 and a transferring unit 114. In this embodiment, the storing unit is capable of storing a plurality 116 of drug cartridges 106. The medication comprised in the plurality of drug cartridges may differ from one drug cartridge to another drug cartridge, depending on the therapeutic regime. As a result, the patient is allowed to autonomously take his or hers medication during a significant period of time. The receiving unit 112 comprises a guiding geometry 118 for cooperation with a following geometry 120 part of the drug delivery unit 106, which geometries are rotational symmetric for instance.
The transferring unit 114 comprises an electromagnet 122, which electromagnet 122 is supplied by an electric current through an actuator 124 during use. The electromagnet 122 is configured for cooperation with a first permanent magnet 126 provided in the drug cartridge 106. Herein, cooperation between the electromagnet 122 and the first permanent magnet 126 is to be interpreted as providing the electromagnet with a polarization appropriate for attracting the first permanent magnet 126. In case the drug delivery device 108 is received by the receiving unit 112, the presence of the drug delivery device 108 is detected by a presence detector 128 provided in the drug cartridge loading device 104. The presence detector 128 is for instance embodied by means of RFID technology. Herein, the drug delivery device 108 is supplied by a secured passive RFID tag, whereas the drug cartridge loading device 104 is provided with an RFID transponder. A signal provided by the presence detector 128 is a trigger for the actuator 124 to switch off the electric current supplied to the electromagnet 122. Subsequently, a further permanent magnet 130 provided in the drug delivery device 108 will cause the drug cartridge 106 to transfer along a path 133 from the drug cartridge loading device 104 to the drug delivery device 108 by electromagnetically cooperating with a second permanent magnet 132 provided in the drug cartridge 106. By attracting the second permanent magnet 132, the drug cartridge 106 is locked to the further permanent magnet 130 hence it is locked in the drug delivery device 108. Alternatively, upon detecting the presence of the drug delivery unit 108, the current's direction may be alternated to change the polarity of the electromagnet 122 with the purpose of levitating the drug cartridge in order to facilitate the transferring.
A displacing unit 134 provided in the storing unit 110, comprises an actuator 136 to actuate a piston 138 for displacing the plurality 116 of drug cartridges 106 to the transferring unit 114. The actuator 136 is e.g. embodied by a pneumatic cylinder. Alternatively, the actuator 136 may be substituted by a mechanical spring or an electromechanical driver. The displacing unit 134 may alternatively comprise a conveyor belt for displacing the plurality of drug cartridges 116. To facilitate the displacing of the drug cartridges 106 comprised in the plurality of drug cartridges 116, a surface 140 provided in the storing unit may be supplied with a coating for reducing friction. An aperture 142 provided in the storing unit enables a medical professional, or if possible the patient, to refill the storing unit 110 with drug cartridges.
The drug delivery device 108 comprises a further electromagnet 143 which is actuatable by a further actuator 144. The further electromagnet 143 serves for releasing the drug cartridge 106 from the drug delivery device 108. Namely, by manually operating the further actuator 144 through a push button 146, a current is supplied to the further electromagnet such that the magnetic field imposed by the further electromagnet 143 cancels the magnetic field due to the further permanent magnet 130. The latter will cause the drug cartridge 106 which is temporarily accommodated in the drug delivery device 108, to be unlocked. By setting the orientation of the path 133 provided in the drug delivery device 108 in accordance with the gravity field, the drug cartridge 106 will be released from the drug delivery device 108.
The drug cartridge loading device 104 comprises a battery charger 148 known per se. The battery charger 148 is arranged for wirelessly charging a rechargeable battery 150 provided in the drug delivery device 108, which rechargeable battery 150 serves e.g. for energizing the further actuator 144. The drug cartridge loading unit 104 further comprises a display 152 for providing information to the patient or the medical professional, e.g. information regarding the number of cartridges left in the storing unit, a warning that refilling the storing unit is required or an overview of drug delivery data.
The drug delivery device 108 comprises an information consent mechanism 154 containing a consent display 156 and a consent button 158. The consent display 156 notifies the patient that therapy related data, such as the usage of drugs and the utilization of the drug delivery device 108 for the sake of compliance monitoring, is transferred to e.g. a medical professional once the drug delivery device 108 is received by the receiving unit 112 and if the patient activates the consent button 158.
