WO2010009648A1 - Pompe à injection médicale - Google Patents

Pompe à injection médicale Download PDF

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Publication number
WO2010009648A1
WO2010009648A1 PCT/CN2009/072616 CN2009072616W WO2010009648A1 WO 2010009648 A1 WO2010009648 A1 WO 2010009648A1 CN 2009072616 W CN2009072616 W CN 2009072616W WO 2010009648 A1 WO2010009648 A1 WO 2010009648A1
Authority
WO
WIPO (PCT)
Prior art keywords
medical syringe
syringe pump
actuator
controller
pump according
Prior art date
Application number
PCT/CN2009/072616
Other languages
English (en)
Chinese (zh)
Inventor
罗七一
王勤
曾志海
刘宇程
杨平中
Original Assignee
微创医疗器械(上海)有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 微创医疗器械(上海)有限公司 filed Critical 微创医疗器械(上海)有限公司
Publication of WO2010009648A1 publication Critical patent/WO2010009648A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers

Definitions

  • the present invention relates to a micropump, and more particularly to a medical syringe pump. Background technique
  • Existing medical syringe pumps include syringe pumps such as insulin pumps and analgesic pumps.
  • Insulin pumps are the best way to treat diabetes, but because existing insulin pumps are expensive, most people with diabetes have not yet had the opportunity to receive this advanced treatment for effective treatment.
  • FIG 1 is an exploded view of the composition of an existing insulin pump.
  • the existing insulin pump is driven by the motor 101 through the shifting device 102 to drive the screw 105 to rotate, and the silk core 106 is moved in the axial direction to push the piston 104 of the syringe 103 to output the liquid medicine to the infusion device matched with the syringe.
  • a display 107 and a keyboard 108 are also disposed on the conventional insulin pump housing 109.
  • the power section of the conventional insulin pump uses an escapement mechanism in addition to the motor 101.
  • FIG 2 is a structural view of an infusion set used in an existing insulin pump.
  • the infusion set used in existing insulin pumps generally consists of a joint 111, a line 112 and an indwelling needle 113, which is connected to the syringe 103 of the pump, and the indwelling needle 113 is inserted under the skin of the human body.
  • Some infusion set lines 112 are broken into two sections, and the intermediate unit is splitter 114. The function of the splitter is to disconnect the pump and the indwelling needle for use in places such as bathing.
  • the liquid medicine in the syringe 103 is sent to the human skin through the infusion tube line 112 through the indwelling needle 113.
  • the present invention provides a medical injection pump, the medical injection pump
  • the utility model comprises a controller, an actuator, a pump core and a medicine cartridge for storing the liquid medicine connected to the pump core input passage, and an indwelling needle communicating with the output passage of the pump core;
  • the actuator controls the pump core to inject the medical solution through the indwelling needle according to an injection command sent by the controller.
  • the executor is further configured to receive a clock collation command sent by the controller.
  • the unit communicates.
  • the medical syringe pump includes a display unit coupled to the controller.
  • the controller receives the injection command via an input device coupled to the controller.
  • the input device is specifically a keyboard or a touch screen or a computer.
  • the medical syringe pump further includes a fault detecting unit connected to the actuator for detecting the working condition of the actuator, and feeding back the result to the controller through the wireless communication unit.
  • the pump core is specifically a piezoelectric ceramic pump core.
  • the medical syringe pump further includes a pressure sensor coupled to the actuator for sensing the pressure at the indwelling needle.
  • the medical syringe pump further includes a storage unit connected to the actuator and the pressure sensor for storing a preset pressure/flow comparison table.
  • the actuator calculates the control amount based on the pressure/flow comparison table of the pressure value measured by the current pressure sensor.
  • the storage unit stores an accumulated working time of the pump core and the indwelling needle.
  • the medical syringe pump further comprises a high pressure distributor connected to the actuator, the high pressure distributor is connected to the high voltage generator, receives the high voltage signal of the high voltage generator, and is converted into the pump core. AC signal.
  • the high voltage generator is connected to the high voltage distributor via a step-up transformer and a rectifier.
  • the high voltage distributor specifically comprises four triodes.
  • the medical syringe pump further includes an external memory connected to the actuator for recording information of the actuator.
  • the controller and the actuator are implemented by using a chip or a single chip microcomputer.
  • the medical syringe pump further includes an alarm connected to the controller.
