WO2010004198A3 - Derives anticancereux de 4-oxo-l, 4-dihydro-quinolinξ, leur preparation et leur application en therapeutique - Google Patents
Derives anticancereux de 4-oxo-l, 4-dihydro-quinolinξ, leur preparation et leur application en therapeutique Download PDFInfo
- Publication number
- WO2010004198A3 WO2010004198A3 PCT/FR2009/051322 FR2009051322W WO2010004198A3 WO 2010004198 A3 WO2010004198 A3 WO 2010004198A3 FR 2009051322 W FR2009051322 W FR 2009051322W WO 2010004198 A3 WO2010004198 A3 WO 2010004198A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- quinolinξ
- dihydro
- oxo
- preparation
- therapeutic use
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009801349426A CN102149706A (zh) | 2008-07-08 | 2009-07-06 | 4-氧代-l,4-二氢-喹啉的抗肿瘤的衍生物、其制备方法和其治疗用途 |
JP2011517201A JP2011527321A (ja) | 2008-07-08 | 2009-07-06 | 4−オキソ−l,4−ジヒドロ−キノリンの抗腫瘍性誘導体、それらの調製およびそれらの治療上の使用 |
MX2011000329A MX2011000329A (es) | 2008-07-08 | 2009-07-06 | Derivados anticancerosos de 4-oxo-l, 4-dihidro-quinolina su preparacion y su uso terapeutico. |
AU2009267828A AU2009267828A1 (en) | 2008-07-08 | 2009-07-06 | Antineoplastic derivatives of 4-OXO-L, 4-dihydro-quinoline, preparation thereof, and therapeutic use thereof |
CA2730071A CA2730071A1 (fr) | 2008-07-08 | 2009-07-06 | Derives anticancereux, leur preparation et leur application en therapeutique |
EP09784468A EP2307401A2 (fr) | 2008-07-08 | 2009-07-06 | Derives anticancereux de 4-oxo-1,4-dihydro-quinoline, leur preparation et leur application en therapeutique |
BRPI0915558A BRPI0915558A2 (pt) | 2008-07-08 | 2009-07-06 | compostos anticancerígenos, processo de preparo destes, uso dos mesmos, medicamento e composição farmacêutica |
IL210458A IL210458A0 (en) | 2008-07-08 | 2011-01-04 | Antineoplastic derivatives of 4 - oxo - 1, 4 - dihydro - quinoline, preparation thereof, and therapeutic use thereof |
US12/986,642 US20110251194A1 (en) | 2008-07-08 | 2011-01-07 | Antineoplastic derivatives, preparation thereof and therapeutic use thereof |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0803863 | 2008-07-08 | ||
FR0803863A FR2933701A1 (fr) | 2008-07-08 | 2008-07-08 | Derives anticancereux, leur preparation et leur application en therapeutique |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/986,642 Continuation US20110251194A1 (en) | 2008-07-08 | 2011-01-07 | Antineoplastic derivatives, preparation thereof and therapeutic use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2010004198A2 WO2010004198A2 (fr) | 2010-01-14 |
WO2010004198A3 true WO2010004198A3 (fr) | 2010-03-04 |
Family
ID=40344660
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/FR2009/051322 WO2010004198A2 (fr) | 2008-07-08 | 2009-07-06 | Derives anticancereux, leur preparation et leur application en therapeutique |
Country Status (16)
Country | Link |
---|---|
US (1) | US20110251194A1 (fr) |
EP (1) | EP2307401A2 (fr) |
JP (1) | JP2011527321A (fr) |
KR (1) | KR20110031371A (fr) |
CN (1) | CN102149706A (fr) |
AR (1) | AR072474A1 (fr) |
AU (1) | AU2009267828A1 (fr) |
BR (1) | BRPI0915558A2 (fr) |
CA (1) | CA2730071A1 (fr) |
FR (1) | FR2933701A1 (fr) |
IL (1) | IL210458A0 (fr) |
MX (1) | MX2011000329A (fr) |