Figure 2 depicts a flowchart schematically representing a method for installing a drug cartridge into a drug delivery device by way of a drug cartridge loading device, which method comprises a step 202 of filling the storing unit provided in the drug cartridge loading device with at least one drug cartridge, but most likely, a plurality of drug cartridges. The step 202 may be carried out by either a patient, a medical professional, or a volunteer aid and the like. Obviously, in case the storing unit is being filled prior to using the drug cartridge loading device, the step 202 can be omitted.
A step 204 comprises storing the drug cartridges in the storing unit. If required by the medication at hand, the storing unit will maintain a storing temperature different from room temperature. A third step 206 comprises receiving the drug delivery device by the receiving unit. Here, receiving implies attaching the drug delivery device and the drug cartridge loading device to one another in such a way that the drug cartridge is appropriately transferrable from the drug cartridge loading device to the drug delivery device. For instance, a guiding geometry may be employed for the purpose of receiving the drug delivery device. The process of attaching the drug cartridge loading device and the drug delivery unit is intended to be performable by the patient. A step 208 comprises transferring the drug cartridge from the drug cartridge loading unit to the drug delivery device, more specifically, the drug cartridge is transferred from the transferring unit provided in the drug cartridge loading unit to the locking unit provided in the drug delivery device. Possibly, the step 208 comprises charging a rechargeable battery provided in the drug delivery device. Alternatively, the rechargeable battery may be charged separate from the loading of the drug cartridge. In addition, during step 208 the information presented on the display can be read.
A step 210 comprises displacing a subsequent drug cartridge from the storing unit to the transferring unit, which transferring unit is emptied by transferring the drug cartridge to the drug delivery device. A step 212 comprises delivering at least a portion of a drug stored in the drug cartridge by way of the drug delivery unit. After emptying the drug cartridge unit through delivering the drug contained in it, a step 214 comprises unlocking the drug cartridge from the locking unit provided in the drug delivery device. The unlocking of the drug cartridge is e.g. realized through switching off the current supplied to the locking unit by manually operating a push button provided in the drug delivery device. Hereafter, a subsequent drug cartridge may be loaded at step 208. An step 216 comprises storing and subsequently environmentally friendly disposing the drug cartridges.
Figure 3 displays a drug delivery device 302 for accommodating a drug cartridge 304. The drug delivery device 302 comprises a display 306 for providing information, e.g. an overview of drug delivery data. The drug delivery device 302 allows for application in a watch- like type of a transdermal drug delivery device.
Figure 4 shows a drug cartridge loading device 402. The drug cartridge loading device 402 comprises a storing unit 404 for storing a drug cartridge and a receiving unit 406 for receiving a drug delivery device. Furthermore, a display 408 is provided for presenting information to the patient or the medical professional, e.g. information regarding the number of cartridges left in the storing unit, a warning that refilling the storing unit is required or an overview of drug delivery data. Furthermore, the display 408 is accompanied by a set of interaction buttons 410 to adjust settings of the drug cartridge loading unit or the drug delivery device. By connecting the drug cartridge loading device 402 to the internet, the information presented in the display 408 or more advanced information not presented in the display 408, may be communicated to the medical professional on a remote location from the patient. For this purpose, the patient is required to push a further button 412 within the context of an information consent step. The latter is important with regard to the patient's privacy. The drug cartridge loading device 402 further comprises a transferring unit, which is not visible in the figure.
While the invention has been illustrated and described in detail in the drawings and in the foregoing description, the illustrations and the description are to be considered illustrative or exemplary and not restrictive. The invention is not limited to the disclosed embodiments. It is noted that the device to the invention and all its components can be made by applying processes and materials known per se. In the set of claims and the description the word "comprising" does not exclude other elements and the indefinite article "a" or "an" does not exclude a plurality. Any reference signs in the claims should not be construed as limiting the scope. It is further noted that all possible combinations of features as defined in the set of claims are part of the invention.