  • the medical syringe pump further includes a current/voltage detecting circuit coupled to the actuator.
  • the medical injection pump is an insulin pump or an analgesic pump.
  • the medical syringe pump of the embodiment of the invention includes a controller, an actuator, a pump core and a cartridge, and an indwelling needle in communication with the pump core.
  • the controller is capable of receiving an instruction of a user, and converting the instruction to the actuator; the actuator controls the movement of the pump core according to the converted instruction of the controller, thereby causing the The drug solution in the drug cartridge reaches the indwelling needle through the pump core to achieve injection.
  • the controller can easily and accurately control the injection action of the actuator through the controller.
  • the catheter is not required, and the actuator can be applied to the skin surface for the convenience of the patient.
  • Figure 1 is an exploded view of the composition of the existing insulin pump
  • Figure 2 is a structural view of an infusion set used in an existing insulin pump
  • Figure 3 is a working relationship diagram of the first embodiment of the medical syringe pump of the present invention.
  • Figure 4 is a pressure/flow control curve of the piezoelectric ceramic pump of the present invention.
  • Figure 5 is a schematic diagram of a first embodiment of the actuator of the present invention.
  • Figure 6 is a circuit diagram of a first embodiment of the controller of the present invention.
  • Figure 7 is a structural diagram of a first embodiment of the controller of the present invention.
  • Figure 8 is an exploded view of the structure of the controller shown in Figure 7;
  • FIG. 9 is a block diagram of a controller circuit according to an embodiment of the present invention.
  • Figure 10 is an outline view of an actuator according to an embodiment of the present invention.
  • Figure 11 is a structural exploded view of the actuator of the embodiment of the present invention
  • Figure 12 is a block diagram of an actuator circuit in accordance with an embodiment of the present invention. detailed description
  • the invention provides a medical injection pump for facilitating the use of a patient.
  • the medical injection pump according to the first embodiment of the present invention includes a controller 1, an actuator 2, a pump core 3, and a medicine cartridge 4 for storing a liquid medicine in communication with an input passage of the pump core 3, and the pump core
  • the indwelling needle 5 of the output passage of 3 is connected.
  • the medicine cartridge 4, the pump core 3 and the indwelling needle 5 can be made in one piece to constitute a disposable consumable.
  • the user can replace the disposable consumables as a whole. This can better ensure the accuracy of the interaction between the cartridge 4, the pump core 3 and the indwelling needle 5.
  • the controller 1 receives an injection command and converts the instruction into an injection command recognized by the actuator 2 to the actuator 2.
  • FIG. 7 is a structural view of a first embodiment of the controller of the present invention.
  • FIG. 8 is an exploded view of the structure of the controller shown in FIG.
  • the controller 1 may include a keyboard mask 310, an upper casing 311, a display 312, a circuit board 313, a lower casing 314, a battery 316, and a battery cover 315.
  • the controller 1 implements a corresponding control input via the keyboard 301.
  • the insulin pump requires a human-machine dialogue
  • the human-machine dialogue device requires a large display and keyboard. If it is mounted on an actuator attached to the patient's skin, the actuator is bulky and inconvenient for the patient to operate. Therefore, the above problem can be solved by setting the human-machine dialog device on the controller.
  • FIG. 10 is an outline view of an actuator according to an embodiment of the present invention
  • FIG. 11 is an exploded view of the structure of the actuator according to the embodiment of the present invention.
  • the actuator 2 of the embodiment of the present invention may include a protective cover 411, an upper casing 412, a lower casing 415, a bracket 414, a circuit board 413, and a first battery 419.
  • Ben The actuator 2 of the embodiment of the invention may further comprise a disposable consumable consisting of a medicine cartridge 4, a pump core 3, an indwelling needle 5, and a sensor circuit 418.
  • the disposable consumable can be replaced and can be secured within the bracket 414 by insertion and screwing.
  • the indwelling needle 5 of the embodiment of the present invention is directly mounted on the pump core, and the pump core 3 is applied to the skin of the patient.
  • Conventional insulin pumps are difficult to meet the requirements of applying a pump to human skin, both in terms of volume and weight.
  • the actuator 2 of the embodiment of the present invention changes the syringe to the medicine 4, reducing the volume by half.
