WO2010002940A3 - Heterogeneous synthesis of multivalent chimeric immunomodulatory compounds using platform based molecules - Google Patents

Heterogeneous synthesis of multivalent chimeric immunomodulatory compounds using platform based molecules Download PDF

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Publication number
WO2010002940A3
WO2010002940A3 PCT/US2009/049325 US2009049325W WO2010002940A3 WO 2010002940 A3 WO2010002940 A3 WO 2010002940A3 US 2009049325 W US2009049325 W US 2009049325W WO 2010002940 A3 WO2010002940 A3 WO 2010002940A3
Authority
WO
WIPO (PCT)
Prior art keywords
immunomodulatory compounds
platform based
based molecules
heterogeneous synthesis
multivalent chimeric
Prior art date
Application number
PCT/US2009/049325
Other languages
French (fr)
Other versions
WO2010002940A2 (en
Inventor
Tracy Matray
Karen L. Fearon
Hesham A. Sherif
Original Assignee
Dynavax Technologies Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dynavax Technologies Corporation filed Critical Dynavax Technologies Corporation
Publication of WO2010002940A2 publication Critical patent/WO2010002940A2/en
Publication of WO2010002940A3 publication Critical patent/WO2010002940A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants

Abstract

The invention provides chimeric immunomodulatory compounds, methods for making such compounds and methods for immunomodulation of individuals using the immunomodulatory compounds.
PCT/US2009/049325 2008-06-30 2009-06-30 Heterogeneous synthesis of multivalent chimeric immunomodulatory compounds using platform based molecules WO2010002940A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7709408P 2008-06-30 2008-06-30
US61/077,094 2008-06-30

Publications (2)

Publication Number Publication Date
WO2010002940A2 WO2010002940A2 (en) 2010-01-07
WO2010002940A3 true WO2010002940A3 (en) 2010-07-29

Family

ID=41466585

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/049325 WO2010002940A2 (en) 2008-06-30 2009-06-30 Heterogeneous synthesis of multivalent chimeric immunomodulatory compounds using platform based molecules

Country Status (1)

Country Link
WO (1) WO2010002940A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8003115B2 (en) 2001-06-21 2011-08-23 Dynavax Technologies Corporation Chimeric immunomodulatory compounds and methods of using the same

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3442568A4 (en) * 2016-04-15 2019-12-18 Dynavax Technologies Corporation Intratumoral administration of particles containing a toll-like receptor 9 agonist and a tumor antigen for treating cancer

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030147870A1 (en) * 2000-03-28 2003-08-07 Eyal Raz Methods for increasing a cytotoxic T lymphocyte response in vivo
US6951939B2 (en) * 2000-06-08 2005-10-04 La Jolla Pharmaceutical Company Multivalent platform molecules comprising high molecular weight polyethylene oxide
US20070049550A1 (en) * 2001-06-21 2007-03-01 Dynavax Technologies Corporation Chimeric immunomodulatory compounds and methods of using the same - IV

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030147870A1 (en) * 2000-03-28 2003-08-07 Eyal Raz Methods for increasing a cytotoxic T lymphocyte response in vivo
US6951939B2 (en) * 2000-06-08 2005-10-04 La Jolla Pharmaceutical Company Multivalent platform molecules comprising high molecular weight polyethylene oxide
US20070049550A1 (en) * 2001-06-21 2007-03-01 Dynavax Technologies Corporation Chimeric immunomodulatory compounds and methods of using the same - IV

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8003115B2 (en) 2001-06-21 2011-08-23 Dynavax Technologies Corporation Chimeric immunomodulatory compounds and methods of using the same
US8114418B2 (en) 2001-06-21 2012-02-14 Dynavax Technologies Corporation Chimeric immunomodulatory compounds and methods of using the same—IV
US8597665B2 (en) 2001-06-21 2013-12-03 Dynavax Technologies Corporation Chimeric immunomodulatory compounds and methods of using the same-IV
US9028845B2 (en) 2001-06-21 2015-05-12 Dynavax Technologies Corporation Chimeric immunomodulatory compounds and methods of using the same-IV

Also Published As

Publication number Publication date
WO2010002940A2 (en) 2010-01-07

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