Claims

CLAIMS:
1. A drug cartridge loading device (104, 402) for loading a drug cartridge (106, 304) to a drug delivery device (108, 302) arranged for accommodating a drug cartridge, comprising a storing unit (110, 404) for storing a drug cartridge, - a receiving unit (112, 406) for receiving the drug delivery device, a transferring unit (114) for transferring the drug cartridge to the drug delivery device during or after receiving the drug delivery device.
2. The drug cartridge loading device according to claim 1, comprising a display (152, 408) for providing information regarding the drug cartridge loading device.
3. The drug cartridge loading device according to claim 1, comprising a displacing unit (134) for displacing the drug cartridge from the storing unit to the transferring unit.
4. The drug cartridge loading device according to claim 1, comprising a battery charger (148) for charging a rechargeable battery (150) of the drug delivery device after receiving the drug delivery device.
5. The drug cartridge loading device according to claim 1, wherein the transferring unit comprises an electromagnet (122) configured for cooperation with a first permanent magnet (126) provided in the drug cartridge.
6. A drug delivery device (108, 302), comprising a locking mechanism (130, 132) configured for locking a drug cartridge (106) after being transferred by the transferring unit (114) according to claim 1.
7. The drug delivery device according to claim 6, wherein the locking mechanism is also configured for unlocking the drug cartridge (106).
8. The drug delivery device according to claim 6, wherein the locking mechanism comprises a further permanent magnet (130) arranged for cooperation with a second permanent magnet (132) provided in the drug cartridge.
9. The drug delivery device according to claim 8, wherein the locking mechanism comprises a further electromagnet (143) arranged for cooperation with the second permanent magnet (132) provided in the drug cartridge.
10. The drug delivery device according to claim 6, comprising an information consent mechanism (154).
11. A drug cartridge (106, 304) comprising a first permanent magnet (126) configured for cooperation with the electromagnet (122) provided in the drug cartridge loading device (104, 402) and a second permanent magnet (132) configured for cooperation with the further permanent magnet (130) provided in the drug delivery device (108, 302) and the further electromagnet (143) provided in the drug delivery device.
12. A drug delivery system comprising a drug delivery device (108, 302) for accommodating a drug cartridge (106, 304), and a drug cartridge loading device (104, 402) arranged for loading the drug cartridge to the drug delivery device, wherein the drug cartridge loading device comprises a storing unit (110, 404) for storing a drug cartridge, a receiving unit (112, 406) for receiving the drug delivery device, a transferring unit (114) for transferring the drug cartridge to the drug delivery device during or after receiving the drug delivery device.
13. A method for installing a drug cartridge into a drug delivery device, employing the drug delivery system according to claim 10, and comprising the steps of storing the drug cartridge in the storing unit, - receiving the drug delivery unit by the receiving unit, transferring the drug cartridge from the drug cartridge loading unit to the drug delivery device by the transferring unit.
PCT/IB2009/054213 2008-10-01 2009-09-25 Drug delivery system WO2010038182A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08165562 2008-10-01
EP08165562.3 2008-10-01

Publications (2)

Publication Number Publication Date
WO2010038182A2 true WO2010038182A2 (en) 2010-04-08
WO2010038182A3 WO2010038182A3 (en) 2010-06-17

Family

ID=41396164

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2009/054213 WO2010038182A2 (en) 2008-10-01 2009-09-25 Drug delivery system

Country Status (1)

Country Link
WO (1) WO2010038182A2 (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103079607A (en) * 2010-08-26 2013-05-01 康尔福盛303公司 Iv pump with controllable magnetic field
WO2014085258A1 (en) * 2012-11-29 2014-06-05 Board Of Regents, The University Of Texas System Robotic infusion mixer and transportable cartridge
US9616171B2 (en) 2013-08-05 2017-04-11 Cam Med Llc Conformable patch pump
US10463572B2 (en) 2017-07-07 2019-11-05 Neuroderm, Ltd. Device for subcutaneous delivery of fluid medicament
WO2022150332A1 (en) * 2021-01-08 2022-07-14 Eli Lilly And Company Hub for reusable drug-delivery device
US11779697B2 (en) 2017-07-07 2023-10-10 Neuroderm, Ltd. Device for subcutaneous delivery of fluid medicament
GB2622866A (en) * 2022-09-30 2024-04-03 Owen Mumford Ltd Syringe apparatus