  • the function of the motor, reducer and lead screw in the existing syringe pump is realized by the pump core 3, which can reduce the volume and weight by more than 80%.
  • the pump core 3 can be specifically a piezoelectric ceramic pump core.
  • the human-machine dialog device is implemented by a second display 312 and a second keyboard 301 installed on the controller 1.
  • the controller 1 realizes the control of the actuator 2 by means of remote control, so that the volume of the actuator applied to the human body is not affected by the human-machine dialogue device.
  • the medical syringe pump of the present invention has a volume and weight reduction of 2/3, which can meet the requirements of application to human skin.
  • the actuator 2 controls the pump core 3 to inject the liquid medicine through the indwelling needle 5 in accordance with an injection command sent from the controller 1.
  • the drug solution 4 can be made of a soft material such as medical high polymer, which needs to ensure good sealing effect and corrosion resistance.
  • the liquid medicine in the medicine cartridge 4 can be transported to the input channel of the pump core 3 under the action of the pump core 3, and transmitted to the output channel through the pump core 3, and then passed through the indwelling communication with the output passage of the pump core 3. Needle 5 is injected into the patient.
  • the pump core 3 includes an actuating device that performs a corresponding operation according to the actuator 2, and a drug storage cavity formed between the actuating device and the pump body, and is connected to the drug storage cavity.
  • An input check valve is arranged in the input channel, and an output check valve is arranged in the output channel.
  • the medicine cartridge 4 is in communication with the input passage of the pump core 3, and the indwelling needle 5 is in communication with the pump core output passage.
  • the actuating device of the pump core 3 is controlled to open according to the injection command sent by the actuator 2
  • the check valve is input, and the output check valve is closed, so that the liquid medicine in the medicine cartridge 4 is input to the drug storage chamber in the pump core 3.
  • the control input shut-off valve is closed, and the output check valve is opened, so that the liquid medicine in the drug storage chamber is injected into the patient through the output check valve 5 through the indwelling needle 5.
  • the actuating device can be realized in particular by a piezoelectric ceramic sheet.
  • the pump body is provided with a mounting groove for mounting the piezoelectric ceramic piece.
  • the pump core 3 can be designed in a cylindrical shape
  • the medicine cartridge 4 can be designed in the shape of a ring having an inner diameter slightly larger than the outer diameter of the pump core 3.
  • the indwelling needle 5 can be kept inserted into the patient's body for a long period of time.
  • the injection of the liquid medicine it is only necessary to send an injection command to the actuator 2 through the controller 1, and then the injection command is converted by the actuator 2 into an injection signal that the pump core 3 can recognize, thereby controlling the pump core 3.
  • the actuation device performs a corresponding operation to effect injection of the indwelling needle 5 to the patient.
  • the controller 1 receives the user's instruction and converts the command into a command that the actuator 2 can recognize and sends it to the actuator 2.
  • the actuator 2 converts the command sent by the controller 1 into an injection signal that the pump core 3 can recognize, and controls the pump core 3 to perform the corresponding action.
  • the indwelling needle 5 injects the medical solution to the user by the corresponding action of the pump core 3.
  • the controller 1 of the medical syringe pump is capable of receiving a user's instruction, and transforms the command to the actuator 2.
  • the actuator 2 is converted to an injection signal recognizable by the pump core 3 according to the command converted by the controller 1, and controls the action of the pump core 3.
  • the injectable solution of the indwelling needle 5 is controlled by the action of the pump core 3.
  • the controller 1 can conveniently and accurately control the injection action of the indwelling needle 5 through the controller 1.
  • the medicine cartridge 4 is directly connected to the pump core 3, and the pump core 3 is directly connected to the indwelling needle 5, a catheter is not required, which is convenient for the patient to use.
  • the controller 1 can communicate with the wireless communication unit of the actuator through a wireless transceiver unit.
  • the controller 1 may be a signal transmitting device similar to a remote controller for triggering the actuator 2 to execute a corresponding command while receiving corresponding feedback from the actuator 2.
  • the controller 1 may display an injection instruction of the controller through a display unit connected to the controller 1.
