WO2009144462A3 - Laminin receptor binding proteins - Google Patents

Laminin receptor binding proteins Download PDF

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Publication number
WO2009144462A3
WO2009144462A3 PCT/GB2009/001336 GB2009001336W WO2009144462A3 WO 2009144462 A3 WO2009144462 A3 WO 2009144462A3 GB 2009001336 W GB2009001336 W GB 2009001336W WO 2009144462 A3 WO2009144462 A3 WO 2009144462A3
Authority
WO
WIPO (PCT)
Prior art keywords
binding proteins
receptor binding
laminin receptor
antigenic polypeptides
laminin
Prior art date
Application number
PCT/GB2009/001336
Other languages
French (fr)
Other versions
WO2009144462A2 (en
Inventor
Dlawer Ala'aldeen
Kark Wooldridge
Jafar Mahdavi
Original Assignee
The University Of Nottingham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The University Of Nottingham filed Critical The University Of Nottingham
Publication of WO2009144462A2 publication Critical patent/WO2009144462A2/en
Publication of WO2009144462A3 publication Critical patent/WO2009144462A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The present invention relates to antigenic polypeptides expressed by the bacteria Neisseria meningitides and Haemophilus influenzae, vaccines comprising the antigenic polypeptides and therapeutic antibodies directed to the antigenic polypeptides.
PCT/GB2009/001336 2008-05-28 2009-05-28 Laminin receptor binding proteins WO2009144462A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0809659.6A GB0809659D0 (en) 2008-05-28 2008-05-28 Polypeptides
GB0809659.6 2008-05-28

Publications (2)

Publication Number Publication Date
WO2009144462A2 WO2009144462A2 (en) 2009-12-03
WO2009144462A3 true WO2009144462A3 (en) 2010-04-29

Family

ID=39616199

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2009/001336 WO2009144462A2 (en) 2008-05-28 2009-05-28 Laminin receptor binding proteins

Country Status (2)

Country Link
GB (1) GB0809659D0 (en)
WO (1) WO2009144462A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108300682A (en) * 2017-11-13 2018-07-20 山东省农业科学院畜牧兽医研究所 A kind of haemophilus parasuis OmpP2 gene-deleted strains and its construction method and application

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011284809B2 (en) 2010-07-30 2015-04-02 Griffith University Recombinant Neisseria meningitidis Por A porin proteins.
CN104736563A (en) 2012-07-27 2015-06-24 国家健康与医学研究院 Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990006696A2 (en) * 1988-12-19 1990-06-28 Praxis Biologics, Inc. Meningococcal class 1 outer-membrane protein vaccine
WO2004046177A2 (en) * 2002-11-15 2004-06-03 Chiron Srl Unexpected surface proteins in neisseria meningitidis
US7118757B1 (en) * 1988-12-19 2006-10-10 Wyeth Holdings Corporation Meningococcal class 1 outer-membrane protein vaccine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990006696A2 (en) * 1988-12-19 1990-06-28 Praxis Biologics, Inc. Meningococcal class 1 outer-membrane protein vaccine
US7118757B1 (en) * 1988-12-19 2006-10-10 Wyeth Holdings Corporation Meningococcal class 1 outer-membrane protein vaccine
WO2004046177A2 (en) * 2002-11-15 2004-06-03 Chiron Srl Unexpected surface proteins in neisseria meningitidis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE Geneseq [online] 20 November 1990 (1990-11-20), "Antigenic protein fragment of N.meningitidis outer-membrane protein.", retrieved from EBI accession no. GSP:AAR06041 Database accession no. AAR06041 *
DATABASE Geneseq [online] 26 August 2004 (2004-08-26), "Neisseria meningitidis MC58 OMV-related membrane protein - SEQ ID 138.", retrieved from EBI accession no. GSP:ADP08305 Database accession no. ADP08305 *
DATABASE USPTO Proteins [online] 14 August 2007 (2007-08-14), "Sequence 3 from patent US 7238345.", retrieved from EBI accession no. USPOP:ABU32639 Database accession no. ABU32639 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108300682A (en) * 2017-11-13 2018-07-20 山东省农业科学院畜牧兽医研究所 A kind of haemophilus parasuis OmpP2 gene-deleted strains and its construction method and application

Also Published As

Publication number Publication date
GB0809659D0 (en) 2008-07-02
WO2009144462A2 (en) 2009-12-03

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