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995034333A2 (en) * 1994-06-03 1995-12-21 Antonio Nicholas F D Hypodermic fluid dispenser
WO2003015846A2 (en) * 2001-08-21 2003-02-27 D'antonio Consultants International, Inc. Hypodermic jet injection kit
EP1757320A1 (en) * 2005-08-25 2007-02-28 Eiholzer, Urs Administration device
EP1961436A1 (en) * 2007-02-24 2008-08-27 Roche Diagnostics GmbH Infusion system

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995034333A2 (en) * 1994-06-03 1995-12-21 Antonio Nicholas F D Hypodermic fluid dispenser
WO2003015846A2 (en) * 2001-08-21 2003-02-27 D'antonio Consultants International, Inc. Hypodermic jet injection kit
EP1757320A1 (en) * 2005-08-25 2007-02-28 Eiholzer, Urs Administration device
EP1961436A1 (en) * 2007-02-24 2008-08-27 Roche Diagnostics GmbH Infusion system

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103079607A (en) * 2010-08-26 2013-05-01 康尔福盛303公司 Iv pump with controllable magnetic field
EP2608822A2 (en) * 2010-08-26 2013-07-03 Carefusion 303 Inc. Iv pump with controllable magnetic field
EP2608822A4 (en) * 2010-08-26 2014-03-12 Carefusion 303 Inc Iv pump with controllable magnetic field
WO2014085258A1 (en) * 2012-11-29 2014-06-05 Board Of Regents, The University Of Texas System Robotic infusion mixer and transportable cartridge
US9616171B2 (en) 2013-08-05 2017-04-11 Cam Med Llc Conformable patch pump
US10398832B2 (en) 2013-08-05 2019-09-03 Cam Med Ltd. Conformable patch pump
US10463572B2 (en) 2017-07-07 2019-11-05 Neuroderm, Ltd. Device for subcutaneous delivery of fluid medicament
US10463787B2 (en) 2017-07-07 2019-11-05 Neuroderm, Ltd. Device for subcutaneous delivery of fluid medicament
US10603430B2 (en) 2017-07-07 2020-03-31 Neuroderm, Ltd. Device for subcutaneous delivery of fluid medicament
US11779697B2 (en) 2017-07-07 2023-10-10 Neuroderm, Ltd. Device for subcutaneous delivery of fluid medicament
WO2022150332A1 (en) * 2021-01-08 2022-07-14 Eli Lilly And Company Hub for reusable drug-delivery device
GB2622866A (en) * 2022-09-30 2024-04-03 Owen Mumford Ltd Syringe apparatus

Also Published As

Publication number Publication date
WO2010038182A3 (en) 2010-06-17

Similar Documents

Publication Publication Date Title
WO2010038182A2 (en) Drug delivery system
US10946137B2 (en) Hybrid ambulatory infusion pumps
US10828417B2 (en) Infusion pumps and inserters for use with same
JP6818008B2 (en) Aerosol delivery system and related methods
US20180085522A1 (en) Infusion Pump Systems and Methods
JP5222849B2 (en) Needle injector device
JP5436653B2 (en) Infusion medium delivery device using a drive device for driving a plunger in a storage container
CN105102024B (en) It is suitable for the recording equipment of dosage combination
AU2018318403B2 (en) Patch pump
US20110098676A1 (en) Systems and methods for delivering drugs
CN106413781A (en) Logging device operated by drug delivery device
CN103228303A (en) Infusion pumps
CA3013434C (en) Hybrid ambulatory infusion pump with contactless power transmission
WO2024017610A1 (en) Safety mechanism for a drug delivery device
US20240001025A1 (en) Hub for reusable drug-delivery device
KR101842348B1 (en) System for injecting medicine
JP2023554091A (en) Communication module for auto-injectors
US20230238105A1 (en) Drug delivery device with increased safety
JP2021097832A (en) Pump system

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09787301

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase in:

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 09787301

Country of ref document: EP

Kind code of ref document: A2