  • the display unit may specifically be a display screen embedded in the surface of the controller 1, and the control interface of the controller 1 is displayed through the display screen.
  • the controller 1 can receive an instruction of the user through an input device connected to the controller 1, and specifically can be an injection instruction, a calibration clock instruction, a setting of a liquid concentration command, setting an infusion curve instruction, and temporarily closing the input. Note instructions, display history commands, etc.
  • the injection command specifically refers to an instruction sent by the controller 1 to the actuator 2 to control the injection of the indwelling needle 5.
  • Actuator 2 needs to control the indwelling needle 5 injection according to the specific time interval sent by controller 1. Therefore, the clock accuracy of actuator 2 is important.
  • the controller 1 needs to transmit a calibration clock command for adjusting the clock of the actuator 2 to the actuator 2.
  • the controller 1 can send a setting liquid medicine concentration command for setting the concentration of the drug solution in the medicine cartridge 5 to the actuator 2.
  • the user and the medical syringe pump can set the infusion curve and the basic volume infusion curve, and the infusion curve command can also be sent to the actuator 2 through the controller 1.
  • Actuator 2 will perform a 24-hour base infusion in accordance with the basal volume infusion curve.
  • the controller 1 can send a temporary closing infusion command to the actuator 2.
  • the controller 1 can send a display history instruction to the actuator 2.
  • the input device may be a keyboard or stylus designed integrally with the controller 1, or may be a well-known input device (including a computer) externally connected to the controller 1.
  • the input device can input the control command in the form of a touch screen.
  • the display function of the display unit can also be implemented through a touch screen.
  • the medical syringe pump may further include a fault detecting unit connected to the actuator 2 for detecting the working condition of the actuator 2, and Returning the result to the wireless communication unit The wireless transceiver unit of the controller 1.
  • the fault detecting unit simultaneously monitors the software working state and the communication state of the controller 1 and the actuator 2, and finds that the fault is reported to the user in time.
  • the fault detecting unit may be configured to detect a process of the actuator 2 in receiving the controller 1 injection command, converting the injection command to a signal recognizable by the pump core 3, and transmitting the signal to the pump core 3 The working condition of the process, and can feedback the result of the test to the controller 1 in time.
  • the medical syringe pump further includes a pressure sensor connected to the actuator 2 for sensing the pressure at the indwelling needle 5.
  • the medical syringe pump can also include a storage unit coupled to the actuator and the pressure sensor for storing a calibrated pressure/flow meter.
  • the pressure sensor is for transmitting the sensed indwelling needle 5 outlet pressure to the actuator 2 through a pressure value converted into an electrical signal by a lead connected to the actuator 2.
  • the actuator corrects the work command to the actuator based on the calibrated pressure/flow table to achieve a more accurate output.
  • the pressure sensor can sense that the indwelling needle 5 is clogged and the indwelling needle 5 is disengaged. When the crystallization of the drug occludes, the output pressure increases and the pressure sensor will report a blockage; when the output pressure disappears, the pressure sensor will report the needle detachment.
  • FIG. 4 there is shown a pressure/flow control curve for a piezoelectric ceramic pump of the present invention. Since the pressure/flow contrast curve of the piezoceramic pump is non-linear, the voltage or length of time required for the action of the piezoceramic is different under different pressures to ensure the required flow rate. Therefore, the use of a pressure/flow comparison table in a piezoceramic pump ensures accurate flow.
  • the pre-set pressure/flow comparison table of the present invention was measured experimentally.
  • each medical injection pump core needs to perform a pressure/flow test at the time of production, and the pressure/flow rate as shown in FIG. 4 is measured and drawn. Compare the curve and store the comparison table in the memory placed with the sensor. This is the calibration of the pump heart.
  • the specific flow command is issued by the controller 1, and the actuator 2 obtains a specific correction according to the pressure/flow comparison table described above and then performs the corresponding operation.
  • the medical syringe pump is used to store a memory of a preset pressure value, and may also be responsible for storing a threshold value of the accumulated working time of the pump core 3 and the operating time of the pump core 3.