RU (1) | RU2011104367A (fr) |
TW (1) | TW201006836A (fr) |
UY (1) | UY31972A (fr) |
WO (1) | WO2010004198A2 (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2933700B1 (fr) * | 2008-07-08 | 2010-07-30 | Sanofi Aventis | Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique |
FR2954943B1 (fr) * | 2010-01-07 | 2013-03-01 | Sanofi Aventis | Derives de pyridino-pyridinones arylsulfonamides, leur preparation et leur application en therapeutique |
FR2955109B1 (fr) * | 2010-01-08 | 2012-09-07 | Sanofi Aventis | Derives de 5-oxo-5,8-dihydro-pyrido[2, 3-d]pyrimidine, leur preparation et leur application en therapeutique |
SI2874625T1 (sl) * | 2012-07-17 | 2017-10-30 | Sanofi | Uporaba inhibitorjev VEGFR-3 za zdravljenje hepatoceličnega karcinoma |
WO2014091265A1 (fr) | 2012-12-11 | 2014-06-19 | Aurigene Discovery Technologies Limited | Dérivés de pyrimidine-2,4-diamine en tant qu'inhibiteurs de kinase |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006016067A2 (fr) * | 2004-07-15 | 2006-02-16 | Sanofi-Aventis | Derives de pyrido-pyrimidine, leur preparation, leur application dans le traitement du cancer |
-
2008
- 2008-07-08 FR FR0803863A patent/FR2933701A1/fr not_active Withdrawn
-
2009
- 2009-07-06 CN CN2009801349426A patent/CN102149706A/zh active Pending
- 2009-07-06 EP EP09784468A patent/EP2307401A2/fr not_active Withdrawn
- 2009-07-06 AU AU2009267828A patent/AU2009267828A1/en not_active Abandoned
- 2009-07-06 CA CA2730071A patent/CA2730071A1/fr not_active Abandoned
- 2009-07-06 WO PCT/FR2009/051322 patent/WO2010004198A2/fr active Application Filing
- 2009-07-06 MX MX2011000329A patent/MX2011000329A/es not_active Application Discontinuation
- 2009-07-06 JP JP2011517201A patent/JP2011527321A/ja not_active Withdrawn
- 2009-07-06 KR KR1020117002860A patent/KR20110031371A/ko not_active Application Discontinuation
- 2009-07-06 BR BRPI0915558A patent/BRPI0915558A2/pt not_active Application Discontinuation
- 2009-07-06 RU RU2011104367/04A patent/RU2011104367A/ru unknown
- 2009-07-07 AR ARP090102533A patent/AR072474A1/es unknown
- 2009-07-08 TW TW098123130A patent/TW201006836A/zh unknown
- 2009-07-08 UY UY0001031972A patent/UY31972A/es not_active Application Discontinuation
-
2011
- 2011-01-04 IL IL210458A patent/IL210458A0/en unknown
- 2011-01-07 US US12/986,642 patent/US20110251194A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006016067A2 (fr) * | 2004-07-15 | 2006-02-16 | Sanofi-Aventis | Derives de pyrido-pyrimidine, leur preparation, leur application dans le traitement du cancer |
Also Published As
Publication number | Publication date |
---|---|
MX2011000329A (es) | 2011-04-05 |
IL210458A0 (en) | 2011-03-31 |
KR20110031371A (ko) | 2011-03-25 |
WO2010004198A2 (fr) | 2010-01-14 |
CN102149706A (zh) | 2011-08-10 |
AR072474A1 (es) | 2010-09-01 |
RU2011104367A (ru) | 2012-08-20 |
CA2730071A1 (fr) | 2010-01-14 |
US20110251194A1 (en) | 2011-10-13 |
TW201006836A (en) | 2010-02-16 |
BRPI0915558A2 (pt) | 2016-01-26 |
EP2307401A2 (fr) | 2011-04-13 |
JP2011527321A (ja) | 2011-10-27 |
FR2933701A1 (fr) | 2010-01-15 |
AU2009267828A1 (en) | 2010-01-14 |
UY31972A (es) | 2010-02-26 |
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