WO2009141137A3 - New molecule [124i][2-(3'-iodo-4'-methylaminophenyl)-6-hydroxy-benzothialzole] for pet investigations and radiotherapy - Google Patents

New molecule [124i][2-(3'-iodo-4'-methylaminophenyl)-6-hydroxy-benzothialzole] for pet investigations and radiotherapy Download PDF

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Publication number
WO2009141137A3
WO2009141137A3 PCT/EP2009/003605 EP2009003605W WO2009141137A3 WO 2009141137 A3 WO2009141137 A3 WO 2009141137A3 EP 2009003605 W EP2009003605 W EP 2009003605W WO 2009141137 A3 WO2009141137 A3 WO 2009141137A3
Authority
WO
WIPO (PCT)
Prior art keywords
benzothialzole
methylaminophenyl
iodo
hydroxy
radiotherapy
Prior art date
Application number
PCT/EP2009/003605
Other languages
French (fr)
Other versions
WO2009141137A2 (en
Inventor
Domenico Martini
Paola Panichelli
Gianluca Valentini
Original Assignee
Sparkle S.R.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sparkle S.R.L. filed Critical Sparkle S.R.L.
Publication of WO2009141137A2 publication Critical patent/WO2009141137A2/en
Publication of WO2009141137A3 publication Critical patent/WO2009141137A3/en

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
    • B29D35/00—Producing footwear
    • B29D35/12—Producing parts thereof, e.g. soles, heels, uppers, by a moulding technique
    • B29D35/14—Multilayered parts
    • B29D35/142—Soles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

New molecule [124I] [2-(3'-iodo-4'-methylaminophenyl)-6-hydroxy-benzothialzole] obtainable through a chemical synthesis process, starting from the radioisotope Iodine-124[124I] and possessing mainly PET diagnostic imaging properties.
PCT/EP2009/003605 2008-05-23 2009-05-20 New molecule [124i][2-(3'-iodo-4'-methylaminophenyl)-6-hydroxy-benzothialzole] for pet investigations and radiotherapy WO2009141137A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMC2008A000089 2008-05-23
ITMC20080089 ITMC20080089A1 (en) 2008-05-23 2008-05-23 CHEMICAL SYNTHESIS OF I-124 [6-OH-BTA-1-3'-I] IODINE-124 [2- (3'-IODO-4'-METHYLAMINOPHENYL) -6-HYDROXY-BENZOTHIALZOLE] FOR PET AND RADIOTHERAPY INVESTIGATIONS.

Publications (2)

Publication Number Publication Date
WO2009141137A2 WO2009141137A2 (en) 2009-11-26
WO2009141137A3 true WO2009141137A3 (en) 2010-02-25

Family

ID=40302671

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/003605 WO2009141137A2 (en) 2008-05-23 2009-05-20 New molecule [124i][2-(3'-iodo-4'-methylaminophenyl)-6-hydroxy-benzothialzole] for pet investigations and radiotherapy

Country Status (2)

Country Link
IT (1) ITMC20080089A1 (en)
WO (1) WO2009141137A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113480467B (en) * 2021-07-13 2022-12-30 河北维达康生物科技有限公司 Synthesis process of radioactive tracer 2-iodine melatonin

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004083195A1 (en) * 2003-03-14 2004-09-30 University Of Pittsburgh Benzothiazole derivative compounds, compositions and uses

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004083195A1 (en) * 2003-03-14 2004-09-30 University Of Pittsburgh Benzothiazole derivative compounds, compositions and uses

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
M. J. WELCH: "Handbook of Radiopharmaceuticals: Radiochemistry and Applications", 2003, JOHN WILEY AND S, LTD. ONS, ISBN: 0471495603, article R. FINN: "CHEMISTRY APPLIED TO IODINE RADIONUCLIDES", pages: 423 - 440, XP007910861 *
WANG Y ET AL: "Development of a pet / spect agent for amyloid imaging in alzheimer's disease", JOURNAL OF MOLECULAR NEUROSCIENCE, BIRKHAEUSER, CAMBRIDGE, MA, US, vol. 24, 1 January 2004 (2004-01-01), pages 55 - 62, XP008108084, ISSN: 0895-8696 *

Also Published As

Publication number Publication date
ITMC20080089A1 (en) 2008-08-22
WO2009141137A2 (en) 2009-11-26

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