  • the actuator 2 may reject the injection command sent by the controller 1, or may be performed by an alarm connected to the controller 1. An alarm to prompt the user to replace the new disposable consumable.
  • FIG. 12 is a block diagram of an actuator circuit according to an embodiment of the present invention.
  • the control core of the actuator 2 in the embodiment of the present invention is a first CPU, and the first CPU can control the start and stop of the high voltage generator and the voltage level, and can also control the working frequency and duty ratio of the high voltage distributor.
  • the high voltage distributor converts the DC high voltage into an AC high voltage output to the piezoelectric ceramic electrodes.
  • the first CPU communicates with the controller 1 via the wireless communication unit, accepts instructions and returns a work report.
  • the sensor and the memory are mounted on the pump core of the disposable consumable.
  • the sensor detects the pump output pressure.
  • the pressure and flow curves of the pump core are calibrated before leaving the factory.
  • the pressure and flow correspondence are stored in the same circuit as the sensor. On the board's memory.
  • the first CPU determines the voltage of the high voltage generator according to the output pressure, and controls the frequency and duration of the high voltage distributor to ensure the accuracy of the output flow.
  • the sensor can also be responsible for alarming when the needle is blocked and when the needle is detached from the body. While the battery is providing power, the first CPU can also detect the battery level.
  • FIG. 5 there is shown a schematic diagram of a first embodiment of the actuator of the present invention.
  • the medical syringe pump further includes a high pressure distributor connected to the actuator, high pressure
  • the high voltage generated by the generator is converted into a unidirectional pulsating direct current or bidirectional alternating current required by the actuator by the high pressure distributor to drive the actuating device of the pump core 3.
  • the actuator 2 uses the chip U1 or the single chip microcomputer to realize the intelligent control of the infusion and the detection of the working process.
  • the wireless communication unit can be implemented by the chip U4, and the chip U4 is used to communicate with the controller 1.
  • ADO is used for power supply detection.
  • the high voltage generator is implemented by U3 and its associated circuits.
  • the high voltage generator adopts a switching power supply U3 and is equipped with a step-up transformer L1 and a rectifier D1.
  • the high voltage distributor includes four transistors - Q2, Q3, Q4, Q5, which provide the required bidirectional voltage to an actuator such as a piezoceramic. Since there is no ready-made integrated circuit, this part uses three transistors Q2, Q3, Q4, Q5 to build a triode bridge. Its control is controlled by the actuator U1 through the diodes D2, D3 and through the transistors Ql, Q6 to control the on/off of the triode bridge diagonally.
  • the op amp U2 is used to amplify the signal from the pressure sensor in the pump section.
  • the medical syringe pump may further include a current/voltage detecting circuit connected to the actuator 2 for detecting the voltage and current conditions of the high voltage generator and the high voltage distributor.
  • FIG. 9 there is shown a block diagram of a controller circuit in accordance with an embodiment of the present invention.
  • the second keyboard communicates the operator's instructions to the second CPU.
  • the second CPU can display information to the operator through the second display.
  • the second CPU communicates with the actuator 2 through the wireless transceiver unit when needed; it can also communicate with the computer via the wireless transceiver unit when needed.
  • the second CPU can initiate an alarm alarm when needed.
  • the second battery is used to supply power, and the second CPU can also monitor the power of the second battery. Referring to Figure 6, the figure is a circuit diagram of a first embodiment of the controller of the present invention.
  • the controller 1 is implemented by a chip U1 or a single chip microcomputer.
  • the chip U1 is a control core, and the storage unit is implemented by the chip U2 for storing control data and various records.
  • the input device connected to the controller 1 can realize the man-machine dialogue through the keyboard interface J2 external button.
  • the display unit can be connected to the display through the display interface J1 to display various operations. Interface. U3 is used to power the display to solve its special needs for power.
  • the wireless transceiver unit of the controller 1 can be composed of U4 and its external circuits for communication with the actuator 1.
  • the P6.0 signal is a power supply voltage detection circuit for power display.
  • the alarm connected to the controller can be an LSI buzzer alarm circuit for alerting the user if necessary.
  • the medical syringe pump of the embodiment of the invention can be used for the use of an insulin pump or an analgesic pump.

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne une pompe à injection médicale comprenant les éléments suivants : un dispositif de commande (1); un organe d'exécution (2); une partie centrale de pompe (3) et un réservoir de médicament (4) en communication avec le canal d'entrée de la partie centrale de pompe (3) en vue de stocker un médicament liquide; et une aiguille à demeure (5) en communication avec le canal de sortie de la partie centrale de pompe (3). L'organe d'exécution (2) commande la partie centrale de pompe (3) pour l'injection du médicament liquide via l'aiguille à demeure (5), conformément aux ordres d'injection envoyés par le contrôleur (1).
PCT/CN2009/072616 2008-07-25 2009-07-03 Pompe à injection médicale WO2010009648A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2008100410655A CN101632847B (zh) 2008-07-25 2008-07-25 一种医用注射泵
CN200810041065.5 2008-07-25

Publications (1)

Publication Number Publication Date
WO2010009648A1 true WO2010009648A1 (fr) 2010-01-28

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2009/072616 WO2010009648A1 (fr) 2008-07-25 2009-07-03 Pompe à injection médicale

Country Status (2)

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CN (1) CN101632847B (fr)
WO (1) WO2010009648A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102688539A (zh) * 2012-06-15 2012-09-26 江苏绿茵生物科技有限公司 一种胰岛素自动注射系统
CN103599578B (zh) * 2013-12-03 2015-08-05 吉林大学 一种便携式压电驱动胰岛素泵
CN103736168A (zh) * 2014-01-23 2014-04-23 马挺 一种可记录其运行信息的镇痛泵
CN104436362B (zh) * 2014-12-09 2018-03-13 杨利波 一种输注泵
CN110141509A (zh) * 2019-06-10 2019-08-20 舒海华 一种电子镇痛输药方法及系统
CN113244481B (zh) * 2021-05-25 2022-07-05 吉林大学 分体式压电驱动的智能胰岛素贴

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US6589229B1 (en) * 2000-07-31 2003-07-08 Becton, Dickinson And Company Wearable, self-contained drug infusion device
US20040162518A1 (en) * 2000-08-18 2004-08-19 Connelly Robert I. Constant rate fluid delivery device with selectable flow rate and titratable bolus button
CN2659453Y (zh) * 2003-11-21 2004-12-01 王勤 分体式胰岛素泵
CN1726059A (zh) * 2002-11-05 2006-01-25 M2医药有限公司 一种一次性可穿戴的胰岛素分配装置,这种装置和一个程序控制器的组合以及控制这种装置工作的方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6589229B1 (en) * 2000-07-31 2003-07-08 Becton, Dickinson And Company Wearable, self-contained drug infusion device
US20040162518A1 (en) * 2000-08-18 2004-08-19 Connelly Robert I. Constant rate fluid delivery device with selectable flow rate and titratable bolus button
CN1726059A (zh) * 2002-11-05 2006-01-25 M2医药有限公司 一种一次性可穿戴的胰岛素分配装置,这种装置和一个程序控制器的组合以及控制这种装置工作的方法
CN2659453Y (zh) * 2003-11-21 2004-12-01 王勤 分体式胰岛素泵

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CN101632847A (zh) 2010-01-27
CN101632847B (zh) 2012-11-21

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